AsiaInterventionPub Date : 2023-09-21eCollection Date: 2023-09-01DOI: 10.4244/AIJ-D-22-00089
Adrienne Yh Chew, Chi-Hang Lee
{"title":"Obstructive sleep apnoea and coronary revascularisation outcomes.","authors":"Adrienne Yh Chew, Chi-Hang Lee","doi":"10.4244/AIJ-D-22-00089","DOIUrl":"10.4244/AIJ-D-22-00089","url":null,"abstract":"<p><p>Obstructive sleep apnoea (OSA) is a chronic sleep disorder characterised by recurrent cyclical episodes of upper airway collapse causing apnoea or hypopnoea. Despite being highly prevalent in patients with cardiovascular conditions, OSA has been a neglected component in cardiovascular practice. Fortunately, in the past few decades, increasing acknowledgement of the vulnerability of cardiac patients to OSA-related stressors and its adverse cardiovascular outcomes has made it a recognised cardiovascular risk factor in practice guidelines. Consequences of OSA include oxidative stress, endothelial dysfunction, autonomic dysfunction, and increased catecholamine release. The perturbations caused by OSA not only provide a clear mechanistic link to cardiovascular disease but also to poor outcomes after coronary revascularisation. This review article focuses on the correlation of OSA to coronary revascularisation outcomes. Our team reported that OSA is present in approximately 50% of patients undergoing coronary revascularisation. Importantly, untreated OSA was found to be an independent predictor of adverse events after both percutaneous coronary intervention and coronary artery bypass grafting. Although randomised trials did not confirm the benefits of OSA treatment in improving cardiovascular outcomes, these early trials were limited by poor treatment adherence. For now, systematic screening for OSA in patients undergoing coronary revascularisation is not indicated. Yet, with the proven benefit of OSA treatment in improving blood pressure control and quality of life, screening for and treatment of OSA is still indicated if patients have reported excessive daytime sleepiness and/or suboptimally controlled hypertension.</p>","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"9 2","pages":"105-113"},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507609/pdf/AIJ-D-22-00089_Chew.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41173362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AsiaInterventionPub Date : 2023-09-21eCollection Date: 2023-09-01DOI: 10.4244/AIJ-E-23-00004
Ashok Seth
{"title":"Sharing knowledge and defining partnerships across boundaries through AICT-AsiaPCR.","authors":"Ashok Seth","doi":"10.4244/AIJ-E-23-00004","DOIUrl":"https://doi.org/10.4244/AIJ-E-23-00004","url":null,"abstract":"","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"9 2","pages":"97-98"},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507599/pdf/AIJ-E-23-00004_Seth.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41107336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AsiaInterventionPub Date : 2023-09-21eCollection Date: 2023-09-01DOI: 10.4244/AIJ-D-23-00014
Ramanathan Velayutham, A Shaheer Ahmed, Saurav Banerjee
{"title":"Calcification with a figure of eight appearance found in routine coronary angiography.","authors":"Ramanathan Velayutham, A Shaheer Ahmed, Saurav Banerjee","doi":"10.4244/AIJ-D-23-00014","DOIUrl":"https://doi.org/10.4244/AIJ-D-23-00014","url":null,"abstract":"","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"9 2","pages":"170-171"},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507602/pdf/AIJ-D-23-00014_Velayutham.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41166953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AsiaInterventionPub Date : 2023-09-21eCollection Date: 2023-09-01DOI: 10.4244/AIJ-D-22-00051
Qiuping Shi, Bin Zhang, Xingang Wang, Jintao Fei, Qiao Qin, Bo Zheng, Ming Chen
{"title":"Safety and efficacy of a novel 3D-printed bioresorbable sirolimus-eluting scaffold in a porcine model.","authors":"Qiuping Shi, Bin Zhang, Xingang Wang, Jintao Fei, Qiao Qin, Bo Zheng, Ming Chen","doi":"10.4244/AIJ-D-22-00051","DOIUrl":"https://doi.org/10.4244/AIJ-D-22-00051","url":null,"abstract":"<p><strong>Background: </strong>The effect of 3D-printed bioresorbable vascular scaffolds (BRS) in coronary heart disease has not been clarified.</p><p><strong>Aims: </strong>We aimed to compare the safety and efficacy of 3D-printed BRS with that of metallic sirolimus-eluting stents (SES).</p><p><strong>Methods: </strong>Thirty-two BRS and 32 SES were implanted into 64 porcine coronary arteries. Quantitative coronary angiography (QCA) and optical coherence tomography (OCT) were performed at 14, 28, 97, and 189 days post-implantation. Scanning electron microscopy (SEM) and histopathological analyses were performed at each assessment.