Acta Chimica Asiana最新文献

{"title":"Environmental chemistry course assisted problem-based learning in developing students’ higher-order thinking skills and characters.","authors":"W. Wildan, S. Supriadi, Dwi Laksmiwati, R. N. Analita","doi":"10.29303/aca.v4i2.54","DOIUrl":"https://doi.org/10.29303/aca.v4i2.54","url":null,"abstract":"Character development and higher-order thinking abilities are crucial in environmental chemistry courses because they can motivate students to care about the environment. Environmental chemistry courses can benefit from a problem-based learning approach. Students learn to think critically and analytically, as well as locate and use relevant learning resources, through problem-based learning. This was a quasi-experimental study that used a pre-test post-test design. The goal of this study was to describe how problem-based learning was implemented in environmental chemistry classes and how it influenced the development of higher-order thinking abilities and student personalities. Data was gathered through an essay test that required higher-order thinking skills, and students' personalities were determined through an inventory. ANOVA statistics were used to evaluate the data. The stages of concept presentation, presentation of factual problems in various forms, group discussions, and class discussions were used to implement problem-based learning in the Environmental Chemistry course; (2) problem-based learning can significantly improve students' higher-order thinking skills and characters; and (3) high-order thinking skills contribute significantly to character development.\u0000 ","PeriodicalId":7071,"journal":{"name":"Acta Chimica Asiana","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83595505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physical Characteristics, Total Phenolic, and Flavonoid Content of Coccinia grandis (L.) Voigt Leaves Extract","authors":"I. Putra, I. Kusumawati, N. L. U. Sumadewi","doi":"10.29303/aca.v4i2.66","DOIUrl":"https://doi.org/10.29303/aca.v4i2.66","url":null,"abstract":"Coccinia grandis (L.) Voigt is an herbal plant that has been widely used for the treatment of various types of diseases. The phenolic and flavonoid content of plant extracts largely determine their pharmacological activity. The aim of this study was to determine the total phenolic and flavonoid contents of the ethanol extract of C. grandis leaves. Leaf samples in this study were obtained in the area of ​​Dalung, North Kuta, Badung, Bali. The powdered C. grandis leaf was extracted by maceration method using 70% ethanol followed by evaporation using an oven at 45oC to obtain a thick extract. The non-specific parameters of the extract were then determined, such as moisture content, ash content, and acid insoluble ash. Total phenolic content was determined using the follin-ciocalteu method and total flavonoid content was determined using the aluminum chloride method. Based on the research results, the yield of C. grandis leaf extract was 19.36%. C. grandis leaf extract has a description of a thick and sticky extract, blackish brown color, distinctive aroma, and a bitter sour taste. The water content of the ethanolic extract of C. grandis leaves was 9.93±0.03% (g/g). The total ash value of the simplicia and ethanolic extract of C. grandis leaves were 20.76±0.15% (g/g) and 27.38±0.19% (g/g), respectively. The acid insoluble ash content of the extract was 4.05±0.30% (g/g). The total phenolic and total flavonoid contents of the extract were 111.92±0.49 µg GAE/mg dry extract and 73.60±3.53 µg QE/mg dry extract, respectively.","PeriodicalId":7071,"journal":{"name":"Acta Chimica Asiana","volume":"77 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78088019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Stirring Speeds to the Entrapment Efficiency in a Nanoparticles Formulation of Java Plum’s seed Ethanol Extract (Syzygium cumini)","authors":"Widayanti Supraba, Yohanes Juliantoni, A. D. Ananto","doi":"10.29303/ACA.V4I1.50","DOIUrl":"https://doi.org/10.29303/ACA.V4I1.50","url":null,"abstract":"Java Plum’s (Syzygium cumini) seed contains flavonoids in the form of quercetin. Quercetin plays an essential role in stimulating insulin production from pancreatic beta cells. However, it could be easily degraded by gastric acid or the digestive system. Thus, in this research, a good delivery system for quercetin will be established, namely nanoparticles. The study objectives are determining the entrapment efficiency’s percentage of nanoparticle preparations from ethanol extracts of Java Plum’s seeds as well as observing the effect of stirring speed on the percentage of entrapment efficiency. Java Plum’s seed extract was obtained by maceration method using ethanol 70% with the ratio between the simplicial powder and solvent is 1 : 4 respectively. Meanwhile, the solvent evaporation process was undergone by using a water bath with temperature not exceeding 70°C. The nanoparticle formulation of Java Plum’s seed extract was made by adding polymers in the form of chitosan and sodium tripolyphosphate cross-linker with three variations of stirring speed (500, 1000, and 1500 rpm) using a magnetic stirrer. The percentage of entrapment efficiency was obtained by subtracting the flavonoids levels of Java Plum’s seeds extract and flavonoids