Archive of clinical cases最新文献_第9页

New onset severe ulcerative colitis following Ixekizumab therapy. 伊谢珠单抗治疗后新发严重溃疡性结肠炎。

Archive of clinical cases Pub Date : 2022-01-01 DOI: 10.22551/2022.37.0904.10227

Alina Mihaela Morosanu, Ioana Ruxandra Mihai, Ioana Irina Rezus, Otilia Gavrilescu, Mihaela Dranga, Cristina Cijevschi Prelipcean, Catalina Mihai

引用次数: 4

Lower limb arterial thrombosis followed by sub-massive pulmonary thromboembolism after Sinopharm BBIBP-CorV COVID-19 vaccination. 国药BBIBP-CorV - COVID-19疫苗接种后下肢动脉血栓形成继发亚块状肺血栓栓塞。

Archive of clinical cases Pub Date : 2022-01-01 DOI: 10.22551/2022.37.0904.10222

Hamidreza Zaheri, Arda Kiani, Siamak Afaghi, Fatemehsadat Rahimi, Mohammadhossein Banitorfi, Amirmohammad Kazemzadeh Norozi, Samaneh Hashemi, Atefeh Abedini

{"title":"Lower limb arterial thrombosis followed by sub-massive pulmonary thromboembolism after Sinopharm BBIBP-CorV COVID-19 vaccination.","authors":"Hamidreza Zaheri, Arda Kiani, Siamak Afaghi, Fatemehsadat Rahimi, Mohammadhossein Banitorfi, Amirmohammad Kazemzadeh Norozi, Samaneh Hashemi, Atefeh Abedini","doi":"10.22551/2022.37.0904.10222","DOIUrl":"https://doi.org/10.22551/2022.37.0904.10222","url":null,"abstract":"The global COVID-19 vaccination had an undeniable influence on the pandemic management, despite of having reported rare but life-threatening side-effects of vaccines. Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare autoimmune complication determined by thrombocytopenia and thrombosis propensity in the circulatory system. The activation of antibodies against platelet factor-4 (PF-4) which mimics the heparin-induced thrombocytopenia (HIT) characteristic is the main known pathogenicity of the disease. Herein, we reported a case of VITT in a middle-aged woman with no previous history of thrombophilia or other medical conditions who presented with thrombosis of the left superficial femoral artery 3-days after receiving the second dose of inactivated BBIBP-CorV (Sinopharm) vaccine. The patient underwent bypass vascular surgery and received none-heparin anticoagulation consistent with high-dose intravenous immunoglobin. Eight days after the discharge, she was subsequently referred to our center with the presentation of sub-massive pulmonary thromboembolism in spite of receiving the prophylactic anticoagulants during follow-up period. Details on side-effects of COVID-19 vaccines, specifically the inactivated ones are yet to be fully ascertained. Clinicians should consider the history of COVID-19 vaccines in thromboembolism patients who do not have well-acknowledged risk factors. Further studies about the necessity of prophylactic anticoagulants and clinical judgment for receiving other vaccines in such patients are required.","PeriodicalId":72274,"journal":{"name":"Archive of clinical cases","volume":"9 4","pages":"150-153"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c8/f4/acc-09-04-150.PMC9769072.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10511193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Hypoxic ischemic brain injury with status myoclonus in a case with post-operative massive pulmonary thromboembolism: A diagnostic and therapeutic challenge. 缺氧缺血性脑损伤伴肌阵挛1例术后大块肺血栓栓塞:诊断和治疗的挑战。

Archive of clinical cases Pub Date : 2022-01-01 DOI: 10.22551/2022.37.0904.10225

Ritwick Mondal, Somesh Saha, Shramana Deb, Rahul Jain, Arindam Maitra, Manoj Mahata

