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Effect of Bongi Me’e Liquid Soap Toward Staphylococcus Epidermidis Bongi me<e:1>液皂对表皮葡萄球菌的作用
Acta Chimica Asiana Pub Date : 2019-02-15 DOI: 10.29303/aca.v2i1.9
F. Wajdi, S. Aini, F. Nardi, D. Komalasari
{"title":"Effect of Bongi Me’e Liquid Soap Toward Staphylococcus Epidermidis","authors":"F. Wajdi, S. Aini, F. Nardi, D. Komalasari","doi":"10.29303/aca.v2i1.9","DOIUrl":"https://doi.org/10.29303/aca.v2i1.9","url":null,"abstract":"Acne or commonly referred as Acne Vulgaris is a chronic skin disease due to abnormalities of sebum production in sebaceous glands caused by Staphylococcus epidermis  bacteria. Acne treatment is usually done by using antibiotics, both topical and oral like Clindamycin 1%. However, the long-term use of antibiotics might lead to resistant of  Propionibacterium acne strains or immune to Clindamycin 1%. People in Bima, particulary in Wawo district have local wisdom, that is facial using Bongi Me’e which is a traditional scrubs made of rice, tamarind, and temu giring extract that officacious as antibacterial. The purpose of this study was to determine the effectiveness of Bongi Me’e liquid soap as the antibacterial against Staphylococcus epidermis. In this research, four soap formulas were formulated and tested using well diffusion method. Formula 1 (4 ml rice extract, 3 ml temu giring extract and 2 ml tamarind extract). Formula 2 ( 2 ml rice extract, 3 ml temu giring extract and 4 ml tamarind extract). Formula 3 (2 ml rice extract, 4 ml temu giring extract, and 3 ml tamarind extract). Formula 4 (4 ml rice extract, 2 ml temu giring extract, and 3 ml tamarind extract). The inhibitory zone test indicated that the highest diameter of inhibition zone obtained in the formula 1 of 29,3 mm, followed by the formula 2 of 28 mm, formula 4 of 26,6 mm, and formula 3 that has smallest inhibitory zone by 25 mm. So, the antibacterial Bongi Me’e liquid soap was effective to inhibit acne-cause bacteria Staphylococcus epidermis","PeriodicalId":7071,"journal":{"name":"Acta Chimica Asiana","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86725366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Prediction of the Corrosion Inhibition Efficiency of Imidazole Derivatives: A Quantum Chemical Study 咪唑衍生物缓蚀效率的量子化学预测
Acta Chimica Asiana Pub Date : 2019-02-15 DOI: 10.29303/aca.v2i1.15
S. Hadisaputra, Z. Iskandar, D. Asnawati
{"title":"Prediction of the Corrosion Inhibition Efficiency of Imidazole Derivatives: A Quantum Chemical Study","authors":"S. Hadisaputra, Z. Iskandar, D. Asnawati","doi":"10.29303/aca.v2i1.15","DOIUrl":"https://doi.org/10.29303/aca.v2i1.15","url":null,"abstract":"Corrosion is a process of metal destruction due to the metal-acidic environment reaction. The uncontrolled corrosion process lead to massive losses. Administering inhibitors of organic compounds on the metal surface may prevent the corrosion processes. Organic inhibitors are low toxicity, environmentally friendly, effective easy to obtain and cheap. The study aims to determine the effect of substituents to the efficiency of corrosion inhibition of imidazole in carbon steel based on quantum chemical parameters. Corrosion inhibition efficiency values ​​are strongly influenced by the addition of substituents namely electron donors (CH3, CHCH2, NH2, CH2OH and OH) and electron withdrawal (CHO, COOH, NO2, F and Cl). The addition of amine group NH2 increased the corrosion inhibition efficiency to 91 % whereas amino group NO2 reduced the efficiency of corrosion inhibition to 64 %. Analysis of the Fukui function shows that imidazole has active sides on the C1 and C3 atoms. NBO analysis shows that there is an interaction of N5 atoms that donate electrons to Fe13 at 8.67 kcal.mol-1. In conclusion, the addition of an electron donor group increases the efficiency of corrosion inhibition of imidazole.","PeriodicalId":7071,"journal":{"name":"Acta Chimica Asiana","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87173044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Thermodynamics and Kinetics of Adoption of Ag (I) on Paramagnetic Silica Rice Husk Ash Surface 银(I)在顺磁性稻壳灰分表面吸附的热力学和动力学
