Cosby G Arnold, Paul Ishimine, Kevan A McCarten-Gibbs, Kenneth Yen, Nisa Atigapramoj, Mohamed Badawy, Irma T Ugalde, Pradip P Chaudhari, Jeffrey S Upperman, Nathan Kuppermann, James F Holmes
{"title":"Performance of individual criteria of the Pediatric Emergency Care Applied Research Network (PECARN) intraabdominal injury prediction rule.","authors":"Cosby G Arnold, Paul Ishimine, Kevan A McCarten-Gibbs, Kenneth Yen, Nisa Atigapramoj, Mohamed Badawy, Irma T Ugalde, Pradip P Chaudhari, Jeffrey S Upperman, Nathan Kuppermann, James F Holmes","doi":"10.1111/acem.15084","DOIUrl":"10.1111/acem.15084","url":null,"abstract":"<p><strong>Objective: </strong>The Pediatric Emergency Care Applied Research Network (PECARN) derived and externally validated a clinical prediction rule to identify children with blunt torso trauma at low risk for intraabdominal injuries undergoing acute intervention (IAI<sup>AI</sup>). Little is known about the risk for IAI<sup>AI</sup> when only one or two prediction rule variables are positive. We sought to determine the risk for IAI<sup>AI</sup> when either one or two PECARN intraabdominal injury rule variables are positive.</p><p><strong>Methods: </strong>We performed a planned secondary analysis of a prospective, multicenter study that included 7542 children (<18 years old) with blunt torso trauma evaluated in six emergency departments from December 2016 to August 2021. Patients with only one or two PECARN rule variables positive were included. The outcome was IAI<sup>AI</sup> (IAI undergoing therapeutic laparotomy, angiographic embolization, blood transfusion, or two or more nights of intravenous fluids).</p><p><strong>Results: </strong>Among the 7542 children enrolled, 2986 (39.6%, 95% confidence interval [CI] 38.5%-40.7%) had one or two PECARN variables positive and were included. Of this subpopulation, 227 (7.6%, 95% CI 6.7%-8.6%) had intraabdominal injuries. In the 1639 patients with only one rule variable positive, 21 (1.3%, 95% CI 0.8%-2.0%) had IAI<sup>AI</sup>. In the 1347 patients with two rule variables positive, 27 (2.0%, 95% CI 1.3%-2.9%) had IAI<sup>AI</sup>. Risk for IAI<sup>AI</sup> for each variable was highest for Glasgow Coma Scale (GCS) score <14 (16/291, 5.5%, 95% CI 3.2%-8.8%) and abdominal wall trauma (three of 321, 0.9%, 95% CI 0.2%-2.7%). Risk for IAI<sup>AI</sup> when two variables were present was highest when decreased breath sounds (three of 44, 6.8%, 95% CI 1.4%-18.7%) and GCS <14 (10/207, 4.8%, 95% CI 2.3%-8.7%) were present with one other variable.</p><p><strong>Conclusions: </strong>Few children with blunt torso trauma and one or two PECARN predictor variables present have IAI<sup>AI</sup>. Those with GCS score <14, however, are at highest risk for IAI<sup>AI</sup>.</p>","PeriodicalId":7105,"journal":{"name":"Academic Emergency Medicine","volume":" ","pages":"643-649"},"PeriodicalIF":3.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12173795/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142969160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Timing the key to meaningful survival: The importance of early epinephrine in cardiac arrest.","authors":"Michael C Perlmutter, Johanna C Moore","doi":"10.1111/acem.70009","DOIUrl":"10.1111/acem.70009","url":null,"abstract":"","PeriodicalId":7105,"journal":{"name":"Academic Emergency Medicine","volume":" ","pages":"708-710"},"PeriodicalIF":3.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143447714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Colleen K Gutman, Antionette McFarlane, Rosemarie Fernandez, K Casey Lion, Paul L Aronson, Carma L Bylund, Nancy Joseph, Maria L Mecias, Carla L Fisher