{"title":"Hypoxic ischemic brain injury with status myoclonus in a case with post-operative massive pulmonary thromboembolism: A diagnostic and therapeutic challenge.","authors":"Ritwick Mondal, Somesh Saha, Shramana Deb, Rahul Jain, Arindam Maitra, Manoj Mahata","doi":"10.22551/2022.37.0904.10225","DOIUrl":"https://doi.org/10.22551/2022.37.0904.10225","url":null,"abstract":"Thromboembolic event is an important and widely regarded risk factor, influencing the outcome and overall survival in post-operative cases with second highest association with gynaecological surgeries. Here we report a 52 years old female who underwent total laparoscopic hysterectomy with bilateral salpingo-oophorectomy (TLH+BSO) presented to our emergency in unconscious and intubated state on her post-operative day-1 with cardiorespiratory failure. Based on the immediate investigations after successful resuscitation, an initial diagnosis of massive pulmonary thromboembolism was made following supportive and conservative management. Interestingly on subsequent days she started to display episodic non-rhythmic symmetric myoclonic jerks persisting for seconds to minutes; resembling 'post-hypoxic' or 'post-anoxic' status myoclonus due to hypoxic ischemic brain injury. Further neuro-electrophysiological examination revealed rhythmic well-formed delta activity on both sides symmetrically with a transformation into theta activity with forward displacement on subsequent days, bilaterally over the same areas. Later on, magnetic resonance imaging with magnetic resonance-spectroscopic findings also corroborated to hypoxic ischemic brain injury related changes over bilateral basal ganglia mostly in caudate nucleus. Post operative venous thromboembolism is a major clinical challenge and a subject of constant intensive care yet the neurological sequalae of such event is given less priority despite of its major contribution on overall prognostic and survival index.","PeriodicalId":72274,"journal":{"name":"Archive of clinical cases","volume":"9 4","pages":"161-169"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3d/22/acc-09-04-161.PMC9769078.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10870320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Post-polypectomy coagulation syndrome: a tricky to diagnose hot snare problem that can be eliminated thanks to cold snare revolution. 息肉切除术后凝血综合征:一个棘手的诊断热陷阱问题，可以消除由于冷陷阱革命。

Archive of clinical cases Pub Date : 2022-01-01 DOI: 10.22551/2022.37.0904.10226

Maria Zachou, Konstantinos Pikramenos, Georgios Mpetsios, Efthimia Lalla, Maria Panoutsakou, Konstantinos Varytimiadis, Panayiotis Karantanos

引用次数: 0

Accordion sign in COVID 19 related acute myocarditis, an old sign for a novel context? A cardiac magnetic resonance case series report study. COVID - 19相关急性心肌炎的手风琴征:新情况下的旧标志?心脏磁共振病例系列报告研究。

Archive of clinical cases Pub Date : 2022-01-01 DOI: 10.22551/2022.36.0903.10214

Francesco Mangini, Elvira Bruno, Robert W W Biederman, Roberto Del Villano, Roberto Rosato, Eluisa Muscogiuri

{"title":"Accordion sign in COVID 19 related acute myocarditis, an old sign for a novel context? A cardiac magnetic resonance case series report study.","authors":"Francesco Mangini, Elvira Bruno, Robert W W Biederman, Roberto Del Villano, Roberto Rosato, Eluisa Muscogiuri","doi":"10.22551/2022.36.0903.10214","DOIUrl":"https://doi.org/10.22551/2022.36.0903.10214","url":null,"abstract":"Introduction: The COVID-19 pandemic is related to a higher incidence of myocarditis; we present a case series of seven patients, admitted with COVID-19 related acute myocarditis, evaluated with cardiac magnetic resonance imaging, showing an altered profile of the free wall of the right ventricle, no longer present after six months follow-up.Materials and methods: Seven patients have been evaluated for COVID-19 related acute myocarditis, all patients have been evaluated with cardiac magnetic resonance imaging both in the acute setting and after six months follow-up.Results: In the acute phase, myocarditis was confirmed in keeping with the current diagnostic criteria. In five out of seven cases, the presence of a crinkling profile of the free wall of the right ventricle was observed; at six months follow up, remission in four out of the five cases and a significant reduction in the remaining case, of the previously described findings, was observed.Conclusions: Crinkling appearance in the profile of the free wall of the right ventricle, detectable with cardiac magnetic resonance imaging, might represent a morphological feature present in the acute setting of COVID-19 related myocarditis; several underlying physiopathological mechanisms are conceivable. Further studies are needed to confirm this correlation, define the underlying mechanisms and the prognostic implication related to it. This is the first report in the literature that has considered such findings to the best of our knowledge.","PeriodicalId":72274,"journal":{"name":"Archive of clinical cases","volume":"9 3","pages":"112-116"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/49/b1/acc-09-03-112.PMC9512132.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9286743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Drug induced erythema multiforme of the oral cavity. 药物性口腔多形性红斑。