Acta Chimica Asiana Pub Date : 2019-02-15 DOI: 10.29303/aca.v2i1.32
Wardian Antoni, S. Hamdiani, S. Kamali
{"title":"Thermodynamics and Kinetics of Adoption of Ag (I) on Paramagnetic Silica Rice Husk Ash Surface","authors":"Wardian Antoni, S. Hamdiani, S. Kamali","doi":"10.29303/aca.v2i1.32","DOIUrl":"https://doi.org/10.29303/aca.v2i1.32","url":null,"abstract":"Synthesis of paramagnetic silica from rice husk ash has been carried out as an adsorbent for heavy metal Ag (I). This study tried to synthesis and characterized the thermodynamics and kinetics behaviour of paramagnetic silica from the husk ash as metal adsorbent Ag (I). Determination of optimal conditions for adsorption of metal ions Ag (I) is carried out by varying the pH, concentration, and contact time of the adsorbent. The results showed that the optimum pH was at pH 3, optimal concentration Ag(I) of 350 ppm and optimal contact time of 90 minutes. At optimal conditions, paramagnetic silica adsorption capacity for metal ion Ag (I) is 323.62 mg/g. The isotherm model that is suitable for paramagnetic silica is the Freundlich isotherm model. The kinetic model that is suitable for paramagnetic silica is the Pseudo Order 2 kinetic model.","PeriodicalId":7071,"journal":{"name":"Acta Chimica Asiana","volume":"55 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75037441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Synthesis Of Mesoporiic Silica From Rice Husk Ash For Pinostrobin Based Drug Delivery 以稻壳灰为原料合成介孔二氧化硅的研究
Acta Chimica Asiana Pub Date : 2019-02-15 DOI: 10.29303/aca.v2i1.20
Rifia Wulandari, S. Hamdiani, N. Ismillayli
{"title":"Synthesis Of Mesoporiic Silica From Rice Husk Ash For Pinostrobin Based Drug Delivery","authors":"Rifia Wulandari, S. Hamdiani, N. Ismillayli","doi":"10.29303/aca.v2i1.20","DOIUrl":"https://doi.org/10.29303/aca.v2i1.20","url":null,"abstract":"A study has been conducted on the synthesis of mesoporous silica as introductory material pinostrobin anticancer compounds. The aim of this study was to synthesis paramagnetic mesoporous silica from rice husk ash waste; knowing the characteristics of silica gel and mesoporous silica from rice husk and the value of adsorption capacity (Q). Based on the results of the study, it was found that mesoporous silica can be synthesized from the rice husk ash waste. Characterization using FTIR produces silanol (Si-OH), and siloxan (Si-O-Si). The use of 30% w/w tartaric acid as a template doesn’t change the functional groups of silica. The optimum conditions of adsorption of pinostrobin compounds by mesoporous silica at the adsorption capacity of 7.049 mg/g. In simulated intestinal fluids (pH 7.4),pinostrobin is released slowly at every hour, then slightly increases at the 10th hour and continues to increase again slowly so that the pinostrobin compound is completely released at 12 hours.","PeriodicalId":7071,"journal":{"name":"Acta Chimica Asiana","volume":"28 14","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91404966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Prediction of Xanton Derivatives as Anti Heart Cancer using In Silico Quantitative Structure-Property Relationships 利用硅定量结构-性质关系预测黄酮衍生物的抗心脏肿瘤作用
Acta Chimica Asiana Pub Date : 2019-02-14 DOI: 10.29303/aca.v2i1.28
R. A. Putri, A. D. Ananto, I. Sudarma
{"title":"Prediction of Xanton Derivatives as Anti Heart Cancer using In Silico Quantitative Structure-Property Relationships","authors":"R. A. Putri, A. D. Ananto, I. Sudarma","doi":"10.29303/aca.v2i1.28","DOIUrl":"https://doi.org/10.29303/aca.v2i1.28","url":null,"abstract":"Quantitative Structure-Activity Relationship (QSAR) study have been performed on Xanthone derivatives as anti-cancer activity. The objectives of this research is to design a new Xanthone derivatives from the best  QSAR equation model. The data set were taken from the previous study, involving 41 Xanthone derivatives and their biology activities in Inhibitor Concentration 50 % (IC50). The parameters (descriptors) were calculated by semiempirical PM3 method. The