{"title":"\"He was not listening to hear me\": Parent experiences with communication, inclusion, and marginalization in the pediatric emergency department.","authors":"Colleen K Gutman, Antionette McFarlane, Rosemarie Fernandez, K Casey Lion, Paul L Aronson, Carma L Bylund, Nancy Joseph, Maria L Mecias, Carla L Fisher","doi":"10.1111/acem.15091","DOIUrl":"10.1111/acem.15091","url":null,"abstract":"<p><strong>Objective: </strong>Inequities in pediatric emergency department (ED) care may be influenced by disparities in clinician communication. We sought to examine, from the perspective of parents from marginalized racial and ethnic backgrounds, how clinician-parent communication is characterized during pediatric ED visits.</p><p><strong>Methods: </strong>We conducted and analyzed in-depth semistructured individual interviews with parents of pediatric ED patients from marginalized racial and ethnic backgrounds. We applied a constant comparative method approach to conduct a thematic analysis informed by grounded theory. To ensure rigor, we collected and analyzed data concurrently. We used the patient-centered communication (PCC) framework and the 10 principles of Public Health Critical Race Praxis as sensitizing constructs during analysis. Two coders followed several analytical steps: (1) open coding for concept discovery, (2) grouping concepts into themes, (3) axial coding to identify thematic properties, and (4) identification of exemplar excerpts for rich description. Thematic saturation was based on repetition, recurrence, and forcefulness.</p><p><strong>Results: </strong>Nineteen parents participated. Parents described three clinician communicative behaviors that facilitated their sense of inclusion or marginalization: information exchange, empathic communication, and partnership-building. Parents also stressed the importance of their own proactive communication in facilitating their inclusion. Few participants described experiencing racism during their child's ED visit, yet many did during prior health care encounters, which they connected to their current experience. In particular, parents described how their use of proactive communication was motivated by their past experiences of racism in medical encounters.</p><p><strong>Conclusions: </strong>These narratives demonstrate ways in which experienced racism, both past and present, may inform how parents receive and respond to gaps in PCC. Communication focused interventions that adapt a race-conscious perspective may have a role in promoting health equity.</p>","PeriodicalId":7105,"journal":{"name":"Academic Emergency Medicine","volume":" ","pages":"632-642"},"PeriodicalIF":3.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143254259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Melissa O'Neill, Sheldon Cheskes, Ian R Drennan, Charles Keown-Stoneman, Steve Lin, Brodie Nolan
{"title":"When will we finally listen? A statistical commentary on the inadequate management of missing data in trauma research.","authors":"Melissa O'Neill, Sheldon Cheskes, Ian R Drennan, Charles Keown-Stoneman, Steve Lin, Brodie Nolan","doi":"10.1111/acem.15112","DOIUrl":"10.1111/acem.15112","url":null,"abstract":"","PeriodicalId":7105,"journal":{"name":"Academic Emergency Medicine","volume":" ","pages":"713-715"},"PeriodicalIF":3.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143121800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Justin K Brooten, Jaime L Speiser, Jennifer L Gabbard, David P Miller, Simon A Mahler, Adam S Turner, Rebecca L Omlor, Michelle M Mielke, David M Cline
{"title":"Emergency department early mortality model for patients admitted after presenting to a tertiary medical center emergency department.","authors":"Justin K Brooten, Jaime L Speiser, Jennifer L Gabbard, David P Miller, Simon A Mahler, Adam S Turner, Rebecca L Omlor, Michelle M Mielke, David M Cline","doi":"10.1111/acem.15096","DOIUrl":"10.1111/acem.15096","url":null,"abstract":"<p><strong>Objectives: </strong>Identifying patients in the emergency department (ED) at higher risk for in-hospital mortality can inform shared decision making and goals-of-care discussions. Electronic health record systems allow for integrated multivariable logistic regression (LR) modeling, which can provide early predictions of mortality risk in time for crucial decision making during a patient's initial care. Many commonly used LR models require blood gas analysis values, which are not frequently obtained in the ED. The goal of this study was to develop an all-cause mortality prediction model, derived from commonly collected ED data, which can assess mortality risk early in ED care.