Advanced research in gastroenterology & hepatology最新文献_第8页

Migration: Epidemic of Mental Disorders Caused by Global Warming and Inequality 移民:全球变暖和不平等导致的精神疾病流行

Advanced research in gastroenterology & hepatology Pub Date : 2019-01-22 DOI: 10.19080/argh.2019.12.555831

R. Skopec

{"title":"Migration: Epidemic of Mental Disorders Caused by Global Warming and Inequality","authors":"R. Skopec","doi":"10.19080/argh.2019.12.555831","DOIUrl":"https://doi.org/10.19080/argh.2019.12.555831","url":null,"abstract":"Rising global temperatures may be driving up rates of mental illness as well, a new study suggests. Last year was the third hottest on record, and 2016 was the hottest ever. And more people are struggling with mental health issues in the US now than any other time in the nation’s history. Superior predatory skills led to the evolutionary triumph of jawed vertebrates. However, the mechanisms by which the vertebrate brain controls predation remain largely unknown. Here, we reveal a critical role for the central nucleus of the amygdala in predatory hunting. Both optogenetic and chemogenetic stimulation of central amygdala of mice elicited predatory-like attacks upon both insect and artificial prey. Coordinated control of cervical and mandibular musculatures, which is necessary for accurately positioning lethal bites on prey, was mediated by a central amygdala projection to the reticular formation in the brainstem. populations during active hunting, we performed electromyogram monitoring of the masseter muscle concomitantly to array neuronal recordings. Principal component analyses of the neuronal data revealed that ∼40% of the recorded neurons increased activity during insect hunting, with hunting-excited CeA neurons maintaining activity levels throughout prey pursuit. The Central Nucleus of the Amygdala Controls Cervical-Mandibular Systems by Acting on Inhibitory Interneurons of the Parvocellular Reticular Formation. The Parvocellular Reticular Formation Contains Both Mandibular and Cervical Premotor Neurons. We investigated in greater depth the reticular circuitry mediating CeA control over craniofacial musculatures.","PeriodicalId":72074,"journal":{"name":"Advanced research in gastroenterology & hepatology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68370852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Noninvasive Evaluations of Non-alcoholic Fatty Liver Disease in Pediatric Populations 非酒精性脂肪肝在儿科人群中的无创评估

Advanced research in gastroenterology & hepatology Pub Date : 2019-01-17 DOI: 10.19080/ARGH.2019.12.555829

K. Reyes

引用次数: 0

Pathology of Cardiovascular System in Patients with Inflammatory Bowel Diseases 炎症性肠病患者心血管系统的病理学

Advanced research in gastroenterology & hepatology Pub Date : 2019-01-17 DOI: 10.19080/argh.2019.12.555830

Khlynova Ov

{"title":"Pathology of Cardiovascular System in Patients with Inflammatory Bowel Diseases","authors":"Khlynova Ov","doi":"10.19080/argh.2019.12.555830","DOIUrl":"https://doi.org/10.19080/argh.2019.12.555830","url":null,"abstract":"The purpose the work was studying of cardiovascular system disease prevalence and structure in persons with the inflammatory bowel diseases (IBD) using Gastroenterology department of the Perm regional hospital as an example. It was the retrospective one-stage research including studying case histories of the patients with ulcerative colitis (UC) and Crohn’s disease (CD) examined and treated in gastroenterological clinic for the period of 2013-2016. There were 291 patients with IBD, chronic cardiovascular pathology was revealed only in 90 patients. Comparative analysis showed that combined diseases were mainly spread in men with UC of middle and advanced age. The most typical for them was combination of UC and ischemic heart disease (50% of cases). Cardiovascular system pathology was 1.5 times more common for women with CD pathology. Besides CD, thromboses of peripheral veins (45% of cases) and myocardial dystrophy (24.5% of cases) were the most frequent pathologies. Due to the small number of patients with IBD and cardiovascular system pathology, it is not possible to claim unambiguously the degree of cardiac disorders in patients with IBD. Thus, it is planned to increase the number of observations to reach statistically optimum conclusion. Studying of this problem is of special practical importance for the possibility to regard patients with IBD as a group of patients with high cardiovascular risk. This will necessitate a number of preventive actions to prevent cardiovascular accidents of fatal and non-fatal","PeriodicalId":72074,"journal":{"name":"Advanced research in gastroenterology & hepatology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49400397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Why Young Patients are Having Colorectal Cancer? 为什么年轻患者会患结直肠癌?

