Andes pediatrica : revista Chilena de pediatria最新文献

{"title":"[Correlation between serum ferritin, erythrocyte and hemoglobin indices in infants living at 3400 m altitude].","authors":"Wilfredo Villamonte-Calanche, David Orccosupa-Quispe, Fiorella Mendoza-Cabrera, Erick Flores-Gonzales, Lynda Cari-Avalos, Ronny Breibat-Timpo","doi":"10.32641/andespediatr.v94i6.4486","DOIUrl":"10.32641/andespediatr.v94i6.4486","url":null,"abstract":"<p><p>Anemia (An) is a public health problem in South America, with iron deficiency (ID) as the main cause. In high-altitude cities, hypobaric hypoxia causes an increase in hemoglobin (Hb) levels in residents. For the diagnosis of An, Hb is measured, which is modified after erythrocyte indices (EI) measurements. There is evidence that there is an overestimation of the prevalence of An at high altitudes.</p><p><strong>Objective: </strong>To correlate serum ferritin (SF) with Hb and EI, and to determine the Hb cut-off point for predicting ID in 6-month-old infants at 3400 m of altitude.</p><p><strong>Subjects and method: </strong>128 infants aged 6 months at 3400 m altitude were evaluated. The SF was considered an independent variable. IE and Hb were the dependent variables. The An in the infant was defined with an Hb < 13.4 g/dl. The DH was defined by FS <12 ug/dL. Data were processed in SPSS® version 25. Spearman correlation was used for bivariate analysis. The ROC curve was constructed to determine the Hb cut-off point for ID.</p><p><strong>Results: </strong>The highest correlation of SF was observed with mean corpuscular hemoglobin (MCH), rho = 0.449 (p < 0.001), and mean corpuscular volume (MCV) rho= 0.423 (p < 0.001). The Hb cut-off point according to SF, defining ID was 12.15 g/dL (ROC curve: 0.704; 95% CI: 0.597-0.811; p < 0.001).</p><p><strong>Conclusion: </strong>MCV and MCH showed a better correlation with SF. The cubic and logarithmic models were the ones that best represented these relationships, respectively. Hb < 12.15 g/dL allows diagnosing ID in 6-month-old infants at 3400 m altitude.</p>","PeriodicalId":72196,"journal":{"name":"Andes pediatrica : revista Chilena de pediatria","volume":"94 6","pages":"705-712"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Disparities in the use of mental health services of adolescents in Chile].","authors":"Marcia Salinas-Contreras, Belén Vargas, Marcelo A Crockett, Vania Martinez","doi":"10.32641/andespediatr.v94i6.4637","DOIUrl":"10.32641/andespediatr.v94i6.4637","url":null,"abstract":"<p><strong>Objective: </strong>To examine disparities in the use of mental health services (MHS) in adolescents according to sociodemographic factors.</p><p><strong>Subjects and method: </strong>2,022 adolescents aged 13-19 years in Santiago, Chile, participated in the study. Between April and May 2008, they answered a self-report survey that assessed lifetime (history of treatment for depression) and current (psychological or pharmacological treatment) use of MHS, sociodemographic variables, and psychopathology as symptoms of depression, symptoms of generalized anxiety disorder, and risk of problematic substance use. Data were analyzed using logistic regression.</p><p><strong>Results: </strong>16.5% of participants reported lifetime use of MHS due to depression, 9.7% were on current psychological treatment, and 2.7% were on current pharmacological treatment. Among those meeting criteria for a mental health problem, only 14.9% to 18.9% were currently on treatment. Males, younger participants, and those who had immigrants' parents reported lower lifetime use of MHS due to depression. Those with parents with 9 to 12 years of education and who had immigrants' parents reported lower current MHS use. Youth not living with both parents reported higher lifetime and current MHS use.</p><p><strong>Conclusions: </strong>We observe a high treatment gap in those with mental health needs as well as differences in MHS use based on socio-demographic variables. These results may be useful for planning interventions that favor access to and use of MHS, especially in the most disadvantaged groups of adolescents.