AsiaInterventionPub Date : 2025-03-20eCollection Date: 2025-03-01DOI: 10.4244/AIJ-D-24-00029
Katie Wing Sum Fan, Ling Na Wong, Leo Kar Lok Lai, Simon Chi Ying Chow, Ka Lung Chui, Kevin Ka-Ho Kam, Randolph Hung Leung Wong, Alex Pui-Wai Lee, Kent Chak-Yu So
{"title":"Transcatheter tricuspid valve implantation with the Cardiovalve system.","authors":"Katie Wing Sum Fan, Ling Na Wong, Leo Kar Lok Lai, Simon Chi Ying Chow, Ka Lung Chui, Kevin Ka-Ho Kam, Randolph Hung Leung Wong, Alex Pui-Wai Lee, Kent Chak-Yu So","doi":"10.4244/AIJ-D-24-00029","DOIUrl":"10.4244/AIJ-D-24-00029","url":null,"abstract":"","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"11 1","pages":"62-63"},"PeriodicalIF":0.0,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11907267/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AsiaInterventionPub Date : 2025-03-20eCollection Date: 2025-03-01DOI: 10.4244/AIJ-E-25-00002
Ignacio J Amat-Santos, Akash Jain
{"title":"Gone long, not wrong: BioMime Morph and a tale of coronary ambition.","authors":"Ignacio J Amat-Santos, Akash Jain","doi":"10.4244/AIJ-E-25-00002","DOIUrl":"10.4244/AIJ-E-25-00002","url":null,"abstract":"","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"11 1","pages":"10-11"},"PeriodicalIF":0.0,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11905109/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Paclitaxel crystal visualisation by optical coherence tomography following drug-eluting balloon angioplasty of a late in-stent restenosis coronary lesion.","authors":"Rajesh Vijayvergiya, Satya S Mandava, Basant Kumar, Nikhil Sharma, Ankush Gupta","doi":"10.4244/AIJ-D-24-00049","DOIUrl":"https://doi.org/10.4244/AIJ-D-24-00049","url":null,"abstract":"","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"11 1","pages":"48-49"},"PeriodicalIF":0.0,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11905095/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AsiaInterventionPub Date : 2024-09-27eCollection Date: 2024-09-01DOI: 10.4244/AIJ-E-24-00006
Gian Paolo Ussia, Nino Cocco
{"title":"In-stent neoatherosclerosis: a new problem or an opportunity to rethink the treatment of coronary disease?","authors":"Gian Paolo Ussia, Nino Cocco","doi":"10.4244/AIJ-E-24-00006","DOIUrl":"https://doi.org/10.4244/AIJ-E-24-00006","url":null,"abstract":"","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"10 3","pages":"153-154"},"PeriodicalIF":0.0,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11413636/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142336712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AsiaInterventionPub Date : 2024-09-27eCollection Date: 2024-09-01DOI: 10.4244/AIJ-D-24-00013
M P Girish, Mohit D Gupta, Akiko Maehara, Mitsuaki Matsumura, Ankit Bansal, Shekhar Kunal, Vishal Batra, Arun Mohanty, Arman Qamar, Gary S Mintz, Ziad A Ali, Jamal Yusuf
{"title":"OCT-based comparative evaluation of culprit lesion morphology in very young versus older adult patients with STEMI.","authors":"M P Girish, Mohit D Gupta, Akiko Maehara, Mitsuaki Matsumura, Ankit Bansal, Shekhar Kunal, Vishal Batra, Arun Mohanty, Arman Qamar, Gary S Mintz, Ziad A Ali, Jamal Yusuf","doi":"10.4244/AIJ-D-24-00013","DOIUrl":"https://doi.org/10.4244/AIJ-D-24-00013","url":null,"abstract":"<p><strong>Background: </strong>The clinical and pathophysiological characteristics of coronary artery disease in very young adults are poorly described.</p><p><strong>Aims: </strong>Using optical coherence tomography (OCT), we compared culprit lesion morphology in very young adult patients (≤35 years) versus older adult patients (>60 years) with ST-segment elevation myocardial infarction (STEMI).</p><p><strong>Methods: </strong>Culprit lesion morphology was classified as plaque rupture, plaque erosion, or calcified nodule. Thrombus age was subclassified into acute (intraluminal thrombus with surface irregularity) or subacute (mostly mural thrombus with a smooth surface).</p><p><strong>Results: </strong>A total of 61 patients who underwent thrombolysis within 24 hours from symptom onset were included, with 38 (59.7%) subjects ≤35 years and 23 (40.3%) subjects >60 years of age. As an underlying mechanism of STEMI thrombosis, plaque erosion was more common in very young patients (52.6% vs 21.7%; p=0.02) while plaque rupture was more common in elderly patients (65.2% vs 36.8%; p=0.03). Acute or subacute thrombus was identified in 68.9% (42/61) of patients, with red thrombus being more frequent in very young patients. In the entire patient cohort, acute thrombus was more frequent in plaque rupture compared with plaque erosion (62.0% vs 28.0%; p=0.01), whereas subacute thrombus was more common in plaque erosion versus plaque rupture (52.0% vs 10.3%; p=0.0008).</p><p><strong>Conclusions: </strong>OCT showed that plaque erosion and plaque rupture were the most common underlying STEMI mechanisms in very young patients and older patients, respectively, and that subjects with plaque erosion had greater evidence of subacute thrombus.