Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi最新文献

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Acute hepatitis A infection in children: a 20-year experience of a medical center in Southern Taiwan. 儿童急性甲型肝炎感染:台湾南部某医疗中心20年经验。
Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi Pub Date : 2007-06-01 DOI: 10.7097/APT.200706.0131
Yu-Chieh Chen, Li-Tung Huang, Sheng-ming Wang, M. Tiao, Jien-Wei Liu
{"title":"Acute hepatitis A infection in children: a 20-year experience of a medical center in Southern Taiwan.","authors":"Yu-Chieh Chen, Li-Tung Huang, Sheng-ming Wang, M. Tiao, Jien-Wei Liu","doi":"10.7097/APT.200706.0131","DOIUrl":"https://doi.org/10.7097/APT.200706.0131","url":null,"abstract":"BACKGROUND\u0000Taiwan is currently nonendemic for hepatitis A infection, but sporadic cases are reported occasionally. The presenting symptoms of acute hepatitis A (AHA) infection in children are often nonspecific and may be easily misdiagnosed as general gastrointestinal illness.\u0000\u0000\u0000METHODS\u0000We conducted this study to identify the relevant presenting symptoms and laboratory findings of AHA in children. The medical records of all patients younger than 18 years old admitted to Kaohsiung Chang Gang Memorial Hospital from July 1986 to June 2004 under the diagnosis of AHA were reviewed. There were 29 pediatric patients admitted with the diagnosis of AHA, including 16 male patients and 13 female patients.\u0000\u0000\u0000RESULTS\u0000Poor appetite, malaise, abdominal pain, vomiting and fever were the leading constitutional symptoms. Jaundice and tea-colored urine were the most relevant hepatobiliary presentations. Elevation of aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, direct and indirect bilirubin was common, although other hematology and biochemistry examinations were within normal limits on most occasions. There was no mortality in our series. A slightly increasing prevalence of AHA was noted over the two decades of the study period, although it was not statistically significant.\u0000\u0000\u0000CONCLUSIONS\u0000Our results found that children with AHA tended to present with non-specific gastrointestinal symptoms and acute liver function deterioration. Elevation of hepatic aminotransferase and alkaline phosphatase with cholestasis was common.","PeriodicalId":7156,"journal":{"name":"Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2007-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90358543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Childhood occipital epileptic syndromes in Taiwan: clinical characteristics and outcomes. 台湾儿童枕部癫痫综合征:临床特征与结果。
Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi Pub Date : 2007-06-01 DOI: 10.7097/APT.200706.0112
Inn-Chi Lee, Peng-Cheng Fang, Yung-Jung Chen
{"title":"Childhood occipital epileptic syndromes in Taiwan: clinical characteristics and outcomes.","authors":"Inn-Chi Lee, Peng-Cheng Fang, Yung-Jung Chen","doi":"10.7097/APT.200706.0112","DOIUrl":"https://doi.org/10.7097/APT.200706.0112","url":null,"abstract":"BACKGROUND\u0000The present study aimed to elucidate the clinical characteristics and outcomes of three types of occipital epileptic syndromes: early-onset and late-onset childhood epilepsy with occipital paroxysm (ECEOP and LCEOP) and symptomatic occipital epilepsy (SOLE).\u0000\u0000\u0000METHODS\u0000We retrospectively reviewed the medical records of 54 children (18 ECEOP, 10 LCEOP, and 26 SOLE) and compared the clinical features, EEG findings, treatments, and outcomes among these patients.\u0000\u0000\u0000RESULTS\u0000Nocturnal seizures occurred in 55% of the patients with ECEOP, whereas of those with LCEOP and SOLE, 80% and 61% had diurnal seizures, respectively (P = 0.04). Status epilepticus was more common in the ECEOP group, less in LCEOP. Autonomic auras were more common in the SOLE group than in the other two groups. Secondary generalized seizure was often found in the SOLE group (P = 0.03). EEG findings in 72% of the ECEOP group, 60% of the LCEOP group, and 19.2% in the SOLE group were changeable and became to be normal after 5 years of follow-up. Slow EEG background activity was more evident in the SOLE group than in the other two groups. The prognoses of these groups of patients were different. The ECEOP group had the best, and the SOLE group had the worst.\u0000\u0000\u0000CONCLUSIONS\u0000These findings suggest that some clinical features of these three syndromes differ from each other, which may provide clinicians a basis for determining the appropriate diagnosis in children with one of these childhood occipital epileptic syndromes.","PeriodicalId":7156,"journal":{"name":"Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2007-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88900568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Steroid use in sepsis-induced conjugated hyperbilirubinemia: report of one case. 使用类固醇治疗败血症引起的结合性高胆红素血症:1例报告。
Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi Pub Date : 2007-06-01 DOI: 10.7097/APT.200706.0146
Jinn-Li Wang, T. Ou, Chun‐Nan Chen, E. Shen
{"title":"Steroid use in sepsis-induced conjugated hyperbilirubinemia: report of one case.","authors":"Jinn-Li Wang, T. Ou, Chun‐Nan Chen, E. Shen","doi":"10.7097/APT.200706.0146","DOIUrl":"https://doi.org/10.7097/APT.200706.0146","url":null,"abstract":"We report a girl with acute lymphoblastic leukemia who developed severe conjugated hyperbilirubinemia (total bilirubin 34.32 mg/dl, direct bilirubin 26.94 mg/dl) following gram-negative (Escherichia coli ) sepsis. Despite broad-spectrum antibiotics, her hyperbilirubinemia progressed. Her mental status deteriorated and steroid therapy (hydrocortisone 8 mg/kg/d) was initiated. Her condition then recovered rapidly. Based on our findings, we suggest that steroid may help to treat progressive conjugated hyperbilirubinemia due to gram-negative sepsis.","PeriodicalId":7156,"journal":{"name":"Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2007-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81489322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcome of myasthenia gravis mothers and their infants. 重症肌无力母亲及其婴儿的预后。
Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi Pub Date : 2007-06-01 DOI: 10.7097/APT.200706.0141
I. Cheng, Cheng‐Hui Lin, Ming-I. Lin, Jing-Sheng Lee, H. Chiu, S. Mu
{"title":"Outcome of myasthenia gravis mothers and their infants.","authors":"I. Cheng, Cheng‐Hui Lin, Ming-I. Lin, Jing-Sheng Lee, H. Chiu, S. Mu","doi":"10.7097/APT.200706.0141","DOIUrl":"https://doi.org/10.7097/APT.200706.0141","url":null,"abstract":"BACKGROUND\u0000The aim of this retrospective study was to assess neonatal outcomes of pregnant women with myasthenia gravis (MG).\u0000\u0000\u0000METHODS\u0000Pregnant women with MG who were treated in our hospital over an 8-year period were enrolled. Data relating to the course of the mother's MG (including the anti-acetylcholine receptor antibody (anti-AchR) titer and drug dosage), delivery mode, delivery course, puerperium period, and neonatal outcomes were obtained from the medical records.\u0000\u0000\u0000RESULTS\u0000Twelve women with MG had 13 pregnancies in our hospital from January 1997 to December 2005. None of the mothers needed intensive care. Two patients delivered vaginally, and ten delivered by cesarean section. Fourteen infants were born at an average gestational age of 37.2 +/- 2.0 weeks; their average birth weight was 2838.6 +/- 724.2 g. Two neonates (14.2%) had a congenital anomaly. Transitory neonatal myasthenia gravis (NMG) was diagnosed in one infant (7.1%).\u0000\u0000\u0000CONCLUSIONS\u0000In our study, MG exacerbations occurred in 38.5% of the patients. Postpartum, all MG patients experienced deterioration except one patient who deteriorated in the first trimester with a concomitant upper airway tract infection. Only 1 of the 14 neonates developed transient NMG; the incidence of transient NMG was lower than that previously reported. There was no correlation between the occurrence of NMG and the maternal anti-AChR titer. The cesarean section rate was approximately 33%; this high rate of elective cesarean sections in these MG patients could have prevented the occurrence of some of the complications related to vaginal delivery.","PeriodicalId":7156,"journal":{"name":"Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2007-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83540541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Acute hepatitis A in children. 儿童急性甲型肝炎。
Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi Pub Date : 2007-06-01 DOI: 10.7097/APT.200706.0105
