AsiaInterventionPub Date : 2024-02-29eCollection Date: 2024-02-01DOI: 10.4244/AIJ-D-23-00005
Manish Narang, Aseem Saxena, Ramneek Kaur, Hanumanthu Reddy Gopa, Nick E J West
{"title":"Variability in research culture across busy catheterisation labs in the Asia-Pacific region.","authors":"Manish Narang, Aseem Saxena, Ramneek Kaur, Hanumanthu Reddy Gopa, Nick E J West","doi":"10.4244/AIJ-D-23-00005","DOIUrl":"10.4244/AIJ-D-23-00005","url":null,"abstract":"<p><strong>Background: </strong>Information related to research culture in the busy catheterisation (cath) labs across the Asia-Pacific (APAC) region is sparse.</p><p><strong>Aims: </strong>The aims of this study were to examine the variability in research culture in busy cath labs in the APAC region and to propose a roadmap for hospitals to develop in-house research capabilities in conjunction with industry and academia.</p><p><strong>Methods: </strong>Data related to research practices in the APAC region were collected from busy cath labs (at least 250 angioplasty/year) and analysed. Results were shared with research experts to understand the challenges in institutional research and create a roadmap for hospitals to develop research capabilities.</p><p><strong>Results: </strong>A total of 220 respondents from 62 cath labs (88.6%) across 13 APAC countries participated in the survey. A wide variation was noted in research culture across APAC countries. Well-established infrastructure was reported in Australia, New Zealand, South Korea, Singapore, and Japan. Large multicentre trials were common in South Korea, while routine follow-ups were common in Japan. Linking medical records across hospitals/states was considered challenging. Research exposure and training were limited in the APAC region. The experts suggested a roadmap, including creating a conducive regulatory environment, forming synergistic goals, training programs for the professionals involved in research, and leveraging best practices, for improving the research culture in APAC.</p><p><strong>Conclusions: </strong>Clinical research in cardiology has grown significantly in the APAC region, with a huge research potential in China and India. Implementing measures to improve research training and involvement of the industry will boost the research culture in the APAC region.</p>","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"10 1","pages":"26-33"},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10900241/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139998453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AsiaInterventionPub Date : 2024-02-29eCollection Date: 2024-02-01DOI: 10.4244/AIJ-D-23-00022
Nicholas Tan, Gao Fei, Mohammed Rizwan Amanullah, Soo Teik Lim, Zameer Abdul Aziz, Sivaraj Govindasamy, Victor Tar Toong Chao, See Hooi Ewe, Kay Woon Ho, Jonathan Yap
{"title":"Safety and efficacy of cerebral embolic protection in transcatheter aortic valve implantation: an updated meta-analysis.","authors":"Nicholas Tan, Gao Fei, Mohammed Rizwan Amanullah, Soo Teik Lim, Zameer Abdul Aziz, Sivaraj Govindasamy, Victor Tar Toong Chao, See Hooi Ewe, Kay Woon Ho, Jonathan Yap","doi":"10.4244/AIJ-D-23-00022","DOIUrl":"10.4244/AIJ-D-23-00022","url":null,"abstract":"<p><strong>Background: </strong>The use of cerebral embolic protection devices during transcatheter aortic valve implantation (TAVI) reveals conflicting data.</p><p><strong>Aims: </strong>This updated meta-analysis aims to evaluate the efficacy and safety of the SENTINEL Cerebral Protection System.</p><p><strong>Methods: </strong>A literature search for relevant studies up to September 2022 was performed. Study outcomes were divided based on time period - overall (up to 30 days) and short (≤7 days). The outcomes studied include stroke (disabling, non-disabling), mortality, neuroimaging findings, transient ischaemic attack, acute kidney injury and major vascular and bleeding complications.