Moscow University Physics Bulletin最新文献_第4页

Study of Single Antigen–Antibody Interactions on a Silicon Surface in Biosensors Based on Field-Effect Transistors with a Nanowire Channel 基于场效应晶体管的纳米线通道生物传感器硅表面单抗原-抗体相互作用研究

IF 0.4 4区物理与天体物理

Moscow University Physics Bulletin Pub Date : 2025-07-13 DOI: 10.3103/S0027134925700249

D. E. Presnov, G. V. Presnova, I. I. Tsiniaikin, G. V. Nibudin, O. V. Snigirev, A. S. Trifonov, M. M. Ulyashova, V. A. Krupenin, M. Yu. Rubtsova

{"title":"Study of Single Antigen–Antibody Interactions on a Silicon Surface in Biosensors Based on Field-Effect Transistors with a Nanowire Channel","authors":"D. E. Presnov, G. V. Presnova, I. I. Tsiniaikin, G. V. Nibudin, O. V. Snigirev, A. S. Trifonov, M. M. Ulyashova, V. A. Krupenin, M. Yu. Rubtsova","doi":"10.3103/S0027134925700249","DOIUrl":"10.3103/S0027134925700249","url":null,"abstract":"To develop highly sensitive biosensors based on field-effect transistors with a silicon nanowire channel (FET), single interactions of antibodies with prostate-specific antigen (PSA) on the surface of pure silicon modified with 5 nm gold nanoparticles were studied. A digital immunocomplex registration method using scanning electron microscopy was employed, where 25 nm gold nanoparticles served as antibody visualizing labels. A specialized algorithm was developed to calculate the nanoparticle density on the silicon surface. Various methods of chemical silicon modification using silanes (3-glycidoxypropyltrimethoxysilane (GOPS), 3-mercaptopropyltrimethoxysilane (GOPS-SH), and 3-aminopropyltriethoxysilane (APTES)), bifunctional reagents, and polyethylene glycol were applied to investigate covalent antibody immobilization. It has been shown that chemical modification methods using GOPS are characterized by a lower detection limit for prostate-specific antigen (PSA)—a biomarker of prostate tumors. Biosensor structures based on field-effect transistors with nanowire channels, whose surfaces were modified by two different methods using GOPS, were fabricated, and their pH sensitivity was studied. It has been demonstrated that the modification method using GOPS-SH is characterized by a maximum pH sensitivity of 70 mV/pH and is the most promising for the development of highly sensitive biosensors for biomarker detection.","PeriodicalId":711,"journal":{"name":"Moscow University Physics Bulletin","volume":"80 2","pages":"320 - 329"},"PeriodicalIF":0.4,"publicationDate":"2025-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145165248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Generation of Triangular Meshes Using Potential Energy Minimization Method 基于势能最小化法的三角网格生成

IF 0.4 4区物理与天体物理

Moscow University Physics Bulletin Pub Date : 2025-07-13 DOI: 10.3103/S0027134925700262

K. A. Novikov, D. A. Konyaev, T. A. Novikova

引用次数: 0

Search for Bosonic Dark Matter Using the iDREAM Neutrino Detector at the Kalinin Nuclear Power Plant 加里宁核电站用iDREAM中微子探测器寻找玻色子暗物质

IF 0.4 4区物理与天体物理

Moscow University Physics Bulletin Pub Date : 2025-07-13 DOI: 10.3103/S0027134925700377

A. V. Abramov, R. R. Alyev, M. B. Gromov, I. N. Zhutikov, K. K. Kiselev, S. M. Kiselev, A. V. Konstantinov, D. S. Kuznetsov, E. A. Litvinovich, I. N. Machulin, A. E. Murchenko, A. M. Nemeryuk, R. R. Nugmanov, A. Yu. Oralbaev, D. V. Popov, A. A. Rastimeshin, M. A. Strizh, V. A. Khvatov, A. S. Chepurnov, D. A. Chmykhalo, A. V. Etenko

引用次数: 0

Atomic Mechanism of the Transformation between BCC and HCP Phases in Zirconium under Pressure 锆中BCC相与HCP相在压力下转变的原子机理

