Aesthetic surgery journal. Open forum最新文献

{"title":"Improving Striae Distensae With Combined Hyperdiluted Calcium Hydroxylapatite Injection and Fractional Microneedling Radiofrequency: A Pilot Study.","authors":"Haitham M Saleh, Daniella Fakih, Ahmed Elbeltagy, Sham AlZahabi, Hossam Elenany, Lorena Arrien, Nabil Fakih-Gomez","doi":"10.1093/asjof/ojag121","DOIUrl":"10.1093/asjof/ojag121","url":null,"abstract":"<p><p><i>Striae distensae</i> (SD), or stretch marks, are dermal scars resulting from disrupted collagen and elastin because of mechanical stress. Effective treatments, particularly for chronic striae alba, remain limited. Calcium hydroxylapatite (CaHA), a biostimulatory dermal filler, and fractional microneedling radiofrequency (RF) have individually demonstrated regenerative effects. This pilot study investigates the safety and efficacy of combining CaHA and fractional microneedling RF in improving SD. Eight female patients with abdominal SD (rubra or alba) underwent 1 session of hyperdiluted CaHA injection (1:4 dilution, 3 mL), followed by 3 monthly sessions of RF microneedling. Outcomes were evaluated 6 months after the final session using the Manchester Scar Scale (MSS), patient satisfaction scores, and adverse event monitoring. All participants (mean age 36.6 ± 7.3 years) completed the protocol. Mean MSS scores improved significantly from 14 ± 0.93 at baseline to 6.88 ± 1.64 posttreatment (<i>P</i> < .0001). The mean satisfaction score was 8.12 ± 1.72. Mild, transient erythema occurred in 2 cases; no serious adverse events were observed. This pilot study suggests that combining hyperdiluted CaHA with RF microneedling is a safe and effective approach for treating SD, yielding both clinical and patient-reported improvements. Larger controlled studies are warranted. Level of Evidence: 4 (Therapeutic) For image description, please refer to the figure legend and surrounding text.</p>","PeriodicalId":72118,"journal":{"name":"Aesthetic surgery journal. Open forum","volume":"8 ","pages":"ojag121"},"PeriodicalIF":1.9,"publicationDate":"2026-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13353822/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148426319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sequential Advancement Method: A Funnel-Based Technique for Safe Placement of Small Breast Implants.","authors":"Claire G Olivas, Orr Shauly, Daniel J Gould","doi":"10.1093/asjof/ojag142","DOIUrl":"10.1093/asjof/ojag142","url":null,"abstract":"<p><p>Recent aesthetic trends in breast augmentation favor smaller implants and minimal-incision techniques. However, placement of very small implants (100-165 cc) may pose unique mechanical challenges during funnel-assisted insertion because of the smaller contact surface area available for force distribution. The Sequential Advancement Method (SAM) provides a simple and reproducible solution by placing a larger sizer behind the implant within a sterile funnel-based implant delivery device to distribute force more evenly. This technique enables safe prepectoral placement through 2 cm incisions, reducing peak pressure and lowering tissue trauma. Although larger cohort studies are needed to validate outcomes, SAM offers a biomechanically sound strategy to support patient aesthetic preferences while decreasing the risk of implant-related complications. Level of Evidence: 5 (Therapeutic).</p>","PeriodicalId":72118,"journal":{"name":"Aesthetic surgery journal. Open forum","volume":"8 ","pages":"ojag142"},"PeriodicalIF":1.9,"publicationDate":"2026-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13457923/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148714746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of High-Intensity Facial Electrical Stimulation Technology on Elevation of the Midface: A Prospective Study With Ultrasound.","authors":"Steven Liew, Fadie Aziz, Nicky Lurie, Stefania Roberts","doi":"10.1093/asjof/ojag103","DOIUrl":"10.1093/asjof/ojag103","url":null,"abstract":"<p><p>Nonsurgical skin tightening and lifting devices have gained significant popularity because of their ability to provide facial rejuvenation without the downtime and risks associated with surgery. Technologies utilizing high-intensity facial electrical stimulation (HIFES) in combination with synchronous radiofrequency (RF) have shown promise in achieving lifting effects in the upper and midface. The aim of this study was to evaluate the effectiveness of combined HIFES and synchronous RF treatment of the midface in producing lifting of the modiolus relative to 2 fixed anatomical landmarks: the superior tragal point (STP) and lateral canthal point (LCP). A prospective single-arm cohort