Acta tropica最新文献

{"title":"Respiratory pathogens carriage in guinea pigs raised as livestock in Ecuador: A proxy to study a neglected reservoir for zoonotic transmission in the Andean Region","authors":"Angel Sebastian Rodriguez-Pazmiño ,&nbsp;Marlon Zambrano-Mila ,&nbsp;Mauricio Salas-Rueda ,&nbsp;Marco Vinicio Cáceres-Orellana ,&nbsp;Dayci Buele-Chica ,&nbsp;Lenay Barrera-Barroso ,&nbsp;Ismar Rivera-Olivero ,&nbsp;Washington Bolivar Cardenas ,&nbsp;Solon Alberto Orlando ,&nbsp;Henry Parra-Vera ,&nbsp;Miguel Angel Garcia-Bereguiain","doi":"10.1016/j.actatropica.2024.107505","DOIUrl":"10.1016/j.actatropica.2024.107505","url":null,"abstract":"<div><div>In the Andean region of South America, guinea pigs (<em>Cavia porcellus</em>) are raised as livestock in close contact with other domestic animals and humans. Although the susceptibility of guinea pigs to being affected by a wide range of diseases is well known as a laboratory animal model, there are a few reports about the potential role of zoonotic pathogens in livestock guinea pigs. In this work, we analyzed the nasopharyngeal carriage of respiratory pathogenic viruses and bacteria in guinea pigs from farms in Ecuador. We isolated streptococci and aerococci cultures that were analyzed for species identification by MALDI-TOF MS. Several species, including <em>Streptococcus pneumoniae, S. pseudopneumoniae, S. oralies,</em> and <em>S. mitis</em> were found. Moreover, strains resistant to antibiotics like <em>levofloxacin, erythromycin,</em> and <em>sulfamethoxazole-trimethoprim</em> were also found<em>.</em> Our results suggest the role of guinea pigs as a zoonotic reservoir for occupational exposure to respiratory pathogens in the Andean region of South America, where guinea pig farming is an important industry.</div></div>","PeriodicalId":7240,"journal":{"name":"Acta tropica","volume":"261 ","pages":"Article 107505"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142833493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hantavirus Pulmonary Syndrome in Northwestern Argentina: Seroprevalence in rodents of Jujuy province and first seropositive record for Euryoryzomys legatus","authors":"F. Cassinelli ,&nbsp;W. López ,&nbsp;R. Coelho ,&nbsp;J.J. Martínez ,&nbsp;S. Kehl ,&nbsp;C.M. Bellomo ,&nbsp;V.P. Martínez ,&nbsp;I. Ferro","doi":"10.1016/j.actatropica.2024.107500","DOIUrl":"10.1016/j.actatropica.2024.107500","url":null,"abstract":"<div><div>Hantavirus Pulmonary Syndrome (HPS) is a Pan-American emerging infectious disease with a high mortality rate caused by rodent-borne viruses of the genus <em>Orthohantavirus</em>. In Argentina, almost half of the HPS infections occur in the northwestern endemic region. In this study, we evaluated rodent composition, abundance, and antibody prevalence in wild rodents in three subtropical sites: primary forest, secondary forest, and crop fields. From February 2022 to June 2023, we settled a total of 150 traps for three nights every two months reaching a capture-effort of 5,400 trap-nights. We took blood samples from all captured rodents, registered morphological measures, then marked and released. We captured 103 rodents of 5 species (<em>Oligoryzomys chacoensis, Calomys fecundus, Calomys musculinus, Akodon simulator</em>, and <em>Euryoryzomys legatus).</em> The overall antibody prevalence was 10.18 %; with <em>C. fecundus</em> and <em>A. simulator</em> being the species most frequently found to present antibodies, and they were also the dominant species in the captured rodent community. The secondary forest was, by far, the most productive site with 83.5 % of all captures, followed by crop fields (10.68 %) and primary forest (5.82 %). We found that antibody prevalence for <em>C. fecundus</em> was positively correlated to body mass (weight) and size (total length). Another important result of our work is that we report presence of hantavirus antibodies in <em>E. legatus,</em> which represents the first record for this species. These results highlight the importance of continuous monitoring of rodents populations and provide a framework for the planning and implementation of public health prevention campaigns of field workers.