IF 0.4 4区物理与天体物理

Moscow University Physics Bulletin Pub Date : 2025-07-13 DOI: 10.3103/S0027134925700304

R. I. Sinyakov, M. P. Belov

{"title":"Atomic Mechanism of the Transformation between BCC and HCP Phases in Zirconium under Pressure","authors":"R. I. Sinyakov, M. P. Belov","doi":"10.3103/S0027134925700304","DOIUrl":"10.3103/S0027134925700304","url":null,"abstract":"Using first-principles methods for calculating crystal energy, the atomic mechanism of the transformation between the BCC ((beta)) and HCP ((alpha)) phases of zirconium at low temperature has been investigated. An accurate two-parameter geometric approach has been developed to describe the lattice transformation via the Burgers mechanism. The proposed description method accounts for changes in atomic volume and the shape of the crystal lattice during the transformation. Using the proposed transformation description, potential energy surfaces of zirconium during the BCC–HCP transformation were constructed in the pressure range from 0 to 25 GPa with a step of 5 GPa. The gradient descent method was used to determine the minimum energy paths along the potential energy surfaces. Analysis of the results revealed a strong dependence of the shape of the energy surfaces and the minimum energy path on pressure. As the pressure increases to 25 GPa, the shape of the potential energy surface of zirconium undergoes a critical change, and a structure appears on the surface with an energy 10.5 meV lower than that of the HCP phase. Comparison of the calculated results obtained using the developed two-parameter transformation description method with one-parameter analogues from the literature demonstrated the inconsistency of the latter as a tool for studying atomic mechanisms of phase transitions.","PeriodicalId":711,"journal":{"name":"Moscow University Physics Bulletin","volume":"80 2","pages":"314 - 319"},"PeriodicalIF":0.4,"publicationDate":"2025-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145165479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Resistive Gas Sensor Based on Mesoporous MoS({}_{mathbf{2}}) Films 基于介孔MoS ({}_{mathbf{2}})薄膜的电阻式气体传感器

IF 0.4 4区物理与天体物理

Moscow University Physics Bulletin Pub Date : 2025-07-13 DOI: 10.3103/S0027134925700274

A. B. Loginov, M. M. Kuvatov, I. V. Sapkov, R. R. Ismagilov, V. I. Kleshch, A. N. Obraztsov

{"title":"Resistive Gas Sensor Based on Mesoporous MoS({}_{mathbf{2}}) Films","authors":"A. B. Loginov, M. M. Kuvatov, I. V. Sapkov, R. R. Ismagilov, V. I. Kleshch, A. N. Obraztsov","doi":"10.3103/S0027134925700274","DOIUrl":"10.3103/S0027134925700274","url":null,"abstract":"Semiconducting mesoporous films with a large specific surface area are of interest for the development of gaseous medium sensors. In this study, such sensors were fabricated using a material synthesized on bulk substrates via a chemical reaction between gaseous H({}_{2})S and Mo vapour obtained by thermal evaporation. X-ray photoelectron spectroscopy confirmed that the obtained layers consist of MoS({}_{2}). Scanning electron microscopy (SEM) revealed that the films deposited on different substrates are an array of crystallites with thicknesses of a few nanometers and transversal dimensions of several hundred nanometers. The MoS({}_{2}) crystallites are predominantly oriented perpendicular to the substrate surface and are spaced by distances of several tens of nanometers. The surface electrical resistance of the mesoporous MoS({}_{2}) layers was measured as a function of water vapour and ammonia vapour concentrations in the surrounding medium. It was discovered that the electrical resistance of MoS({}_{2}) decreases with increasing relative humidity and ammonia vapour concentration. The current response profile to changes in the concentration of these components in air exhibits an exponential time dependence with two characteristic time constants. For NH({}_{3}) vapour, the characteristic rise times are 0.9 and 17 s, while the fall times are 1.2 and 29 s. In the case of H({}_{2})O vapour, the characteristic rise times are 4 and 45 s, and the fall times are 1.25 and 42 s. The mechanisms underlying the increase in electrical conductivity of MoS({}_{2}) films with increasing humidity and ammonia vapour concentration are discussed.","PeriodicalId":711,"journal":{"name":"Moscow University Physics Bulletin","volume":"80 2","pages":"299 - 305"},"PeriodicalIF":0.4,"publicationDate":"2025-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145165537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electromagnetic Form Factors of the Deuteron in the Dibaryon Model of the (mathbf{NN}) Interaction (mathbf{NN})相互作用双重子模型中氘核的电磁形状因子

