AsiaIntervention最新文献

{"title":"Double-kissing single-string culotte bifurcation stenting guided by optical coherence tomography.","authors":"Bernard Wong, Eugene Brian Wu","doi":"10.4244/AIJ-D-25-00038","DOIUrl":"10.4244/AIJ-D-25-00038","url":null,"abstract":"","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"12 1","pages":"60-61"},"PeriodicalIF":0.0,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12987388/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147470308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Flipping the focus - treating post-capillary pulmonary hypertension with pulmonary artery denervation.","authors":"Joseph P Hart, Mark G Davies","doi":"10.4244/AIJ-D-26-00006","DOIUrl":"10.4244/AIJ-D-26-00006","url":null,"abstract":"","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"12 1","pages":"14-16"},"PeriodicalIF":0.0,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12987389/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147470363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling the hidden: a surprising discovery in a patient with LAD in-stent restenosis.","authors":"Atul Kaushik, Avinash Mani, Vijay Kumar, Vishal Rastogi, Ashok Seth","doi":"10.4244/AIJ-D-25-00030","DOIUrl":"10.4244/AIJ-D-25-00030","url":null,"abstract":"","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"12 1","pages":"62-63"},"PeriodicalIF":0.0,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12987387/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147469939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Angiographic and functional assessment after paclitaxel or sirolimus drug-coated balloons for de novo coronary artery disease in small vessels: PICCOLETO VI study.","authors":"Simone Fezzi, Mauro Gitto, Aurora Trevisanello, Faisal Sharif, Gabriele Venturi, Jacek Bezubka, Sylwia Iwanczyk, Wojciech Wanha, Michał Hawranek, Maksymilian Mielczarek, Piotr Wańczura, Monica Verdoia, Pietro Pieri, Antonio Mugnolo, Bharat Khialani, Ilya Litovchik, Antoinette Monayer, Tuomas T Rissanen, Flavio Ribichini, Antonio Colombo, Bernardo Cortese","doi":"10.4244/AIJ-D-25-00057","DOIUrl":"10.4244/AIJ-D-25-00057","url":null,"abstract":"<p><strong>Background: </strong>Paclitaxel-coated balloons (PCB) have strong supporting evidence for use in small coronary vessels, while sirolimus-coated balloons (SCB) have shown variable angiographic results, raising questions about their overall effectiveness.</p><p><strong>Aims: </strong>The PICCOLETO VI study aimed to compare the angiographic and physiological outcomes of various PCB and SCB technologies in treating <i>de novo</i> coronary artery disease.</p><p><strong>Methods: </strong>This international, multicentre study included patients who underwent percutaneous coronary intervention and had elective angiographic follow-up 5-9 months later. Angiographic and physiological assessments were performed by a core laboratory, including Murray law-based quantitative flow ratio (μFR).</p><p><strong>Results: </strong>Based on a cohort of 293 patients, 227 lesions treated either with a PCB (n=148) or an SCB (n=79) were included. No differences in terms of baseline clinical or angiographic characteristics were reported between the two cohorts. PCB showed lower late lumen loss (-0.05±0.56 mm vs +0.10±0.59 mm; p=0.05) and a higher prevalence of late lumen enlargement (58.1% vs 40.5%; p=0.01). The primary endpoint of late functional loss was not statistically different, with a trend in favour of PCB (-0.01±0.15 vs +0.03±0.13; p=0.09). There was no difference in terms of target lesion failure, with a higher rate of ischaemia-inducing vessels at follow-up in the SCB group (14.9% vs 26.6%; p=0.03). A μFR <=0.86 following drug-coated balloon (DCB) treatment emerged as a reliable cutoff for predicting follow-up ischaemia, with an accuracy of 80%, whereas no significant interaction was observed for a post-DCB angiographic degree of stenosis >=30%.</p><p><strong>Conclusions: </strong>In this direct comparison between two classes of DCB, late functional loss was comparable between PCB and SCB, with PCB confirming superior angiographic performance.</p>","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"12 1","pages":"28-40"},"PeriodicalIF":0.0,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12987396/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147470305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Excimer laser coronary atherectomy-assisted percutaneous coronary intervention in complex coronary artery lesions: an early Indian experience.","authors":"Kirti Punamiya, A V Ganesh Kumar","doi":"10.4244/AIJ-D-25-00033","DOIUrl":"10.4244/AIJ-D-25-00033","url":null,"abstract":"<p><strong>Background: </strong>Excimer laser coronary atherectomy (ELCA) to modify or debulk atherosclerotic plaque during percutaneous coronary intervention (PCI) has been in clinical use for the past four decades. Primarily, ELCA was introduced to mitigate the challenges posed by routine PCI for complex lesions and in crossing resistant lesions.