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Acta radiologica: therapy, physics, biology最新文献

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Modification of the biologic dose to normal tissue by daily fraction. Model for calculating normal tissue tolerance. 按日剂量调整正常组织的生物剂量。计算正常组织公差的模型。
Acta radiologica: therapy, physics, biology Pub Date : 1976-12-01
M Wollin, A R Kagan
{"title":"Modification of the biologic dose to normal tissue by daily fraction. Model for calculating normal tissue tolerance.","authors":"M Wollin,&nbsp;A R Kagan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A method to predict normal tissue injury is proposed that includes high daily doses and unusual times successfully by calculating a new value called BIR (Biologic Index of Reaction). BIR and NSD were calculated for various normal tissue reactions. With the aid of statistical correlation techniques it is found that the BIR model is better than the NSD model in predicting radiation myelopathy and vocal edema and as good as NSD in predicting rib fracture. Neither model predicts pericardial effusion. In no case were the results of BIR inferior to those of NSD.</p>","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"15 6","pages":"481-92"},"PeriodicalIF":0.0,"publicationDate":"1976-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12212430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anti-oestrogen therapy of advanced mammary carcinoma. 晚期乳腺癌的抗雌激素治疗。
Acta radiologica: therapy, physics, biology Pub Date : 1976-12-01 DOI: 10.3109/02841867609131975
H Westerberg, B Nordenskjöld, A de Schryver, G Notter
{"title":"Anti-oestrogen therapy of advanced mammary carcinoma.","authors":"H Westerberg,&nbsp;B Nordenskjöld,&nbsp;A de Schryver,&nbsp;G Notter","doi":"10.3109/02841867609131975","DOIUrl":"https://doi.org/10.3109/02841867609131975","url":null,"abstract":"<p><p>Forty mg daily of tamoxifen (Nolvadex) was administered orally to 89 patients with advanced soft tissue mammary carcinoma. At two months 43 per cent of the patients responded. At 6, 12 and 18 months, 42, 35 and 32 per cent, respectively, were still responding to therapy. The side effects were limited, fatique being the most frequent complaint. Oestrogen dependent side effects were not encountered. The therapeutic effect of tamoxifen is similar to that of oestrogen, but the side effects are less.</p>","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"15 6","pages":"513-8"},"PeriodicalIF":0.0,"publicationDate":"1976-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867609131975","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12212431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
Bladder and intestinal injuries following radiation therapy of carcinoma of the uterine cervix. 子宫颈癌放射治疗后膀胱及肠道损伤。
Acta radiologica: therapy, physics, biology Pub Date : 1976-12-01 DOI: 10.3109/02841867609131978
J E Johnsson
{"title":"Bladder and intestinal injuries following radiation therapy of carcinoma of the uterine cervix.","authors":"J E Johnsson","doi":"10.3109/02841867609131978","DOIUrl":"https://doi.org/10.3109/02841867609131978","url":null,"abstract":"<p><p>The frequency of serious complications in the bladder and intestines in 674 patients irradiated for carcinoma of the cervix using three different techniques is reported. The first technique was the Stockholm technique, which gave 5% severe complications. In the other two, the patients received primarily external irradiation without central shielding, complemented with intracavitary treatment. Difficulties in the Stockholm technique and in techniques combining external high-voltage and intracavitary treatment were taken into account, and the frequency of serious complications decreased to less than 1%.</p>","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"15 6","pages":"541-9"},"PeriodicalIF":0.0,"publicationDate":"1976-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867609131978","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12015578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Scanning electron microscopy of cells in the lymph of the human thoracic duct in advanced malignancies. 晚期恶性肿瘤患者胸导管淋巴细胞的扫描电镜。
Acta radiologica: therapy, physics, biology Pub Date : 1976-12-01 DOI: 10.3109/02841867609131976
O Dahlbäck, H Dencker, C H Håkansson, L H Lindberg, C von Mecklenburg