selection of the best QSAR equation models was determined by multilinear regression analysis. The best linear equation resulted from that analysis is: Log 1/IC50 = 13,099 + 2,837 qC1 + 0,098 qC2 + 11,214 qC10 + 2,065 qC13 – 1,236 qC14 + 35,356 qO15 + 0,001 (vol) – 0,025 (log P) + 0,283 (dipole) n = 41; r = 0.735; adjusted r2 = 0.360; Fhit/Ftab = 1.2911; PRESS = 5.0089. Based on that model, a new Xanthon derivatives has been design which show better predicted biology activity (log 1/IC50= 15,0863), new derivatives have the log 1/IC50 higher than the old one (log 1/IC50= 9). This result indicated that new Xanthone derivatives has potential to developed as new anti-cancer drug","PeriodicalId":7071,"journal":{"name":"Acta Chimica Asiana","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74813711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis Docking Of Plasmodium Falciparum Enoyl Acyl Carrier Protein Reductase (Pfenr) With Organic Compunds From Virtual Screening Of Herbal Database 恶性疟原虫烯酰酰基载体蛋白还原酶(Pfenr)与中药数据库虚拟筛选有机化合物的对接分析
Acta Chimica Asiana Pub Date : 2018-12-14 DOI: 10.29303/aca.v3i1.14
N. D. Malau, S. F. Azzahra
{"title":"Analysis Docking Of Plasmodium Falciparum Enoyl Acyl Carrier Protein Reductase (Pfenr) With Organic Compunds From Virtual Screening Of Herbal Database","authors":"N. D. Malau, S. F. Azzahra","doi":"10.29303/aca.v3i1.14","DOIUrl":"https://doi.org/10.29303/aca.v3i1.14","url":null,"abstract":"Malaria is one of problematic infectious diseases worldwide. The absence of an effective vaccine and the spread of drug resistant strains of Plasmodium clearly indicate the necessity for the deveploment of new chemotherapeutic agents. Recent method being developed is searching a new drug of antimalarial using in silico screening, or also known as virtual screening. One of enzyme target that important for growth of the malaria parasite is Plasmodium falciparum Enoyl Acyl Carrier Protein Reductase (PfENR). Inhibition of this enzyme cause the fatty acid biosynthesis type II will be terminated. In this research, in silico screening was performed using AUTODOCK VINA software to find inhibitor candidates of PfENR by using ligands from the database of Medicinal Plants in Indonesia. On the AUTODOCK VINA software moleculer docking experiments were performed between ligands and macromolecule target PfENR. This target that has been optimized with residue removal and charges addition. Ligand is expected to be the PfENR inhibitors.","PeriodicalId":7071,"journal":{"name":"Acta Chimica Asiana","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85890626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Benzimidazole corrosion inhibition performance: A DFT Study 苯并咪唑缓蚀性能的DFT研究
Acta Chimica Asiana Pub Date : 2018-08-15 DOI: 10.29303/aca.v1i2.27
F. Wajdi, S. Hadisaputra, I. Sumarlan
{"title":"Benzimidazole corrosion inhibition performance: A DFT Study","authors":"F. Wajdi, S. Hadisaputra, I. Sumarlan","doi":"10.29303/aca.v1i2.27","DOIUrl":"https://doi.org/10.29303/aca.v1i2.27","url":null,"abstract":"The corrosion inhibition performance of benzimidazole and its derivatives have been studied by density functional theory DFT in aqueous medium. For this investigation, the corrosion inhibition efficiencies of the protonated and non-protonated spesies of benzimidazole and its derivatives were investigated. The ionization potential of the inhibitors has a strong influence on the efficiency of corrosion inhibitors. The linear correlation was shown between electronic properties and corrosion inhibition efficiency. Electron donating substituents increase the corrosion inhibition efficiency, whereas electron withdrawing substituents give the opposite effect. The NH2 substituent contributes highest, whereas NO2 provides the weakest contribution to the corrosion inhibition efficiency for both non-protonated and protonated species of inhibitors. ","PeriodicalId":7071,"journal":{"name":"Acta Chimica Asiana","volume":"201 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76000512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Protection of copper corrosion in acidic medium using pinostrobin 酸性介质中铜腐蚀的防护