</p><p><strong>Aims: </strong>The aim of the present study was to evaluate the efficacy and safety of ELCA in complex coronary lesions.</p><p><strong>Methods: </strong>This study included 71 consecutive patients who underwent treatment with ELCA-assisted PCI for complex coronary lesions. The data were analysed for the incidence of procedural success and related complications with major adverse cardiovascular outcomes at baseline, post-procedure, 1-month and 6-month follow-up.</p><p><strong>Results: </strong>The study included 71 real-world patients with highly complex lesion subsets, comprising uncrossable chronic total occlusions (CTOs; 26 [33.77%]), moderately to heavily calcified lesions (33 [42.86%]), long diffused in-stent restenosis (ISR) lesions (30 [38.96%]), and ST-segment elevation myocardial infarction with a large thrombus burden (27 [35.06%]). The study population was predominantly male (87.32%), including 71 individuals with a mean age of 63.51±13.57 years. The mean left ventricular ejection fraction (LVEF) was 45.1±11.6%; however, 15 patients (21.13%) had an LVEF of <30%. A total of 31 (43.66%) patients had a SYNTAX score of >22. The direct use of maximum energy as a default setting was used in 52 patients (85.3%) and was not associated with any procedural or patient complications. No major adverse cardiac events (MACE) were reported during hospitalisation. The cumulative procedural success rate was 100%, and the device success rate was 96.10%. The 6-month incidence of MACE was significantly low at 2 (2.82%) and was attributed to target vessel revascularisations only.</p><p><strong>Conclusions: </strong>In this study, ELCA was observed to be an effective and safe device, making it a suitable alternative strategy for complex PCI in patients with difficult-to-cross lesions such as CTO, ISR, heavily thrombotic lesions, and calcified lesions. In difficult-to-cross lesions, even when the ELCA device failed to advance across, the delivered ELCA energy modified the lesion sufficiently to render it crossable. There were no safety concerns despite the direct use of maximum energy as a default strategy in this study population.</p>","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"12 1","pages":"50-57"},"PeriodicalIF":0.0,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12987393/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147470351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply: The AHEAD score in acute myocardial infarction: a call for more rigorous validation.","authors":"Mike Saji","doi":"10.4244/AIJ-D-25-00097","DOIUrl":"10.4244/AIJ-D-25-00097","url":null,"abstract":"","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"12 1","pages":"70-71"},"PeriodicalIF":0.0,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12987386/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147469945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Head-to-head comparison of limus- versus paclitaxel-coated balloons in the treatment of in-stent restenosis: a meta-analysis.","authors":"Marios Sagris, Stergios Soulaidopoulos, Nikolaos Ktenopoulos, Angelos Papanikolaou, Kyriakos Dimitriadis, Nikolaos Patsourakos, Dimitris Tousoulis, Bruno Scheller, Antonio Colombo, Konstantinos Tsioufis","doi":"10.4244/AIJ-D-25-00029","DOIUrl":"10.4244/AIJ-D-25-00029","url":null,"abstract":"<p><strong>Background: </strong>There is a lack of robust comparative data between limus drug-coated balloons (DCBs) versus paclitaxel-coated balloons (PCBs) on their efficacy and safety in treating in-stent restenosis (ISR).</p><p><strong>Aims: </strong>The objective of this systematic review and meta-analysis was to compare the efficacy and safety of limus DCBs versus PCBs in terms of clinical and angiographic outcomes during a 12-month follow-up.</p><p><strong>Methods: </strong>Following PRISMA guidelines, we systematically explored PubMed, Scopus, and Cochrane databases up to 20 February 2025 for studies comparing limus DCBs versus PCBs in terms of safety, efficacy, and angiographic outcomes in treating ISR. The primary outcomes were the incidence of clinically driven target lesion revascularisation (TLR) and failure (TLF). Secondary endpoints were major adverse cardiovascular events (MACE) and angiographic findings during follow-up.