</p>","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"10 3","pages":"177-185"},"PeriodicalIF":0.0,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11413641/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142333630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of acute coronary syndrome on early in-stent neoatherosclerosis as shown by optical coherence tomography.","authors":"Kazuhiro Nakao, Takanori Yamazaki, Naoki Fujisawa, Yusuke Kure, Tomohiro Yamaguchi, Shunsuke Kagawa, Takenobu Shimada, Atsushi Shibata, Asahiro Ito, Kenichiro Otsuka, Yasuhiro Izumiya, Daiju Fukuda","doi":"10.4244/AIJ-D-24-00021","DOIUrl":"https://doi.org/10.4244/AIJ-D-24-00021","url":null,"abstract":"<p><strong>Background: </strong>Patients with acute coronary syndrome (ACS) have a higher risk of requiring target vessel revascularisation after percutaneous coronary intervention (PCI) than patients with stable angina. Neoatherosclerosis is a significant risk factor for very late stent thrombosis, and the presence of neoatherosclerosis is independently associated with major adverse cardiac events.</p><p><strong>Aims: </strong>In this study, we used optical coherence tomography (OCT) to investigate the impact of ACS on neoatherosclerosis within 1 year after PCI.</p><p><strong>Methods: </strong>We investigated 102 patients (122 lesions) who had undergone PCI using a second-generation drug-eluting stent (DES) from March 2017 to November 2020 and were followed up with OCT within 1 year. The patients were categorised into the ACS group or non-ACS group according to their clinical findings at the time of target lesion treatment. We used OCT to investigate the presence of neoatherosclerosis.</p><p><strong>Results: </strong>The ACS group comprised 23 (22.5%) patients. There were no differences in the patients' clinical characteristics between the groups. The total stent length tended to be shorter in the ACS group than in the non-ACS group (24 mm vs 32 mm, respectively; p=0.09), but this difference was not statistically significant. The median duration from PCI was 290 days. Neoatherosclerosis was more frequent in ACS lesions (39% vs 4%; p<0.01), and implantation of a DES in ACS lesions was an independent predictor of neoatherosclerosis occurrence (odds ratio 9.70; p<0.01).</p><p><strong>Conclusions: </strong>This observational study using OCT indicates that stenting for ACS lesions is associated with early in-stent neoatherosclerosis.</p>","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"10 3","pages":"203-211"},"PeriodicalIF":0.0,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11413567/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142333629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical safety and performance of the world's thinnest-strut Evermine50 everolimus-eluting stent: a 24-month follow-up of the Evermine 50 EES - 1 study.","authors":"Sivaprasad Kunjukrishnapilla, Jaspal Arneja, Dilip Kumar, Parneesh Arora, Raghu R Thagachagere, Manohar Ganesan, Deepak Davidson, Sanjeeb Roy, Subhash Chandra, Ashokkumar Thakkar","doi":"10.4244/AIJ-D-24-00009","DOIUrl":"https://doi.org/10.4244/AIJ-D-24-00009","url":null,"abstract":"<p><strong>Background: </strong>Ultrathin-strut stents are considered the future of percutaneous coronary intervention for treating coronary artery disease (CAD). These drug-eluting stents with biodegradable-polymer technology have the potential to improve clinical outcomes in CAD patients.</p><p><strong>Aims: </strong>This study aimed to evaluate the safety and performance of newer-generation ultrathin-strut (50 µm) Evermine50 everolimus-eluting stents (EES) in patients with single or multiple long lesions.</p><p><strong>Methods: </strong>This is a prospective, single-arm, multicentre study conducted in India that enrolled 118 patients with <i>de novo</i> coronary lesions. The endpoints were defined based on the major adverse cardiac events (MACE; composite of cardiac death, myocardial infarction [MI] and clinically driven target lesion revascularisation) up to 24-month follow-up. A subset of patients (n=21) underwent angiographic follow-up for a mean follow-up period of 12 mon.</p><p><strong>Results: </strong>A total of 138 lesions were successfully treated in 118 patients, the majority of whom were males (80.51%). The average stent length and diameter deployed were 26.02±9.24 mm and 2.97±0.36 mm, respectively. The results exhibited low MACE at 24-month follow-up (0.87%) with no stent thrombosis and 1 death (0.87%, which was cardiac). The core lab angiographic assessment showed in-segment and in-device late lumen loss of 0.12±0.31 mm and 0.17±0.31 mm, respectively, at a mean follow-up of 12 months, with clinically acceptable outcomes.</p><p><strong>Conclusions: </strong>The Evermine50 EES showed satisfactory primary clinical as well as angiographic outcomes, reaffirming the safety and performance of the world's thinnest-strut stent by exhibiting low rates of MACE at 24-month follow-up with an absence of any stent thrombosis and MI. Clinical Trials Registry-India (CTRI) number: CTRI/2017/02/007781.</p>","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"10 3","pages":"195-202"},"PeriodicalIF":0.0,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11413568/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142333626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AsiaInterventionPub Date : 2024-09-27eCollection Date: 2024-09-01DOI: 10.4244/AIJ-E-24-00004