study was conducted with 8 participants completing 4 weekly HIFES and synchronous RF treatments. The position of the modiolus was measured at 3 time points: pretreatment, immediately after the first treatment, and 3 months after the final session. The modiolus was localized with ultrasound, and distances to the STP and LCP were recorded. Means were compared using repeated-measure analysis of variance with pairwise <i>t</i>-tests; the Wilcoxon signed-rank test was performed as a robustness check. The modiolus demonstrated statically significant elevation in an oblique cephaloposterior vector toward the tragus. Modiolus-STP distance decreased from baseline to 3 months posttreatment (right: 0.56 cm, <i>P</i> < .01; left: 0.31 cm, <i>P</i> = .04). Modiolus-LCP distance also decreased (right: 0.28 cm, <i>P</i> = .06; left: 0.14 cm, <i>P</i> = .45), although not statistically significant. In this preliminary study, HIFES and synchronous RF treatment produced significant measurable lifting of the modiolus consistent with the anatomical pull of the zygomaticus complex. Larger studies with longer follow-up are warranted to further characterize these effects. <b>Level of Evidence</b>: 4 (Therapeutic) For image description, please refer to the figure legend and surrounding text.</p>","PeriodicalId":72118,"journal":{"name":"Aesthetic surgery journal. Open forum","volume":"8 ","pages":"ojag103"},"PeriodicalIF":1.9,"publicationDate":"2026-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13367438/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148450729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Effects and Safety of Radiofrequency Microneedling for the Management of Melasma: A Retrospective Study.","authors":"Han-Bi Kim, So-Yeon Lee, Ji-Young Um, Song-Yi Baek, Hye-One Kim, Narendra Kumar","doi":"10.1093/asjof/ojag143","DOIUrl":"10.1093/asjof/ojag143","url":null,"abstract":"<p><strong>Background: </strong>Melasma is a chronic hyperpigmentary disorder that is difficult to treat in patients with Fitzpatrick phototypes III to VI because of the risk of postinflammatory hyperpigmentation. Radiofrequency microneedling (RFMN) is an emerging modality that targets dermal photoaging while minimizing epidermal injury.</p><p><strong>Objectives: </strong>The aim of this study was to evaluate the clinical effectiveness and safety of POTENZA RFMN in patients with melasma in a real-world retrospective cohort.</p><p><strong>Methods: </strong>The authors conducted a retrospective pre-post observational study of adults with clinically diagnosed melasma treated with POTENZA (Jeisys Medical Inc., Seoul, Republic of Korea) at a tertiary dermatology center in Seoul, Republic of Korea, between May 2022 and May 2025. All treatments were delivered in bipolar mode at 1 MHz with an insulated microneedle tip (I-25 or I-49). The primary outcome was the change in modified Melasma Area and Severity Index (mMASI) from baseline to posttreatment. Secondary outcomes included physician-rated improvement, patient satisfaction, changes in texture and brightness, and adverse events. Sensitivity analyses were performed to assess the robustness of the findings after excluding patients who received concurrent topical depigmenting agents.</p><p><strong>Results: </strong>Fifty patients (mean age 40.7 years; 60% female; Fitzpatrick type III in 80%) were included. Median (interquartile range) mMASI decreased from 6.15 (4.90-8.62) to 3.75 (2.18-5.92) (median ΔmMASI -1.80; median percentage reduction 32.3%; <i>P</i> < .001). A responder analysis using a ≥30% mMASI reduction threshold identified 27/50 patients (54%) as responders. No significant differences in ΔmMASI were observed by melasma pattern or Fitzpatrick phototype; however, male patients showed greater median improvement than female patients (-2.70 vs -1.65; <i>P</i> = .039). In the sunscreen-only subgroup (<i>n</i> = 31, functional monotherapy), the median percentage mMASI reduction was 42.3%, consistent with the overall cohort. Independent reviewers rated clinical improvement in 98% of patients (36% marked, 36% moderate, and 26% slight), and 90% of patients reported satisfaction. Procedure-related adverse events occurred in 12% of cases; all were mild, transient, and resolved without intervention.</p><p><strong>Conclusions: </strong>POTENZA RFMN produced clinically meaningful mMASI reductions, high physician-rated improvement, high patient satisfaction, and a favorable safety profile in this predominantly Fitzpatrick type III cohort of patients with mild-to-moderate melasma. These findings support RFMN as a promising adjunctive option and warrant confirmation in prospective controlled trials.