Archive of clinical cases Pub Date : 2022-01-01 DOI: 10.22551/2022.37.0904.10224

Nalini Aswath, Rajalakshmi Rakshana

{"title":"Drug induced erythema multiforme of the oral cavity.","authors":"Nalini Aswath, Rajalakshmi Rakshana","doi":"10.22551/2022.37.0904.10224","DOIUrl":"https://doi.org/10.22551/2022.37.0904.10224","url":null,"abstract":"Drug induced erythema multiforme (EM) is a rare clinical entity which majorly involves the oral cavity. It commonly occurs due to intake of drugs such as NSAID'S, certain antibiotics, and anticonvulsants. It is characterized by rapidly rupturing vesicles leading to ill-defined erosions in the oral cavity and encrusted lip lesions. These lesions are usually difficult to differentiate from other vesiculo bullous and ulcerative lesions which would have a similar presentation and the absence of skin lesions can sometimes lead to misdiagnosis. Drug induced EM has an acute onset and is a self-limiting inflammatory hypersensitivity reaction that causes blistering and ulcerations of the skin and mucous membrane. The lesions heal following the discontinuation of the causative medications. This case report describes a case of drug induced erythema multiforme of the oral cavity that occurred consequent to the intake of Tab.Diclofenac Sodium and Tab.Cephelexin. The patient developed painful, bleeding, burning ulcerations with severe crustations on the upper, and lower lip, lateral and ventral surface of tongue, hard palate and retro molar regions. The case was managed with corticosteroids.","PeriodicalId":72274,"journal":{"name":"Archive of clinical cases","volume":"9 4","pages":"157-160"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9d/83/acc-09-04-157.PMC9769071.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10574061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Adult onset Xanthogranuloma presenting as a solitary laryngeal localization: case report and review of literature. 成人发性黄色肉芽肿表现为喉部单发定位:病例报告及文献回顾。

Archive of clinical cases Pub Date : 2022-01-01 DOI: 10.22551/2022.37.0904.10221

Gianluca Velletrani, Beatrice Francavilla, Valentina Rosati, Belen Padial, Lucia Anemona, Stefano Di Girolamo

{"title":"Adult onset Xanthogranuloma presenting as a solitary laryngeal localization: case report and review of literature.","authors":"Gianluca Velletrani, Beatrice Francavilla, Valentina Rosati, Belen Padial, Lucia Anemona, Stefano Di Girolamo","doi":"10.22551/2022.37.0904.10221","DOIUrl":"https://doi.org/10.22551/2022.37.0904.10221","url":null,"abstract":"Juvenile Xanthogranuloma (XG) is a rare disorder that belongs to the heterogeneous group of histiocytic neoplasms, characterized by a clonal expansion of non-Langerhans cell histiocytes that share a dermal macrophage phenotype. Although the head and neck region is the most common reported site of involvement by the Juvenile Xanthogranuloma family, laryngeal localization is extremely rare. We report a unique case of Adult Onset Xanthogranuloma with subglottic localization, presenting as a solitary laryngeal mass without other systemic or cutaneous lesions. A review of the previously described cases of laryngeal Xanthogranuloma has been performed, highlighting 7 cases of Juvenile Xanthogranuloma and only 3 cases of Adult Onset Xanthogranuloma. Despite the extreme rarity of laryngeal localization of XG, this histiocytic neoplasm should be considered as a differential diagnosis for laryngeal masses causing airway obstruction, even in the absence of other concomitant manifestations.","PeriodicalId":72274,"journal":{"name":"Archive of clinical cases","volume":"9 4","pages":"145-149"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/de/b7/acc-09-04-145.PMC9769079.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10511187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gut-brain axis: Review on the association between Parkinson's disease and plant lectins. 肠脑轴:帕金森病与植物凝集素关系的研究进展。

Archive of clinical cases Pub Date : 2022-01-01 DOI: 10.22551/2022.37.0904.10228

Kayvon Moin, Carly Funk, Meagan Josephs, Kyle Coombes, Madeleine Yeakle, Dhir Gala, Mohammad Ahmed-Khan

{"title":"Gut-brain axis: Review on the association between Parkinson's disease and plant lectins.","authors":"Kayvon Moin, Carly Funk, Meagan Josephs, Kyle Coombes, Madeleine Yeakle, Dhir Gala, Mohammad Ahmed-Khan","doi":"10.22551/2022.37.0904.10228","DOIUrl":"https://doi.org/10.22551/2022.37.0904.10228","url":null,"abstract":"Gastrointestinal (GI) involvement in the pathogenesis of Parkinson's Disease (PD) has been widely recognized and supported in recent literature. Prospective and retrospective studies found non-motor symptoms within the GI, specifically constipation, precede cardinal signs and cognitive decline by almost 20 years. In 2002, Braak et al. were the first to propose that PD is a six-stage propagating neuropathological process originating from the GI tract (GIT). Aggregated α-synuclein (α-syn) protein from the GIT is pathognomonic for the development of PD. This article reviews the current literature from the past 10 years as well as original research found in PubMed on the combined effects of enteric glial cells and lectins on the development of Parkinson's Disease. Studies have found that these aggregated and phosphorylated proteins gain access to the brain via retrograde transport through fast and slow fibers of intestinal neurons. Plant lectins, commonly found within plant-based diets, have been found to induce Leaky Gut Syndrome and can activate enteric glial cells, causing the release of pro-inflammatory cytokines. Oxidative stress on the enteric neurons, caused by a chronic neuro-inflammatory state, can cause a-syn aggregation and lead to Lewy Body formation, a hallmark finding in PD. Although the current literature provides a connection between the consumption of plant lectins and the pathophysiology of PD, further research is required to evaluate confounding variables such as food antigen mimicry and other harmful substances found in our diets.","PeriodicalId":72274,"journal":{"name":"Archive of clinical cases","volume":"9 4","pages":"177-183"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cc/90/acc-09-04-177.PMC9769076.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10511189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Peripheral T-Cell Lymphoma, Not Otherwise Specified - a case report and short literature review. 外周t细胞淋巴瘤，无其他特异性- 1例报告和简短的文献回顾。