</div></div>","PeriodicalId":7240,"journal":{"name":"Acta tropica","volume":"261 ","pages":"Article 107500"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142870968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Climatic and meteorological factors shaping the potential activity season of sand flies in Southeast Europe","authors":"Attila J. Trájer ,&nbsp;Edwin Kniha","doi":"10.1016/j.actatropica.2024.107486","DOIUrl":"10.1016/j.actatropica.2024.107486","url":null,"abstract":"<div><div>Sand flies, the principal vectors of <em>Leishmania</em> spp., are widely endemic in the Balkans and its neighbouring area. Among many factors, meteorological constraints shape sand fly distribution and activity, and are therefore important to assess to understand sand fly occurrence and prevent transmission of pathogens. To determine the daily limits of sand fly activity in Southeast Europe, we used entomological trapping data of eight species from seven countries, as well as temperature, precipitation, global radiation, wind speed, and sea level pressure data of the E-OBS gridded dataset. While 91.3 % of analyzed sites represented humid subtropical-continental ecotypes, heterogenous meteorological activity thresholds were found between species. By ranking the species based on their meteorological limits, <em>Phlebotomus balcanicus</em> and <em>Ph. papatasi</em> showed the widest general meteorological tolerance, whereas the activity of <em>Sergentomyia minuta, Ph. tobbi</em>, and <em>Ph. simici</em> were observed to be most sensitive to meteorological changes. However, principal ordinate analysis suggested that <em>Ph. neglectus</em> and <em>Ph. mascittii</em> had the widest ecological niches related to their activity constraints, and <em>Ph. tobbi</em> and <em>Ph. simici</em> had the narrowest. <em>Phlebotomus mascitti</em> and <em>Se. minuta</em> exhibited the most notable overall dissimilarity of the meteorological requirements of activity. The ensemble tests showed that the feature importance of different meteorological factors varies by sand fly species related to their activity. This study should help to better understand small-scale differences in sand fly occurrence in Southeast Europe to support future surveys and targeted surveillance to assess pathogen transmission in endemic areas.</div></div>","PeriodicalId":7240,"journal":{"name":"Acta tropica","volume":"261 ","pages":"Article 107486"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142765440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Innate and putative adaptive immunological responses of schistosome-parasitized snails","authors":"Khaled M. Zayed","doi":"10.1016/j.actatropica.2024.107503","DOIUrl":"10.1016/j.actatropica.2024.107503","url":null,"abstract":"<div><div>Schistosomiasis is a neglected tropical disease caused by digenetic trematode from Schistosoma genus, as an etiological agent that uses snails as an intermediate host. In mollusc-trematode relationships, the miracidia attract in the aquatic media to a specific snail as an intermediate hosts, then penetrate its integument in the sporocyst form thereafter, the invasive sporocysts produce secreted/excreted products in order to survive and avoid the snails’ immune system. The next larval stage is the cercariae that developed by sporocysts. Subsequently, the snail intermediate host suffers from biological, physiological, biochemical and immunological changes during the development of these parasite larval stages within their tissues. Snails and their parasites engage in an interactive innate and putative adaptive immune response that involves many immune mechanisms, such as the production of nitric oxide, lysozymes, phagocytosis, lectin formation and phenol oxidase activity. Schistosomes have developed a variety of strategies to evade and counteract these deliberate host reactions. These strategies include the secretion of many strong proteases, the use of an immune-resistant outer tegument, the molecular mimicry of host antigens, and the controlled release of certain immunomodulatory substances that influence immune cell activities. This review aims to characterize these important immune evasion mechanisms in order to comprehend the many immunological molecular determinants in the snail/schistosome interaction and to develop alternate management measures for schistosomiasis control.