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Acta radiologica: therapy, physics, biology最新文献

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Effect of chemical protectors on the response of the intestine to roentgen or fission neutron irradiation. 化学保护剂对肠道对放射性或裂变中子辐照反应的影响。
Acta radiologica: therapy, physics, biology Pub Date : 1976-10-01 DOI: 10.3109/02841867609131774
C P Sigdestad, A M Connor, R M Scott
{"title":"Effect of chemical protectors on the response of the intestine to roentgen or fission neutron irradiation.","authors":"C P Sigdestad,&nbsp;A M Connor,&nbsp;R M Scott","doi":"10.3109/02841867609131774","DOIUrl":"https://doi.org/10.3109/02841867609131774","url":null,"abstract":"<p><p>The monosodium salt S-1-(2-hydroxy-3-amino) propylphosphorothioic acid (WR-77913) and S-2-amino ethylisothiuronium-Br-HBr (AET) were tested for protective effects against 4 MeV roentgen irradiation and fission neutrons in the mouse intestine. The parameters tested were intestinal crypt survival, lethality and intestinal crypt cellularity. The results showed both compounds to be good protectors in animals. The crypt survival curve for roentgen-irradiated mice treated with AET was parallel to that of the untreated group and was displaced to the right by 4.88 Gy (488 rad). Protection from neutron irradiation was less effective with a displacement of only 0.69 Gy (69 rad). Pretreatment with WR-77913 increased the slope of the crypt survival curve in roentgen-irradiated mice. This was also seen to a much less extent in neutron-irradiated animals. The displacements of the curves (at 50 per cent crypt survival) were found to be 5.15 and 1.02 Gy (515 and 102 rad) for roentgen and neutron irradiation, respectively. The lethality experiments showed a dose modification factor (DMF) of 1.42 for both drug-tested groups of roentgen-irradiated mice. The dose modification factors for fission neutron irradiated mice were 1.48 and 1.2 for WR-77913 and AET-treated mice, respectively. The effect of these protectors of crypt cellularity is also discussed.</p>","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"15 5","pages":"401-9"},"PeriodicalIF":0.0,"publicationDate":"1976-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867609131774","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12187159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
Evaluation of the clinical use of TLD. TLD的临床应用评价。
Acta radiologica: therapy, physics, biology Pub Date : 1976-10-01 DOI: 10.3109/02841867609131779
B I Rudén
{"title":"Evaluation of the clinical use of TLD.","authors":"B I Rudén","doi":"10.3109/02841867609131779","DOIUrl":"https://doi.org/10.3109/02841867609131779","url":null,"abstract":"<p><p>The relative light output per Gy in water for conventional roentgen radiation (20-190 kV), high energy roentgen radiation (6 and 42 MV) and electrons between 2.2 and 34.5 MeV relative to 60 Co gamma radiation is reported for different kinds of LiF dosemeters. The routine use of LiF dosemeters for a wide range of dosimetry applications in radiation therapy, the handling of the dosemeters to obtain high accuracy and the usefulness of making patient dose measurements are described.</p>","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"15 5","pages":"447-64"},"PeriodicalIF":0.0,"publicationDate":"1976-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867609131779","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12012815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 36
Influence of steroid hormones on the carcinogenicity of 90Sr. 类固醇激素对90Sr致癌性的影响。
Acta radiologica: therapy, physics, biology Pub Date : 1976-10-01 DOI: 10.3109/02841867609131776
A Nilsson, A Broomé-Karlsson
{"title":"Influence of steroid hormones on the carcinogenicity of 90Sr.","authors":"A Nilsson,&nbsp;A Broomé-Karlsson","doi":"10.3109/02841867609131776","DOIUrl":"https://doi.org/10.3109/02841867609131776","url":null,"abstract":"<p><p>Groups of female CBA-mice were given 90Sr (14.8 kBq/g-0.4muCi/g--bodyweight) alone or in combination with polyestrodiolphosphate, methylprednisolone or nortestosterone, respectively. When 90Sr was given in the first combination, the frequency of osteosarcomas was significantly increased whereas the tumour latency time was decreased compared to mice given 90Sr alone. In combination with nortestosterone such effects were not found, whereas the combination 90Sr + methylprednisolone resulted in a strong reduction of the osteosarcoma incidence and a prolonged tumour latency time. The latter experiment was repeated in a larger experiment whereby the results were confirmed.</p>","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"15 5","pages":"417-26"},"PeriodicalIF":0.0,"publicationDate":"1976-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867609131776","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12249994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Build-up effects at air cavities measured with thin thermoluminescent dosimeters. 用薄热释光剂量计测量空气腔中的累积效应。
