流行病学期刊(英文)最新文献

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Analysis of the Spatial Distribution Characteristics of Abnormal Bone Density in Male Long-Distance Runners from Different Regions in China 我国不同地区男子长跑运动员骨密度异常的空间分布特征分析
流行病学期刊(英文) Pub Date : 2021-02-05 DOI: 10.4236/OJEPI.2021.111008
Longxing Fan, W. Zhang, Huanhuan Cui, Yanqing Liu, Ziquan Liu
{"title":"Analysis of the Spatial Distribution Characteristics of Abnormal Bone Density in Male Long-Distance Runners from Different Regions in China","authors":"Longxing Fan, W. Zhang, Huanhuan Cui, Yanqing Liu, Ziquan Liu","doi":"10.4236/OJEPI.2021.111008","DOIUrl":"https://doi.org/10.4236/OJEPI.2021.111008","url":null,"abstract":"Objective: To investigate the occurrence pattern of abnormal bone density in male long-distance runners from several different regions of China, and provide a basis for elucidating the influences of geo-environmental differences on bone density. Methods: We employed a set of well-designed exclusion-inclusion criteria to recruit study subjects, in which compounding factors were managed and regional environmental traits were fully incorporated. WHO (World Health Organization) criteria for the diagnosis of osteoporosis were then used to examine the subjects to determine occurrence of abnormal bone density. The resulting data were analyzed using methods of spatial statistics, which included several approaches, such as spatial autocorrelation, hot spot analysis, and Geodetector Software analysis, to depict and analyze the spatial distribution of abnormal bone density in male athletes from different regions in China, thereby investigating the influences of geo-environmental factors (e.g., temperature, humidity, and altitude) on bone density. Results: A total of 685 subjects were effectively examined in this study, including 486 with normal bone density, 185 with osteopenia, and 14 with osteoporosis. Spatial distribution analysis revealed that the distribution of subjects with abnormal bone density overall exhibited a pattern indicating that the level of abnormal bone density in the eastern regions was higher than that in the western regions and that the levels of abnormal bone density in the southern and northern regions were higher than that in the middle regions. Spatial autocorrelation analysis revealed a Moran’s I = 0.136, Z-score = 1.114, and P value = 0.265 and indicated that the athletes with abnormal bone density were randomly distributed in each region. Hot spot analysis revealed that Tibet and Qinghai displayed distributions of cold spots. Geodetector Software analysis yielded a Q value for annual average temperature of 1.000 and a corresponding P value of 0.000, and the results revealed that temperature significantly affected bone density and that altitude, relative humidity, sunlight hours, and temperature variations displayed synergistic effects on bone density and could diminish the influences of temperature on bone density. Conclusion: Our data revealed that different regions displayed different distribution patterns of abnormal bone density such that the level in the eastern regions was higher than that in the western ones and that the levels in the southern and northern regions were higher than that in the middle regions; specifically, the provinces of Yunnan, Heilongjiang, Hainan, and Inner Mongolia had high rates of abnormal bone density, whereas Tibet and Qinghai had relatively good conditions of bone density. Our data suggested that suitable temperature changes and appropriate levels of temperature variations can decrease the occurrence rates of osteopenia and osteoporosis.","PeriodicalId":71174,"journal":{"name":"流行病学期刊(英文)","volume":"11 1","pages":"80-91"},"PeriodicalIF":0.0,"publicationDate":"2021-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43759876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidemiological Characteristics of COVID-19 Confirmed Cases in Muscat Governorate, Sultanate of Oman 阿曼苏丹国马斯喀特省新冠肺炎确诊病例流行病学特征
流行病学期刊(英文) Pub Date : 2021-02-04 DOI: 10.4236/OJEPI.2021.111006
Lamya Al Balushi, Fatma Al Fahdi, Thamra Al Ghafri, Mohammed Amin, J. Singh, Balqees Al Siyabi, M. A. Kalbani, Mayasa Al Kindi, F. A. Balushi, Haleema Al Ghazaili, Malak Al Alwai, S. Mashari, H. A. Kindi, A. Rumhi, Ibtisam Al Shidhani, Zainb Al Balushi, P. Kurup, F. Ajmi