</div></div>","PeriodicalId":7240,"journal":{"name":"Acta tropica","volume":"261 ","pages":"Article 107503"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142827206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unusual frequency of Trypanosoma cruzi DTU TcI and predominance of hybrid lineages in Triatoma infestans before and after control interventions in the Argentinian Chaco","authors":"Alejandra Alvedro ,&nbsp;Natalia Paula Macchiaverna ,&nbsp;Niamh Murphy ,&nbsp;Gustavo Fabián Enriquez ,&nbsp;María Sol Gaspe ,&nbsp;Ricardo Esteban Gürtler ,&nbsp;Marta Victoria Cardinal","doi":"10.1016/j.actatropica.2024.107502","DOIUrl":"10.1016/j.actatropica.2024.107502","url":null,"abstract":"<div><div>Transmission of <em>Trypanosoma cruzi</em> involves diverse hosts, vectors and parasitic genotypes, in different environments. In recent decades, the distribution of <em>T. cruzi</em> has altered due to urbanization of affected people and vectors. We implemented a longitudinal intervention program between 2015 and 2022 which aimed to suppress (<em>peri</em>)domestic <em>Triatoma infestans</em> in the municipality of Avia Terai (Chaco Province, Argentina), and found a marginal risk of domestic vector-borne transmission across the rural-to-urban gradient after interventions. Here, we identified the parasite Discrete Typing Units (DTUs) in infected <em>T. infestans</em> collected throughout the intervention program (37 insects pre-intervention and 7 post-intervention). Identification of DTUs was conducted by two methodologies, using DNA extracted from <em>T. infestans</em> rectal ampoules. We also assessed the association between blood-feeding sources and DTUs. Complete DTU identification was achieved in 48 % of samples. The hybrid lineages TcV or TcVI and their combinations predominated (72 %), followed by TcI (16 %) and mixed infections of TcI and hybrid lineages (14 %). Half (50 %) of the houses harbored TcI infected bugs either alone or mixed with TcII/TcV/TcVI. Humans predominated as the bloodmeal sources in all insects with identified DTU. All DTUs (TcI, TcV and TcII/TcV/TcVI) were recorded in both rural and peri-urban environments, with 62 % of the houses having more than one DTU. These results confirm the predominance of hybrid lineages in domestic transmission cycles of the Argentine Chaco. However, the finding of several triatomines infected with TcI both pre- and post-intervention raises the question of which host(s) are involved in its transmission.</div></div>","PeriodicalId":7240,"journal":{"name":"Acta tropica","volume":"261 ","pages":"Article 107502"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142827207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Identification and characterization of Jingmen tick virus from Rhipicephalus microplus in Hunan, China” [Acta Tropica 260 (2024) 107378]","authors":"Li Zhang ,&nbsp;Wenbo Xu ,&nbsp;Yinghua Zhao ,&nbsp;Liyan Sui ,&nbsp;Mingxin Song ,&nbsp;Quan Liu","doi":"10.1016/j.actatropica.2024.107443","DOIUrl":"10.1016/j.actatropica.2024.107443","url":null,"abstract":"","PeriodicalId":7240,"journal":{"name":"Acta tropica","volume":"260 ","pages":"Article 107443"},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142611943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Establishment of a programmatic detection method for Trichomonas vaginalis based on double antibody sandwich ELISA targeting TvCP39 antigen","authors":"Yuhua Li ,&nbsp;Fakun Li ,&nbsp;Wenjie Tian ,&nbsp;Yani Zhang ,&nbsp;Weijuan Wang ,&nbsp;Zhenke Yang ,&nbsp;Xiaowei Tian ,&nbsp;Shuai Wang ,&nbsp;Xuefang Mei ,&nbsp;Zhenchao Zhang","doi":"10.1016/j.actatropica.2024.107489","DOIUrl":"10.1016/j.actatropica.2024.107489","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;div&gt;&lt;em&gt;Trichomonas