</p><p><strong>Methods: </strong>Data were obtained for all patients, age 18 and older, admitted from the ED to Atrium Health Wake Forest Baptist from April 1, 2016, through March 31, 2020. Initial vital signs including heart rate, respiratory rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure, pulse oximetry, weight, body mass index, comprehensive metabolic panel, and a complete blood count were electronically retrieved for all patients. The prediction model was developed using LR. The ED early mortality (EDEM) model was compared with the rapid Emergency Medicine Score (REMS) for performance analysis.</p><p><strong>Results: </strong>A total of 45,004 patients met inclusion criteria, comprising a total of 77,117 admissions. In this cohort, 52.8% of patients were male and 47.2% were female. The model used 35 variables and yielded an area under the receiver operating characteristic curve (AUC) of 0.889 (95% CI 0.874-0.905) with a sensitivity of 0.828 (95% CI 0.791-0.860), a specificity of 0.788 (95% CI 0.783-0.794), a negative predictive value of 0.995 (95% CI 0.994-0.996), and a positive predictive value of 0.084 (95% CI 0.076-0.092). This outperformed REMS in this data set, which yielded an AUC of 0.500 (95% CI 0.455-0.545).</p><p><strong>Conclusions: </strong>The EDEM model was predictive of in-hospital mortality and was superior to REMS.</p>","PeriodicalId":7105,"journal":{"name":"Academic Emergency Medicine","volume":" ","pages":"650-658"},"PeriodicalIF":3.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12173791/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kara Mesznik, Cheryl A King, Adam Horwitz, Michael Webb, Bradley J Barney, Jennifer A Hoffmann, David Brent, Jacqueline Grupp-Phelan, Lauren S Chernick
{"title":"Suicidal thoughts and behaviors among gender-minority adolescents in the emergency department.","authors":"Kara Mesznik, Cheryl A King, Adam Horwitz, Michael Webb, Bradley J Barney, Jennifer A Hoffmann, David Brent, Jacqueline Grupp-Phelan, Lauren S Chernick","doi":"10.1111/acem.15090","DOIUrl":"10.1111/acem.15090","url":null,"abstract":"<p><strong>Objective: </strong>Gender-minority youth, whose gender identity differs from their sex assigned at birth, have elevated suicide risk compared to cisgender youth, yet few studies examine their suicide risk in the emergency department (ED). Our objectives were to determine the prevalence of and assess risk and protective factors associated with prior suicide attempt (SA) and recent suicide ideation (SI) among gender-minority adolescents in the ED.</p><p><strong>Methods: </strong>We conducted a secondary analysis of gender-minority adolescents in the Emergency Department Screening for Teens at Risk for Suicide (ED-STARS) multicenter, random-series prospective cohort study. Prior SA and recent SI were based on the Columbia Suicide Severity Rating Scale and Ask Suicide-Screening Questions, respectively. We conducted Firth's logistic regressions to assess risk and protective factors associated with prior SA and recent SI.</p><p><strong>Results: </strong>Of 6641 adolescent participants in ED-STARS, 280 (4.2%) identified as gender minority. Of the gender minorities, 72% presented with a nonpsychiatric complaint, 37% admitted to a prior SA, and 25% reported recent SI. Prior SA was associated with the number of self-harm methods in the prior 12 months (adjusted odds ratio [aOR] 1.5, 95% confidence interval [CI] 1.3-1.9), sexual minority (aOR 5.0, 95% CI 2.5-10.6), and mother's history of prior SA (aOR 3.6, 95% CI 1.5-9.2). Recent SI was associated with hopelessness (aOR 4.2, 95% CI 1.5-13.9), lower positive affect (aOR 0.9, 95% CI 0.8-1.0), sexual minority (aOR 8.3, 95% CI 2.5-37.8), five or more self-harm events in the prior 12 months (aOR 4.9, 95% CI 2.1-11.6), and number of illicit drug classes (aOR 1.9, 95% CI 1.2-3.2).</p><p><strong>Conclusions: </strong>Among gender-minority ED adolescent patients, one in three experienced a SA prior to the ED visit. One in four endorsed SI within 2 weeks of the ED visit. The identified risk and protective factors among gender-minority adolescents may inform future ED-based efforts to detect and reduce suicide risk.</p>","PeriodicalId":7105,"journal":{"name":"Academic Emergency Medicine","volume":" ","pages":"619-631"},"PeriodicalIF":3.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12173796/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142997974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Matthew Johnson, Eric Segev, Alexander Bracey, Sean P Geary, Luke Duncan, Christopher Hanowitz, Denis Pauzé, Gregory P Wu