{"title":"Epidemiological Characteristics of COVID-19 Confirmed Cases in Muscat Governorate, Sultanate of Oman","authors":"Lamya Al Balushi, Fatma Al Fahdi, Thamra Al Ghafri, Mohammed Amin, J. Singh, Balqees Al Siyabi, M. A. Kalbani, Mayasa Al Kindi, F. A. Balushi, Haleema Al Ghazaili, Malak Al Alwai, S. Mashari, H. A. Kindi, A. Rumhi, Ibtisam Al Shidhani, Zainb Al Balushi, P. Kurup, F. Ajmi","doi":"10.4236/OJEPI.2021.111006","DOIUrl":"https://doi.org/10.4236/OJEPI.2021.111006","url":null,"abstract":"Introduction: The coronavirus disease 2019 (COVID-19) was declared as pandemic by WHO by March 11th. First case reported in Oman was on 24th February 2020 and later the country went through stages of epidemic progression. This study describes the sociodemographic and epidemiological characteristics of confirmed COVID-19 cases in Muscat governorate and related outcomes. Materials and Methods: This is a descriptive, exploratory analysis of all lab confirmed COVID 19 cases that were reported from 1st February to 31st May 2020. Data for the study was primarily extracted from notifications system established for surveillance (Tarassud). Secondary data sources were, contact listings and hospital medical records. Results: 11,648 initial cases of confirmed COVID-19 infections were included. The mean age was 35 years, 84.7% (N = 9862) were males, 25.9% (N = 3017) were Omanis, and 74.1% (N = 8631) were expatriates of which Indian origin were the majority (37%). Fever and cough were the most common presentations (46.3% and 29.5% respectively). Diabetes and hypertension were the most common comorbidities (4.9% and 4.6% respectively). Hospital admission was required for 7% (N = 811) of the total reported cases, out of them 171 cases (21%) were admitted to ICU, where 107 (13.2%) were ventilated. The case fatality rate (CFR) was 0.9%. 158 clusters containing 2949 contacts were identified from case records and categorised into 3 groups based on their exposure settings. The incubation period measured was 8 days (IQR 4.0 - 15.0) for workplace, 8 days (IQR 4 - 17) for dormitory and 4 days (IQR 2.0 - 7.0) for family groups. The secondary attack rate (SAR) estimated was 41.6% (95% CI: 0.34 - 0.48), 52% (95% CI: 0.40 - 0.63) and 33% (95% CI: 0.27 - 0.38) for workplace, dormitory and family groups, respectively. Conclusion: Results of this study, determine the transmission trend of COVID-19 in a country with high immigrant population. These findings could be utilised for further response planning in similar settings.","PeriodicalId":71174,"journal":{"name":"流行病学期刊(英文)","volume":"11 1","pages":"56-69"},"PeriodicalIF":0.0,"publicationDate":"2021-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44450766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Customer Satisfaction at Galen House, Bulawayo, Zimbabwe, 2019 2019年,津巴布韦布拉瓦约Galen House的客户满意度
流行病学期刊(英文) Pub Date : 2021-02-04 DOI: 10.4236/OJEPI.2021.111007
Munekayi Padingani, N. Dube, S. Chiwanda, N. Gombe, Gerald Shambira, T. Juru, P. Nsubuga, M. Tshimanga
{"title":"Customer Satisfaction at Galen House, Bulawayo, Zimbabwe, 2019","authors":"Munekayi Padingani, N. Dube, S. Chiwanda, N. Gombe, Gerald Shambira, T. Juru, P. Nsubuga, M. Tshimanga","doi":"10.4236/OJEPI.2021.111007","DOIUrl":"https://doi.org/10.4236/OJEPI.2021.111007","url":null,"abstract":"Introduction: Healthcare industries have seen recent movements towards continuous quality improvement. The healthcare regulators shifted towards a market-driven approach of turning patient satisfaction surveys into a quality improvement tool for overall organizational performance. Data concerning this has remained limited in private sector in Zimbabwe. Thus, this study aims to determine patients and health workers perception about health services offered at Galen house in order to enable the institution to come up with evidence-based interventions to improve the quality of healthcare services. Methods: This was a descriptive cross sectional study. It was a mixed qualitative and quantitative study involving data collected from patients/ guardians and health workers at Galen House from January 2019 to March of the same year. Data was analysed using Microsoft Excel version 2013. Results: There were a total of 270 patients involved into the study. 