{"title":"消除乙型肝炎-防止垂直传播是必须的","authors":"V. Malhotra","doi":"10.19080/argh.2019.13.555857","DOIUrl":null,"url":null,"abstract":"The proportion of babies that became HBV chronic carriers is about 10% to 30% for mothers who are HBsAg positive but HBeAg negative. However, the incidence of perinatal infections is higher, i.e. 70% to 90%, when the mother is also HBeAg positive [3]. There are three possible routes of transmission of HBV from infected mothers to infants: transplacental transmission of HBV in utero, natal transmission during delivery or post-natal transmission during care of infant or through breast milk [4]. Though several studies on epidemiology of viral hepatitis in pregnancy are available, there is paucity of data on maternal to child transmission (MTCT) of HBV during pregnancy.","PeriodicalId":72074,"journal":{"name":"Advanced research in gastroenterology & hepatology","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Hepatitis B Elimination - Preventing Vertical Transmission is must\",\"authors\":\"V. Malhotra\",\"doi\":\"10.19080/argh.2019.13.555857\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The proportion of babies that became HBV chronic carriers is about 10% to 30% for mothers who are HBsAg positive but HBeAg negative. However, the incidence of perinatal infections is higher, i.e. 70% to 90%, when the mother is also HBeAg positive [3]. There are three possible routes of transmission of HBV from infected mothers to infants: transplacental transmission of HBV in utero, natal transmission during delivery or post-natal transmission during care of infant or through breast milk [4]. Though several studies on epidemiology of viral hepatitis in pregnancy are available, there is paucity of data on maternal to child transmission (MTCT) of HBV during pregnancy.\",\"PeriodicalId\":72074,\"journal\":{\"name\":\"Advanced research in gastroenterology & hepatology\",\"volume\":\"1 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advanced research in gastroenterology & hepatology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.19080/argh.2019.13.555857\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced research in gastroenterology & hepatology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.19080/argh.2019.13.555857","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Hepatitis B Elimination - Preventing Vertical Transmission is must
The proportion of babies that became HBV chronic carriers is about 10% to 30% for mothers who are HBsAg positive but HBeAg negative. However, the incidence of perinatal infections is higher, i.e. 70% to 90%, when the mother is also HBeAg positive [3]. There are three possible routes of transmission of HBV from infected mothers to infants: transplacental transmission of HBV in utero, natal transmission during delivery or post-natal transmission during care of infant or through breast milk [4]. Though several studies on epidemiology of viral hepatitis in pregnancy are available, there is paucity of data on maternal to child transmission (MTCT) of HBV during pregnancy.
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