</p><p><strong>Results: </strong>Data from six randomised controlled trials (RCTs), including a total of 639 patients treated with limus DCBs and 569 with PCBs for ISR, were analysed with a mean follow-up of 12 months. In this analysis, all six RCTs reported on TLR (limus DCB 14% vs PCB 11.4%) and TLF (limus DCB 15% vs PCB 14%) incidence, showing no significant difference between the limus DCB and PCB groups. No significant differences were observed in MACE (16.4% vs 13.5%), all-cause mortality (1.8% vs 1.4%), cardiac death (1.4% vs 1.0%) or target vessel myocardial infarction (0.9% vs 1.0%), for limus DCBs versus PCBs, respectively. Angiographic outcomes showed no significant differences in post-intervention minimal lumen diameter (standardised mean difference [SMD] +0.06, 95% confidence interval [CI]: -0.07 to 0.18; I²=0%) or binary restenosis (limus DCB 19.5% vs PCB 12.9%) at follow-up between the groups. The risk of late lumen loss was also comparable between limus DCBs and PCBs for both in-segment (SMD +0.02, 95% CI: -0.18 to 0.23; I²=32%) and in-lesion (SMD -0.03, 95% CI: -0.31 to 0.24; I²=27%) analyses. Low heterogeneity was observed across the studies.</p><p><strong>Conclusions: </strong>Our findings suggest that limus DCBs are equally as effective and safe as PCBs for treating ISR, demonstrating non-inferiority in both clinical and angiographic outcomes at 12 months post-intervention.</p>","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"12 1","pages":"17-27"},"PeriodicalIF":0.0,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12987392/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147470348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Jailed drug-coated balloon technique: an enhanced provisional approach to complex, non-left main bifurcations.","authors":"Bharat Khialani, Eran Wen Jun Sim, George Touma, Tom Ford, Cuneyt Ada, Dharmaraj Karthikesan, Bernard Wong","doi":"10.4244/AIJ-D-25-00054","DOIUrl":"https://doi.org/10.4244/AIJ-D-25-00054","url":null,"abstract":"","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"12 1","pages":"58-59"},"PeriodicalIF":0.0,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12994463/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147488430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Many roads lead to Rome - the quest for optimal lesion preparation.","authors":"Bruno Scheller, Franz X Kleber","doi":"10.4244/AIJ-D-26-00005","DOIUrl":"10.4244/AIJ-D-26-00005","url":null,"abstract":"","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"12 1","pages":"11-13"},"PeriodicalIF":0.0,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12987385/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147470345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pulmonary artery denervation improves left ventricular diastolic function in patients with isolated post-capillary pulmonary hypertension secondary to heart failure with preserved ejection fraction: a safety and proof-of-principle cohort study.","authors":"Xiaomin Jiang, Hang Zhang, Juan Zhang, Yue Gu, Dujiang Xie, Zhimei Wang, Shao-Liang Chen","doi":"10.4244/AIJ-D-25-00061","DOIUrl":"10.4244/AIJ-D-25-00061","url":null,"abstract":"<p><strong>Background: </strong>The benefits of pulmonary artery denervation (PADN) for patients with isolated post-capillary pulmonary hypertension (IpcPH) secondary to left heart failure with preserved ejection fraction (HFpEF) remain unknown.</p><p><strong>Aims: </strong>This study aimed to evaluate the safety and feasibility of PADN in patients with HFpEF-induced IpcPH.</p><p><strong>Methods: </strong>This was a single-centre, proof-of-principle cohort study conducted in China. Patients with chronic HFpEF (>=6 months), receiving guideline-directed medical therapy for >=3 months, and meeting criteria for stage C heart failure and IpcPH were included. Eligible patients had New York Heart Association Class III or ambulatory Class IV symptoms and a plasma N-terminal prohormone B-type natriuretic peptide level >300 pg/mL. Right heart catheterisation was performed to assess haemodynamics, and the rate of change of left ventricular pressure (dP/dt) was monitored for 10 minutes following the PADN procedure.</p><p><strong>Results: </strong>At 10 minutes post-procedure, PADN resulted in a 16.9% reduction in mean pulmonary arterial pressure (PAP) and a 22.9% reduction in pulmonary artery wedge pressure (PAWP), with no significant changes in cardiac output, right atrial pressure, or pulmonary vascular resistance. Additionally, the minimum left ventricular dP/dt (dP/dtmin) significantly decreased from -1,698.9±322.9 mmHg/s at baseline to -2,048.0±442.3 mmHg/s (a 20.5% reduction; p=0.012), indicating improved left ventricular relaxation. However, the maximum dP/dt and left ventricular end-systolic pressure remained unchanged.</p><p><strong>Conclusions: </strong>PADN is associated with significant reductions in PAP and PAWP, likely driven by improved left ventricular relaxation, as reflected by dP/dtmin, in patients with HFpEF-induced IpcPH. ClinicalTrials.gov: NCT06323512.</p>","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"12 1","pages":"41-49"},"PeriodicalIF":0.0,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12987394/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147470384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}