173 (64%) perceived the waiting before services as good. 213 (79%) perceived the total waiting time as not long. Privacy 215 (80%) and confidentiality 223 (83%) perceived as good by patients. More than 50% of health workers perceived health services offered at Galen House as good. Staff attitude was perceived as good 191 (71%) by patients in contrary to some instance by health workers. Affordability of services was perceived as manageable. Conclusion: The total waiting time was perceived as not long at Galen House. Staff attitude was perceived differently by patients and health workers. Improving those two will contribute to more utilization of services by the community.","PeriodicalId":71174,"journal":{"name":"流行病学期刊(英文)","volume":"11 1","pages":"70-79"},"PeriodicalIF":0.0,"publicationDate":"2021-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44082101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Interrupted Time Series Analysis of COVID-19 Positivity before, during and after Lockdown in Four States of India 印度四个邦封锁前、期间和之后新冠肺炎阳性率的中断时间序列分析
流行病学期刊(英文) Pub Date : 2021-01-05 DOI: 10.4236/ojepi.2021.111005
S. Tetali, G. Jammy, E. Asirvatham, B. R. Kumar, L. Choudhury
{"title":"An Interrupted Time Series Analysis of COVID-19 Positivity before, during and after Lockdown in Four States of India","authors":"S. Tetali, G. Jammy, E. Asirvatham, B. R. Kumar, L. Choudhury","doi":"10.4236/ojepi.2021.111005","DOIUrl":"https://doi.org/10.4236/ojepi.2021.111005","url":null,"abstract":"Objectives: The objective of this study was to examine the impact of large scale non-pharmaceutical interventions on COVID-19 pandemic. Methods: We used interrupted time series analysis (ITS), a quasi-experimental model to evaluate the effect of interventions in four states of India by comparing the COVID-19 positivity before lockdown, during lockdown and opening-up period. Results: The positivity in all the four states declined during lockdown and the trends reversed soon after the lockdown measures were relaxed as the states opened-up. The rate of reduction of positivity was significantly different between states. Between the lockdown and opening-up period, an increase in positivity was recorded in all the states with significant variation between states. Conclusion: The analysis provides conclusive evidence that the lockdown measures had a positive effect in reducing the burden of COVID-19 and establishes a causal relationship.","PeriodicalId":71174,"journal":{"name":"流行病学期刊(英文)","volume":"11 1","pages":"47-55"},"PeriodicalIF":0.0,"publicationDate":"2021-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46976932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
First Hour Initiation of Breast Feeding & Associated Factors, among Mothers at Post Natal Ward in Fort Portal Referral Hospital, Uganda 乌干达门户堡转诊医院产后病房母亲的第一个小时开始母乳喂养及相关因素
流行病学期刊(英文) Pub Date : 2021-01-01 DOI: 10.4236/ojepi.2021.111001
Margaret Rukindo, Mathias Tumwebaze, Elizabeth Manimake Mijumbi
{"title":"First Hour Initiation of Breast Feeding & Associated Factors, among Mothers at Post Natal Ward in Fort Portal Referral Hospital, Uganda","authors":"Margaret Rukindo, Mathias Tumwebaze, Elizabeth Manimake Mijumbi","doi":"10.4236/ojepi.2021.111001","DOIUrl":"https://doi.org/10.4236/ojepi.2021.111001","url":null,"abstract":"Background: Breast milk is recommended as the best feeding option to neonates and infants for it confers immunological benefits that help to reduce neonatal and infant morbidities and mortalities. WHO recommends that all infants should start breast feeding within one hour of birth i.e. early initiation of breast feeding (EIBF). Unfortunately, studies show that less than 40% of infants in resource limited settings Uganda inclusive are initiated on breast feeding practice, with no documented study done in Kabarole district to assess the problem. This study therefore, set out to establish the prevalence and associated factors with the practice of first hour initiation of breast feeding at Fort Portal Regional Hospital, Kabarole district, Uganda. Methods: With a cross-sectional design, we collected data from 330 post natal mothers and their live-born infants at Fort Portal Regional Referral hospital from 5th-20th August 2019. With a standard interviewer