AsiaInterventionPub Date : 2026-07-30eCollection Date: 2026-07-01DOI: 10.4244/AIJ-D-25-00045
Sanjay Kalra, Markus P Schlaich, A K Bhalla, Alan Almeida, Anuj Kapadia, Anuj Maheshwari, Banshi Saboo, Milind Nadkar, N K Soni, Prakash K Hazra, Praveen Chandra, Rajeev Menon, Rajasekhar Varada, Rakesh Bhadade, Ramesh R Dargad, Sanjay Agarwal, Sharad Sheth, Sanjeevi Nathamuni Narasingan, Jothydev Kesavadev
{"title":"Renal denervation triage tool: a practical approach to the management of resistant hypertension.","authors":"Sanjay Kalra, Markus P Schlaich, A K Bhalla, Alan Almeida, Anuj Kapadia, Anuj Maheshwari, Banshi Saboo, Milind Nadkar, N K Soni, Prakash K Hazra, Praveen Chandra, Rajeev Menon, Rajasekhar Varada, Rakesh Bhadade, Ramesh R Dargad, Sanjay Agarwal, Sharad Sheth, Sanjeevi Nathamuni Narasingan, Jothydev Kesavadev","doi":"10.4244/AIJ-D-25-00045","DOIUrl":"10.4244/AIJ-D-25-00045","url":null,"abstract":"<p><p>Despite the availability of medications and advocacy for lifestyle interventions, over half of individuals with hypertension do not achieve recommended treatment goals owing to limitations with medications, such as high cost, side effects, and poor adherence. Renal denervation (RDN), a minimally invasive endovascular procedure targeting sympathetic nerves near the renal arteries, is gaining recognition as a safe and effective adjunctive therapy for blood pressure control in resistant hypertension, supported by several clinical trials and meta-analyses. Recognising the clinical complexity of resistant hypertension, a group of hypertension experts from India convened to develop an \"RDN triage tool\" to guide clinicians in selecting appropriate candidates for RDN therapy based on demographics, blood pressure, renal function, and cardiac status. This approach is supported by clinical evidence and expert recommendations and aims to optimise patient selection for RDN therapy, aid clinical decision-making, minimise risks, and enhance patient outcomes.</p>","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"12 2","pages":"e107-e114"},"PeriodicalIF":0.0,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13397416/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148586221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AsiaInterventionPub Date : 2026-07-30eCollection Date: 2026-07-01DOI: 10.4244/AIJ-D-25-00046
Valerie Josephine Dirjayanto, Agus Tini Sridevi, Nathaniel Gilbert Dyson, Tan Huay Cheem
{"title":"Intravascular lithotripsy for coronary chronic total occlusion: a meta-analysis of procedural and clinical outcomes.","authors":"Valerie Josephine Dirjayanto, Agus Tini Sridevi, Nathaniel Gilbert Dyson, Tan Huay Cheem","doi":"10.4244/AIJ-D-25-00046","DOIUrl":"10.4244/AIJ-D-25-00046","url":null,"abstract":"<p><strong>Background: </strong>A significant gap exists within current guidelines for the treatment of chronic total occlusion (CTO), which has yielded poor prognostic outcomes. Intravascular lithotripsy (IVL) has emerged as a novel strategy implemented during percutaneous coronary intervention (PCI), but evidence to support its use is limited.</p><p><strong>Aims: </strong>We aimed to review the outcomes of IVL for CTO PCI.</p><p><strong>Methods: </strong>Databases including PubMed, Cochrane, Scopus, EBSCOhost, and ProQuest were searched for studies implementing IVL for CTO PCI. The quality of studies was assessed using the Cochrane Risk Of Bias In Non-randomized Studies of Interventions and JBI tools. An inverse variance, random-effects meta-analysis was conducted in RStudio version 2023.03.0+386 yielding pooled proportions and means along with their 95% confidence intervals (CIs). Where applicable, sensitivity and subgroup analyses were performed.