</p><p><strong>Results: </strong>A total of 15 studies involving 294,134 patients were included. Regarding overall outcomes, significant reductions were noted for mortality (odds ratio [OR] 0.60, 95% confidence interval [CI]: 0.41-0.88; p=0.008), all stroke (OR 0.64, 95% CI: 0.46-0.88; p=0.006) and disabling stroke (OR 0.42, 95% CI: 0.23-0.74; p=0.003) using the SENTINEL device. No significant differences were noted for other outcomes. There was significant heterogeneity across the studies for mortality (p=0.013) and all stroke (p=0.003). Including only randomised data (n=4), there was only significant reduction in the incidence of disabling stroke (OR 0.39, 95% CI: 0.17-0.89; p=0.026) in the SENTINEL group. In studies reporting ≤7-day outcomes (n=8), use of the SENTINEL device demonstrated significantly lower rates of all stroke (p<0.001), disabling stroke (p<0.001) and major bleeding complications (p=0.02). No differences in neuroimaging outcomes were noted.</p><p><strong>Conclusions: </strong>In this updated meta-analysis, use of the SENTINEL Cerebral Protection System was associated with lower rates of mortality, all stroke and disabling stroke, although significant heterogeneity was noted for mortality and all stroke. Including exclusively randomised data, there was only significant reduction in the incidence of disabling stroke. No significant adverse outcomes with device use were noted.</p>","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"10 1","pages":"51-59"},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10900717/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139998451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AsiaInterventionPub Date : 2024-02-29eCollection Date: 2024-02-01DOI: 10.4244/AIJ-D-23-00041
Matteo Bruno, Gianmarco Iannopollo, Laura Sofia Cardelli, Alessandro Capecchi, Valerio Lanzilotti, Roberto Verardi, Chiara Pedone, Giampiero Nobile, Gianni Casella
{"title":"Efficacy and safety of a minimalistic balloon aortic valvuloplasty strategy in a centre without heart surgery.","authors":"Matteo Bruno, Gianmarco Iannopollo, Laura Sofia Cardelli, Alessandro Capecchi, Valerio Lanzilotti, Roberto Verardi, Chiara Pedone, Giampiero Nobile, Gianni Casella","doi":"10.4244/AIJ-D-23-00041","DOIUrl":"10.4244/AIJ-D-23-00041","url":null,"abstract":"<p><strong>Background: </strong>Balloon aortic valvuloplasty (BAV) is a palliative tool for patients with symptomatic severe aortic stenosis (AS) at prohibitive risk for surgery or as a bridge to surgical aortic valve replacement (SAVR) or transcatheter aortic valve replacement (TAVR). BAV is traditionally performed in hospitals with onsite cardiac surgery due to its potential complications.</p><p><strong>Aims: </strong>The aim of this study was to evaluate the safety of BAV procedures performed by trained high-volume operators in a centre without onsite surgery and to assess the effect of a minimalistic approach to reduce periprocedural complications.</p><p><strong>Methods: </strong>From 2016 to 2021, 187 BAV procedures were performed in 174 patients. Patients were elderly (mean age: 85.0±5.4 years) and had high-risk (mean European System for Cardiac Operative Risk Evaluation score [EuroSCORE] II: 10.1±9.9) features. According to the indications, 4 cohorts were identified: 1) bridge to TAVR (n=98; 56%); 2) bridge to SAVR (n=8; 5%); 3) cardiogenic shock (n=11; 6%); and 4) palliation (n=57; 33%). BAV procedures were performed using the standard retrograde technique via femoral access in 165 patients (95%), although radial access was used in 9 patients (5%). Ultrasound-guided vascular puncture was performed in 118 patients (72%) and left ventricular pacing was administered through a stiff guidewire in 105 cases (60%).</p><p><strong>Results: </strong>BAV safety was confirmed by 1 periprocedural death (0.6%), 1 intraprocedural stroke (0.6%), 2 major vascular complications (1%) and 9 minor vascular complications (5%). Nine cases of in-hospital mortality occurred (5%), predominantly in patients with cardiogenic shock.</p><p><strong>Conclusions: </strong>BAV is a safe procedure that can be performed in centres without onsite cardiac surgery using a minimalistic approach that can reduce periprocedural complications.</p>","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"10 1","pages":"40-50"},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10900243/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139998816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AsiaInterventionPub Date : 2024-02-29eCollection Date: 2024-02-01DOI: 10.4244/AIJ-E-23-00006
Mirvat Alasnag, Mognee Alameer