administered tool, mothers who initiated breast feeding within the first hour after delivery of their newly born babies responded with yes and those that did not with a no. Prevalence of one hour initiation was got considering infants that were initiated on breast within one hour over the total live birth times 100 to get the percent prevalence. With Stata version 13 software, statistically significant relationships of the predisposing factors were determined at a p-value (p ≤ 0.05) at bivariate and at multivariate regression coefficient. Results: A total of 330 postnatal mothers targeted for this study, 100% response rate was covered. Mothers’ age ranged from 18 - 45 years with mean age 31 SD ± 6. The prevalence of initiation of breast feeding in the first hour of birth was 68%, a third of (32%) mothers had not initiated breast feeding in the first hour. A half (50%) of the direct predisposing factors for non-initiation of timely breastfeeding were due to birth asphyxia, almost a quarter 23% due to mother’s ill health and 7% due mother not being guided by the health worker on what to do. In this study mothers’ knowledge and awareness of the practice were very low at 20% while that of health workers was fair at 53%. Social demographic factors that influence 1st hour breast feeding practice were; young maternal age being less than 34 years, mothers occupation being self-employed (83%) or unemployed (73%) with 3 times higher odds of initiating breastfeeding within 1st (OR = 3, p = 0.003) than working class mothers (civil servants). Marital status of mothers being married (73%) significantly influenced early breastfeeding practice (p = 0.001). Health workers’ knowledge of the practice was significantly associated (OR = 2.7, X2 = 11.32, *p = 0.00078) with enforcement of mother initiation of breast feeding in first hour compared to the less knowledgeable ones. Conclusion: The practice of timely initiation of breastfeeding at Fort Portal Regional Referral hospital at 68.2% was sub-optimal against WHO univer","PeriodicalId":71174,"journal":{"name":"流行病学期刊(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70634225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Knowledge, Attitude and Practice of Adverse Pregnancy Outcomes Prevention among Women of Reproductive Age in Nasarawa Local Government Area, Kano State, Nigeria 尼日利亚卡诺州纳萨拉瓦地方政府区育龄妇女预防不良妊娠结局的知识、态度和做法
流行病学期刊(英文) Pub Date : 2021-01-01 DOI: 10.4236/ojepi.2021.114040
Ismail Bamidele Afolabi, Aremu Abdulmujeeb Babatunde, Salaam Mujeeb, S. Yahaya, Ada Abaku, Ngozi Jane Muonagolu
{"title":"Knowledge, Attitude and Practice of Adverse Pregnancy Outcomes Prevention among Women of Reproductive Age in Nasarawa Local Government Area, Kano State, Nigeria","authors":"Ismail Bamidele Afolabi, Aremu Abdulmujeeb Babatunde, Salaam Mujeeb, S. Yahaya, Ada Abaku, Ngozi Jane Muonagolu","doi":"10.4236/ojepi.2021.114040","DOIUrl":"https://doi.org/10.4236/ojepi.2021.114040","url":null,"abstract":"Background: Adverse pregnancy outcomes continue to contribute substantially to maternal mortality as well as poor maternal and fetal health outcomes whose burden can be reduced by the initiation of preventive behaviors like the uptake of maternal health services. This continuous unacceptably high maternal mortality justifies a need for progressive research to better understand the predictors of the preventive behaviors of women towards adverse pregnancy outcomes. This study was conducted to assess levels of knowledge, attitudes about adverse pregnancy outcomes and preventive practices among women of reproductive age in Nassarawa local government area, Kano State, Nigeria. Me-thodology: The study was a cross-sectional descriptive study that employed a four-sectioned pretested researcher administered questionnaire to collect data on knowledge, attitude and practice of adverse pregnancy outcomes prevention among 164 consenting respondents in Kano State, Nigeria between November 2020 and December 2020. Responses were transformed and computed using SPSS version 26 to generate descriptive statistics. Regression analysis was done to test the degree of association between the predictors and practice of adverse pregnancy outcomes prevention with the level of significance set at a cut-off of p ≤ 0.05. Results: The findings