</p><p><strong>Results: </strong>Five studies with 611 patients were included. Technical success was achieved in 97% (95% CI: 94-100%; I²=18%) of cases. Procedural success was achieved in 94% (95% CI: 90-97%; I²=27%), and the subgroup with a Japanese CTO score >2.8 yielded a significantly higher success rate (95% [95% CI: 93-97%] vs 91% [95% CI: 85-96%]; p=0.04). Major adverse cardiovascular events (MACE) occurred in 3% (95% CI: 2-5%; I²=0%) of cases within the in-hospital follow-up subgroup and in 6% (95% CI: 1-12%; I²=0%) of cases within the discharge follow-up subgroup. Mortality occurred in 1% (95% CI: 0-4%; I²=55%) of cases within the in-hospital subgroup and 0% (95% CI: 0-52%) of cases within the discharge subgroup. Perforation as a complication occurred in 5% (95% CI: 1-9%; I²=54%) of cases. The pooled mean procedural time was 122.94 minutes (95% CI: 102.24-143.64 minutes; I²=90%), and the mean contrast volume used was 154 mL (95% CI: 140.84-167.16 mL; I²=69%).</p><p><strong>Conclusions: </strong>IVL yielded high technical and procedural success, and comparable procedural times and contrast volume in CTO PCI. MACE, mortality, and perforation occurred in small proportions of patients. Further studies are needed to strengthen evidence and explore which subtype of CTO would benefit most from IVL.</p>","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"12 2","pages":"e125-e135"},"PeriodicalIF":0.0,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13397424/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148586190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AsiaInterventionPub Date : 2026-07-30eCollection Date: 2026-07-01DOI: 10.4244/AIJ-D-25-00092
Atsuya Tanaka, Takahiro Tokuda, Yasuhiro Oba
{"title":"Acute limb ischaemia five years after iliac covered stent placement due to protruding calcification.","authors":"Atsuya Tanaka, Takahiro Tokuda, Yasuhiro Oba","doi":"10.4244/AIJ-D-25-00092","DOIUrl":"10.4244/AIJ-D-25-00092","url":null,"abstract":"","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"12 2","pages":"e162-e163"},"PeriodicalIF":0.0,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13397419/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148586236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AsiaInterventionPub Date : 2026-07-30eCollection Date: 2026-07-01DOI: 10.4244/AIJ-D-25-00060
Yuto Abe, Yui Takaiwa, Hidetaka Nishina
{"title":"Progression of minor coronary dissection post-stenting to type A aortic dissection.","authors":"Yuto Abe, Yui Takaiwa, Hidetaka Nishina","doi":"10.4244/AIJ-D-25-00060","DOIUrl":"10.4244/AIJ-D-25-00060","url":null,"abstract":"","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"12 2","pages":"e158-e159"},"PeriodicalIF":0.0,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13440517/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148681412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AsiaInterventionPub Date : 2026-07-30eCollection Date: 2026-07-01DOI: 10.4244/AIJ-D-25-00065
Milind S Phadke, Saurabh V Limaye, Sriram Easwaran, Siddhant Yadav, Pratap J Nathani
{"title":"Retrieval of an entrapped coronary balloon with a novel buddy balloon push-and-pull technique.","authors":"Milind S Phadke, Saurabh V Limaye, Sriram Easwaran, Siddhant Yadav, Pratap J Nathani","doi":"10.4244/AIJ-D-25-00065","DOIUrl":"10.4244/AIJ-D-25-00065","url":null,"abstract":"","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"12 2","pages":"e156-e157"},"PeriodicalIF":0.0,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13397420/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148586184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AsiaInterventionPub Date : 2026-07-30eCollection Date: 2026-07-01DOI: 10.4244/AIJ-D-26-00041
Rajesh Vijayvergiya, Anirudh Mukherjee
{"title":"Intravascular lithotripsy in chronic total occlusion PCI: expanding the calcium modification armamentarium with cautious optimism.","authors":"Rajesh Vijayvergiya, Anirudh Mukherjee","doi":"10.4244/AIJ-D-26-00041","DOIUrl":"10.4244/AIJ-D-26-00041","url":null,"abstract":"","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"12 2","pages":"e101-e103"},"PeriodicalIF":0.0,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13397415/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148586198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AsiaInterventionPub Date : 2026-07-30eCollection Date: 2026-07-01DOI: 10.4244/AIJ-D-25-00072
Gulbadin Mufti, A Shaheer Ahmed
