Clinical complementary medicine and pharmacology最新文献

{"title":"Interview and external examination of a rheumatological patient","authors":"E. Belyaeva","doi":"10.12737/2409-3750-2022-8-3-2-10","DOIUrl":"https://doi.org/10.12737/2409-3750-2022-8-3-2-10","url":null,"abstract":"examination of a rheumatological patient should be carried out in the most thorough manner due to the systemic nature of the lesion and the presence of many specific symptoms and syndromes. The speed and correctness of the diagnosis depends on a competently collected anamnesis and a fully conducted physical examination, and therefore, in many respects, the further life prognosis.","PeriodicalId":72608,"journal":{"name":"Clinical complementary medicine and pharmacology","volume":"294 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73524677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE USE OF THE FLUORESCENT DYE INDOCYANINE GREEN IN THE THERANOSTICS OF ONCOLOGICAL DISEASES (literature review)","authors":"A. Guseynov, T. Askarov, T. Guseynov, S. Sedov","doi":"10.12737/2409-3750-2022-8-3-34-39","DOIUrl":"https://doi.org/10.12737/2409-3750-2022-8-3-34-39","url":null,"abstract":"In modern medicine, the fluorescent dye indocyanine green (ICG) is used in the diagnosis and treatment of many diseases, including malignant neoplasms. \u0000The use of ICG is primarily due to such positive properties of the drug as chemical resistance and photostability, unique traceability and high lymphotropicity. \u0000The ICG preparation, as a fluorescent contrast agent, is used in the diagnosis of many diseases, in particular to determine the fraction of cardiac output, the function of blood flow of parenchymal organs (liver, spleen) and in ophthalmology, to assess the blood supply of intestinal anastomoses and in angiography. \u0000ICG is used in oncology in the surgical treatment of tumors. The fluorescent image under the control of infrared radiation makes it possible to identify the structures to be removed (tumor tissue, lymph nodes). \u0000The role of the fluorescent dye ICG in the mapping of signaling lymph nodes in oncology is high. The technique is highly informative in identifying lymph nodes involved in the tumor process, to determine the stage of the tumor, prediction and selection of antitumor therapy. \u0000In addition, ICG is used in photodynamic and photothermal therapy of tumors. Due to its photosensitizing properties, ICG is used to generate forms of oxygen or heat in order to destroy tumor cells.","PeriodicalId":72608,"journal":{"name":"Clinical complementary medicine and pharmacology","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73772546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immunostimulatory and Immunorestorative Effects of Leaf Extract and Fractions of Musanga cecropioides on Immunocompetent and Experimentally Induced Immunocompromised Mice.","authors":"Cyril O. Ogbue, F. A. Onyegbule, C. O. Ezugwu, Ifebi H.M. Nchekwube, A. A. Ajaghaku","doi":"10.1016/j.ccmp.2022.100075","DOIUrl":"https://doi.org/10.1016/j.ccmp.2022.100075","url":null,"abstract":"","PeriodicalId":72608,"journal":{"name":"Clinical complementary medicine and pharmacology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49648480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"METHOD OF GENERALIZED HYGIENIC ASSESSMENT OF TERRITORY POLLU-TION","authors":"V. Hromushin, Aleksandr Hadarcev, R. Grachev","doi":"10.12737/2409-3750-2022-8-2-26-30","DOIUrl":"https://doi.org/10.12737/2409-3750-2022-8-2-26-30","url":null,"abstract":"The relevance of the hygienic assessment of the pollution of the territory of residence is determined by the influence of air pollution on human health. The considered method of generalized assessment allows not only to quantify the pollution of the territory, but also to calculate the share values of the analyzed pollutants, which is important for the formation of priorities for decisions to reduce the pollution of the territory. The proposed method is considered on the example of a specific calculation of the proportion of samples of priority pollutants in excess of the maximum allowable values in the atmospheric air.","PeriodicalId":72608,"journal":{"name":"Clinical complementary medicine and pharmacology","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78764294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"BREAST CANCER TREATMENT","authors":"A. Guseynov, T. Guseynov, M. Bobkov, V. Blincov, V. Odincov","doi":"10.12737/2409-3750-2022-8-2-2-13","DOIUrl":"https://doi.org/10.12737/2409-3750-2022-8-2-2-13","url":null,"abstract":"The