Archive of clinical cases最新文献_第3页

A reevaluation of mixed depressive states from the DSM-5- TR perspective: a series of prototypical cases. 从 DSM-5- TR 角度重新评估混合抑郁状态：一系列原型病例。

Archive of clinical cases Pub Date : 2024-04-30 eCollection Date: 2024-01-01 DOI: 10.22551/2024.42.1101.10282

Stefano Pini, Accursio Raia, Giulia Amatori, Benedetta Nardi, Barbara Carpita, Antonio Tundo, Liliana Dell'Osso

{"title":"A reevaluation of mixed depressive states from the DSM-5- TR perspective: a series of prototypical cases.","authors":"Stefano Pini, Accursio Raia, Giulia Amatori, Benedetta Nardi, Barbara Carpita, Antonio Tundo, Liliana Dell'Osso","doi":"10.22551/2024.42.1101.10282","DOIUrl":"https://doi.org/10.22551/2024.42.1101.10282","url":null,"abstract":"Mixed depressive states are defined by the co-presence of depressive and manic symptoms. They represent extremely variable conditions from the point of view of clinical expressiveness and are difficult to recognize, ranging from clear schizophrenic-like psychoses and pseudodemented pictures to subsyndromal psychopathology. At the basis of the extreme variability of depressive pictures with mixed features are the different combinations that depressive and manic symptoms can assume. Furthermore, the intensity of depressive symptoms and manic symptoms, combined, can be variable, a factor that contributes to making the picture even more variable. Each form of mixed depressive state therefore presents its own specific symptomatic characteristics and specific difficulties in differential diagnosis and each form requires a different therapeutic strategy. In this work we have distinguished four possible specific subtypes of mixed depressive states, describing their specific clinical presentation and the therapeutic options most supported by the literature with the aim of contributing to a better recognition of mixed depressive states, to avoid incorrect diagnoses at patient and treatments that are useless if not worsening.","PeriodicalId":72274,"journal":{"name":"Archive of clinical cases","volume":"11 1","pages":"22-28"},"PeriodicalIF":0.0,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11060145/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140867744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring the severity and early onset of familial type 1 diabetes in Romania: genetic and microbiota insights. 探索罗马尼亚家族性 1 型糖尿病的严重性和早期发病情况：遗传和微生物群的启示。

Archive of clinical cases Pub Date : 2024-04-30 eCollection Date: 2024-01-01 DOI: 10.22551/2024.42.1101.10283

Amalia Ioana Arhire, Dorian Sorin Ioacara, Teodora Papuc, Gratiela Gradisteanu Parcalibioru, Simona Fica

{"title":"Exploring the severity and early onset of familial type 1 diabetes in Romania: genetic and microbiota insights.","authors":"Amalia Ioana Arhire, Dorian Sorin Ioacara, Teodora Papuc, Gratiela Gradisteanu Parcalibioru, Simona Fica","doi":"10.22551/2024.42.1101.10283","DOIUrl":"https://doi.org/10.22551/2024.42.1101.10283","url":null,"abstract":"Type 1 diabetes mellitus (T1DM) is a chronic condition characterized by pancreatic autoimmunity and destruction of the insulin producing beta-cells. The risk of familial type 1 diabetes (FT1DM) is greater in families with paternal T1DM. The children with paternal FT1DM have a more severe form of the disease with diabetic ketoacidosis. Three families with FT1DM, out of which two with paternal diabetes and daughters diagnosed with this disease, and one family with sibling FT1DM were evaluated between 2019-2021 in the Pediatric Diabetes and the Diabetes, Nutrition and Metabolic Departments of a tertiary hospital. Clinical, biological, and genetic evaluations were performed, together with an assessment of the gastrointestinal microbiota. The Romanian children with FT1DM had a more severe onset, a median of age at onset of 9 years old and a genetic predisposition with positive HLA DR3/R4, DQB1*02:01. The protecting allele, DPB1*04:01, was found only in the siblings with FT1DM. A gastrointestinal dysbiosis, characterized by pro-inflammatory bacteria, with high levels of Enterobacteriaceae and Candida, was observed in the gut microbiota. This is the first case series of FT1DM in Romanian patients that shows the presence of genetic determinants but also a pathological microbiota which may determine a more severe and an early-age onset of disease.","PeriodicalId":72274,"journal":{"name":"Archive of clinical cases","volume":"11 1","pages":"29-33"},"PeriodicalIF":0.0,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11060146/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140873822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recurrent diffuse alveolar hemorrhage and extracorporeal membrane oxygenation utilization in a hematopoietic stem cell transplant patient with Hunter's syndrome. 一名亨特综合征造血干细胞移植患者的复发性弥漫性肺泡出血和体外膜氧合的使用。

Archive of clinical cases Pub Date : 2024-04-30 eCollection Date: 2024-01-01 DOI: 10.22551/2024.42.1101.10281