Simon Eccleshall, Bruno Scheller
{"title":"Less metal - the latest evolution in PCI.","authors":"Simon Eccleshall, Bruno Scheller","doi":"10.4244/AIJ-E-24-00004","DOIUrl":"https://doi.org/10.4244/AIJ-E-24-00004","url":null,"abstract":"","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"10 3","pages":"155-156"},"PeriodicalIF":0.0,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11413634/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142336714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AsiaInterventionPub Date : 2024-09-27eCollection Date: 2024-09-01DOI: 10.4244/AIJ-D-23-00023
Caitlin Fern Wee, Claire Jing-Wen Tan, Chun En Yau, Yao Hao Teo, Rachel Go, Yao Neng Teo, Benjamin Kye Jyn, Nicholas L Syn, Hui-Wen Sim, Jason Z Chen, Raymond C C Wong, James W Yip, Huay-Cheem Tan, Tiong-Cheng Yeo, Ping Chai, Tony Y W Li, Wesley L Yeung, Andie H Djohan, Ching-Hui Sia
{"title":"Accuracy of machine learning in predicting outcomes post-percutaneous coronary intervention: a systematic review.","authors":"Caitlin Fern Wee, Claire Jing-Wen Tan, Chun En Yau, Yao Hao Teo, Rachel Go, Yao Neng Teo, Benjamin Kye Jyn, Nicholas L Syn, Hui-Wen Sim, Jason Z Chen, Raymond C C Wong, James W Yip, Huay-Cheem Tan, Tiong-Cheng Yeo, Ping Chai, Tony Y W Li, Wesley L Yeung, Andie H Djohan, Ching-Hui Sia","doi":"10.4244/AIJ-D-23-00023","DOIUrl":"https://doi.org/10.4244/AIJ-D-23-00023","url":null,"abstract":"<p><strong>Background: </strong>Recent studies have shown potential in introducing machine learning (ML) algorithms to predict outcomes post-percutaneous coronary intervention (PCI).</p><p><strong>Aims: </strong>We aimed to critically appraise current ML models' effectiveness as clinical tools to predict outcomes post-PCI.</p><p><strong>Methods: </strong>Searches of four databases were conducted for articles published from the database inception date to 29 May 2021. Studies using ML to predict outcomes post-PCI were included. For individual post-PCI outcomes, measures of diagnostic accuracy were extracted. An adapted checklist comprising existing frameworks for new risk markers, diagnostic accuracy, prognostic tools and ML was used to critically appraise the included studies along the stages of the translational pathway: development, validation, and impact. Quality of training data and methods of dealing with missing data were evaluated.</p><p><strong>Results: </strong>Twelve cohorts from 11 studies were included with a total of 4,943,425 patients. ML models performed with high diagnostic accuracy. However, there are concerns over the development of the ML models. Methods of dealing with missing data were problematic. Four studies did not discuss how missing data were handled. One study removed patients if any of the predictor variable data points were missing. Moreover, at the validation stage, only three studies externally validated the models presented. There could be concerns over the applicability of these models. None of the studies discussed the cost-effectiveness of implementing the models.</p><p><strong>Conclusions: </strong>ML models show promise as a useful clinical adjunct to traditional risk stratification scores in predicting outcomes post-PCI. However, significant challenges need to be addressed before ML can be integrated into clinical practice.</p>","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"10 3","pages":"219-232"},"PeriodicalIF":0.0,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11413637/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142333625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AsiaInterventionPub Date : 2024-09-27eCollection Date: 2024-09-01DOI: 10.4244/AIJ-E-24-00005
Azfar G Zaman, Abhishek Kumar
{"title":"Less is more: a new \"thin-king\" for DES?","authors":"Azfar G Zaman, Abhishek Kumar","doi":"10.4244/AIJ-E-24-00005","DOIUrl":"https://doi.org/10.4244/AIJ-E-24-00005","url":null,"abstract":"","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"10 3","pages":"151-152"},"PeriodicalIF":0.0,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11413633/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142336713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}