</p>","PeriodicalId":72196,"journal":{"name":"Andes pediatrica : revista Chilena de pediatria","volume":"94 6","pages":"681-688"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Risk factors in the delay of treatment of childhood tuberculosis in a Peruvian Hospital].","authors":"Gabriela Cartolin P, Consuelo Luna M","doi":"10.32641/andespediatr.v94i6.4080","DOIUrl":"10.32641/andespediatr.v94i6.4080","url":null,"abstract":"<p><p>Childhood tuberculosis (c-TB) continues to be one of the causes of morbidity and mortality in children, but there is still little information on the delay in the initiation of specific treatment.</p><p><strong>Objective: </strong>To determine the risk factors associated with delayed initiation of tuberculosis (TB) treatment in children under 15 years of age.</p><p><strong>Patients and method: </strong>Case-control study. Patients <15 years of age with a diagnosis of childhood pulmonary tuberculosis (c-PTB) with delayed treatment initiation >24 hours were included. Clinical and epidemiological variables were evaluated: age, gender, guardian's education, poverty level, origin, family history of TB, altered imaging findings, symptomatic, PPD >10mm, histology, bacteriology, resistance to treatment, and healthcare network. Bi and multivariate logistic regression analysis was performed, through which odds ratios were calculated.</p><p><strong>Results: </strong>We evaluated 116 patients with c-PTB with a delayed initiation of specific treatment of more than 24 hours, and 264 with start of treatment in the first 24 hours. The delay in anti-tuberculosis treatment had a median of 3 days with an interquartile range of 2 to 7 days. The patient with the least educated guardian had a delay in treatment initiation with an odds ratio of 7.47 (95%CI: 4.13 - 13.52). Belonging to the healthcare network A of Callao decreased the probability of having tuberculosis by 0.224 times (95%CI:0.11 - 0.46).</p><p><strong>Conclusion: </strong>Incomplete education level of the guardian is a risk factor associated with delayed initiation of c-PTB treatment in children under 15 years of age while belonging to the Callao healthcare network A is a factor that decreases the risk in the group under study.</p>","PeriodicalId":72196,"journal":{"name":"Andes pediatrica : revista Chilena de pediatria","volume":"94 6","pages":"698-704"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Long-term follow-up data of patients with Multiple Pituitary Hormone Deficiency].","authors":"Aysegul Elvan-Tuz, Elvan Bayramoglu, Semra Cetinkaya","doi":"10.32641/andespediatr.v94i6.4680","DOIUrl":"10.32641/andespediatr.v94i6.4680","url":null,"abstract":"<p><p>The deficiency of two or more pituitary hormones is called multiple pituitary hormone deficiencies (MPHD). Its prevalence is estimated to be about 1/8,000 worldwide.</p><p><strong>Objective: </strong>To present the diagnosis processes, clinical findings, and long-term follow-up of patients with MPHD.</p><p><strong>Patients and method: </strong>Between 1999 and 2015, patients diagnosed with MPHD were evaluated. Clinical presentation, anthropometry, imaging studies, and clinical evolution were analyzed. Hormone status was evaluated, including growth hormone (GH), thyroid-stimulating hormone (TSH), adrenocorticotropic hormone (ACTH), follicle-stimulating hormone/luteinizing hormone (FSH/LH), and prolactin (PRL). Data were assessed using the student's t-test and the Mann-Whitney U test. Spearman's correlation was used for correlations. A p-value < 0.05 was considered statistically significant.</p><p><strong>Results: </strong>Forty-five patients were included; 55.6% were male, the mean age at presentation was 5.6 ± 3.9 (0-14.4) years, and the median bone age was 3.5 ± 2.3 (0.5-11) years. At admission, GH deficiency was found in 88.9% of the cases, TSH deficiency in 77.8%, ACTH deficiency in 33.3%, FSH/LH deficiency in 22.2%, and PRL deficiency in 17.8%. During the follow-up, 62% of the cases added other hormone deficiencies. The mean follow-up period was 9.18 ± 3.6 (3.02-17.2) years.