vaginalis&lt;/em&gt; (&lt;em&gt;T. vaginalis&lt;/em&gt;) is a common sexually transmitted parasite that colonizes the human urogenital tract. Programmed and precise detection of &lt;em&gt;T. vaginalis&lt;/em&gt; is a key step in preventing and treating trichomoniasis. However, the current detection methods of &lt;em&gt;T. vaginalis&lt;/em&gt;, including wet mount microscopy, culture, nested PCR, loop-mediated isothermal amplification, and recombinant enzyme polymerase amplification, have some shortcomings. Therefore, it is urgent to establish a programmed, sensitive, and specific method for detecting &lt;em&gt;T. vaginalis&lt;/em&gt;.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;&lt;em&gt;T. vaginalis&lt;/em&gt; cysteine protease 39 (TvCP39) was expressed in segments as TvCP39–1 and TvCP39–2, and the polyclonal antibodies were prepared by immunizing rats and rabbits. The concentration of the polyclonal antibodies of anti-rTvCP39–2 and anti-rTvCP39–1 was determined by square matrix titration. The sensitivity and specificity of double antibody sandwich ELISA were analyzed and evaluated by detecting rTvCP39 and &lt;em&gt;T. vaginalis&lt;/em&gt; excretory-secretory proteins (TvESPs) diluted in multiple ratios and detecting excretory-secretory proteins of &lt;em&gt;T. vaginalis&lt;/em&gt; and other pathogens, respectively. The detection efficiency of wet mount microscopy, nested PCR, and double antibody sandwich ELISA was compared by testing sixty-two clinical samples from vaginal secretions.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;The natural TvCP39 protein could be specifically recognized by anti-rTvCP39–1 and anti-rTvCP39–2 antibodies. The concentrations of anti-rTvCP39–2 and anti-rTvCP39–1 polyclonal antibodies were determined to be 0.58 μg/mL and 0.45 μg/mL, respectively. The results of the sensitivity test showed that the detection limits of rTvCP39 and TvESPs by double antibody sandwich ELISA were 1.76 ng/mL and 107.125 μg/mL, respectively. The specificity test results showed that the double antibody sandwich ELISA had a high specificity for the detection of &lt;em&gt;T. vaginalis&lt;/em&gt; and did not cross-react with &lt;em&gt;Escherichia coli, Staphylococcus aureus, Candida albicans&lt;/em&gt;, and &lt;em&gt;Lactobacillus&lt;/em&gt;. The positive detection rate of clinical samples by double antibody sandwich ELISA was higher than that by wet mount microscopy, and was the same as nested PCR. The sensitivity of double antibody sandwich ELISA was consistent with that of nested PCR. The coincidence rate between double antibody sandwich ELISA and nested PCR was 100% (&lt;em&gt;Kappa&lt;/em&gt;=1, &lt;em&gt;P&lt;/em&gt; &lt; 0.001).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusion&lt;/h3&gt;&lt;div&gt;The double antibody sandwich ELISA detection method for &lt;em&gt;T. vaginalis&lt;/em&gt; established in this study had the advantages of high sensitivity and specificity, and did not require the extraction of genomic DNA. This programmatic and simple detection method was suitable for batch testing of clinical samples and exhibited the potential value in the treatment and prevention of trichomoniasis.&lt;/d","PeriodicalId":7240,"journal":{"name":"Acta tropica","volume":"260 ","pages":"Article 107489"},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142765444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Repellent activity of icaridin-impregnated horsecloth against horse flies","authors":"Keisuke Suganuma ,&nbsp;Go Fujita ,&nbsp;Adrian Miki C. Macalanda ,&nbsp;Maria Angenica F. Regilme ,&nbsp;Hiroshi Izumida ,&nbsp;Noboru Inoue ,&nbsp;Tomas J. Acosta","doi":"10.1016/j.actatropica.2024.107485","DOIUrl":"10.1016/j.actatropica.2024.107485","url":null,"abstract":"<div><div>Horseflies are pests that cause discomfort from blood-sucking and disease transmission, and economic losses in the equine industry. This study evaluated the efficacy of horsecloth impregnated with icaridin in reducing horsefly attacks and deterring horseflies. Repellent activities were evaluated under three