{"title":"A unique morphology of the left anterior descending artery arising from the right coronary sinus.","authors":"Gulbadin Mufti, A Shaheer Ahmed","doi":"10.4244/AIJ-D-25-00072","DOIUrl":"10.4244/AIJ-D-25-00072","url":null,"abstract":"","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"12 2","pages":"e166-e167"},"PeriodicalIF":0.0,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13440477/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148681326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AsiaInterventionPub Date : 2026-07-30eCollection Date: 2026-07-01DOI: 10.4244/AIJ-D-25-00091
Marco Zuin, Alan Fong, Giuseppe Marchese, Andrea Bertolini, Emanuele Rigatelli, Marco Foroni, Gianluca Rigatelli
{"title":"Haemodynamic predictors of lesion progression in non-ischaemic tandem coronary stenoses.","authors":"Marco Zuin, Alan Fong, Giuseppe Marchese, Andrea Bertolini, Emanuele Rigatelli, Marco Foroni, Gianluca Rigatelli","doi":"10.4244/AIJ-D-25-00091","DOIUrl":"10.4244/AIJ-D-25-00091","url":null,"abstract":"<p><strong>Background: </strong>Tandem coronary stenoses pose diagnostic challenges due to complex flow interactions that can obscure lesion severity when using traditional pressure-based indices such as fractional flow reserve (FFR). Computational fluid dynamics (CFD) can offer a detailed alternative haemodynamic assessment, but its prognostic value in non-haemodynamically significant tandem lesions remains unclear.</p><p><strong>Aims: </strong>We aimed to evaluate whether CFD-derived haemodynamic parameters could predict the 12-month progression of initially non-significant tandem lesions in the left anterior descending artery (LAD), defined by computed tomography (CT)-derived FFR (FFR-CT) >=0.80.</p><p><strong>Methods: </strong>In a retrospective cohort of 60 1:1 propensity score-matched patients with tandem LAD stenoses, baseline and 12-month follow-up coronary CT angiography were performed. FFR-CT was computed using patient-specific CFD simulations, where FFR was defined as the ratio of the mean distal to aortic pressure under simulated hyperaemic flow conditions. CFD simulations quantified the time-averaged wall shear stress (TAWSS), oscillatory shear index (OSI), and relative residence time (RRT). Lesion progression was defined as diameter stenosis >70% and/or FFR-CT <0.80 at follow-up.</p><p><strong>Results: </strong>Baseline CT-derived FFR did not differ significantly between groups. Patients with lesion progression (n=30) exhibited significantly lower baseline TAWSS (0.32±0.10 Pa vs 0.82±0.20 Pa; p<0.001), higher OSI (0.22±0.06 vs 0.05±0.03; p<0.001), and prolonged RRT (1.9±0.6 s vs 0.7±0.3 s; p<0.001) compared with those with stable lesions. Multivariate analysis confirmed TAWSS, OSI, RRT, age, and diabetes as independent predictors of progression.</p><p><strong>Conclusions: </strong>CFD-derived haemodynamic profiles strongly predict the 12-month progression of tandem LAD lesions despite a non-ischaemic baseline FFR-CT. The integration of CFD parameters with conventional physiology may improve the management of tandem coronary lesions beyond pressure-based indices alone.</p>","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"12 2","pages":"e115-e124"},"PeriodicalIF":0.0,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13397423/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148586177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AsiaInterventionPub Date : 2026-07-30eCollection Date: 2026-07-01DOI: 10.4244/AIJ-E-26-00001
Ehtisham Mahmud, Revathy Sampath-Kumar
{"title":"The robotic revolution in percutaneous coronary intervention: bridging the gap to clinical reality.","authors":"Ehtisham Mahmud, Revathy Sampath-Kumar","doi":"10.4244/AIJ-E-26-00001","DOIUrl":"10.4244/AIJ-E-26-00001","url":null,"abstract":"","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"12 2","pages":"e104-e106"},"PeriodicalIF":0.0,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13397421/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148586242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}