Accounts of materials research最新文献

{"title":"Bridging Direct Air Capture and CO2 Conversion through Redox-Active Systems","authors":"Abhijit Hazra, Maryam Abdinejad","doi":"10.1021/accountsmr.6c00075","DOIUrl":"https://doi.org/10.1021/accountsmr.6c00075","url":null,"abstract":"Figure 1. <b>Evolution of electrochemical carbon capture toward electrochemical direct air capture (e-DAC).</b> Early electrochemical CO<sub>2</sub> separation concepts developed from pH-swing and life-support systems into broader ECC strategies, including redox-mediated capture and electro-swing adsorption. Recent advances in molecular design, electrolyte control, and reactor engineering have begun to extend these approaches to atmospheric CO<sub>2</sub> capture, defining the emergence of e-DAC. Figure 2. <b>Redox-active molecular capture and electrochemical reactor configurations for integrated CO<sub>2</sub> capture and conversion.</b> (Top) Representative redox-active molecular carriers capable of reversible CO<sub>2</sub> binding through electrochemical reduction–oxidation cycles. Molecular design strategies enable tuning of reduction potentials, CO<sub>2</sub> binding affinity, and chemical stability. (Bottom left) H-cell configuration used for mechanistic studies of electrochemical CO<sub>2</sub> capture. (Bottom center) Flow-cell system enabling continuous operation through spatial separation of reduction and oxidation processes. (Bottom right) Schematic of integrated CO<sub>2</sub> direct air capture and utilization, illustrating coupling of capture with downstream electrochemical conversion processes. Reproduced from ref (16). Copyright 2026 the authors of ref (16), under exclusive license to Springer Nature. <b>Abhijit Hazra</b> obtained his Ph.D. from the Academy of Scientific and Innovative Research, based on his research at CSIR-Central Mechanical Engineering Research Institute, where he developed metal–organic frameworks for sensing and electrocatalytic applications. He subsequently carried out postdoctoral research with at CSIR-Indian Institute of Chemical Technology, focusing on porous organic polymers and related materials for CO<sub>2</sub> capture, gas separation, and catalytic transformations. He is currently a postdoctoral researcher with Professor Maryam Abdinejad at Technical University of Denmark (DTU). His current work aligns closely with the integration of e-DAC and CO<sub>2</sub> reduction reaction technologies, where he contributes to the development of functional materials capable of capturing low-concentration CO<sub>2</sub> and enabling its electrochemical conversion into value-added products. His research emphasizes the development of redox-active and structurally tunable systems for efficient and scalable carbon capture and utilization strategies. <b>Maryam Abdinejad</b> is an assistant professor in the Department of Energy Conversion and Storage at DTU. She received her Bachelor’s degree in Applied Chemistry and holds M.Sc. degrees in Molecular Science and Renewable Energy from the United Kingdom and Canada, respectively. She obtained her Ph.D. from the University of Toronto, where she focused on the design of molecular and hybrid systems for electrochemical CO<sub>2</sub> conversion to value-added products. She","PeriodicalId":72040,"journal":{"name":"Accounts of materials research","volume":"147 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147736013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interface-Confined Metal Oxide Nanolayers: From Metal Substrate to Oxide Substrate","authors":"Rongtan Li, Jinhu Dong, Qiang Fu, Xinhe Bao","doi":"10.1021/accountsmr.6c00009","DOIUrl":"https://doi.org/10.1021/accountsmr.6c00009","url":null,"abstract":"The evolution of metal oxides, a cornerstone class in heterogeneous catalysis, has progressed from bulk materials to low-dimensional structures designed to maximize active site exposure. Among them, two-dimensional (2D) metal oxide nanolayers supported on metal or oxide surfaces are particularly distinctive, as their unique geometric and electronic structures endow them with enhanced activity and controllable selectivity in catalytic reactions. Their properties are further shaped by the interface with the substrate, which can induce unusual structural characteristics such as non-stoichiometry, metastable state, structural flexibility, and charge redistribution. While extensive research has elucidated the role of the oxide–metal interface in modulating catalytic behavior, the mechanistic understanding of the oxide–oxide interface still lags far behind that of the oxide–metal interface.","PeriodicalId":72040,"journal":{"name":"Accounts of materials research","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147732316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Particle–Nanofiber Superstructures","authors":"Bin Zhao, Luiz G. Greca, Bruno D. Mattos","doi":"10.1021/accountsmr.5c00308","DOIUrl":"https://doi.org/10.1021/accountsmr.5c00308","url":null,"abstract":"Superstructured particle assemblies are sought as efficient platforms for transferring properties from the nano- to macroscale