{"title":"Interventional cardiology: a 2023 recap and what to expect in 2024.","authors":"Mirvat Alasnag, Mognee Alameer","doi":"10.4244/AIJ-E-23-00006","DOIUrl":"10.4244/AIJ-E-23-00006","url":null,"abstract":"","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"10 1","pages":"10-11"},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10900238/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139998448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AsiaInterventionPub Date : 2024-02-29eCollection Date: 2024-02-01DOI: 10.4244/AIJ-D-23-00026
Michael Chiang, Ivan Wong, Shing Fung Chui, Chi Yuen Eric Wong, Pedro A Villablanca, Michael Kang-Yin Lee
{"title":"First-in-Asia native valve modified-BASILICA TAVR with CT fusion, complicated by annular rupture rescued with coil embolisation.","authors":"Michael Chiang, Ivan Wong, Shing Fung Chui, Chi Yuen Eric Wong, Pedro A Villablanca, Michael Kang-Yin Lee","doi":"10.4244/AIJ-D-23-00026","DOIUrl":"10.4244/AIJ-D-23-00026","url":null,"abstract":"","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"10 1","pages":"60-61"},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10900240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139998447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A 2024 scientific update on the clinical performance of drug-coated balloons.","authors":"Florin-Leontin Lazar, Horea-Laurentiu Onea, Dan-Mircea Olinic, Bernardo Cortese","doi":"10.4244/AIJ-D-23-00010","DOIUrl":"10.4244/AIJ-D-23-00010","url":null,"abstract":"<p><p>Continuous advances in the field of interventional cardiology have led to the development of drug-coated balloons (DCB). These represent a promising device for overcoming the well-known limitations of traditional metallic stents, which are associated with a persistent yearly increased risk of adverse events. This technology has the ability to homogeneously transfer the drug into the vessel wall in the absence of a permanent prosthesis implanted in the coronary vessel. Robust data support the use of DCB for the treatment of in-stent restenosis, but there is also currently growing evidence from long-term follow-up of large randomised clinical trials regarding the use of these devices in other scenarios, such as de novo small and large vessel disease, complex bifurcations, and diffuse coronary disease. Other critical clinical settings such as diabetes mellitus, high bleeding risk patients and acute coronary syndromes could be approached in the upcoming future by using DCB, alone or as part of a blended strategy in combination with drug-eluting stents. There have been important scientific and technical advances in the DCB field in recent years. The purpose of this paper is to review the most current data regarding the use of DCB, including the mid- and long-term follow-up reports on the safety and efficacy of this novel strategy in different clinical and angiographic scenarios.</p>","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"10 1","pages":"15-25"},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10900242/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139998392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AsiaInterventionPub Date : 2024-02-29eCollection Date: 2024-02-01DOI: 10.4244/AIJ-D-23-00034
Himanshu Gupta, Navjyot Kaur, Pruthvi C Revaiah
{"title":"Modified proximal optimisation technique for long left main interventions to prevent stent elongation.","authors":"Himanshu Gupta, Navjyot Kaur, Pruthvi C Revaiah","doi":"10.4244/AIJ-D-23-00034","DOIUrl":"10.4244/AIJ-D-23-00034","url":null,"abstract":"","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"10 1","pages":"38-39"},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10902656/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139998449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AsiaInterventionPub Date : 2023-09-21eCollection Date: 2023-09-01DOI: 10.4244/AIJ-D-22-00079
Hirofumi Hioki, Yusuke Watanabe, Akihisa Kataoka, Hideyuki Kawashima, Ken Kozuma
{"title":"Attention when performing transcatheter valve-in-valve procedures in degenerative INSPIRIS RESILIA valves: a case of malfunction in the expansion zone.","authors":"Hirofumi Hioki, Yusuke Watanabe, Akihisa Kataoka, Hideyuki Kawashima, Ken Kozuma","doi":"10.4244/AIJ-D-22-00079","DOIUrl":"https://doi.org/10.4244/AIJ-D-22-00079","url":null,"abstract":"","PeriodicalId":72310,"journal":{"name":"AsiaIntervention","volume":"9 2","pages":"168-169"},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507603/pdf/AIJ-D-22-00079_Hioki.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41162820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}