Acta radiologica: therapy, physics, biology Pub Date : 1976-10-01 DOI: 10.3109/02841867609131777
B Nilsson, P O Schnell
{"title":"Build-up effects at air cavities measured with thin thermoluminescent dosimeters.","authors":"B Nilsson,&nbsp;P O Schnell","doi":"10.3109/02841867609131777","DOIUrl":"https://doi.org/10.3109/02841867609131777","url":null,"abstract":"<p><p>The build-up and build-down situation around air cavities of various size in a polystyrene phantom was evaluated by measurements with LiF-Teflon disks with a thickness of about 1.6 X 10(-2) kg/m2. The measurements demonstrate that when irradiating with two opposed beams the surface dose at the cavity (depth 39 mm) is 74% of the maximum dose for 60 Co, 77% for 6 MV and 87% for 42 MV roentgen radiation.</p>","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"15 5","pages":"427-32"},"PeriodicalIF":0.0,"publicationDate":"1976-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867609131777","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12187160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 22
Late effects on rabbit brain morphology and monoamine metabolites produced by 60C0-irradiation. 60c0辐照对家兔脑形态及单胺代谢产物的后期影响。
Acta radiologica: therapy, physics, biology Pub Date : 1976-10-01 DOI: 10.3109/02841867609131778
R Adolfsson, C G Gottfries, O Hassler, B E Roos, B Winblad
{"title":"Late effects on rabbit brain morphology and monoamine metabolites produced by 60C0-irradiation.","authors":"R Adolfsson,&nbsp;C G Gottfries,&nbsp;O Hassler,&nbsp;B E Roos,&nbsp;B Winblad","doi":"10.3109/02841867609131778","DOIUrl":"https://doi.org/10.3109/02841867609131778","url":null,"abstract":"<p><p>Twenty-three rabbits were exposed with 60Co irradiation over the skull. Nineteen of the animals received 29.6 Gy over the right hemisphere and 4 animals received 20 Gy over both hemispheres. Six months after the exposure the cncentrations of 5-hydroxyindolacetic acid (5-HIAA) and homovanillic acid (HVA) in seven different brain regions were assayed. No significant differences in the levels of these monoamine metabolites as compared to nonirradiated control animals were found. In contrast to discrete biochemical changes, a relatively marked parenchymal destruction was demonstrated by means of light microscopy, microangiography and scanning electron microscopy of the vessels, which exhibited telangiectases, fibrinoid necroses and thrombosis due to the late effects of irradiation.</p>","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"15 5","pages":"433-46"},"PeriodicalIF":0.0,"publicationDate":"1976-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867609131778","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12187161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Blurring quality in spiral tomography. 螺旋断层成像中的模糊质量。
Acta radiologica: therapy, physics, biology Pub Date : 1976-10-01 DOI: 10.3109/02841867609131780
G Harding, M J Day
{"title":"Blurring quality in spiral tomography.","authors":"G Harding,&nbsp;M J Day","doi":"10.3109/02841867609131780","DOIUrl":"https://doi.org/10.3109/02841867609131780","url":null,"abstract":"<p><p>In view of the close relationship which exists between image aberrations and the form of the transfer function, the transfer functions of some different types of spiral tomographic movements have been calculated numerically. The results allow prediction of a type of spiral movement which yields blurring of favourable quality. The validity of this approach has been demonstrated experimentally, by comparing the blurring characteristics of tomographs with single and multiple circular movements. When the radii of the circles in the latter case are chosen with reference to the form of the transfer function, a marked improvement in blurring quality is apparent.</p>","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"15 5","pages":"465-80"},"PeriodicalIF":0.0,"publicationDate":"1976-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867609131780","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12187162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Telecobalt therapy for malignant lung tumours. 电钴治疗恶性肺肿瘤。