while combining modularity and versatility with facile and scalable fabrication processes. Such assemblies are achieved by structuring primary particle using various assembly techniques, which enables the control and customization of morphological features across length scales. Ensuring high cohesion within these assemblies is crucial for practical applications, both to mitigate nanotoxicity and bioaccumulation and to prevent the loss of performance resulting from subunit detachment. In this Account, the integration of biobased nanofibers into particle constructs is discussed in terms of their ability to act as universal binders that offer several advantages over case-specific strategies to develop strength in superstructures. Cellulose nanofibers, among others, have a remarkable capacity to confer cohesion to virtually any particulate system, thereby improving strength and toughness and opening several opportunities to manipulate their nano- to macrostructures. At the nano- and microscale, nanofibers can disrupt particle lattices, thereby enhancing access to surface functionalities. At the macroscale, nanofibers enable control over the viscoelastic properties of particle suspensions and govern their consolidation into dried particle–nanofiber constructs. Cellulose nanofibers are the most widely used in supraparticle fabrication, but several other fibrillar nanomaterials from chitin, amyloid, and aramid show promise for a broad range of particle–nanofiber assemblies. This Account presents a detailed review of the ability of nanofibers to enhance cohesion and manipulate supraparticle structures. First, cellulose nanofibers are introduced, and aspects like extraction, surface chemistry, modification, and colloidal properties are discussed, as they play important roles in transferring cohesion from the nanofibrillar network onto the particle–nanofiber assembly. Then, nanofiber–particle interactions in dilute and concentrated regimes are discussed and related to the forces and phenomena that drive the consolidation of these robust constructs. Analyses of mesh size and crowding of associated nanofiber networks are put into perspective and discussed in terms of particle entrapment and particle–nanofiber interactions prior to consolidation. Methods currently employed to fabricate superstructured materials are presented, including casting on superhydrophobic surfaces, templates and hydrophilic substrates, foaming for particle–nanofiber networks at air–liquid interfaces, 3D printing, and spray drying. Finally, practical applications for particle–nanofiber superstructures are introduced and discussed in terms of the gains obtained by using well-defined nanostructured materials and supraparticles.","PeriodicalId":72040,"journal":{"name":"Accounts of materials research","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147726570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functionalized Organic/Polymeric Materials for Perovskite and Organic Solar Cells","authors":"Haiyang Chen, Yege Jing, Juan Zhu, Yaowen Li","doi":"10.1021/accountsmr.5c00344","DOIUrl":"https://doi.org/10.1021/accountsmr.5c00344","url":null,"abstract":"Perovskite solar cells (pero-SCs) and organic solar cells (OSCs), owing to their solution processability, lightweight form factors, and exceptional mechanical flexibility, have emerged as leading contenders to complement silicon photovoltaics in distributed energy systems. In recent years, rapid progress has pushed the power conversion efficiencies of rigid laboratory-scale pero-SCs beyond 27% and OSCs above 21%. Yet, translating these achievements into practical deployment requires simultaneous advances in flexibility, large-area manufacturability, and long-term operational stability. The chemically programmable nature of organic and polymeric materials provides a powerful platform for addressing these challenges. Their tunable molecular structures enable the rational design of functional motifs tailored to the specific needs of different thin-film layers, offering “function-on-demand” capabilities. Such functionalized materials can be engineered to serve as key components in printed flexible transparent electrodes, charge-transport layers, and active layers. By introducing well-defined redox-active units, dynamically cross-linkable groups, self-assembling cores, and moieties that modulate solution viscosity and aggregation behavior, researchers can simultaneously improve mechanical robustness, film uniformity, interfacial energetics, and environmental stability. In this Account, we highlight recent advances in achieving stable, flexible, and large-area pero-SCs and OSCs through use of functionalized organic and polymeric materials, with emphasis on key contributions from our group. We summarize the underlying design principles, elucidate structure–property–performance correlations in representative material systems, and illustrate how functionally tailored molecules can bridge the gap between molecular-level design and device-level performance. Finally, we offer our perspective on remaining challenges and future research directions