Nasreen Noor, Gene Peir, Ásdís Finnsdóttir Wagner, Jay Rilinger, Jenna Miller

引用次数: 0

A unique case of indolent microscopic polyangiitis in an elderly gentleman: a case report and brief review. 一名老年男性患惰性显微镜下多血管炎的独特病例：病例报告和简要回顾。

Archive of clinical cases Pub Date : 2023-12-28 eCollection Date: 2023-01-01 DOI: 10.22551/2023.41.1004.10276

Clement Tan, Jithmy Perara, Pranav Kumar

引用次数: 0

Paget-Schroetter syndrome: the importance of early detection and effective surgical intervention. Paget-Schroetter 综合征：早期发现和有效手术干预的重要性。

Archive of clinical cases Pub Date : 2023-12-28 eCollection Date: 2023-01-01 DOI: 10.22551/2023.41.1004.10275

Sofija Pejkova, Darko Aleksovski, Sara Hadjitrifon, Sofija Tusheva, Gordana Georgieva, Blagoja Srbov, Oskar C Aszmann

{"title":"Paget-Schroetter syndrome: the importance of early detection and effective surgical intervention.","authors":"Sofija Pejkova, Darko Aleksovski, Sara Hadjitrifon, Sofija Tusheva, Gordana Georgieva, Blagoja Srbov, Oskar C Aszmann","doi":"10.22551/2023.41.1004.10275","DOIUrl":"10.22551/2023.41.1004.10275","url":null,"abstract":"Paget-Schroetter syndrome (PSS) is relatively rare condition of thoracic outlet syndrome characterized by thrombosis or blood clot formation in the subclavian vein. Due to the non-specific symptoms and low incidence rate, PSS is frequently missed by medical professionals, and as such it often leads to wrong diagnosis and untreated patients. We present the case of a 30-year-old CrossFit trainer who developed a thrombosis of the subclavian vein. Initially, the patient consulted an internist after experiencing swelling in the right shoulder region and discoloration of the right upper extremity. Angiography revealed occlusion of the subclavian vein and anticoagulant therapy was prescribed. For more than a year, the patient's symptoms remained unchanged, and the subclavian vein occlusion persisted. Venography suspected effort thrombosis of the subclavian vein. The patient underwent surgery for decompression of the subclavian vein. After six months, results from post-operative computed tomography angiography showed that venous flow was fully restored and no pathology of the venous vessel wall could be demonstrated. This report aims to increase awareness of PSS among medical professionals, leading to earlier diagnosis and adequate clinical-surgical management.","PeriodicalId":72274,"journal":{"name":"Archive of clinical cases","volume":"10 4","pages":"200-204"},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10754040/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139059239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bullosis diabeticorum in a morbidly obese woman in Haiti. 海地一名病态肥胖妇女的糖尿病大疱症。

Archive of clinical cases Pub Date : 2023-12-28 eCollection Date: 2023-01-01 DOI: 10.22551/2023.41.1004.10274

Axler Jean Paul, Rebecca St Louis, Adonai Aly Isaac Julien, Frednel Florvil, Wendell Blaise

{"title":"Bullosis diabeticorum in a morbidly obese woman in Haiti.","authors":"Axler Jean Paul, Rebecca St Louis, Adonai Aly Isaac Julien, Frednel Florvil, Wendell Blaise","doi":"10.22551/2023.41.1004.10274","DOIUrl":"10.22551/2023.41.1004.10274","url":null,"abstract":"Bullosis diabeticorum is a rare skin complication of diabetes mellitus, characterized by sudden onset bullous lesions with no history of trauma. It predominantly affects men and has an acral asymmetric presentation. Here, we report a case of bullous disease in a diabetic patient with morbid obesity, the first described in Haiti. A 40-year-old woman, with a strong history of diabetic for five years, poorly controlled and morbidly obese presented to our emergency for bullosis lesions in her limb. She had a prior presentation about two years ago and, approximately a week before this actual presentation, the same symptomatology occurred suddenly without any trauma. After evaluation and screening, the diagnosis of bullosis diabeticorum was kept. She was initially treated with antibiotics due to signs of superinfection. However, as soon as the symptoms improved, antibiotics were discontinued. An antiseptic lotion and topical antibiotic, neomycin, were used along with daily dressings. About a week after, her blood glucose came to control, signs of infection disappeared as did the bullous lesions and surgical evaluation was performed to ensure proper wound evolution. She was educated by a nutritionist, and our team emphasized the importance of regular follow-up at the hospital. Diabetic bullous disease is very rare and easy to confuse with other diabetic skin complications. A good clinical history is essential to make the diagnosis, and management requires good therapeutic education to avoid the burdensome complications of diabetes.","PeriodicalId":72274,"journal":{"name":"Archive of clinical cases","volume":"10 4","pages":"196-199"},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10754039/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139059238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Superscan on ⁶⁸Ga PSMA PET/CT in patients with metastatic prostate carcinoma: A case series. 68Ga PSMA PET/CT 对转移性前列腺癌患者的超级扫描：病例系列。