article presents up-to-date information for doctors of various specialties: oncologists, surgeons, mammologists, obstetricians and gynecologists, general practitioners on the problems of modern treatment of breast cancer. The issues of treatment tactics, indications and contraindications for surgical, radiation and drug treatment of breast cancer patients are highlighted.","PeriodicalId":72608,"journal":{"name":"Clinical complementary medicine and pharmacology","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78632339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CERVICAL-ISTHMIAN PREGNANCY: A CLINICAL CASE OF GESTATION AND BIRTH OF A CHILD","authors":"V. Cheremiskin, A. Filyanina","doi":"10.12737/2409-3750-2022-8-2-21-23","DOIUrl":"https://doi.org/10.12737/2409-3750-2022-8-2-21-23","url":null,"abstract":"Cervical-isthmian pregnancy is a very rare form of ectopic pregnancy, characterized by the localization of the fetus in the isthmus and cervix. This pathology is associated with disorders of ovum fixation in the uterine body in patients with a burdened obstetric and gynecological history and is characterized by a high risk of maternal mortality due to the possible development of life-threatening complications (DIC syndrome, bleeding). But, unlike other forms of ectopic pregnancy, it is with her that you can carry and give birth to a child. The article presents such a case.","PeriodicalId":72608,"journal":{"name":"Clinical complementary medicine and pharmacology","volume":"193 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73275927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PREGNANCY MANAGEMENT IN HIV-POSITIVE WOMEN","authors":"A. Chernova, M. Maksimova, E. Gadzhiumarova","doi":"10.12737/2409-3750-2022-8-2-24-25","DOIUrl":"https://doi.org/10.12737/2409-3750-2022-8-2-24-25","url":null,"abstract":"The article describes the management of HIV-positive pregnant women. It was shown that pregnancy complications in these women were observed more often in the second trimester of pregnancy. At the same time, the incidence of gestosis, anemia and chronic placental insufficiency decreases against the background of specific antiviral therapy.","PeriodicalId":72608,"journal":{"name":"Clinical complementary medicine and pharmacology","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73690265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hyperuricemia and its clinical significance","authors":"F. Karabaeva","doi":"10.12737/2409-3750-2022-8-2-14-20","DOIUrl":"https://doi.org/10.12737/2409-3750-2022-8-2-14-20","url":null,"abstract":"The issues of the pathogenesis of hyperuricemia currently remain relevant due to the steady increase in the frequency of hyperuricemia and gout in polymorbid pathologies. Currently, a sufficient number of scientific papers have been accumulated on the association of hyperuricemia with cardiovascular diseases and their consequences (stroke and myocardial infarction), metabolic syndrome, arterial hypertension, insulin resistance, type 2 diabetes mellitus, chronic kidney disease, lipid metabolism disorders, atrial fibrillation, with the risk of mortality.","PeriodicalId":72608,"journal":{"name":"Clinical complementary medicine and pharmacology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89857896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Anti-obesity Effect of Allium cepa L. leaves on High Fat Diet Induced Obesity in Male Wistar Rats","authors":"Babafemi J. Momoh,&nbsp;Shekins O. Okere,&nbsp;Gabriel O. Anyanwu","doi":"10.1016/j.ccmp.2022.100035","DOIUrl":"10.1016/j.ccmp.2022.100035","url":null,"abstract":"<div><h3>Background</h3><p>Over the years, there has been research on the anti-obesity effect of the <em>Allium cepa</em> bulb, but a dearth of research was carried out on the leaves, which is consumed as vegetable salad and soup, hence this study was proposed.</p></div><div><h3>Objective</h3><p>This study aims at investigating the effect of <em>A. cepa</em> leaves on high fat diet (HFD) induced obesity in male Wistar rats.</p></div><div><h3>Methods</h3><p>Twenty-eight male Wistar rats were divided into four groups with seven rats each. Apart from Group 1 (normal control which received normal pelleted diet), obesity was induced in 21 rats of Group 2 to 4 with HFD. Group 2, the obese control was administered with 100% HFD, while the diet for group 3 and 4 was supplemented with 10% and 20% <em>A. cepa</em> powdered leaves, respectively, for 28 days.