</p><p><strong>Conclusion: </strong>Patients with MPHD have very different clinical presentations, with GH and TSH deficiency being the most common in this study. Additional hormonal deficiencies can occur even years after the initial diagnosis and our results demonstrate that genetic height potential is achieved with GH treatment.</p>","PeriodicalId":72196,"journal":{"name":"Andes pediatrica : revista Chilena de pediatria","volume":"94 6","pages":"689-697"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[In response to: \"The beginnings of pediatrics education in Chile and the foundation of children's hospitals\". Foundation of children's hospitals and pediatric milestones beyond Santiago].","authors":"Cristián Sotomayor Fahrenkrog","doi":"10.32641/andespediatr.v94i6.4922","DOIUrl":"10.32641/andespediatr.v94i6.4922","url":null,"abstract":"","PeriodicalId":72196,"journal":{"name":"Andes pediatrica : revista Chilena de pediatria","volume":"94 6","pages":"744-746"},"PeriodicalIF":0.5,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Prenatal presentation of pleuropulmonary blastoma associated to DICER1 syndrome: differential diagnosis of congenital pulmonary malformation].","authors":"Catalina Catán Valenzuela, Paula Vargas Innocenti, Aquiles Hachim Gutierrez, Pablo Jorquera Pinto, Ximena Claverie Ramos, Ruby Carrasco Gaete, Álvaro Flores Catalán, Pablo Alarcon Arias, José Campos Varas","doi":"10.32641/andespediatr.v94i6.4663","DOIUrl":"10.32641/andespediatr.v94i6.4663","url":null,"abstract":"<p><p>Pleuropulmonary blastoma (PPB) is the most common pediatric malignant primary lung tumor. It's associated with the DICER1 gene pathogenic germline variants. Antenatal presentation is infrequent and poses a challenge in the differential diagnosis of congenital pulmonary airway malformation (CPAM).</p><p><strong>Objective: </strong>to report a case of unusual presentation of PPB associated with DICER1 syndrome and to describe the difficulty in differentiating it from CPAM.</p><p><strong>Clinical case: </strong>Male patient with prenatal diagnosis of hypervascular left lung lesion, with mediastinal shift and progressive growth, initially interpreted as CPAM. He was born at 38 weeks, requiring transitory treatment with positive pressure due to ventilatory impairment. A CT scan with contrast showed a large multilocular cystic mass containing air causing mass effect, requiring open left upper lobectomy. Histology results were compatible with type I PPB, with negative margins, and positive genetic study for DICER1 syndrome. Seven weeks post-resection, an aerial image was detected in the upper left side of the chest, with progressive growth, requiring a new tumor resection and upper segmentectomy, with biopsy corresponding to recurrence of type I PPB with negative margins. He received adjuvant treatment with chemotherapy, with follow-up for 2 years, remaining asymptomatic, without recurrence, and with negative screening for other neoplasms associated with DICER1 syndrome. Among the family history, the mother had papillary thyroid cancer and tested positive for the mutation.</p><p><strong>Conclusion: </strong>PPB is a rare cancer, difficult to distinguish from CPAM, especially in its antenatal presentation. Nowing its association with DICER1 syndrome and performing a genetic study are key to the early detection of BPP and the search for other tumors associated with the syndrome.</p>","PeriodicalId":72196,"journal":{"name":"Andes pediatrica : revista Chilena de pediatria","volume":"94 6","pages":"729-735"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validación psicométrica de Pauta de Clasificación de Complejidad Médica de niños, niñas y adolescentes con Necesidades Especiales de Atención en Salud","authors":"Ana Cabezas T., Carolina Rivera L., Luis Sarmiento L.","doi":"10.32641/andespediatr.v94i5.4522","DOIUrl":"https://doi.org/10.32641/andespediatr.v94i5.4522","url":null,"abstract":"Los niños, niñas y adolescentes con Necesidades Especiales de Atención en Salud (NANEAS), presentan un uso intensivo de recursos por parte de los servicios de salud y demandan un gran nivel de coordinación en la integración de estos servicios, las comunidades y familias. El comité de NANEAS de la SOCHIPE junto a otros expertos generaron una Pauta de