Advanced research in gastroenterology & hepatology Pub Date : 2019-01-16 DOI: 10.19080/argh.2019.12.555828

E. R. García

引用次数: 0

A Summary of the Main Biomarkers for Diagnosis and Prognosis of Sporadic Colorectal Cancer: A Review 散发性癌症诊断和预后的主要生物标志物综述

Advanced research in gastroenterology & hepatology Pub Date : 2019-01-11 DOI: 10.19080/argh.2019.11.555825

E. M. Goloni-Bertollo

{"title":"A Summary of the Main Biomarkers for Diagnosis and Prognosis of Sporadic Colorectal Cancer: A Review","authors":"E. M. Goloni-Bertollo","doi":"10.19080/argh.2019.11.555825","DOIUrl":"https://doi.org/10.19080/argh.2019.11.555825","url":null,"abstract":"Sporadic colorectal cancer (SCRC) affects regions of the large intestine (colon) and rectum that are not of family origin. The carcinogenesis process involves the interaction between environmental and genetic factors. This tumor is characterized by intestinal obstruction, bleeding (hematochezia, enterorrhagia), an altered bowel habit, and systemic conditions, such as weight loss. Some risk factors for SCRC are age over 60 years, a diet with high saturated fat, red meat, alcohol consumption, and smoking. An early diagnosis is essential for effective patient treatment and survival. Finding more effective and less invasive tumor, such as biomarkers, are important for ensuring that people participate in cancer screenings. Some studies have evaluated molecular biomarkers, such as micro ribonucleic acids (microRNAs, or miRNAs) and genes, in relation to the pathways leading to SCRC carcinogenesis, and it has been found that many of these biomarkers are highly expressed in this type of tumor. This review shows data from the literature search in PubMed in the period from January 2017 to April 2018 focusing news biomarkers in SCRC, including microsatellite instability, genes, and micro ribonucleic acids (micro RNAs, or miRNAs), associated with diagnosis, prognosis, and treatment in blood, tissue and feces samples. Thus, this literature review shows that microsatellite instability and gene markers have been extensively studied and characterized as biomarkers in the diagnosis, prognosis, and treatment of SCRC. In addition, some miRNAs have been demonstrated as good noninvasive biomarkers in stool and plasma samples.","PeriodicalId":72074,"journal":{"name":"Advanced research in gastroenterology & hepatology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41360720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Perforated Stomach Ulcer on the Background of Her Bleeding 出血背景下的胃溃疡穿孔

Advanced research in gastroenterology & hepatology Pub Date : 2019-01-11 DOI: 10.19080/ARGH.2019.11.555824

Shaposhnikov Veniamin Ivanovich

引用次数: 0

Study the Effect of Weight Loss in Improvement of Hepatic Fibrosis in Patients with Chronic HCV 减肥对慢性丙型肝炎患者肝纤维化改善作用的研究

Advanced research in gastroenterology & hepatology Pub Date : 2019-01-11 DOI: 10.19080/argh.2019.12.555826

Khaled Metwally

{"title":"Study the Effect of Weight Loss in Improvement of Hepatic Fibrosis in Patients with Chronic HCV","authors":"Khaled Metwally","doi":"10.19080/argh.2019.12.555826","DOIUrl":"https://doi.org/10.19080/argh.2019.12.555826","url":null,"abstract":"Background: Liver fibrosis considered as a reversible disease, but curing the primary hepatic disease, sometimes, doesn’t mean fibrosis improvement. Steatosis could be one of the reasons responsible for this failure. Weight loss has been shown to improve fibrosis, but few data is available from Egypt. Objective: to test the effect of weight reduction on the degree of fibrosis improvement in patients with chronic hepatitis C (CHC). Methods: Adult patients (> 18 years) were recruited from hepatitis Cout patient’s clinic, National Liver Institute (NLI), University of Menoufyia, from 2016 to 2018. Results: Thirty CHC patients with moderate and severe steatosis, who were initially assessed by liver biopsy and Transient elastography (TE) for their fibrosis stage, were followed up by Transient elastography after losing >10% of their weight. Median age was 44.7 years (29 – 59 years) and 50% were men. The degree of fibrosis and its values improved with the significant weight loss (p < 0.01 for both). Conclusion: Weight reduction is associated with improvement of hepatic fibrosis in patient with CHC. Elastography; NAFLD: Nonalcoholic Fatty Liver Disease; N: Number, SD: Standard Deviation, BMI: Body Mass Index; ALT: Alanine Aminotransferase, AST: Aspartate Aminotransferase, RNA: Ribonucleic Acid, INR: International Normalized Ratio, kPa: Kilopascal","PeriodicalId":72074,"journal":{"name":"Advanced research in gastroenterology & hepatology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45439355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cannula, Conduit, Subway: Syringoma 套管，导管，地铁:注射器瘤

Advanced research in gastroenterology & hepatology Pub Date : 2019-01-01 DOI: 10.19080/argh.2019.13.555865

A. Bajaji

引用次数: 0

Opposing Roles of BMP and TGF-β Signaling Pathways in Pancreatitis: Mechanisms and Therapeutic Implication. BMP和TGF-β信号通路在胰腺炎中的对立作用:机制和治疗意义。

Advanced research in gastroenterology & hepatology Pub Date : 2019-01-01 Epub Date: 2019-09-04

Yanna Cao, Madeline Drake, Joy Davis, Baibing Yang, Tien C Ko

引用次数: 0

Hepatitis B Elimination - Preventing Vertical Transmission is must 消除乙型肝炎-防止垂直传播是必须的

Advanced research in gastroenterology & hepatology Pub Date : 2019-01-01 DOI: 10.19080/argh.2019.13.555857

V. Malhotra

引用次数: 0