toward practical implementation of flexible and scalable perovskite and organic photovoltaics.","PeriodicalId":72040,"journal":{"name":"Accounts of materials research","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147696121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From Materials to Devices: An Engineering Perspective on Designing Gallium-Based Liquid Metal Bioelectronics","authors":"Moo Hyun Kim, Jae-Hyun Lee, Jang-Ung Park","doi":"10.1021/accountsmr.5c00349","DOIUrl":"https://doi.org/10.1021/accountsmr.5c00349","url":null,"abstract":"Gallium-based liquid metals (LMs) are rapidly revolutionizing the field of soft and stretchable electronics, especially within the rapidly evolving biomedical sector. It has excellent biocompatibility, near-zero vapor pressure, and viscosity similar to that of water. It also has one of the highest surface tensions of any liquid at room temperature. However, it can adopt an adaptive shape form because a thin solid oxide skin forms spontaneously when exposed to oxygen. With the increasing need for flexible electronic devices capable of seamlessly interfacing with biological systems, LM offers unparalleled advantages due to their unique combination of metallic conductivity, fluidic flexibility, and inherent low mechanical modulus. The potential of these materials to dramatically enhance device functionality and comfort in wearable and implantable technologies has positioned them at the forefront of emerging bioelectronic solutions. Despite these attractive properties, integrating gallium-based LMs into practical electronic devices remains a considerable challenge, primarily due to intrinsic material behaviors such as high surface tension, instantaneous oxide layer formation, and difficulties in adhering effectively to target substrates. Successfully overcoming these limitations is critical not only for achieving reliable functionality but also for fully realizing the transformative potential of LM microfabrication technologies.","PeriodicalId":72040,"journal":{"name":"Accounts of materials research","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147696122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stimuli-Responsive Polymeric Nanosystems for Precision Cancer Nanovaccines","authors":"Kang Xia, Xin Li, Chao Qi, Xikuang Yao, Wei Huang, Xiqun Jiang","doi":"10.1021/accountsmr.5c00355","DOIUrl":"https://doi.org/10.1021/accountsmr.5c00355","url":null,"abstract":"The development of appealing cancer vaccines marks a significant advancement in precision cancer immunotherapy. Its core mechanism involves delivering tumor antigens to activate host dendritic cells (DCs), thereby initiating and amplifying specific T-cell immune responses to be capable of recognizing and eliminating cancer cells. However, the clinical efficacy of this approach faces several major challenges, including tumor heterogeneity and immune evasion mechanisms within the tumor immunosuppressive microenvironment (TIME). Furthermore, traditional delivery systems often lack spatiotemporal control and fail to ensure the efficient uptake of antigens and adjuvants by lymph node-resident DCs, thereby limiting the generation of effective immune responses. To address these limitations, cancer nanovaccines have evolved from single-antigen formulations toward systemic remodeling of the TIME. Modern immunotherapies aim to disrupt the local immunosuppressive state of tumors and establish a self-sustaining antitumor immune cycle. However, the nonspecific systemic distribution of immunomodulatory drugs can readily induce immune-related adverse events, prompting the development of powerful delivery systems with targeted and controlled release properties. In recent years, stimuli-responsive polymeric nanosystems have emerged as intelligent nanoplatforms for drug delivery. These nanosystems can be engineered to maintain the structural stability in circulation, accumulate in tumor regions via an enhanced permeability and retention (EPR) effect, and respond to various stimuli at desired sites. Upon TIME-specific signals or exogenous stimuli, these nanostructures undergo conformational changes or degradation, enabling spatiotemporally controlled release of loaded immune agonists, checkpoint inhibitors, or cytokines. This strategy not only significantly enhances the bioavailability of immunomodulators at target sites and reduces systemic toxicities but also enables the sequential codelivery of synergistic therapeutic agents. As a result, the immunotherapy combined with stimuli-responsive polymeric nanosystems can efficiently transform immunologically “cold” tumor into “hot” tumor, ultimately achieving profound and sustained modulation of the antitumor immune responses.","PeriodicalId":72040,"journal":{"name":"Accounts of materials research","volume":"85 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147695839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can Machine Learning Enhance Reliable Identification of Reactive Species?","authors":"Rui Li, Ruiping Liu","doi":"10.1021/accountsmr.5c00274","DOIUrl":"https://doi.org/10.1021/accountsmr.5c00274","url":null,"abstract":"Figure 