conditions: treatment 1 (no horsecloth), 2 (horsecloth without icaridin), and 3 (horsecloth impregnated with icaridin), using three native Hokkaido horses (Dosanko) and three mixed-breed horses (Dosanko and Haflinger) in July 2023 at a riding horse club in Hokkaido, Japan. Treatment 3 significantly reduced the number of horseflies. Treatment 2 did not significantly reduce horsefly numbers. Treatments 2 and 3 significantly reduced the number of avoidance actions. The reduction in avoidance actions in treatment 3 was greater than that in treatment 2. Lighter-colored horses experienced fewer fly attacks and avoidance actions than darker-colored horses. Overall, using icaridin-impregnated horsecloths (treatment 3) was more effective for repelling horseflies than the use of physical barriers alone (treatment 2). This study suggests that integrating chemical repellents with physical protection can enhance horsefly control strategies, improve horse welfare, and improve the safety of horses interacting with them. Further research is recommended to assess the generalizability of these findings to different horse breeds and environments with a greater number of horses.</div></div>","PeriodicalId":7240,"journal":{"name":"Acta tropica","volume":"260 ","pages":"Article 107485"},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142743047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New Techniques and Tools for Mosquito Control","authors":"Rui-De Xue,&nbsp;Tong-Yan Zhao,&nbsp;Chun-Xiao Li","doi":"10.1016/j.actatropica.2024.107425","DOIUrl":"10.1016/j.actatropica.2024.107425","url":null,"abstract":"","PeriodicalId":7240,"journal":{"name":"Acta tropica","volume":"260 ","pages":"Article 107425"},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142399094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evidence of endogenous non-retroviral RNA virus sequences into the genome and transcriptome of the malaria vector Anopheles darlingi","authors":"Juan C. Hernandez-Valencia ,&nbsp;Paola Muñoz-Laiton ,&nbsp;Giovan F. Gómez ,&nbsp;Margarita M. Correa","doi":"10.1016/j.actatropica.2024.107469","DOIUrl":"10.1016/j.actatropica.2024.107469","url":null,"abstract":"<div><div>The characterization of non-retroviral integrated RNA virus sequences (NIRVS) in mosquitoes has emerged as a significant area of research that could yield insight into virus-host interactions. This study aimed to characterize NIRVS in the <em>Anopheles darlingi</em> reference genome and identify putative transcribed NIRVS in field-collected mosquitoes from Colombia. The <em>An. darlingi</em> reference genome was analyzed to identify and characterize NIRVS by conducting a BLAST query with all the virus sequences previously identified in arthropods available in the NCBI-virus repository. In addition, <em>An. darlingi</em> field-collected mosquitoes were examined for NIRVS using a metatranscriptomic approach. As a result, 44 NIRVS were identified in the <em>An. darlingi</em> genome, constituting integrations of negative single-stranded RNA viruses (ssRNA-) from the families <em>Rhabdoviridae, Chuviridae</em> and <em>Phasmaviridae</em>, and integrations of double-stranded RNA viruses (dsRNA) from the families <em>Partitiviridae</em> and <em>Sedoreoviridae</em>. These NIRVS were not randomly distributed but clustered in specific regions of the genome enriched with BEL/Pao and Ty3/Gypsy long terminal repeat elements. Furthermore, putative NIRVS-like sequences were present in the transcriptomic data from all the Colombian <em>An. darlingi</em> natural populations. This study is significant as it represents the first identification of NIRVS in the most important malaria vector of the Neotropics. The findings help in understanding the intricate relationship between the mosquito and its virome, and the regulation of viruses’ mechanisms in the <em>Anopheles</em> genus.</div></div>","PeriodicalId":7240,"journal":{"name":"Acta tropica","volume":"260 ","pages":"Article 107469"},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142643686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}