</p><p><strong>Level of evidence 4 risk: </strong>For image description, please refer to the figure legend and surrounding text.</p>","PeriodicalId":72118,"journal":{"name":"Aesthetic surgery journal. Open forum","volume":"8 ","pages":"ojag143"},"PeriodicalIF":1.9,"publicationDate":"2026-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13457909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148714708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Systematic Review and Meta-Analysis of the Role of Open Platysmaplasty in Facelift and Necklift Surgery: Comparative Outcomes of Closed- vs Open-Neck Rejuvenation With Liposuction Using FACE-Q Scales.","authors":"Giuseppe Fiore, Naghmeh Naderi, Benedict Reed, Lauren Andrea Laird, Rana Das-Gupta","doi":"10.1093/asjof/ojag140","DOIUrl":"10.1093/asjof/ojag140","url":null,"abstract":"<p><p>Facial and neck rejuvenation techniques have evolved significantly, aiming to achieve optimal patient satisfaction with minimal invasiveness. Open platysmaplasty techniques allow direct access to anatomical structures but involve additional scarring, whereas closed techniques are less invasive but might provide limited correction. There remains uncertainty regarding patient-reported outcomes between these approaches. This systematic review and meta-analysis assessed patient-reported outcomes (FACE-Q Aesthetic Module scores) comparing open- vs closed-neck rejuvenation techniques, with and without liposuction. A systematic review was performed following Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 guidelines, searching databases (MEDLINE [Ovid], Embase [Ovid], PubMed, and Cochrane Library) from inception to November 2024. Studies comparing open- and closed-necklift techniques and reporting FACE-Q scores were included. Data were analyzed using weighted means, pooled standard deviations, and Welch's <i>t</i>-tests to compare satisfaction scores. Nine studies with 847 patients were analyzed. When liposuction was employed, open techniques significantly improved neck aesthetic satisfaction (mean FACE-Q = 81.5) compared with closed techniques (mean FACE-Q = 77.5, <i>P</i> = .022), although chin scores were comparable (<i>P</i> = .268). Closed techniques without liposuction yielded the highest satisfaction scores for both chin (mean FACE-Q = 86.4) and neck (mean FACE-Q = 86.6), significantly exceeding open techniques with liposuction (<i>P</i> < .01). Closed-neck rejuvenation techniques without liposuction showed the highest patient-reported outcomes for appropriately selected patients, emphasizing the importance of individualized surgical planning. Open techniques retain significant value for patients requiring more extensive anatomical correction. Level of Evidence: 4 (Therapeutic).</p>","PeriodicalId":72118,"journal":{"name":"Aesthetic surgery journal. Open forum","volume":"8 ","pages":"ojag140"},"PeriodicalIF":1.9,"publicationDate":"2026-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13398994/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148586065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of Board-Certified Plastic Surgeons Using Artificial Intelligence: An Accuracy Assessment.","authors":"Rohun Gupta, Atharva M Bhagwat, Mei Hainline, Herluf Lund, Brian A Mailey, Sumesh Kaswan","doi":"10.1093/asjof/ojag123","DOIUrl":"10.1093/asjof/ojag123","url":null,"abstract":"<p><strong>Background: </strong>Artificial intelligence (AI), particularly large language models like ChatGPT (OpenAI, San Francisco, CA) and Gemini (Google, Mountain View, CA), is increasingly used in healthcare for diagnosis, education, and research. Because interest in cosmetic procedures rises, patients face growing difficulty in selecting qualified providers because of unclear credentials and expanding practitioner types.</p><p><strong>Objectives: </strong>This study evaluates whether AI can help patients accurately identify board-certified plastic surgeons, addressing a current gap in the literature.</p><p><strong>Methods: </strong>Four leading AI tools-ChatGPT, Perplexity (Perplexity AI, San Francisco, CA), Gemini, and Claude (Anthropic, San Francisco, CA)-were evaluated by asking each to name board-certified plastic surgeons across all 50 US states. Results were verified through independent internet searches and the American Board of Plastic Surgery to confirm certification status. Statistical analysis using GraphPad Prism (Boston, MA) found differences between tools, with significance set at <i>α</i> = .05.