American journal of clinical and experimental immunology最新文献_第9页

Bile duct injury outcomes following cholecystectomy: a cross sectional study. 胆囊切除术后胆管损伤的结果:一项横断面研究。

American journal of clinical and experimental immunology Pub Date : 2020-06-15 eCollection Date: 2020-01-01

Sepehr Eslami, Lotfallah Abedini, Nazanin Vahedi Nouri, Mehdi Rabiee, Milad Kabiri Samani

{"title":"Bile duct injury outcomes following cholecystectomy: a cross sectional study.","authors":"Sepehr Eslami, Lotfallah Abedini, Nazanin Vahedi Nouri, Mehdi Rabiee, Milad Kabiri Samani","doi":"","DOIUrl":"","url":null,"abstract":"Background: Considering the importance of the repairing time in patients with biliary duct injury, the aim of this study was to evaluate the outcomes of patents with bile duct injury following cholecystectomy.Methods: In this cross sectional study that was conducted on 64 patients with bile duct injury following cholecystectomy was referred to Shafa hospital in Tehran-Iran during 2010-2019 due to repair of biliary duct. Then patients were divided into two groups based on early and late referring time after bile duct injury, the postoperative outcomes were evaluated in two groups.Results: The alanine transaminase (ALT) and the aspartate aminotransferase (AST) in the late group were significantly higher than the early group. There were significant differences between the two groups based on the results of endoscopic retrograde cholangiopancreatography (ERCP) and magnetic resonance cholangiopancreatography (MRCP) (P < 0.05). The frequency of bile duct dilatation, cholangitis and itching in late group were significantly higher than early group, also the frequency of uncomplicated outcome in the early group were significantly more than late group (P < 0.05).Conclusion: The postoperative complication of biliary duct injury reduced, if patients diagnosed and referred at the same early stages (early referral).","PeriodicalId":72163,"journal":{"name":"American journal of clinical and experimental immunology","volume":"9 3","pages":"53-57"},"PeriodicalIF":0.0,"publicationDate":"2020-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364374/pdf/ajcei0009-0053.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38188117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Incidence of low back pain and sacroiliitis in military families with acne vulgaris under isotretinoin therapy. 接受异维A酸治疗的患有寻常型痤疮的军人家庭中腰痛和骶髂关节炎的发病率。

IF 1.4

American journal of clinical and experimental immunology Pub Date : 2020-04-15 eCollection Date: 2020-01-01

Alahyar Taheri, Sadegh Sabouhi, Farzaneh Farazmand

{"title":"Incidence of low back pain and sacroiliitis in military families with acne vulgaris under isotretinoin therapy.","authors":"Alahyar Taheri, Sadegh Sabouhi, Farzaneh Farazmand","doi":"","DOIUrl":"","url":null,"abstract":"Background: Acne vulgaris is a common complication that patients referred to dermatologist, also there are medications to manage of this such as isotretinoin, and incidence of low back pain in these patients is more than general population, so in this study we aimed to evaluate of Incidence of low back pain and sacroiliitis in military families with acne vulgaris under isotretinoin therapy.Methods: This cross-sectional study was performed on 113 acne vulgaris patients treated with isotretinoin (at least 3 months) referred to dermatology clinic of Imam Reza Hospital of Army Medical Sciences, Tehran, Iran during 2018 to 2019. All data of patients such as dosage and duration of medication, severity of acne, incidence of low back pain, sacroiliitis and inflammatory back pain and lab data were recorded.Results: 54% of patients had lethargy, 41.6% had myalgia and 46.9% had low back pain. Of the patients with low back pain, 54.7% had inflammatory low back pain and 45.3% had mechanical low back pain. 29 cases had inflammatory low back pain, 5 cases had sacroiliitis and one case had positive RF, the means of ESR, CRP and ANA were 19.01 ± 12.74 Mm/hr, 3.43 ± 1.27 Mg/litr and 1.31 ± 0.90, respectively.Conclusion: In patients with acne vulgaris under isotretinoin therapy much attention must be given regarding to sacroiliitis and rheumatoid diseases especially when symptoms such as low back pain are present.","PeriodicalId":72163,"journal":{"name":"American journal of clinical and experimental immunology","volume":"9 2","pages":"6-9"},"PeriodicalIF":1.4,"publicationDate":"2020-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218680/pdf/ajcei0009-0006.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37946765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antibacterial activity of betle leaf (Piper betle l.) extract on inhibiting Staphylococcus aureus in conjunctivitis patient. 槟榔叶提取物对结膜炎患者金黄色葡萄球菌的抑菌作用。

American journal of clinical and experimental immunology Pub Date : 2020-02-25 eCollection Date: 2020-01-01