showed tively. The practice of adverse pregnancy outcomes prevention when assessed on a 15-point scale shows that respondents scored a mean of 7.42 ± 8.30 which denotes 53.4% of the level of prevention practice anticipated from the respondents. The study also showed a significant positive association between the level of knowledge (p = 0.010), attitude (p < 0.001) and prevention practice of adverse pregnancy outcomes. Conclusions: The findings reported an average but inadequate knowledge and neutral attitude that predicted unsatisfactory adverse pregnancy outcomes prevention practices among the examined reproductive-aged women, which calls for targeted health education on adverse pregnancy outcomes within the community in order to inform better prevention practices.","PeriodicalId":71174,"journal":{"name":"流行病学期刊(英文)","volume":"692 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70634599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Epidemiology of Self-Harm in the Romanian Juvenile Prison System: A Two-Year Cohort Study 罗马尼亚少年监狱系统中自残的流行病学:一项为期两年的队列研究
流行病学期刊(英文) Pub Date : 2021-01-01 DOI: 10.4236/ojepi.2021.114031
Baias Carmen Valeria, Finnegan-Beckwith Joseph
{"title":"The Epidemiology of Self-Harm in the Romanian Juvenile Prison System: A Two-Year Cohort Study","authors":"Baias Carmen Valeria, Finnegan-Beckwith Joseph","doi":"10.4236/ojepi.2021.114031","DOIUrl":"https://doi.org/10.4236/ojepi.2021.114031","url":null,"abstract":"Background: There is no extensive literature on social predictors of self-harm in the juvenile justice system, over the time of a prisoner’s sentence. Self-harm behavior displays a higher prevalence in prison, 11 to 14 times greater than in the general population. Our study extended the current research in self-harm by examining dynamic factors of self-harm in adolescents over their sentence in the Romanian juvenile prison system. Method: The present research examined longitudinal predictors of self-harm behaviors in 439 adolescent inmates (Mage = 16.21; 5.2% female, 94.8% male), enrolled in prison during 2011-2012, following them for two years. A series of time-to-event analyses were applied to start from the time of the subject’s internment in the juvenile prison system. Results: Findings from the multivariate survival analyses show that adherence to self-harm conduct in prison was consistently influenced by family factors and prison contexts; although low ability to cope with frustration, sensitivity and emotion dysregulation also matter-ed. Keeping the other covariates invariant, serving a prison sentence in a closed regime reduces the probability of remaining free of self-harm events, increasing the monthly hazard of self-harm by a factor of 5.26 on average (HR = 5.26, 95% CI = 2.37 - 11.64) compared to the open regime. Conclusion: A on studies the each in self-harm, according to their emerging needs.","PeriodicalId":71174,"journal":{"name":"流行病学期刊(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70634754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Epidemiological Pattern of Lassa Fever Outbreak in Ondo State, Southwest Nigeria, 2014 to 2019 2014 - 2019年尼日利亚西南部翁多州拉沙热暴发流行病学模式
流行病学期刊(英文) Pub Date : 2021-01-01 DOI: 10.4236/OJEPI.2021.111009
E. Isere, Temioluwa Fuwape, G. Famokun, S. Fagbemi, A. Fatiregun, Nosa Omorogbe, A. Adejugbagbe, T. O. Omoju
{"title":"Epidemiological Pattern of Lassa Fever Outbreak in Ondo State, Southwest Nigeria, 2014 to 2019","authors":"E. Isere, Temioluwa Fuwape, G. Famokun, S. Fagbemi, A. Fatiregun, Nosa Omorogbe, A. Adejugbagbe, T. O. Omoju","doi":"10.4236/OJEPI.2021.111009","DOIUrl":"https://doi.org/10.4236/OJEPI.2021.111009","url":null,"abstract":"Introduction: Annual outbreak of Lassa Fever (LF) has been reported in Ondo State over the years. We analyzed LF surveillance data from January 2014 to December 2019 to describe the epidemiological pattern of the outbreak. Method: Lassa fever dataset from January 2014 to December 2019 was obtained from the State Ministry of Health. Variables analyzed include date of onset of symptom, age, gender, place (Local Government Area, LGA) and outcome of laboratory test. Data were summarized using frequencies, proportions, chart and maps. Results: From January 2014 and December 2019, 2141 suspected LF cases were