</p><p><strong>Results: </strong>Across 1000 results, overall accuracy in identifying plastic surgeons was 94.1%, with Gemini performing best, followed by Perplexity, ChatGPT, and Claude, with statistically significant differences. Most nonplastic surgeons were otolaryngologists and general surgeons, with no difference between AI models in error type distribution. Gemini scored the highest in regards to board certification accuracy, showing significant differences compared with the other models.</p><p><strong>Conclusions: </strong>Because the field of aesthetic procedures grows and more providers enter the market, patients must be able to make well-informed choices when selecting a practitioner. Although AI offers a promising tool for identifying board-certified plastic surgeons, its potential for error means patients should independently verify the information.</p><p><strong>Level of evidence 5 therapeutic: </strong></p>","PeriodicalId":72118,"journal":{"name":"Aesthetic surgery journal. Open forum","volume":"8 ","pages":"ojag123"},"PeriodicalIF":1.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13331345/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148392576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk of Recall Among Plastic Surgery Devices Cleared Through the FDA 510(k) Pathway.","authors":"Ravi Dhawan, Alexandra Boric, Orr Shauly, Troy Marxen, Anjali Om, Kendall Brooks, Gabriela García Nores, Albert Losken","doi":"10.1093/asjof/ojag126","DOIUrl":"10.1093/asjof/ojag126","url":null,"abstract":"<p><strong>Background: </strong>The FDA 510(k) pathway is the predominant route by which medical devices reach the US market. Previous studies have examined recall risk across broad FDA panels, but none have characterized plastic surgery devices or compared recall patterns across subcategories within the field.</p><p><strong>Objectives: </strong>The aim of this study was to determine the rate and severity of FDA recalls among 510(k)-cleared plastic surgery devices, compare recall risk across subcategories, and benchmark against all other 510(k) devices.</p><p><strong>Methods: </strong>All 510(k)-cleared devices (2008-2023) were obtained from the FDA premarket notification database. Two reviewers classified 234 surgery panel product codes, identifying 103 plastic surgery codes (3194 devices) in 8 subcategories. Each device was matched to the FDA recall database by its 510(k) number. All remaining 510(k) devices (<i>n</i> = 45,182) served as comparator. Recall rates were compared using χ² tests and risk ratios (RR); time to first recall was modeled with Cox proportional hazards regression with Bonferroni correction.</p><p><strong>Results: </strong>Of 3194 plastic surgery devices, 197 (6.2%) were recalled, including 11 Class I recalls (0.3%). The recall rate for all other 510(k) devices was 11.4% (RR, 0.54; 95% CI, 0.47-0.62; <i>P</i> < .001). After Bonferroni correction, 4 subcategories had elevated recall hazard vs lasers and energy: implants and fixation (hazard ratio [HR], 3.64), negative pressure wound therapy (HR, 2.53), surgical mesh and acellular dermal matrices (HR, 2.46), and wound closure (HR, 2.01).</p><p><strong>Conclusions: </strong>Plastic surgery 510(k) devices had a lower recall rate than nonplastic surgery devices, although risk varied substantially across subcategories. These data provide a specialty-specific baseline for postmarket device surveillance.</p><p><strong>Level of evidence 5 therapeutic: </strong>For image description, please refer to the figure legend and surrounding text.</p>","PeriodicalId":72118,"journal":{"name":"Aesthetic surgery journal. Open forum","volume":"8 ","pages":"ojag126"},"PeriodicalIF":1.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13344102/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148414016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three-Dimensional Morphometric Trajectories Following Lip Lift With or Without Fat Grafting in Facial Feminization Patients.","authors":"Victoria Kong, Andrew Salib, Martin Kauke-Navarro, Emily Parker, Jake Moscarelli, Omar Allam, Samira Glaeser-Khan, Samuel Knoedler, Michael Alperovich","doi":"10.1093/asjof/ojag135","DOIUrl":"10.1093/asjof/ojag135","url":null,"abstract":"<p><strong>Background: </strong>Subnasal lip lifts address perioral aging, but long-term quantitative data on postoperative changes and permanence remain limited.</p><p><strong>Objectives: </strong>The aim of this study was to provide the first 3-dimensional (3D) evaluation of morphometric changes after subnasal lip lift ± autologous fat grafting over time.</p><p><strong>Methods: </strong>A retrospective cohort (2022-2025) of facial feminization patients undergoing subnasal lip lift ± fat grafting was analyzed. Standardized VECTRA 3D imaging measured philtral height, vermilion height and width, nasal base width, columella-labial angle, surface area, and lip volume preoperatively and at serial postoperative intervals. Early changes (3 months) were compared using <i>t</i> tests and longitudinal trajectories with linear mixed-effects models.