Rodiah Rahmawaty Lubis, Marlisa, Dian Dwi Wahyuni

{"title":"Antibacterial activity of betle leaf (Piper betle l.) extract on inhibiting Staphylococcus aureus in conjunctivitis patient.","authors":"Rodiah Rahmawaty Lubis, Marlisa, Dian Dwi Wahyuni","doi":"","DOIUrl":"","url":null,"abstract":"The aim of this study is to determine the antibacterial activity of Piper betle L. leaf extract on inhibiting Staphylococcus aureus in conjunctivitis patient. This study follows a post-test only group experimental design. Antibacterial activities of five Piper betle L. extract concentrations (0.5%, 1%, 1.5%, 2%, 2.5%, and 3%) against Staphylococcus aureus were evaluated by agar well diffusion method. The negative control group (P-) was treated with standard 10% DMSO solution, the positive control group (P+) with ceftriaxone. The diameters of clear zone surrounding the well were analyzed with Kruskal-Wallis test and showed that in between 1% and 1.5%; 1.5% and 2%; 2% and 2.5%; 2.5% and 3% concentrations do not show a significant difference but in between 0.5% and 1%; 0.5% and 1.5%; 0.5% and 2%; 0.5% and 2.5%; 0.5% and 3%; 1% and 2%; 1% and 2.5%; 1% and 3%; 1.5% and 2.5%; 1.5% and 3%; 2% and 3% concentrations, Piper betle L. leaf extract shows a significant difference on inhibiting the growth of Staphylococcus aureus. In conclusion the results obtained show that that Piper betle L. leaf extract has a significant potential use as an antibacterial agent.","PeriodicalId":72163,"journal":{"name":"American journal of clinical and experimental immunology","volume":"9 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076289/pdf/ajcei0009-0001.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37769988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comprehensive clinical and immunological features of 62 adult patients with selective primary IgM deficiency. 62例成人选择性原发性IgM缺乏症的综合临床和免疫学特征

American journal of clinical and experimental immunology Pub Date : 2019-12-25 eCollection Date: 2019-01-01

Dayna Lee Lucuab-Fegurgur, Sudhir Gupta

{"title":"Comprehensive clinical and immunological features of 62 adult patients with selective primary IgM deficiency.","authors":"Dayna Lee Lucuab-Fegurgur, Sudhir Gupta","doi":"","DOIUrl":"","url":null,"abstract":"Selective IgM Deficiency (SIgMD) is a recently incorporated disorder in the classification of primary immunodeficiency diseases. The purpose of this study was to present detailed clinical and immunological features in a cohort of 62 adult patients with SIgMD. A retrospective chart review of 62 patients between 2009 and 2017 with a diagnosis of SIgMD was performed for clinical and immunological features, and response to immunoglobulin therapy in symptomatic patients who also exhibited specific antibody deficiency. The majority of patients presented with recurrent and chronic upper and lower respiratory tract infections (73%), most often with recurrent sinusitis (29%), bronchitis (33%), pneumonia (21%), and recurrent urinary tract infections (16%). Forty three percent of patients had associated autoimmune diseases including Hashimoto's thyroiditis, and systemic lupus erythematosus. Approximately 35% of patients had atopic diseases, including allergic rhinitis and asthma. CD3+ T, CD4+ T, CD8+ T, and CD19+ B cells were normal in the majority of patients. IgG subclass deficiency was observed in approximately 22% of cases. Forty seven percent of patients exhibited specific anti-pneumococcal antibody deficiency. The six most common pneumococcal serotypes that were impaired in majority (>70%) of subjects included 3, 4, 9V, 9N, 12F, 23F. Eighteen (66%) of 27 patients with specific antibody deficiency received immunoglobulin therapy and almost all subjects responded to immunoglobulin therapy by decreased frequency of infections. No correlation was observed in immunological features, clinical manifestations, or response to therapy with serum IgM levels.","PeriodicalId":72163,"journal":{"name":"American journal of clinical and experimental immunology","volume":"8 6","pages":"55-67"},"PeriodicalIF":0.0,"publicationDate":"2019-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971419/pdf/ajcei0008-0055.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37569321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of fingolimod on white blood cell, lymphocyte and neutrophil counts in MS patients. 芬戈莫德对MS患者白细胞、淋巴细胞和中性粒细胞计数的影响。

American journal of clinical and experimental immunology Pub Date : 2019-04-15 eCollection Date: 2019-01-01

Aryan Rafiee Zadeh, Sara Parsa, Nooshin Tavoosi, Mohsen Farshi, Mohammad Farid Masaeli