Clasificación de Complejidad para otorgar una asignación de recursos adecuada a la necesidad de los casos a través de la Red Asistencial. Objetivo: Realizar una validación de constructo de la Pauta de Clasificación de Complejidad. Sujetos y Método: Con una muestra de 488 niños NANEAS a quienes se aplicó la Pauta de Clasificación, se realizó un análisis de confiabilidad del instrumento, además de un análisis factorial exploratorio y confirmatorio. Resultados: La Pauta de Clasificación obtuvo un Alfa de Cronbach estandarizado de 0,87, sin embargo, los estadísticos de ajuste de modelo RMSEA, TLI y CFI resultaron bajo lo esperado. El coeficiente MI sugirió la eliminación de 9 ítems, a partir de lo cual se generó una Pauta resumida de 11 ítems y tres dimensiones que presentó un RMSEA de 0,60; TLI de 0,970 y CFI de 0,977. Conclusión: El estudio permite contar con una Pauta de Clasificación de Complejidad resumida para niños NANEAS, con buenas propiedades psicométricas, rápida aplicación y fácil interpretación, para la aplicación en la Red Asistencial de Salud.","PeriodicalId":72196,"journal":{"name":"Andes pediatrica : revista Chilena de pediatria","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135824122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"La extubación durante la noche no se asocia con su fracaso en pacientes pediátricos de Unidad de Cuidados Intensivos: Estudio de cohorte retrospectivo","authors":"Maybreet Ibarra V., Francisca Andrades E., María Satta S., Franco Díaz R., Alejandro Donoso F.","doi":"10.32641/andespediatr.v94i5.4583","DOIUrl":"https://doi.org/10.32641/andespediatr.v94i5.4583","url":null,"abstract":"Poco es conocido sobre la hora del día y carácter de éste (hábil/no hábil) en que se efectúa la extubación, y si durante la noche esta es segura. Objetivo: describir la frecuencia de extubación nocturna (EN) y en día no hábil (ENH). Adicionalmente determinar la asociación entre éstas y resultados clínicos. Pacientes y Método: Estudio de cohorte retrospectivo de pacientes menores de 18 años quienes recibieron ventilación mecánica (VM) invasiva y se efectuó un intento extubación en una Unidad de Paciente Crítico Pediátrico (UPCP) médico quirúrgica de alta complejidad entre el 01/01/2018 al 31/12/2021. Exposición primaria: EN, la cual fue definida como la realizada entre 20:01 - 8:00 horas. Se evaluó su asociación con fracaso de extubación (FE), duración de VM invasiva y tiempo de esta- día en la UPCP.Resultados: 146 pacientes fueron incluidos (58,9% hombres, edad 1,14 (0,25 - 5,5) años). En el 17,8% se efectuó EN. La extubación nocturna no se asoció con FE como tampoco el día de extubación. El FE fue 3,8% en EN y 5% en la extubación diurna (ED) (p = 0,80). La duración de la VM invasiva fue menor en EN que ED (48 (24-73,5) vs. 72 (48-96) h, p = 0,02). Conclusiones: La EN no se asoció con FE. Los pacientes con EN tuvieron menor duración de VM invasiva, y ésta última se asoció con FE. La retirada de la VM invasiva debe ser considerada en la primera oportunidad y estar determinada por factores clínicos, más que por la hora del día.","PeriodicalId":72196,"journal":{"name":"Andes pediatrica : revista Chilena de pediatria","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135888188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitamina D en pediatría tras el fin del confinamiento domiciliario: estudio prospectivo","authors":"Carlota Aparicio Fernández de Gatta, Haydee Expósito de Mena, Olga González Calderón, Jesús Alonso Díaz, Aránzazu Hernández-Fabián, Ricardo Torres Peral","doi":"10.32641/andespediatr.v94i5.4538","DOIUrl":"https://doi.org/10.32641/andespediatr.v94i5.4538","url":null,"abstract":"El confinamiento domiciliario durante el inicio de la pandemia por SARS-CoV-2 disminuyó la exposición solar, principal fuente de vitamina D del organismo.Objetivo: evaluar la repercusión del confinamiento por SARS-CoV-2 en los niveles de 25-hidroxivitamina D (25-OH-VD) de una población pediátrica.Pacientes y Método: Estudio observacional en una población pediátrica española entre junio y octubre de 2020. Se determinaron los niveles de 25-OH-VD mediante electroquimioluminiscencia