</p></div><div><h3>Results</h3><p>In the rats treated with 10% and 20% <em>A. cepa</em>, body weight, fat mass, blood glucose, total cholesterol, triglycerides, aspartate amino transferase, alanine amino transferase, creatinine and urea levels were reduced significantly (<em>P</em> &lt; 0.05) in comparison with the obese control group. The liver of the rats treated with 10% and 20% <em>A. cepa</em> leaves revealed small and few amounts of fat deposits in comparison with the obese control group, which revealed numerous and large deposits of fat. The kidney of the rats treated with 10% and 20% <em>A. cepa</em> leaves showed moderate and mild inflammation, respectively, in comparison with the obese control group which showed acute inflammation. The leaves of <em>A. cepa</em> had antioxidant properties and the presence of volatile compounds with anti-obesity properties in <em>A. cepa</em> were identified using gas chromatography-mass spectrometry (GC-MS).</p></div><div><h3>Conclusion</h3><p><em>A. cepa</em> leaves had weight-loss effect in that it decreased body weight, fat mass, glucose and lipid levels including fat deposits in the liver.</p></div>","PeriodicalId":72608,"journal":{"name":"Clinical complementary medicine and pharmacology","volume":"2 3","pages":"Article 100035"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S277237122200016X/pdfft?md5=d805fb7c79262b61ab316e98ad9ca7a5&pid=1-s2.0-S277237122200016X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41525356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploration of Pharmacological and Toxicological Properties of Aerial Parts of Blumea lacera, a Common Weed in Bangladesh","authors":"Pritam Kundu,&nbsp;Shovan Lal Debnath,&nbsp;Samir Kumar Sadhu","doi":"10.1016/j.ccmp.2022.100038","DOIUrl":"10.1016/j.ccmp.2022.100038","url":null,"abstract":"<div><h3>Background</h3><p><em>Blumea lacera</em> (Family Asteraceae) is a herb found in the uncultivated lands of many Asian countries. This plant is used by quack doctors for some medicinal purposes.</p></div><div><h3>Objective</h3><p>Works presented in this manuscript were conducted on the ethanol extract of aerial parts of <em>B. lacera</em>. Various pharmacological tests like antioxidant, analgesic, anti-inflammatory, antidiarrheal, diuretic, antibacterial, anthelmintic and toxicological tests like brine shrimp lethality and acute toxicity were evaluated.</p></div><div><h3>Methods</h3><p>Antioxidant test was conducted by determining secondary metabolites content and DPPH free radical scavenging assay. Acetic acid-induced writhing method, xylene-induced ear edema method, castor oil-induced diarrheal method, and urinary volume test were performed to evaluate the analgesic, anti-inflammatory, antidiarrheal and diuretic effects, respectively. The antibacterial test was performed by disk diffusion method, anthelmintic activity by recording the paralysis and death time of <em>P. cervi</em> and finally, cytotoxic activity was performed by brine shrimp lethality bioassay.</p></div><div><h3>Results</h3><p>TPC, TFC and TTC contents of <em>B. lacera</em> extract were found to be 9 mg GAE/g, 31 mg QE/g and 18 mg GAE/g. The SC₅₀ value of the DPPH radical scavenging assay was found to be higher than 3000 µg·mL^-¹. The LD₅₀ value of <em>B. lacera</em> extract in mice was higher than 5000 mg·kg^-¹. This extract significantly inhibited writhing reflexes by 24.5% and 43.6% and reduced ear edema up to 24.6% and 41% at 250 and 500 mg·kg^-¹ bw doses, respectively. It also increased the latency of the first defecation period up to 52.8 min and 106.6 min as well as decreased the stool count by 34.1% and 48.2% at 250 and 500 mg·kg^-¹ bw doses, respectively. It also showed an increase in urinary output in the diuretic test. Good antibacterial activity of <em>B. lacera</em> extract was confirmed by retardation in bacterial growth and significantly killed <em>P. cervi</em> in a dose-dependent manner. In brine shrimp lethality bioassay, the LC₅₀ value was found to be 5.4 µg·mL^-¹.</p></div><div><h3>Conclusion</h3><p><em>B. lacera</em> showed mild analgesic, anti-inflammatory and antidiarrheal properties. It could be used as a diuretic, antibacterial, anthelmintic and cytotoxic drug which justify the plant's traditional uses in folk medicine.</p></div>","PeriodicalId":72608,"journal":{"name":"Clinical complementary medicine and pharmacology","volume":"2 3","pages":"Article 100038"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772371222000195/pdfft?md5=682e57c7675695288a632ce451daa145&pid=1-s2.0-S2772371222000195-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49597582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}