{"title":"Effect of fingolimod on white blood cell, lymphocyte and neutrophil counts in MS patients.","authors":"Aryan Rafiee Zadeh, Sara Parsa, Nooshin Tavoosi, Mohsen Farshi, Mohammad Farid Masaeli","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Fingolimod is an immunomodulating oral treatment used for treating relapsing-remitting multiple sclerosis (RRMS). The exact mechanism for its action in preventing relapses is unknown. Also, its affect on immune cell populations remains unestablished.Objectives: This study will measure the changes in cell populations of WBCs, lymphocytes, and neutrophils in MS patients after one month of treatment.Methods: 66 MS patients from Isfahan Province with RRMS were chosen based on certain exclusion criteria and eligibility for fingolimod oral treatment. Initial cell counts for WBC, lymphocyte, and neutrophil cell populations were achieved. Fingolimod .5 mg daily treatment was then initiated under the supervision of a physician. After one month of treatment, cell counts were repeated. Statistical analysis was performed using SPSS.Results: Both lymphocyte and WBC mean cell counts were significantly decreased in this patient cohort. Neutrophil average cell counts were significantly increased in this 66 patient cohort. Only the decrease of WBC populations was significant for both male and female cohorts individually. Only female sub-cohorts were significantly changed for neutrophils and lymphocytes, increased and decreased respectively. Male sub-cohorts maintained the same directionality but failed to produce statistical significance.Conclusion: While fingolimod has been effectively proven as reducing lymphocyte cells in most patient populations, its effects on neutrophils have not been studied in abundance. Also, there may be sex-related differences in responses to fingolimod treatment with regards to lymphocytes and neutrophils, suggesting a possible difference in RRMS pathogenesis between males and females.","PeriodicalId":72163,"journal":{"name":"American journal of clinical and experimental immunology","volume":"8 2","pages":"9-15"},"PeriodicalIF":0.0,"publicationDate":"2019-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526352/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37275328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advances in the clinical and mechanism research of pollen induced seasonal allergic asthma. 花粉诱发季节性过敏性哮喘的临床和机理研究进展。

IF 1.4

American journal of clinical and experimental immunology Pub Date : 2019-02-15 eCollection Date: 2019-01-01

Zhi-Juan Xie, Kai Guan, Jia Yin

引用次数: 0

Serum levels of histamine and diamine oxidase in multiple sclerosis. 多发性硬化症患者血清组胺和二胺氧化酶水平。

American journal of clinical and experimental immunology Pub Date : 2018-12-20 eCollection Date: 2018-01-01

Aryan Rafiee Zadeh, Masih Falahatian, Fereshteh Alsahebfosoul

{"title":"Serum levels of histamine and diamine oxidase in multiple sclerosis.","authors":"Aryan Rafiee Zadeh, Masih Falahatian, Fereshteh Alsahebfosoul","doi":"","DOIUrl":"","url":null,"abstract":"Background: Multiple Sclerosis (MS) is an autoimmune disease of the central nervous system, mostly affecting young adults. Diamine oxidase is an enzyme essential for histamine production. Histamine which is produced mostly by mast cells can have effects on different aspects of immune system via its different histamine receptors (H1R, H2R, H3R and H4R). The crucial role of diamine oxidase and histamine in immune balance has been documented in different studies and experiments both on MS patients and on experimental allergic encephalomyelitis (EAE). In this regard, we aimed to measure the level of histamine and diamine oxidase in the serum of MS patients.Methods: A total number of 50 relapsing-remitting MS (RRMS) patients and 41 age and sex matched controls were enrolled in this study. Assessments of serum levels of histamine and diamine oxidase enzyme were performed using enzyme-linked immune sorbent assay (ELISA).Results: The serum levels of histamine and diamine oxidase in RRMS patients were lower than healthy controls (P-value = 0.00, for both).Conclusion: Our research team found significant low levels of histamine and diamine oxidase in RRMS patients; however the pathogenesis of this issue was unclear.","PeriodicalId":72163,"journal":{"name":"American journal of clinical and experimental immunology","volume":"7 6","pages":"100-105"},"PeriodicalIF":0.0,"publicationDate":"2018-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334194/pdf/ajcei0007-0100.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36911312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pressure pain assessment may predict the outcome of spinal cord stimulation for refractory epilepsy. 压痛评估可以预测脊髓刺激治疗难治性癫痫的结果。

American journal of clinical and experimental immunology Pub Date : 2018-12-20 eCollection Date: 2018-01-01

Li Feng, Li-Hua Fan, Duo-Zhi Wu

引用次数: 0

Treatment of multiple system atrophy - the past, present and future. 多系统萎缩的治疗——过去、现在和未来。

American journal of clinical and experimental immunology Pub Date : 2018-10-05

Haiyan Yu, Xiaoling Yuan, Lifeng Liu, Tian Wang, Dianrong Gong

引用次数: 0

Tumor-infiltrating regulatory T cells: origins and features. 肿瘤浸润调节性 T 细胞：起源与特征。

American journal of clinical and experimental immunology Pub Date : 2018-10-05 eCollection Date: 2018-01-01

Guoping Deng

引用次数: 0