Acta Chimica Asiana Pub Date : 2018-08-15 DOI: 10.29303/aca.v1i2.26
Rosita Wati, S. Hadisaputra, D. Asnawati, D. Hermanto
{"title":"Protection of copper corrosion in acidic medium using pinostrobin","authors":"Rosita Wati, S. Hadisaputra, D. Asnawati, D. Hermanto","doi":"10.29303/aca.v1i2.26","DOIUrl":"https://doi.org/10.29303/aca.v1i2.26","url":null,"abstract":"The corrosion inhibition efficiency of copper was tested by the weight loss method in 1 M H2SO4 medium in the presence of pinostrobin as inhibitor. It shows that the addition of pinostrobin inhibitor reduce the corrosion rate. The nature of thermodynamic of pinostrobin adsorption on copper surfaces follows the Freundlich isotherm. The process of inhibition is endothermic, spontaneous and physisorption. It is proved by the Ea, ΔH and ΔS and ΔG values in which the thermodynamic studies show that the values of Ea < 80 kJ.mol-1, ∆H positive, ∆S positive, and ΔG < -20 kJ.mol-1.","PeriodicalId":7071,"journal":{"name":"Acta Chimica Asiana","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77834045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
The Influence Of Relating, Experiencing, Applying, Cooperating And Transfering Learning Models Toward Chemistry Learning Outcomes 关联学习模式、体验学习模式、应用学习模式、合作学习模式和迁移学习模式对化学学习成果的影响
Acta Chimica Asiana Pub Date : 2018-08-14 DOI: 10.29303/aca.v1i2.31
Wainda Sardika Dewi, Mukhtar Harris, Jackson Siahaan
{"title":"The Influence Of Relating, Experiencing, Applying, Cooperating And Transfering Learning Models Toward Chemistry Learning Outcomes","authors":"Wainda Sardika Dewi, Mukhtar Harris, Jackson Siahaan","doi":"10.29303/aca.v1i2.31","DOIUrl":"https://doi.org/10.29303/aca.v1i2.31","url":null,"abstract":"The purpose of this study was to investigate the effect of Relating, Experiencing, Applying, Cooperating And Transfering REACT model on chemistry learning outcomes of the eleventh grade students at the senior high schools in West Lombok Indonesia. The research type is quasi-experimental design with posttest only control group design. The population in this study were all the eleventh grade students and 80 students were taken as samples. They were determined through saturated sampling techniques.  The reserach hypothesis testing was carried by the t-test. It was found that tcount 3.10 is higher that ttable (1.68) at a significant level of 5%. This result indicate that the application of the REACT learning model provides a better influence than conventional learning models on chemistry learning outcomes.","PeriodicalId":7071,"journal":{"name":"Acta Chimica Asiana","volume":"2 2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90808769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Corrosion Inhibition Efficiency Of Nicotine Based On Quantum Chemical Study 基于量子化学的尼古丁缓蚀性能研究
Acta Chimica Asiana Pub Date : 2018-08-14 DOI: 10.29303/aca.v1i2.29
Y. Wirayani, M. Ulfa, Yahmin Yahmin
{"title":"Corrosion Inhibition Efficiency Of Nicotine Based On Quantum Chemical Study","authors":"Y. Wirayani, M. Ulfa, Yahmin Yahmin","doi":"10.29303/aca.v1i2.29","DOIUrl":"https://doi.org/10.29303/aca.v1i2.29","url":null,"abstract":"The effect of substituents, electron donor groups (NH2, OH, CH2OH and CH3) and electron withdrawal groups (NO2, COOH, and Cl),  to the efficiency of corrosion inhibition of nicotine has been studied using theoretical studies. The effect of substituents toward the efficiency of corrosion inhibition of nicotine based on quantum parameters (EHOMO, ELUMO, Egap, I, χ, dan ΔN). The efficiency of corrosion inhibition based on quantum parameters is NH2 > OH > CH2OH > CH3 > BN > Cl > COOH > NO2. The addition of electron donor group NH2 has the highest inhibitory efficiency of 99.79 %. In contrast, the presence of electron withdrawal group NO2 has the opposite effect.","PeriodicalId":7071,"journal":{"name":"Acta Chimica Asiana","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82736324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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