IF 0.4 4区物理与天体物理

Moscow University Physics Bulletin Pub Date : 2025-07-13 DOI: 10.3103/S0027134925700250

M. N. Platonova, I. T. Obukhovsky

引用次数: 0

Numerical Models of Nonlinear Acoustic Wave Propagation in Medical Ultrasound Problems and Certain Applications of Aeroacoustics and Underwater Acoustics 医学超声问题中非线性声波传播的数值模型及其在气动声学和水声中的某些应用

IF 0.4 4区物理与天体物理

Moscow University Physics Bulletin Pub Date : 2025-07-13 DOI: 10.3103/S0027134925700316

P. V. Yuldashev, O. A. Sapozhnikov, M. M. Karzova, S. A. Tsysar, A. V. Kvashennikova, E. O. Konnova, V. A. Khokhlova

引用次数: 0

Reservoir Network Based on Single Impurity Atoms in Silicon 基于硅中单杂质原子的储层网络

IF 0.4 4区物理与天体物理

Moscow University Physics Bulletin Pub Date : 2025-07-13 DOI: 10.3103/S0027134925700420

A. S. Andreeva, A. S. Trifonov, V. V. Shorokhov, D. E. Presnov, O. V. Snigirev, V. A. Krupenin

{"title":"Reservoir Network Based on Single Impurity Atoms in Silicon","authors":"A. S. Andreeva, A. S. Trifonov, V. V. Shorokhov, D. E. Presnov, O. V. Snigirev, V. A. Krupenin","doi":"10.3103/S0027134925700420","DOIUrl":"10.3103/S0027134925700420","url":null,"abstract":"This study is aimed at solving the problem of experimental implementation and investigation of single-electron reservoir networks with As impurity atoms in a quasi-two-dimensional near-surface layer of a solid-state matrix based on silicon-on-insulator (SOI) material. The study of electron transport in the fabricated experimental structures revealed the presence of horizontal Coulomb blockade sections in the current–voltage characteristics (CVC) typical of single-electron transport. The shape of the recorded CVC between a pair of selected control electrodes of the reservoir network significantly depended on the potentials of the remaining surrounding electrodes, which modified the structure of the conductive channels passing through the impurity centers. By adjusting the control voltages and utilizing the intrinsic nonlinearity of the system of disordered single As impurity atoms, which possesses an enormous state space, it was possible to demonstrate the feasibility of implementing a tunable nanoscale current switch and the logical functions ‘‘NOT,’’ ‘‘AND,’’ and ‘‘OR’’ in the single-electron reservoir network. A vector tuning method was employed to determine the required configuration of the reservoir network for the implementation of functional elements.","PeriodicalId":711,"journal":{"name":"Moscow University Physics Bulletin","volume":"80 2","pages":"277 - 285"},"PeriodicalIF":0.4,"publicationDate":"2025-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145164581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

FeSe({}_{mathbf{0.5}})Te({}_{mathbf{0.5}}) Films on Glass with CeO({}_{mathbf{2}}) Doping FeSe ({}_{mathbf{0.5}})掺杂CeO ({}_{mathbf{2}})的({}_{mathbf{0.5}})玻璃薄膜

IF 0.4 4区物理与天体物理

Moscow University Physics Bulletin Pub Date : 2025-07-13 DOI: 10.3103/S002713492570033X

A. V. Petrov, O. V. Snigirev, E. A. Ovchenkov, Yu. V. Blinova, N. V. Porokhov, A. R. Shevchenko, D. A. Chareev, A. G. Maresov

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A Simple Finite-Dimensional Model of the Metastable State 亚稳态的简单有限维模型

IF 0.4 4区物理与天体物理

Moscow University Physics Bulletin Pub Date : 2025-07-13 DOI: 10.3103/S0027134925700298

A. I. Dubikovsky, P. K. Silaev

引用次数: 0