</p><p><strong>Results: </strong>All stents/scaffolds were successfully implanted. All animals survived for the duration of the study. QCA showed the two devices had a similar stent/scaffold-to-artery ratio and acute percent recoil. OCT showed the lumen area (LA) and scaffold/stent area (SA) of the BRS were significantly smaller than those of the SES at 14 and 28 days post-implantation (14-day LA: BRS vs SES 4.52±0.41 mm<sup>2</sup> vs 5.69±1.11 mm<sup>2</sup>; p=0.03; 14-day SA: BRS vs SES 4.99±0.45 mm<sup>2</sup> vs 6.11±1.06 mm<sup>2</sup>; p=0.03; 28-day LA: BRS vs SES 2.93±1.03 mm<sup>2</sup> vs 4.82±0.74 mm<sup>2</sup>; p=0.003; 28-day SA: BRS vs SES 3.86±0.98 mm<sup>2</sup> vs 5.75±0.71 mm<sup>2</sup>; p=0.03). Both the LA and SA of the BRS increased over time and were similar to those of the SES at the 97-day and 189-day assessments. SEM and histomorphological analyses showed no significant between-group differences in endothelialisation at each assessment.</p><p><strong>Conclusions: </strong>The novel 3D-printed BRS showed safety and efficacy similar to that of SES in a porcine model. The BRS also showed a long-term positive remodelling effect.</p>","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"9 2","pages":"133-142"},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507451/pdf/AIJ-D-22-00051_Shi.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41107320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical prognostic value of a novel quantitative flow ratio from a single projection in patients with coronary bifurcation lesions treated with the provisional approach.","authors":"Jing Kan, Zhen Ge, Shaoping Nie, Xiaofei Gao, Xiaobo Li, Imad Sheiban, Jun-Jie Zhang, Shao-Liang Chen","doi":"10.4244/AIJ-D-22-00045","DOIUrl":"https://doi.org/10.4244/AIJ-D-22-00045","url":null,"abstract":"<p><strong>Background: </strong>A novel quantitative flow ratio (μQFR) for bifurcated coronary vessels, derived from a single projection, has been recently reported. Provisional stenting is effective for most bifurcation lesions. However, the clinical value of the side branch (SB) μQFR in patients with coronary bifurcation lesions undergoing provisional stenting remains unclear.</p><p><strong>Aims: </strong>This study aims to determine the clinical predictive value of the SB μQFR after provisional stenting in patients with coronary bifurcation lesions.</p><p><strong>Methods: </strong>Between June 2015 and May 2018, 288 patients with true coronary bifurcation lesions who underwent a provisional approach without SB treatment (including predilation, kissing balloon inflation or stenting) were classified by an SB μQFR <0.8 (n=65) and ≥0.8 (n=223) groups. The primary endpoint was the three-year composite of target vessel failure (TVF), including cardiac death, target vessel myocardial infarction (TVMI), and revascularisation (TVR).</p><p><strong>Results: </strong>Three years after the procedures, there were 43 (14.9%) TVFs, with 19 (29.2%) in the SB μQFR <0.8 and 24 (10.8%) in the SB μQFR ≥0.8 groups (adjusted hazard ratio [HR] 2.45, 95% confidence interval [CI] 1.39-5.54; p=0.003), mainly driven by increased TVMI (16.9% vs 5.4%, adjusted HR 3.29, 95% CI: 1.15-6.09; p=0.030) and TVR (15.4% vs 2.2%, adjusted HR 6.39, 95% CI: 2.04-13.48; p=0.007). Baseline diameter stenosis at the ostial SB and SB lesion length were the two predictors of an SB μQFR <0.8 immediately after stenting the main vessel, whereas previous percutaneous coronary intervention and an SB μQFR <0.8 were the two independent factors of 3-year TVF.</p><p><strong>Conclusions: </strong>An SB μQFR <0.8 immediately after the provisional approach is strongly associated with clinical events. Further randomised studies with large patient populations are warranted.</p>","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"9 2","pages":"114-123"},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507452/pdf/AIJ-D-22-00045_Kan.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41163967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AsiaInterventionPub Date : 2023-09-21eCollection Date: 2023-09-01DOI: 10.4244/AIJ-D-22-00063
Kento Kito, Akihisa Kataoka, Hirofumi Hioki, Yusuke Watanabe, Ken Kozuma
{"title":"Paracentral MitraClip implantation technique in a mitral valve with a small area due to rheumatic change.","authors":"Kento Kito, Akihisa Kataoka, Hirofumi Hioki, Yusuke Watanabe, Ken Kozuma","doi":"10.4244/AIJ-D-22-00063","DOIUrl":"https://doi.org/10.4244/AIJ-D-22-00063","url":null,"abstract":"","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"9 2","pages":"166-167"},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507450/pdf/AIJ-D-22-00063_Kito.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41163903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}