{"title":"Scanning electron microscopy of cells in the lymph of the human thoracic duct in advanced malignancies.","authors":"O Dahlbäck,&nbsp;H Dencker,&nbsp;C H Håkansson,&nbsp;L H Lindberg,&nbsp;C von Mecklenburg","doi":"10.3109/02841867609131976","DOIUrl":"https://doi.org/10.3109/02841867609131976","url":null,"abstract":"<p><p>At scanning electron microscopy of cells from the lymph of the thoracic duct, collected by cannulation of patients with malignant tumours of different types, lymphocytes and red blood cells were found, but few malignant cells. The latter came from patients with pulmonary carcinoma and mammary carcinoma with lung metastases. Various abnormal shapes of the red blood cells were observed, possibly due to extrinsic factors such as administered drugs of abnormal metabolites from the malignant disease. The lymphocytes had no consistent pathologic shape, but appeared to act as immunologic, active cells against the malignant cells in the thoracic lymph.</p>","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"15 6","pages":"519-28"},"PeriodicalIF":0.0,"publicationDate":"1976-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867609131976","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12212432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiation sensitizing effect of diamide on human cells cultivated in vitro. 二胺对体外培养人细胞的辐射增敏作用。
Acta radiologica: therapy, physics, biology Pub Date : 1976-12-01 DOI: 10.3109/02841867609131980
E O Pettersen, R Oftebro, T Brustad
{"title":"Radiation sensitizing effect of diamide on human cells cultivated in vitro.","authors":"E O Pettersen,&nbsp;R Oftebro,&nbsp;T Brustad","doi":"10.3109/02841867609131980","DOIUrl":"https://doi.org/10.3109/02841867609131980","url":null,"abstract":"Human cells of line NHIK 3025 were irradiated suspended in growth medium (E2a) in absence and presence of diamide under aerobic and extremely hypoxic (less than 4 ppm O2) conditions. A sensitizing effect of diamide was found for doses exceeding 8 Gy (800 rad) on cells irradiated under extremely hypoxic conditions in presence of diamide of concentration 200 micrometer, whereas no significant effect was observed for 20 micrometer.","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"15 6","pages":"551-9"},"PeriodicalIF":0.0,"publicationDate":"1976-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867609131980","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12212433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Forming of electron beams from a betatron by foil scatterers. 由箔散射体从电子加速器形成电子束。
Acta radiologica: therapy, physics, biology Pub Date : 1976-12-01 DOI: 10.3109/02841867609131974
A P Kozlov, V A Shishov
{"title":"Forming of electron beams from a betatron by foil scatterers.","authors":"A P Kozlov,&nbsp;V A Shishov","doi":"10.3109/02841867609131974","DOIUrl":"https://doi.org/10.3109/02841867609131974","url":null,"abstract":"<p><p>The technique of forming electron beams by one scattering foil and one compensating foil is discussed. This method provides a means for producing large-size uniform dose distributions with much smaller losses in dose rate as compared with conventional beam forming by one foil. Moreover, the energy losses involved in this process and the background [corrected] of concomitant bremsstrahlung are much less. A technique of calculation to determine approximate parameters of the compensating foils is described.</p>","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"15 6","pages":"493-512"},"PeriodicalIF":0.0,"publicationDate":"1976-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867609131974","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12015575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
Effects on the cardiovascular system of irradiation for malignant lymphoma. 恶性淋巴瘤放疗对心血管系统的影响。
Acta radiologica: therapy, physics, biology Pub Date : 1976-12-01 DOI: 10.3109/02841867609131977
L E Larsson, J Lindahl, B Unsqaard