y se recogieron diferentes variables relacionadas (antropometría, sexo, fototipo de piel, fecha, nivel de calcio, fósforo inorgánico, paratohormona y fosfatasa alcalina). El acompañante del niño contestó una encuesta que incluía los siguientes aspectos: acceso al aire libre en la casa donde se realizó el confinamiento; horas de sol al día que recibía el niño tras el fin del confinamiento; utilización habitual de protector solar con la exposición al aire libre; fototipo de piel del niño; tipo de leche que toma habitualmente el niño; administración de suplementos de 25-OH-VD y, si los toma, dosis y adherencia al tratamiento. Resultados: Participaron 123 niños, media de edad de 8,15 años (IC95% 7,52-8,79), 56,1% sexo femenino. La mediana de 25-OH-VD fue 27,70 ng/ml [RIC 22,75-33,60], el 14% presentó insuficiencia de 25-OH-VD (< 20 ng/ml). Los niveles de 25-OH-VD presentaron una pendiente de correlación ascendente según la fecha se alejaba del final del confinamiento (Rho 0,467; p < 0,001), relacionándose con las horas de sol (Rho 0,368; p < 0,001). Los niveles de 25-OH- VD fueron mayores en los pacientes con fotoprotección (mediana 29,9 vs 23,5 ng/ml, p = 0,005), habiendo diferencias en función del fototipo de piel (p = 0,032); pero no se relacionaron con la edad, z-scores de peso, talla e índice de masa corporal, ni con la presencia de balcón o jardín en el domicilio. Conclusión: La tasa de insuficiencia de 25-OH-VD al final de confinamiento no fue mayor que en estudios previos. Los niveles de 25-OH-VD aumentaron de forma progresiva, en relación con las horas de exposición solar y con los meses de verano. Curiosamente, los niveles de 25-OH-VD fueron mayores en los niños con fotoprotección.","PeriodicalId":72196,"journal":{"name":"Andes pediatrica : revista Chilena de pediatria","volume":"875 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135888452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Xantogranuloma juvenil gigante y ulcerado: una presentación atípica en lactantes","authors":"Sofía Guelfand Warnken, Ximena Fajre Wipe, Claudia Suarez Aldunate, Rosario Aguero Ureta, Alex Castro Médez","doi":"10.32641/andespediatr.v94i5.4673","DOIUrl":"https://doi.org/10.32641/andespediatr.v94i5.4673","url":null,"abstract":"El xantogranuloma juvenil (XGJ) gigante es una variante infrecuente de XGJ, se caracteriza por una lesión mayor a 2 cm de diámetro. Generalmente se presenta como placa y rara vez, como nódulo ulcerado. Objetivo: Reportar dos casos de XGJ de presentación atípica, destacando la importancia de considerarlos dentro del diagnóstico diferencial de tumores ulcerados de gran tamaño en lactantes. Casos Clínicos: Caso 1: Lactante masculino sano, consultó por nódulo inguinal eritematoso indurado de 2,6 cm con ulceración central, presente desde los 2 meses de edad, de crecimiento rápido y progresivo. Se realizó biopsia incisional cuya histología fue compatible con XGJ. Se descartó compromiso oftalmológico. Se realizó extirpación quirúrgica excisional por su impacto funcional y preocupación de los cuidadores. Evolucionó favorablemente sin recidiva local a 4 años de seguimiento. Caso 2: Lactante masculino sano consultó por nódulo escapular derecho de 2,4 cm, de consistencia firme, con costra central, presente desde el mes de vida, de crecimiento rápido y progresivo. El estudio histológico incisional fue compatible con XGJ. Se descartó compromiso oftalmológico y en 18 meses de seguimiento clínico seriado, presentó disminución progresiva del tamaño de la lesión. Conclusiones: Los casos presentados destacan la importancia de considerar el XGJ dentro del diagnóstico diferencial de tumores cutáneos ulcerados de gran tamaño en lactantes. Frente a presentaciones clínicas atípicas, el estudio histológico ayuda a confirmar el diagnóstico. Dado el pronóstico favorable, se aconseja el seguimiento clínico periódico y, en casos excepcionales, se puede optar por tratamientos quirúrgicos o ablativos.","PeriodicalId":72196,"journal":{"name":"Andes pediatrica : revista Chilena de pediatria","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135823767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}