Hung-Chang Lee
{"title":"Acute hepatitis A in children.","authors":"Hung-Chang Lee","doi":"10.7097/APT.200706.0105","DOIUrl":"https://doi.org/10.7097/APT.200706.0105","url":null,"abstract":"","PeriodicalId":7156,"journal":{"name":"Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2007-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74721003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perinatal and infant health outcomes among neonates born to aboriginal parents in Taiwan. 台湾原住民父母所生新生儿围产期及婴儿健康状况。
Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi Pub Date : 2007-06-01 DOI: 10.7097/APT.200706.0135
Yu-Hsun Chang, Pau-Chung Chen, C. Hsieh, S. Jeng, H. Liao, Yidi Su, Shio‐Jean Lin, H. Chou, Yi-Ping Lin, W. Hsieh
{"title":"Perinatal and infant health outcomes among neonates born to aboriginal parents in Taiwan.","authors":"Yu-Hsun Chang, Pau-Chung Chen, C. Hsieh, S. Jeng, H. Liao, Yidi Su, Shio‐Jean Lin, H. Chou, Yi-Ping Lin, W. Hsieh","doi":"10.7097/APT.200706.0135","DOIUrl":"https://doi.org/10.7097/APT.200706.0135","url":null,"abstract":"BACKGROUND\u0000Poor health outcomes among neonates born to aborigines has been reported in many countries. This study was aimed to examine the nationwide characteristics of live births, adverse birth outcomes, and age-specific mortality among neonates born to non-aboriginal and aboriginal parents in Taiwan.\u0000\u0000\u0000METHODS\u0000All neonates born alive during the period of 2000 to 2003 in Taiwan were included. The adverse birth outcomes including low birth weight, preterm, and small-for-gestational-age births, and age-specific mortality were obtained. Logistic regression analysis was used to estimate odds ratios for parental ethnicity in relation to birth outcomes, while Cox's proportional hazards regression models were used to estimate hazard ratios for parental ethnicity in relation to age-specific infant deaths.\u0000\u0000\u0000RESULTS\u0000A total of 947,317 live births were included that consisted of 9,381 born to aboriginal mothers, 6,429 born to aboriginal fathers, and 15,354 born to aboriginal parents. There was a gradual increase in the risk of having a baby with low birth weight, preterm, or small for gestational age born to the four parental aboriginal ethnicity groups: non-aboriginal parents, aboriginal mother only, aboriginal father only, and aboriginal parents. Similar trends were also found for early neonatal, neonatal, and infant mortalities after stratification of residential areas. The neonates born to both aboriginal parents with residence in rural or mountain areas were at highest risk of adverse birth outcomes and age-specific mortality.\u0000\u0000\u0000CONCLUSIONS\u0000Our results demonstrated that aboriginality and residential area are important risk factors for adverse perinatal and infant outcomes.","PeriodicalId":7156,"journal":{"name":"Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2007-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82382583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Clinical and laboratory characteristics of type 1 diabetes in children and adolescents: experience from a medical center. 儿童和青少年1型糖尿病的临床和实验室特征:来自医疗中心的经验
Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi Pub Date : 2007-06-01 DOI: 10.7097/APT.200706.0119
W. Ting, Chi‐Yu Huang, F. Lo, Chen-Mei Hung, Chia-Jung Chan, Hsin-Jung Li, Chao-Hsu Lin, Hung-Chang Lee, Yann-Jinn Lee
{"title":"Clinical and laboratory characteristics of type 1 diabetes in children and adolescents: experience from a medical center.","authors":"W. Ting, Chi‐Yu Huang, F. Lo, Chen-Mei Hung, Chia-Jung Chan, Hsin-Jung Li, Chao-Hsu Lin, Hung-Chang Lee, Yann-Jinn Lee","doi":"10.7097/APT.200706.0119","DOIUrl":"https://doi.org/10.7097/APT.200706.0119","url":null,"abstract":"BACKGROUND\u0000The incidence of type 1 diabetes (T1D) is increasing rapidly worldwide, predominantly in younger individuals. We developed a checklist of all symptoms of T1D reported in the literature and compared the completeness of the recording of symptoms at initial presentation before and after the checklist was adopted.