Archive of clinical cases Pub Date : 2023-12-28 eCollection Date: 2023-01-01 DOI: 10.22551/2023.41.1004.10267

Daniel Felipe Galindo Cortes, Helen Mejia Efeer, Sandra Caro Perdomo, Nathalie Hernandez Hidalgo

{"title":"Superscan on 68Ga PSMA PET/CT in patients with metastatic prostate carcinoma: A case series.","authors":"Daniel Felipe Galindo Cortes, Helen Mejia Efeer, Sandra Caro Perdomo, Nathalie Hernandez Hidalgo","doi":"10.22551/2023.41.1004.10267","DOIUrl":"10.22551/2023.41.1004.10267","url":null,"abstract":"Prostate cancer is the second most common malignancy in men worldwide, with a good prognosis when is detected and treated in early stages, but, when it presents progression to castration-resistant metastatic prostate cancer, most of the cases will have bone metastasis, decreasing the quality of life and life expectancy. For the evaluation of the disease in the routinary clinical practice, 68Ga-PSMA PET/CT, among others is a valuable tool for the evaluation of the disease extension. 68Ga-PSMA PET/CT detects the presence of PSMA receptor in the tumoral tissue, but also has physiologic uptake in certain organs, such as liver, spleen, intestine, kidneys, lacrimal and salivary glands. Total or partial absence of uptake in those organs is rare and may be due to a high metastatic tumor burden, a phenomenon originally described in bone scintigraphy as super scan. We describe a case series of seven patients with prostate cancer from the National Institute of Cancerology in Colombia, in which a super scan pattern was found in the evaluation with 68Ga-PSMA PET/CT, proposing the suppression of uptake in the intestine, liver, spleen, lacrimal and salivary glands as the main criteria for its definition, and showing that renal uptake persists in most cases, considering that, unlike the super scan in conventional bone scintigraphy, this is not a criterion necessary for its definition in the study with 68Ga-PSMA.","PeriodicalId":72274,"journal":{"name":"Archive of clinical cases","volume":"10 4","pages":"164-170"},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10753930/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139059240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rare case of mortality after hemorrhagic property of esthesioneuroblastoma. 雌性神经母细胞瘤出血后死亡的罕见病例。

Archive of clinical cases Pub Date : 2023-12-14 eCollection Date: 2023-01-01 DOI: 10.22551/2023.41.1004.10269

Todd Furr, Brandon Grodman, Jeremy Heffernan

{"title":"Rare case of mortality after hemorrhagic property of esthesioneuroblastoma.","authors":"Todd Furr, Brandon Grodman, Jeremy Heffernan","doi":"10.22551/2023.41.1004.10269","DOIUrl":"https://doi.org/10.22551/2023.41.1004.10269","url":null,"abstract":"Esthesioneuroblastoma is a tumor arising from olfactory neuroepithelium with an incidence of four per million. This case presents a rare nasal cavity neoplasm with hemorrhagic properties that may lead to significant sequelae. We present a 69-year-old male patient who presented with worsening altered mental status over the past 6-7 months. His Glasgow coma scale was a nine, showing a large mass centered at the cribriform plate with extension intracranially, sinonasal cavity, and bilateral orbits on diagnostics. Bifrontal craniotomy was performed one day after admission with resection of the tumor in the cranial fossa and intranasally, and decompression of the brainstem, frontal lobes, and third ventricle. After surgery, the patient was managed in the intensive care unit but continued to deteriorate. He was confirmed to have no meaningful brain activity and eventually deceased seven days after admission. Depending on the tumor stage, esthesioneuroblastoma can have a favorable prognosis with proper therapies. Different surgical techniques for ENB lead to the question of which therapeutic modality is the best because of the tumor's gross hemorrhagic properties. With adjunctive radiation therapy and/or chemotherapy, more research can bring light to proper surgical techniques.","PeriodicalId":72274,"journal":{"name":"Archive of clinical cases","volume":"10 4","pages":"175-178"},"PeriodicalIF":0.0,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10719983/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138800529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Complete major pancreatic duct disruption complicated by pancreatico-atmospheric fistula following blunt upper abdominal trauma. 上腹部钝挫伤后完全性大胰管断裂并发胰胆管瘘。

Archive of clinical cases Pub Date : 2023-12-14 eCollection Date: 2023-01-01 DOI: 10.22551/2023.41.1004.10270

Shafic Abdulkarim, Saud Aldeghaither, Dan L Deckelbaum

引用次数: 0

Dextrocardia with Situs Solitus in a Neonate - an Overview. 新生儿孤坐性右心室缺血 - 综述。

Archive of clinical cases Pub Date : 2023-12-14 eCollection Date: 2023-01-01 DOI: 10.22551/2023.41.1004.10268

Nelson Franqui-Rios, Yasmin Garcia, Leened Velazquez-Garcia

引用次数: 0