Child neurology open最新文献_第3页

Anti-SOX1 Antibodies in a 3-Year-old Girl, Post-Varicella. 水痘后3岁女孩体内的抗SOX1抗体。

Child neurology open Pub Date : 2023-09-21 eCollection Date: 2023-01-01 DOI: 10.1177/2329048X231200613

Aline Wijnand, Helene Verhelst

{"title":"Anti-SOX1 Antibodies in a 3-Year-old Girl, Post-Varicella.","authors":"Aline Wijnand, Helene Verhelst","doi":"10.1177/2329048X231200613","DOIUrl":"https://doi.org/10.1177/2329048X231200613","url":null,"abstract":"Anti-SRY-related HMG-box gene 1 (SOX1) antibodies were initially described in adults with paraneoplastic neurological disorders, where they are considered high-risk onconeural autoantibodies. Only two pediatric cases of anti-SOX1 antibodies have been reported: a 17-year-old adolescent presenting with paraneoplastic limbic encephalitis due to Hodgkin lymphoma and a 12-year-old girl presenting with non-paraneoplastic encephalitis. We present a unique case of anti-SOX1 antibodies in a 3-year-old girl, post-varicella infection. Initially, she presented with ataxia and dysmetria, with subsequent reports from parents of urinary incontinence and significant behavior changes. Additionally, reflexes in the lower limbs were absent. Anti-SOX1 antibodies tested positive in both serum and cerebrospinal fluid. Oncological screening at presentation and a seven-month follow-up showed no malignancies. The patient exhibited favorable clinical progress without requiring treatment. At the seven-month follow-up, serum antibodies tested negative. This case report broadens the known clinical spectrum, being the first description of post-varicella anti-SOX1 antibodies.","PeriodicalId":72572,"journal":{"name":"Child neurology open","volume":"10 ","pages":"2329048X231200613"},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c0/fc/10.1177_2329048X231200613.PMC10517599.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41164656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease and an Incidental Thyroid Nodule. 髓鞘少突胶质细胞糖蛋白抗体相关疾病和一例甲状腺结节。

Child neurology open Pub Date : 2023-09-20 eCollection Date: 2023-01-01 DOI: 10.1177/2329048X231202675

C J Henriquez, S F Ahmad

引用次数: 0

Refractory Jeavons Syndrome from Birth Symptomatic to PLCB1 Mutation. 从出生症状到 PLCB1 基因突变的难治性杰文斯综合征

Child neurology open Pub Date : 2023-07-02 eCollection Date: 2023-01-01 DOI: 10.1177/2329048X231183524

Alexandria L Spurgeon, Shannon F Keaveney, Yu-Tze Ng

引用次数: 0

Be in the Digital Room Where it Happens, Part II: Social Media for Neurology Educators. 置身于数字世界，第二部分：神经病学教育工作者的社交媒体。

Child neurology open Pub Date : 2023-04-20 eCollection Date: 2023-01-01 DOI: 10.1177/2329048X231169400

Jessica Goldstein, Jaclyn M Martindale, Catherine Albin, Kathryn Xixis, Rachel Gottlieb-Smith, Scott Otallah, Arpita Lakhotia, Lauren D Strauss, Nancy Bass, Roy E Strowd, Adam Rodman

{"title":"Be in the Digital Room Where it Happens, Part II: Social Media for Neurology Educators.","authors":"Jessica Goldstein, Jaclyn M Martindale, Catherine Albin, Kathryn Xixis, Rachel Gottlieb-Smith, Scott Otallah, Arpita Lakhotia, Lauren D Strauss, Nancy Bass, Roy E Strowd, Adam Rodman","doi":"10.1177/2329048X231169400","DOIUrl":"10.1177/2329048X231169400","url":null,"abstract":"Social media has changed the way we communicate and interact. Unsurprisingly, it has also changed how we teach and learn. Younger generations of learners have transitioned from traditional educational sources to digital ones. Medical educators need to adapt to trends in medical education and develop fluency in the digital methods used by medical learners today. This is part two of a two-part series on social media and digital education in neurology. This article provides an overview of how social media can be used as a teaching tool in medical education and provides an overview in which it is grounded. We offer practical strategies on how social media can promote lifelong learning, educator development, educator support, and foster educator identity with accompanying neurology-specific examples. We also review considerations for incorporating social media into teaching and learning practices and future directions for integrating these tools in neurology education.","PeriodicalId":72572,"journal":{"name":"Child neurology open","volume":"10 ","pages":"2329048X231169400"},"PeriodicalIF":0.0,"publicationDate":"2023-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/83/c2/10.1177_2329048X231169400.PMC10126786.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9733705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Progressive Flaccid Paraplegia in a Toddler due to Chiari Type I Malformation Complicated with Hydrocephalus and Syringomyelia. A Case Report. 由于Chiari I型畸形并发脑积水和脊髓空洞导致的幼儿进行性弛缓性截瘫。一个病例报告。