\u0000\u0000\u0000METHODS\u0000We retrospectively reviewed the records of patients newly diagnosed with T1D from January 1, 1979 through September 30, 2006 to assess the presenting features and test the usefulness of a symptom checklist in evaluating the history on presentation. The checklist was incorporated into the records as of October 1, 1994.\u0000\u0000\u0000RESULTS\u0000Of the 304 patients identified, 130 (43%) had checklists in the charts. There were 146 (48%) boys, 98 (32%) who were diagnosed under the age of 6 years, and 198 (65%) presented with diabetic ketoacidosis (DKA). Records with a checklist noted diabetic symptoms that were subtle and easily ignored more often than records without the checklist. As compared with those diagnosed at an older age, patients diagnosed at < or = 6 years were more likely to be male, have DKA and a shorter symptom duration, and report more episodes of preceding viral infection and dyspnea. Patients with DKA also had a shorter symptom duration.\u0000\u0000\u0000CONCLUSIONS\u0000A diabetic symptom checklist was helpful in identifying clinical diabetic symptoms and signs which were otherwise easily ignored. Younger children were more likely to have a shorter symptom duration and a higher incidence of DKA.","PeriodicalId":7156,"journal":{"name":"Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2007-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73378047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
Discriminant analysis of serum inflammatory biomarkers which differentiate pediatric appendicitis from other acute abdominal diseases. 小儿阑尾炎与其他急性腹部疾病的血清炎症生物标志物鉴别分析。
Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi Pub Date : 2007-06-01 DOI: 10.7097/APT.200706.0125
K. Lin, Han-Ping Wu, Chin-Yi Huang, Ching‐Yuang Lin, Chin-Fu Chang
{"title":"Discriminant analysis of serum inflammatory biomarkers which differentiate pediatric appendicitis from other acute abdominal diseases.","authors":"K. Lin, Han-Ping Wu, Chin-Yi Huang, Ching‐Yuang Lin, Chin-Fu Chang","doi":"10.7097/APT.200706.0125","DOIUrl":"https://doi.org/10.7097/APT.200706.0125","url":null,"abstract":"BACKGROUND\u0000Other acute abdominal diseases in children can confound the signs and symptoms of appendicitis, resulting in misdiagnosis and unnecessary appendectomy. In this study, we used discriminant analysis of serum inflammatory biomarkers to determine which acute abdominal diseases could mimic appendicitis, and further analyzed these diseases based on different age groups.\u0000\u0000\u0000METHODS\u0000We prospectively collected 417 patients aged from 4 to 18 years with clinically suspected acute appendicitis in the pediatric emergency department. We selected the significantly higher serum biomarkers for appendicitis as the discriminating variables. Furthermore, we analyzed the definitive diagnoses of patients with normal appendices who could not be predicted by discriminant analysis.\u0000\u0000\u0000RESULTS\u0000Patients with acute appendicitis had significantly higher leukocyte counts (p < 0.01), neutrophil counts, (p < 0.01) and C-reactive protein concentrations (p < 0.01 ) than those with normal appendices. The discriminant power of these three serum biomarkers in acute appendicitis was 76 percent. Acute abdominal diseases which mimicked appendicitis included acute gastroenteritis, nonspecific abdominal pain, urinary tract infection, and upper respiratory infection with gastrointestinal upset.\u0000\u0000\u0000CONCLUSIONS\u0000Serum biomarkers may serve as helpful discriminators to predict the presence of pediatric appendicitis. But, some acute abdominal diseases mimicking appendicitis should be considered during differential diagnosis of acute appendicitis to avoid making misdiagnosis and performing unnecessary appendectomy.","PeriodicalId":7156,"journal":{"name":"Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2007-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79752901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Discriminant analysis of serum inflammatory biomarkers which differentiate pediatric appendicitis from other acute abdominal diseases. 小儿阑尾炎与其他急性腹部疾病的血清炎症生物标志物鉴别分析。
Kung-Chen Lin, Han-Ping Wu, Chin-Yi Huang, Ching-Yuang Lin, Chin-Fu Chang