{"title":"Recovering lost opportunities in the management of critically ill patients boarding in the emergency department.","authors":"Matthew Johnson, Eric Segev, Alexander Bracey, Sean P Geary, Luke Duncan, Christopher Hanowitz, Denis Pauzé, Gregory P Wu","doi":"10.1111/acem.15077","DOIUrl":"10.1111/acem.15077","url":null,"abstract":"","PeriodicalId":7105,"journal":{"name":"Academic Emergency Medicine","volume":" ","pages":"699-701"},"PeriodicalIF":3.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142871045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Swetha Parvataneni, Michelle Haugh, Yara Sarkis, Brittany Baker, Lauren D Nephew, Marwan S Ghabril, Raj Vuppalanchi, Eric S Orman, Naga P Chalasani, Archita P Desai, Nicholas Eric Harrison
{"title":"Clinical decision instruments for predicting mortality in patients with cirrhosis seeking emergency department care.","authors":"Swetha Parvataneni, Michelle Haugh, Yara Sarkis, Brittany Baker, Lauren D Nephew, Marwan S Ghabril, Raj Vuppalanchi, Eric S Orman, Naga P Chalasani, Archita P Desai, Nicholas Eric Harrison","doi":"10.1111/acem.15088","DOIUrl":"10.1111/acem.15088","url":null,"abstract":"<p><strong>Objective: </strong>Clinical decision instruments (CDIs) could be useful to aid risk stratification and disposition of emergency department (ED) patients with cirrhosis. Our primary objective was to derive and internally validate a novel Cirrhosis Risk Instrument for Stratifying Post-Emergency department mortality (CRISPE) for the outcomes of 14- and 30-day post-ED mortality. Secondarily, we externally validated the existing Model for End-Stage Liver Disease (MELD) scores for explicit use in ED patients and prediction of the same outcomes.</p><p><strong>Methods: </strong>A cohort of 2093 adults with cirrhosis, at 16 sites in a statewide health system, was analyzed for 119 candidate variables available at ED disposition. LASSO with 10-fold cross-validation was used in variable selection for 14-day (CRISPE-14) and 30-day (CRISPE-30) logistic regression models. Area under the receiver operating characteristic curve (AUROC) was calculated for each variant of the CRISPE and MELD scores and compared via Delong's test. Predictions were compared to actual ED disposition for predictive value and reclassification statistics.</p><p><strong>Results: </strong>Median (interquartile range [IQR]) characteristics of the cohort were age 62 (53-70) years and MELD 3.0 13.0 (8.0-20.0). Mortality was 4.3% and 8.5% at 14 and 30 days, respectively. CRISPE-14 and CRISPE-30 outperformed each MELD variant, achieving AUROC of 0.824 (95% CI: 0.781-0.866) and 0.829 (0.796-0.861), respectively. MELD 3.0 AUROCs were 0.724 (0.667-0.781) and 0.715 (0.672-0.781), respectively. Compared to ED disposition, CRISPE-14, CRISPE-30, and MELD 3.0 significantly improved positive and negative predictive value and net reclassification index at multiple cutoffs. Applying CRISPE-30 (cutoff 4.5) favorably reclassified one net ED disposition for mortality for every 12 patients, while MELD 3.0 net reclassified one disposition per 84 patients.</p><p><strong>Conclusions: </strong>CDIs may be useful in risk-stratifying ED patients with cirrhosis and aiding disposition decision making. The novel CRISPE CDI showed powerful performance and requires external validation, while the existing MELD 3.0 score has moderate performance and is now externally-validated in an ED population for short-term mortality.</p>","PeriodicalId":7105,"journal":{"name":"Academic Emergency Medicine","volume":" ","pages":"604-618"},"PeriodicalIF":3.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12171671/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142942423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}