Acta radiologica: therapy, physics, biology Pub Date : 1976-10-01 DOI: 10.3109/02841867609131773
N Ghilezan, N Milea, S Tamburlini
{"title":"Telecobalt therapy for malignant lung tumours.","authors":"N Ghilezan,&nbsp;N Milea,&nbsp;S Tamburlini","doi":"10.3109/02841867609131773","DOIUrl":"https://doi.org/10.3109/02841867609131773","url":null,"abstract":"<p><p>The authors present the results of telecobalt therapy in 194 patients with malignant lung tumours treated between 1967 and 1971. The 3- and 5-year survivals were 9.7 and 5.4% respectively, with an average survival of 15 months. The results obtained depend on the microscopy, the clinical staging and on the irradiation techniques possible; several prognostic groups may be distinguished.</p>","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"15 5","pages":"394-400"},"PeriodicalIF":0.0,"publicationDate":"1976-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867609131773","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11404736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Pulmonary contraction following 60Co irradiation of mammary carcinoma. 60Co照射后乳腺癌的肺收缩。
Acta radiologica: therapy, physics, biology Pub Date : 1976-08-01 DOI: 10.3109/02841867609131970
T Oppedal, A Kolbenstvedt
{"title":"Pulmonary contraction following 60Co irradiation of mammary carcinoma.","authors":"T Oppedal,&nbsp;A Kolbenstvedt","doi":"10.3109/02841867609131970","DOIUrl":"https://doi.org/10.3109/02841867609131970","url":null,"abstract":"<p><p>Pulmonary contraction, as measured by elevation of the right superior interlobar fissure, was investigated in 38 patients with carcinoma of the right breast, treated by radical mastectomy followed by irradiation with 60Co. Contraction of the right upper lobe was observed to extend over a minimum of four years although at a diminishing rate.</p>","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"15 4","pages":"329-36"},"PeriodicalIF":0.0,"publicationDate":"1976-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867609131970","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12165900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Experiments on radiation-induced tumor. Theoretical view-points. 辐射诱导肿瘤实验。理论中诚信。
Acta radiologica: therapy, physics, biology Pub Date : 1976-08-01 DOI: 10.3109/02841867609131973
K Paasikallio, E Spring, M Salmo
{"title":"Experiments on radiation-induced tumor. Theoretical view-points.","authors":"K Paasikallio,&nbsp;E Spring,&nbsp;M Salmo","doi":"10.3109/02841867609131973","DOIUrl":"https://doi.org/10.3109/02841867609131973","url":null,"abstract":"","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"15 4","pages":"357-68"},"PeriodicalIF":0.0,"publicationDate":"1976-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867609131973","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12165903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Local prognosis after combined external and interstitial radiation therapy for carcinoma of the tongue. 舌癌外、间质联合放疗后的局部预后。
Acta radiologica: therapy, physics, biology Pub Date : 1976-08-01 DOI: 10.3109/02841867609131968
T Inoue, H Fuchihata, T Wada, Y Shigematsu
{"title":"Local prognosis after combined external and interstitial radiation therapy for carcinoma of the tongue.","authors":"T Inoue,&nbsp;H Fuchihata,&nbsp;T Wada,&nbsp;Y Shigematsu","doi":"10.3109/02841867609131968","DOIUrl":"https://doi.org/10.3109/02841867609131968","url":null,"abstract":"<p><p>Of 36 patients with early carcinoma of the tongue treated with interstitial irradiation, 25 were controlled, 10 recurred and one developed local necrosis. Of 57 advanced cases treated with telecobalt therapy followed by interstitial irradiation, 15 were controlled, 20 recurred and 22 developed local necrosis. The frequency of necrosis following the combined irradiation was unacceptably high. Interstitial therapy alone may be a more adequate method for the primary tumour.</p>","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"15 4","pages":"315-20"},"PeriodicalIF":0.0,"publicationDate":"1976-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867609131968","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12166025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
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