reported. Of these, 551 cases were laboratory confirmed with 134 deaths recorded. The LF cases (suspected vs. confirmed) reported increased in 2016 (73 vs. 19), 2017 (207 vs. 76), 2018 (452 vs. 159) and 2019 (856 vs. 285) respectively. Most of the confirmed cases (89.5%) were ≥15 years while more than half (53.7%) were males. Prior to 2016, only two LGAs (Owo and Ose) recorded continued transmission of the disease. However, between 2016 and 2019, the disease had spread to 8 neighboring LGAs (P < 0.001) with the CFR declining from 67% in 2015 to 20% in 2019. Conclusion: We found an unusual increase in the suspected LF cases reported between January 2016 and December 2019 with a corresponding increase in the confirmed cases and high annual case fatality rates. Hence, we recommend intensified surveillance activities to enhance timely reporting of cases and laboratory confirmation to ensure early commencement of treatment to reduce the case fatality rate.","PeriodicalId":71174,"journal":{"name":"流行病学期刊(英文)","volume":"11 1","pages":"92-100"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70633883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Evaluation of Perinatal Mortality Surveillance System in the City of Bulawayo, Zimbabwe 津巴布韦布拉瓦约市围产期死亡率监测系统评价
流行病学期刊(英文) Pub Date : 2021-01-01 DOI: 10.4236/OJEPI.2021.112012
Munekayi Padingani, Gladys Marape, Z. Hwalima, L. Takundwa, N. Gombe, Gerald Shambira, T. Juru, M. Tshimanga
{"title":"Evaluation of Perinatal Mortality Surveillance System in the City of Bulawayo, Zimbabwe","authors":"Munekayi Padingani, Gladys Marape, Z. Hwalima, L. Takundwa, N. Gombe, Gerald Shambira, T. Juru, M. Tshimanga","doi":"10.4236/OJEPI.2021.112012","DOIUrl":"https://doi.org/10.4236/OJEPI.2021.112012","url":null,"abstract":"","PeriodicalId":71174,"journal":{"name":"流行病学期刊(英文)","volume":"11 1","pages":"124-134"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70633950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy and Safety Study of CA330 Hemadsorption Device on IL-6 Removal in Septic Patients: Study Protocol of a Multicenter Randomized Controlled Trial CA330血液吸附装置去除脓毒症患者IL-6的有效性和安全性研究:一项多中心随机对照试验的研究方案
流行病学期刊(英文) Pub Date : 2021-01-01 DOI: 10.4236/ojepi.2021.114041
Y. Nie, Zhiyi Jiang, Zi-meng Liu, X. Guan
{"title":"Efficacy and Safety Study of CA330 Hemadsorption Device on IL-6 Removal in Septic Patients: Study Protocol of a Multicenter Randomized Controlled Trial","authors":"Y. Nie, Zhiyi Jiang, Zi-meng Liu, X. Guan","doi":"10.4236/ojepi.2021.114041","DOIUrl":"https://doi.org/10.4236/ojepi.2021.114041","url":null,"abstract":"Background: Sepsis persists to be the leading cause of morbidity and mortality worldwide with the huge cost of health care resources. Besides adequate antibiotics and infectious source control, definitive therapy is still being studied. The activation of multiple proand anti-inflammatory mediators plays a key role in the sepsis process. The application of adsorption may help deactivate and decrease the peak elevation of these mediators in the earlier course of sepsis, when levels of endotoxins and cytokines are extremely high. However, the clinical evidence to support hemadsorption for removing endotoxins and/or pro-inflammatory mediators in sepsis remains incompetent and controversial. In this study protocol, we aimed to test the efficacy of removing cytokines and the safety of a new hemadsorption device, CA330, in septic patients. Design: This is a multicenter randomized controlled clinical trial enrolling 8 tertiary hospitals in China. A total of 144 patients will be randomly divided into the experimental group and the control group according to the ratio of 1:1. The primary endpoint is the reduction rate of IL-6 serum concentration between the initiation of the first adsorption and end with the second adsorption. Discussion: To our knowledge, this clinical trial is the first to evaluate the efficacy and safety of the CA330 hemadsorption device in sepsis patients. Our study will raise the level of evidence for the treatment of sepsis patients with hemadsorption.","PeriodicalId":71174,"journal":{"name":"流行病学期刊(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70634613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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