Child neurology open Pub Date : 2023-01-01 DOI: 10.1177/2329048X231169510

Angelina Lo, Megan C LaRocca, Danielle Whalen, Zurisadai Gonzalez-Castillo

引用次数: 0

Rhythmic mid-Temporal Theta of Drowsiness Activated by Hyperventilation- Uncommon Trigger of a Rare Benign EEG Variant in Pediatrics. An Educational Review. 过度换气激活的嗜睡节律性颞中θ波——儿科罕见良性脑电图变异的罕见触发因素。教育评论。

Child neurology open Pub Date : 2023-01-01 DOI: 10.1177/2329048X231153506

Brooke Asemota, Jacob M Dohmeier, Nupur Singh, Andrew J Gienapp, Marianna Rivas-Coppola, Nitish Chourasia

引用次数: 0

A 2-Year-Old Child with Alazami Syndrome with Newly Reported Findings of Immune Deficiency, Periventricular Nodular Heterotopia, and Stroke; Broadening the Phenotype of Alazami. 2岁Alazami综合征患儿伴免疫缺陷、脑室周围结节性异位和脑卒中Alazami表型的拓宽。

Child neurology open Pub Date : 2023-01-01 DOI: 10.1177/2329048X231190784

Kristin D Fauntleroy-Love, Theodore E Wilson, Nurcicek Padem, Meredith R Golomb

{"title":"A 2-Year-Old Child with Alazami Syndrome with Newly Reported Findings of Immune Deficiency, Periventricular Nodular Heterotopia, and Stroke; Broadening the Phenotype of Alazami.","authors":"Kristin D Fauntleroy-Love, Theodore E Wilson, Nurcicek Padem, Meredith R Golomb","doi":"10.1177/2329048X231190784","DOIUrl":"https://doi.org/10.1177/2329048X231190784","url":null,"abstract":"Alazami syndrome is a rare autosomal recessive neurodevelopmental disorder due to loss-of-function variants in the La ribonucleoprotein 7 (LARP7) gene. Children with Alazami syndrome are most often affected by a combination of primordial dwarfism, intellectual disability, and distinctive facial features. Previous cases have been primarily found in consanguineous families from the Middle East, Asia, and North Africa. We present a 21-month-old Caucasian male from the Midwest United States with nonconsanguineous parents who presented with frequently reported findings of unusual facial features, poor growth, cardiac and genitourinary findings, and developmental delay; less-frequently reported findings, including transient erythroblastopenia of childhood (TEC) and immune deficiency; and never-before reported findings of periventricular nodular heterotopia and stroke. He developed stroke during a hospitalization for Hemophilus influenzae meningitis. The possible contributions of LARP7 to TEC, immune deficiency, brain malformation, and stroke are discussed. Guidelines for the care of Alazami patients are proposed.","PeriodicalId":72572,"journal":{"name":"Child neurology open","volume":"10 ","pages":"2329048X231190784"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/fa/3d/10.1177_2329048X231190784.PMC10388622.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10666606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tacrolimus Induced Leukoencephalopathy and Stroke-Like Symptoms: Case Report. 他克莫司致脑白质病和卒中样症状:1例报告。

Child neurology open Pub Date : 2023-01-01 DOI: 10.1177/2329048X231171011

Kelly M Dopke, Nader El Seblani, Katherine Mercer, Sunil Naik, Gayatra Mainali, Dustin Paul