{"title":"Effects on the cardiovascular system of irradiation for malignant lymphoma.","authors":"L E Larsson,&nbsp;J Lindahl,&nbsp;B Unsqaard","doi":"10.3109/02841867609131977","DOIUrl":"https://doi.org/10.3109/02841867609131977","url":null,"abstract":"<p><p>In 55 patients irradiated for malignant lymphoma the complaints were recorded as well as ECG, blood pressure, exercise test and heart volume before, during and one and 6 months following treatment. ECG abnormalities and fall in blood pressure occurred during treatment. Reduced physical working capacity was found one month after treatment. After 6 months all parameters had returned to pretreatment levels. Attention should be paid to the considerable reduction in blood pressure that does occur in some cases during treatment.</p>","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"15 6","pages":"529-40"},"PeriodicalIF":0.0,"publicationDate":"1976-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867609131977","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12015576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Mantle treatment of Hodgkin's disease. Results and side effects. 霍奇金氏病的地幔疗法结果和副作用。
Acta radiologica: therapy, physics, biology Pub Date : 1976-10-01 DOI: 10.3109/02841867609131771
G Svahn-Tapper, L Baldetorp, T Landberg
{"title":"Mantle treatment of Hodgkin's disease. Results and side effects.","authors":"G Svahn-Tapper,&nbsp;L Baldetorp,&nbsp;T Landberg","doi":"10.3109/02841867609131771","DOIUrl":"https://doi.org/10.3109/02841867609131771","url":null,"abstract":"<p><p>Eighty-seven patients were treated with the mantle technique for Hodgkin's disease. Usually 40 Gy in 27 fractions in two series over 71 days were given. A local recurrence was diagnosed in 3 of 87 patients. An analysis of radiation reactions of the lung tissue, heart and pericardium, and spinal cord is reported. It is recommended to give mantle treatment for Hodgkin's disease over a relatively long period of time such as in split-course in two series.</p>","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"15 5","pages":"369-86"},"PeriodicalIF":0.0,"publicationDate":"1976-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867609131771","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12187157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Whole-body autoradiography of 99Tcm-labelled ethylene-1-hydroxy-1, 1-diphosphonate (EHDP) in young rats. 99tcm标记的乙烯-1-羟基- 1,1 -二膦酸酯(EHDP)在幼鼠体内的全身放射自显影。
Acta radiologica: therapy, physics, biology Pub Date : 1976-10-01 DOI: 10.3109/02841867609131775
M Rohlin
{"title":"Whole-body autoradiography of 99Tcm-labelled ethylene-1-hydroxy-1, 1-diphosphonate (EHDP) in young rats.","authors":"M Rohlin","doi":"10.3109/02841867609131775","DOIUrl":"https://doi.org/10.3109/02841867609131775","url":null,"abstract":"<p><p>The distribution of 99Tcm after intraperitoneal injection of 99Tcm-labelled ethylene-1-hydroxy-1, 1-diphosphonate (EHDP) in young albino rats was investigated by whole-body autoradiography. The distribution was characterized by a rapid and high uptake in bone and dentine, a rapid but moderate uptake in the urinary system and a slow and slight uptake in liver and spleen.</p>","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"15 5","pages":"410-6"},"PeriodicalIF":0.0,"publicationDate":"1976-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867609131775","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12012814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Biopsy of the nasopharynx as a staging procedure in Hodgkin's disease. 作为何杰金氏病分期程序的鼻咽活检。
Acta radiologica: therapy, physics, biology Pub Date : 1976-10-01 DOI: 10.3109/02841867609131772
A Biörklund, E Cavallin-Ståhl, T Landberg, L G Lindberg, M Akerman
{"title":"Biopsy of the nasopharynx as a staging procedure in Hodgkin's disease.","authors":"A Biörklund,&nbsp;E Cavallin-Ståhl,&nbsp;T Landberg,&nbsp;L G Lindberg,&nbsp;M Akerman","doi":"10.3109/02841867609131772","DOIUrl":"https://doi.org/10.3109/02841867609131772","url":null,"abstract":"<p><p>Biopsy of the nasopharynx was perfomred in 45 patients with Hodgkin's disease as part of the pretherapeutic staging. Seven of the 45 (16%) had microscopic abnormalities in the nasopharynx compatible with Hodgkin's disease. Such abnormalities occurred even in the absence of local ENT-symptoms or signs, and they could not be predicted from the microscopic type of lymph node biopsy, stage of disease or general presentation. A generous biopsy of the nasopharynx is recommended to be included in the staging procedures in Hodgkin's disease.</p>","PeriodicalId":7139,"journal":{"name":"Acta radiologica: therapy, physics, biology","volume":"15 5","pages":"387-93"},"PeriodicalIF":0.0,"publicationDate":"1976-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841867609131772","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12187158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
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