1. Current limitations and potential improvements of ML-based RS detection methods. (9) <b>Rui Li</b> is currently pursuing a Ph.D. in Environmental Science and Technology at Tsinghua University. She received a B.E. degree in Resource Recycling Science and Engineering, a B.A. degree in English at Tianjin University of Technology in 2019, and an M.E. degree in Environmental Engineering at Tianjin University in 2022. Her research interests focus on free radical detection and water pollution decontamination. <b>Ruiping Liu</b> is a tenured professor in the School of Environment at Tsinghua University. He received his Ph.D. degree in Municipal Engineering from Harbin Institute of Technology and his Bachelor’s degree in Municipal Engineering from Wuhan University of Technology. Prior to joining Tsinghua University in December 2019, he worked at the Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, where he served as an assistant researcher (2005–2009), associate researcher (2009–2014), and full researcher (2015–2019). His major research interests focus on mechanisms and technologies in water purification and the water–environments–energy nexus. This work was supported by the National Natural Science Foundation of China (Grants U21A20160, 52192683, and 52300051), the Beijing Outstanding Young Scientist Program (JWZQ20240101005), and the Tsinghua University Initiative Scientific Research Program (20233080005). The authors acknowledge Jing-Hang Wu and Wenwei Li from the University of Science and Technology of China, Xin Yang from Sun Yat-sen University, and Chang Xu and Bo Tang from Shandong Normal University for valuable discussions and proofreading this Viewpoint. This article references 11 other publications. This document has been updated Click for further information. This article has not yet been cited by other publications.","PeriodicalId":72040,"journal":{"name":"Accounts of materials research","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147630850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Designed Synthesis of One-Dimensional van der Waals Heterostructures","authors":"Miaoyu Lu,Yongjia Zheng,Shigeo Maruyama,Rong Xiang","doi":"10.1021/accountsmr.5c00309","DOIUrl":"https://doi.org/10.1021/accountsmr.5c00309","url":null,"abstract":"ConspectusThe development of two-dimensional (2D) materials and their van der Waals (vdW) heterostructures has substantially advanced research in low-dimensional physics and stimulated the exploration of related devices. Further reducing the dimensionality to the one-dimensional (1D) limit often gives rise to more pronounced confinement effects, thereby creating new opportunities for electronic, optoelectronic, and energy-related applications. In this context, 1D vdW heterostructures are typically constructed by assembling 2D counterparts into heteronanotube architectures with coaxial core-shell geometries, while the concept has also been extended to nanotubes encapsulating nanochains, nanowires, or nanoribbons. Compared with their 2D counterparts, 1D systems exhibit strong radial confinement and curvature-induced effects, which together endow them with unique optical, electrical, and thermal properties. The 1D geometry enhances the anisotropy of light-matter interactions and facilitates the efficient axial transport of charge carriers and energy. Meanwhile, the fully encapsulated core-shell configuration effectively suppresses environmental perturbations, providing an ideal platform for probing intrinsic material properties and improving device stability. Accordingly, this Account summarizes recent progress in the field of 1D vdW heterostructures, highlighting representative contributions from our group together with those from many research teams worldwide with the aim of systematically reviewing the current research landscape and outlining future directions. First, the Account presents designed synthesis strategies for 1D vdW heterostructures from the perspectives of component regulation, structure modulation, and orientation control, emphasizing that rational construction of heterostructure composition and architecture can be achieved through designed synthesis. To facilitate a better understanding of the formation process, the Account then discusses the growth mechanism of 1D vdW heterostructures, pointing out that the growth of the outer shells generally follows an open-end growth mode, while no pronounced chiral correlation was observed between different shells. By coaxially integrating distinct 1D building blocks, 1D vdW heterostructures preserve the intrinsic properties of individual components, while their optical, electrical, and thermal behaviors are synergistically influenced by component selection, radial confinement, and interfacial interactions. These emergent physical properties, which distinguish 1D vdW heterostructures from single-component systems or 2D heterostructures, have been preliminarily investigated in several model systems and provide an important physical foundation for subsequent studies. Based on these property advantages, this Account further