</p><p><strong>Results: </strong>Forty patients were included (lip lift alone, <i>n</i> = 10; lip lift + fat grafting, <i>n</i> = 30). Both cohorts showed significant early philtral shortening (-2.92 ± 1.53 mm, <i>P</i> = .013 vs -5.95 ± 1.77 mm, <i>P</i> < .001) and increased upper vermilion surface area (1.40 ± 0.86 cm², <i>P</i> = .022 vs 1.42 ± 1.23 cm², <i>P</i> = .022). Fat grafting produced greater early volumetric augmentation (1.18 ± 0.86 vs 0.53 ± 0.25 cc), although between-group differences did not reach statistical significance. Mixed-effects modeling showed significant divergence in permanence. Philtral shortening showed 43% retention by 24 months (<i>P</i> = .003), whereas volumetric and surface area gains approached zero by 22 and 24 months, respectively.</p><p><strong>Conclusions: </strong>There is measurable philtral shortening after subnasal lip lift. However, partial relengthening occurs over time. Additionally, early gains in vermilion display and lip volume decrease substantially by 2 years. Fat grafting enhances early augmentation but shows limited long-term retention.</p><p><strong>Level of evidence 3 therapeutic: </strong></p>","PeriodicalId":72118,"journal":{"name":"Aesthetic surgery journal. Open forum","volume":"8 ","pages":"ojag135"},"PeriodicalIF":1.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13361976/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148439173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Redefining Neck Rejuvenation: The Novel Hyoid-to-Mastoid Crevasse Neo-Ligament and OnderKaak Angle in Deep Plane Neck Lift.","authors":"","doi":"10.1093/asjof/ojag115","DOIUrl":"10.1093/asjof/ojag115","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1093/asjof/ojag009.].</p>","PeriodicalId":72118,"journal":{"name":"Aesthetic surgery journal. Open forum","volume":"8 ","pages":"ojag115"},"PeriodicalIF":1.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13322384/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148370985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uniform Treatment Protocol With Hybrid Stromal Vascular Fraction and Platelet-Rich Plasma on Micro-Fat Grafting With Facelifting: A Preliminary Retrospective 3D Vectra Observational Study.","authors":"Gordon Sasaki","doi":"10.1093/asjof/ojag133","DOIUrl":"10.1093/asjof/ojag133","url":null,"abstract":"<p><p>Hybrid stromal vascular fraction (SVF), a combination of mechanical SVF (M-SVF) and stromal vascular matrix (M-SVM) fraction, is an alternative method to overcome limitations of low cell counts by conventional mechanical and enzymatic methods. The aim of this report was to observe the volume retention in facial fat grafts enhanced with hybrid M-SVF and platelets in pure platelet-rich plasma (P-PRP). Using a 5:1 v/v ratio, proportional volumes of micro-fat to proportional volumes and quantitative cell counts of M-SVF/M-SVM and PRP were delivered to palpebral-malar groove/malar fat pad units and evaluated by Vectra Analysis for volumetric changes over 12 months. Collective analysis of 9 female patients (average age: 65.6 years) revealed the percentage volume retention increased from baseline to 3 months (54.9%), then progressively declined to its nadir at 5 to 7 months (38.4%), then rebounded to peak percentage values at 10 to 12 months (69.5%), <i>P</i> > .05. Investigators' ratings on the Investigator Global Assessment Improvement Scale scores are assessed. There were no reported long-term side effects or complications. The application of M-SVF/M-SVM and platelets supported micro-fat grafting with simultaneous facelifting (necklifting) in a safe manner for patients older than 55 years of age in this preliminary study. However, the hypothesis-generated associations of SVF/SVM and platelets to improve volumetric fat changes were observational only, so that conclusions of a causal relationship could not be established in this limited uncontrolled trial. Thus, interpretation of results should be viewed with caution until future randomized controlled trials are completed. <b>Level of Evidence: 4 (Therapeutic)</b> For image description, please refer to the figure legend and surrounding text.</p>","PeriodicalId":72118,"journal":{"name":"Aesthetic surgery journal. Open forum","volume":"8 ","pages":"ojag133"},"PeriodicalIF":1.9,"publicationDate":"2026-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13457925/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148714756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}