Steroid use in sepsis-induced conjugated hyperbilirubinemia: report of one case.

Jinn-Li Wang, T. Ou, Chun‐Nan Chen, E. Shen
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引用次数: 0

Abstract

We report a girl with acute lymphoblastic leukemia who developed severe conjugated hyperbilirubinemia (total bilirubin 34.32 mg/dl, direct bilirubin 26.94 mg/dl) following gram-negative (Escherichia coli ) sepsis. Despite broad-spectrum antibiotics, her hyperbilirubinemia progressed. Her mental status deteriorated and steroid therapy (hydrocortisone 8 mg/kg/d) was initiated. Her condition then recovered rapidly. Based on our findings, we suggest that steroid may help to treat progressive conjugated hyperbilirubinemia due to gram-negative sepsis.
使用类固醇治疗败血症引起的结合性高胆红素血症:1例报告。
我们报告了一位患有急性淋巴细胞白血病的女孩,她在革兰氏阴性(大肠杆菌)败血症后出现了严重的结合性高胆红素血症(总胆红素34.32 mg/dl,直接胆红素26.94 mg/dl)。尽管使用广谱抗生素,她的高胆红素血症仍有进展。患者精神状态恶化,开始类固醇治疗(氢化可的松8mg /kg/d)。随后,她的病情迅速恢复。基于我们的研究结果,我们建议类固醇可能有助于治疗由革兰氏阴性败血症引起的进行性结合性高胆红素血症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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