discusses the application potential of 1D vdW heterostructures in electronic devices and optoelectronic devices as well as catalytic and energy-storage systems. Given that on","PeriodicalId":72040,"journal":{"name":"Accounts of materials research","volume":"112 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147620297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Graphene Oxide: Designing a Functional Smarter Material for Advanced Biomedicine","authors":"Cécilia Ménard-Moyon, Yuta Nishina, Alberto Bianco","doi":"10.1021/accountsmr.5c00362","DOIUrl":"https://doi.org/10.1021/accountsmr.5c00362","url":null,"abstract":"Graphene oxide (GO) has emerged as one of the most extensively studied two-dimensional (2D) materials, thanks to its large surface area and abundance of functional groups, which enable applications across energy, catalysis, electronics, construction, and mobility. Its exceptional dispersibility in water further expands its use in the biomedical field. However, researchers have consistently expressed concerns about the limited control over GO chemical composition and structural heterogeneity. These factors are often overlooked, strongly affecting the reproducibility in both synthesis and applications. Because GO is considered a promising platform for advanced drug delivery, achieving reproducible preparation and precise structural control is essential to make it a reliable alternative to the many nanomaterials currently being explored for nanomedicine.","PeriodicalId":72040,"journal":{"name":"Accounts of materials research","volume":"241 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147599588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Harnessing Metal-Halide Layered Perovskite Structures for Next-Generation Lighting Sources","authors":"Balaji Dhanabalan,Milena P. Arciniegas","doi":"10.1021/accountsmr.5c00246","DOIUrl":"https://doi.org/10.1021/accountsmr.5c00246","url":null,"abstract":"ConspectusAdvances in nanoscale semiconductor materials are enabling next-generation optoelectronic technologies with unprecedented efficiency, spectral control, and device miniaturization. Achieving this potential, however, requires the development of so-called Triple E materials, that is, systems that are environmentally friendly, economically inexpensive, and energetically efficient. Meeting these three criteria simultaneously remains a significant challenge. Metal-halide perovskites have emerged as remarkable semiconductors due to their strong optical absorption, high carrier mobility, long diffusion lengths, defect tolerance, and widely tunable bandgaps. Despite these outstanding properties, their limited ambient and operational stability continues to constrain their large-scale preparation and integration into robust devices.Our research has focused on metal-halide layered perovskites, including Pb-free Sn-based analogues, as promising platforms to address these limitations. In these materials, alternating organic and inorganic layers form natural quantum wells that provide intrinsic electronic and dielectric confinement. This well-defined layered architecture enables tunable, broadband light emission from a single material component, without the need for multiple emissive layers. By avoiding complex multilayer architectures, device fabrication is simplified while interfacial defects, self-absorption effects, and differential degradation pathways are reduced. Moreover, the incorporation of bulky organic cations further enhances environmental stability by increasing hydrophobicity and protecting the inorganic framework from moisture.Beyond structural protection, organic cations play an active role in defining the optoelectronic response. Their size, functionality, and conformation influence octahedral distortions, interlayer spacing, and exciton binding energies. Importantly, we have also shown that interactions between organic cations and solvents during synthesis can influence molecular conformation and octahedral connectivity, thereby directly modulating emission properties and charge transport. This solvent-cation interplay represents a largely unexplored avenue for structural and photophysical tuning.In this Account, we expand upon these advances with a focus on Ruddlesden–Popper organic–inorganic layered perovskites and related structures as efficient and reconfigurable light emitters. We summarize synthetic and design strategies that exploit organic cation engineering and metal substitution to tailor emission across the visible spectrum while addressing toxicity concerns through partial or complete replacement of Pb. The inherent structural versatility of layered perovskites also allows their integration into flexible substrates, reversibly modulating their emission through postsynthetic treatments or mechanical stimuli, broadening their functional scope toward strain-controlled emission.Looking forward, the convergence of artificial ","PeriodicalId":72040,"journal":{"name":"Accounts of materials research","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147585996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}