引用次数: 0

Methods for Detecting Abnormal Ventilation in Children - the Case Study of 13-Years old Pitt-Hopkins Girl. 儿童异常通气的检测方法——以13岁Pitt-Hopkins女孩为例。

Child neurology open Pub Date : 2023-01-01 DOI: 10.1177/2329048X231151361

Pekka Nokelainen, Jose-Maria Perez-Macias, Sari-Leena Himanen, Anna Hakala, Mirja Tenhunen

{"title":"Methods for Detecting Abnormal Ventilation in Children - the Case Study of 13-Years old Pitt-Hopkins Girl.","authors":"Pekka Nokelainen, Jose-Maria Perez-Macias, Sari-Leena Himanen, Anna Hakala, Mirja Tenhunen","doi":"10.1177/2329048X231151361","DOIUrl":"https://doi.org/10.1177/2329048X231151361","url":null,"abstract":"We present contactless technology measuring abnormal ventilation and compare it with polysomnography (PSG). A 13-years old girl with Pitt-Hopkins syndrome presented hyperpnoea periods with apneic spells. The PSG was conducted simultaneously with Emfit movement sensor (Emfit, Finland) and video camera with depth sensor (NEL, Finland). The respiratory efforts from PSG, Emfit sensor, and NEL were compared. In addition, we measured daytime breathing with tracheal microphone (PneaVox,France). The aim was to deepen the knowledge of daytime hyperpnoea periods and ensure that no upper airway obstruction was present during sleep. The signs of upper airway obstruction were not detected despite of minor sleep time. Monitoring respiratory effort with PSG is demanding in all patient groups. The used unobtrusive methods were capable to reveal breathing frequency and hyperpnoea periods. Every day diagnostics need technology like this for monitoring vital signs at hospital wards and at home from subjects with disabilities and co-operation difficulties.","PeriodicalId":72572,"journal":{"name":"Child neurology open","volume":"10 ","pages":"2329048X231151361"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9944179/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10789197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Efficacy of Melatonin for Inducing Sleep in Pediatric Electroencephalogram Recordings: A Single-Blind Randomized Controlled Pilot Study. 褪黑素在儿童脑电图记录中诱导睡眠的功效:一项单盲随机对照先导研究。

Child neurology open Pub Date : 2023-01-01 DOI: 10.1177/2329048X231194251

Kornkamol Holsakul, Sathida Poonmaksatit, Pariyapa Thiamrakij, Montida Veeravigrom

{"title":"Efficacy of Melatonin for Inducing Sleep in Pediatric Electroencephalogram Recordings: A Single-Blind Randomized Controlled Pilot Study.","authors":"Kornkamol Holsakul, Sathida Poonmaksatit, Pariyapa Thiamrakij, Montida Veeravigrom","doi":"10.1177/2329048X231194251","DOIUrl":"https://doi.org/10.1177/2329048X231194251","url":null,"abstract":"Objective To compare the efficacy of melatonin, melatonin with sleep deprivation, and chloral hydrate with sleep deprivation on sleep induction in Asian children. Methods: For this randomized single-blind controlled trial, we recruited 45 children aged 1-5 years and older who were not cooperative on electroencephalogram (EEG) recordings, randomly allocated to three groups: melatonin (group A), melatonin and sleep deprivation (group B), or chloral hydrate and sleep deprivation (group C). Between-group comparisons were performed using the Kruskal-Wallis and Mann-Whitney U tests. Results: Stage II sleep was achieved in 92.8%, 100%, and 100% of participants in groups A, B, and C, respectively. Sleep latency was significantly shorter in Group C than in Groups A (p = .022) and B (p = .027), while Group C had better sleep efficacy than Groups A (p = .02) and B (p = .04). Conclusion: Melatonin with sleep deprivation is less effective at inducing sleep than combined chloralhydrate and sleep deprivation.","PeriodicalId":72572,"journal":{"name":"Child neurology open","volume":"10 ","pages":"2329048X231194251"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c6/22/10.1177_2329048X231194251.PMC10424547.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10355825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0