{"title":"Discriminant analysis of serum inflammatory biomarkers which differentiate pediatric appendicitis from other acute abdominal diseases.","authors":"Kung-Chen Lin,&nbsp;Han-Ping Wu,&nbsp;Chin-Yi Huang,&nbsp;Ching-Yuang Lin,&nbsp;Chin-Fu Chang","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Other acute abdominal diseases in children can confound the signs and symptoms of appendicitis, resulting in misdiagnosis and unnecessary appendectomy. In this study, we used discriminant analysis of serum inflammatory biomarkers to determine which acute abdominal diseases could mimic appendicitis, and further analyzed these diseases based on different age groups.</p><p><strong>Methods: </strong>We prospectively collected 417 patients aged from 4 to 18 years with clinically suspected acute appendicitis in the pediatric emergency department. We selected the significantly higher serum biomarkers for appendicitis as the discriminating variables. Furthermore, we analyzed the definitive diagnoses of patients with normal appendices who could not be predicted by discriminant analysis.</p><p><strong>Results: </strong>Patients with acute appendicitis had significantly higher leukocyte counts (p < 0.01), neutrophil counts, (p < 0.01) and C-reactive protein concentrations (p < 0.01 ) than those with normal appendices. The discriminant power of these three serum biomarkers in acute appendicitis was 76 percent. Acute abdominal diseases which mimicked appendicitis included acute gastroenteritis, nonspecific abdominal pain, urinary tract infection, and upper respiratory infection with gastrointestinal upset.</p><p><strong>Conclusions: </strong>Serum biomarkers may serve as helpful discriminators to predict the presence of pediatric appendicitis. But, some acute abdominal diseases mimicking appendicitis should be considered during differential diagnosis of acute appendicitis to avoid making misdiagnosis and performing unnecessary appendectomy.</p>","PeriodicalId":7156,"journal":{"name":"Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2007-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27029558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute hepatitis A infection in children: a 20-year experience of a medical center in Southern Taiwan. 儿童急性甲型肝炎感染:台湾南部某医疗中心20年经验。
Yu-Chieh Chen, Li-Tung Huang, Sheng-Ming Wang, Mao-Meng Tiao, Jien-Wei Liu
{"title":"Acute hepatitis A infection in children: a 20-year experience of a medical center in Southern Taiwan.","authors":"Yu-Chieh Chen,&nbsp;Li-Tung Huang,&nbsp;Sheng-Ming Wang,&nbsp;Mao-Meng Tiao,&nbsp;Jien-Wei Liu","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Taiwan is currently nonendemic for hepatitis A infection, but sporadic cases are reported occasionally. The presenting symptoms of acute hepatitis A (AHA) infection in children are often nonspecific and may be easily misdiagnosed as general gastrointestinal illness.</p><p><strong>Methods: </strong>We conducted this study to identify the relevant presenting symptoms and laboratory findings of AHA in children. The medical records of all patients younger than 18 years old admitted to Kaohsiung Chang Gang Memorial Hospital from July 1986 to June 2004 under the diagnosis of AHA were reviewed. There were 29 pediatric patients admitted with the diagnosis of AHA, including 16 male patients and 13 female patients.</p><p><strong>Results: </strong>Poor appetite, malaise, abdominal pain, vomiting and fever were the leading constitutional symptoms. Jaundice and tea-colored urine were the most relevant hepatobiliary presentations. Elevation of aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, direct and indirect bilirubin was common, although other hematology and biochemistry examinations were within normal limits on most occasions. There was no mortality in our series. A slightly increasing prevalence of AHA was noted over the two decades of the study period, although it was not statistically significant.</p><p><strong>Conclusions: </strong>Our results found that children with AHA tended to present with non-specific gastrointestinal symptoms and acute liver function deterioration. Elevation of hepatic aminotransferase and alkaline phosphatase with cholestasis was common.</p>","PeriodicalId":7156,"journal":{"name":"Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2007-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27029562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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