Archive of clinical cases Pub Date : 2022-01-01 DOI: 10.22551/2022.37.0904.10220

Rafael Henriques de Figueiredo, Beatriz Simão Parreira, Pedro Amoroso Canão, Leila Cardoso, Elsa Fonseca, Jorge Almeida

{"title":"Peripheral T-Cell Lymphoma, Not Otherwise Specified - a case report and short literature review.","authors":"Rafael Henriques de Figueiredo, Beatriz Simão Parreira, Pedro Amoroso Canão, Leila Cardoso, Elsa Fonseca, Jorge Almeida","doi":"10.22551/2022.37.0904.10220","DOIUrl":"https://doi.org/10.22551/2022.37.0904.10220","url":null,"abstract":"Peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS) is the most common subgroup of peripheral T-cell lymphomas (PTCL), and constitutes a diagnosis of exclusion. At presentation, most patients exhibit B symptoms and generalized lymphadenopathy, with or without concomitant extra-nodal involvement. We present a case of a man admitted to the hospital with B symptoms, generalized lymphadenopathy and a pruritic exanthema. Laboratory workup reveled persistent eosinophilia and malignant hypercalcemia. The excisional lymph node biopsy diagnosed PTCL-NOS, and the skin biopsy demonstrated a lichenoid dermatitis, compatible with the presumptive clinical diagnosis of a drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome. The patient was treated with topical betamethasone with good overall response, and initiated the first cycle of chemotherapy before discharge. This case report describes a PTCL-NOS with a concomitant non-lymphoproliferative disease, the challenging diagnostic workup of the two diseases and reinforces the most important features of the lymphoproliferative neoplasm.","PeriodicalId":72274,"journal":{"name":"Archive of clinical cases","volume":"9 4","pages":"140-144"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8b/51/acc-09-04-140.PMC9769073.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10511191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Botulinum toxin as an adjunct for severe Dupuytren's contracture treated with collagenase injections. 肉毒杆菌毒素辅助胶原酶注射治疗严重双膝挛缩。

Archive of clinical cases Pub Date : 2022-01-01 DOI: 10.22551/2022.37.0904.10218

Keith A Denkler, Justin Cheng, Siyou Song, Scott Hansen

{"title":"Botulinum toxin as an adjunct for severe Dupuytren's contracture treated with collagenase injections.","authors":"Keith A Denkler, Justin Cheng, Siyou Song, Scott Hansen","doi":"10.22551/2022.37.0904.10218","DOIUrl":"https://doi.org/10.22551/2022.37.0904.10218","url":null,"abstract":"Even with Dupuytren's proximal interphalangeal joint (PIPJ) contractures successfully released, volar flexor muscle memory can contribute to persistent contracture. We report using botulinum toxin (BoNTA) to the flexor digitorum superficialis muscle (FDS) to reduce flexor tone during recovery. Case Description. Two Collagenase clostridium histolyticum (CCH) injections were given to a patient with a -90° (PIPJ) contracture and a -35° degree distal interphalangeal joint (DIPJ) contracture. At the first CCH injection, 20 μ total of the Botulinum toxin was placed into the FDS muscle. Manipulation occurred at one week. A second injection of CCH followed by manipulation one week later occurred at two months, but no additional BoNTA was given. The final follow-up measurements at 53 months showed a PIPJ of -30° and a DIPJ of 0°. Total active motion improved from 140° to 240°. Outcomes of any treatment for severe Dupuytren's PIPJ contractures of the little finger are unpredictable and are often considered for staged external expansion or even salvage procedures. BoNTA injections weaken flexor tone in tendon repairs and for treating hypertonic muscles after strokes. Conclusion. We hypothesized that BoNTA injection could enhance the outcomes of DC treatment by inhibiting volar flexion forces during the recovery phase. The following case illustrates that using a BoNTA injection may have helped treat a severe PIPJ contracture. BoNTA injections need further research and controlled clinical trials to discover their proper role in Dupuytren's contractures treated via CCH injections, fasciotomies, and fasciectomies.","PeriodicalId":72274,"journal":{"name":"Archive of clinical cases","volume":"9 4","pages":"133-135"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e5/5e/acc-09-04-133.PMC9769080.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10520982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0