levels of Java Plum’s seeds extract in nanoparticles. Then, the value was divided by flavonoids levels of Java Plum’s seeds extract and multiplied by 100%. Quercetin levels obtained by absorbance readings using spectrophotometry UV-Visible, then absorbance value added into variable X on equation quercetin’s standard curve y = 0,0229x + 0,0644. The results show that the percentage of entrapment efficiency at speed variations of 500, 1000, and 1500 rpm are 48.8459%, 49.1064%, and 56.0413% respectively. According to the t-test two independent samples statistical test, the data has a 0.961 probability value (500 rpm vs 1000 rpm), 0.324 probability value (1000 rpm vs 1500 rpm), 0.25 (500 rpm vs 1500 rpm). Probability value > 0.05, which means the stirring speed does not significantly influence the percentage of entrapment efficiency. \u0000 ","PeriodicalId":7071,"journal":{"name":"Acta Chimica Asiana","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90649259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis of 5-nitrovanillin in low temperature as cyanide anion sensor","authors":"R. Rahmawati, Syarifa Wahidah Al Idrus, S. Supriadi, Lalu Sulman","doi":"10.29303/ACA.V4I1.46","DOIUrl":"https://doi.org/10.29303/ACA.V4I1.46","url":null,"abstract":"In the synthesis of the organic sensor, the molecular structure will affect the ability of a compound to be used as a colorimetric chemosensor. Here, we present a simple synthesis technique for 5-nitrovanillin. It has been successfully synthesized using nitric acid as a source of nitro groups. Dichloromethane DCM was used as a solvent, and the synthesis was carried out at low temperatures (under 5°C). The method produces a good yield. The nitro group attached to the structure of the chemosensor plays a role in prolonging the electron delocalization. Its effect is in the process of anion recognition by the chemosensor. The formation of a sensor-analyte complex between the chemosensor and anion produces a color change in the solution.","PeriodicalId":7071,"journal":{"name":"Acta Chimica Asiana","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88835569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Indonesian Modified Clay for Dye Waste Treatment","authors":"I. Sumarlan, I. Fatimah, K. Wijaya","doi":"10.29303/aca.v3i1.11","DOIUrl":"https://doi.org/10.29303/aca.v3i1.11","url":null,"abstract":"Synthesis and Characterization of TiO2 Coated on Clay Pillared Alumina (PILC) for Methyl Orange Photodegradation Under UV Illumination. The synthesis included both pillarization the clay with alumina and TiO2 coated on PILC using impregnation method. Some characterizations also were employed to this research such as X-Ray Diffraction (XRD), Scanning Electron Microscopy (SEM), N2 Adsorption Isotherm and UV-Visible Diffuse Reflectance (DR UV). The photocatalyst was then used to decompose waste dye, methyl orange (MO). Among three photocatalysts that were successfully synthesized, PILC Ti 1.0% had the highest activity to decompose the waste dye.","PeriodicalId":7071,"journal":{"name":"Acta Chimica Asiana","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76003401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis of Biodegradable Superabsorbent Polymers from Carboxymethyl Cellulose/Humic Acid","authors":"N. Ismillayli, S. Kamali, S. Hadi, D. Hermanto","doi":"10.29303/aca.v2i2.8","DOIUrl":"https://doi.org/10.29303/aca.v2i2.8","url":null,"abstract":"Superabsorbent polymer (SAP) blend has been synthesized from carboxymethyl cellulose (CMC), humic acid, and aluminum sulphate octadecahydrate cross-linker.  SAP is hydrophilic networks that can absorb and retain huge amount of water within their structures. Humic acid as starting material of polymer, was isolated from subgrade Batujai Dam by using IHSS method. Water Absorption Capacity (WAC) measurement, FTIR analysis, and agitation tests to investigate the cross-linking process and which of Al3+ and SO42-  ions causes the crosslinking are carried out. Optimum cross-linking ratio of CMC and cross-linker appeared to be 2wt% corresponded to WAC determination. FTIR spectrum of CMC/humic acid blend and agitation test showed that CMC react with humic acid during polymerization process via Al3+ ion. \u0000  \u0000Keywords: carboxymethyl cellulose; Al3+ ion; humic acid; superabsorbent polymer.","PeriodicalId":7071,"journal":{"name":"Acta Chimica Asiana","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82399567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"QSAR treatment of meisoindigo derivatives as a potentbreast anticancer agent","authors":"E. Lestari, A. D. Ananto, Maulida Septiyana, S. Hadisaputra","doi":"10.29303/aca.v2i2.12","DOIUrl":"https://doi.org/10.29303/aca.v2i2.12","url":null,"abstract":"A quantitative structure-activity relationship (QSAR) analysis of meisoindigo derivatives as a breast anticancer has been carried out. This study aimed to obtain the best QSAR model in order to design new meisoindigo based compounds with best anticancer activity. The semiempirical PM3 method was used for descriptor calculation. The best QSAR model was built using multilinear regression (MLR) with enter method. It was found that there were 19 new meisoindigo derivativeswith better predictive a potent anticancer agent. The best compound was (E)-2-(1-((3-ethylisoxazol-5-yl)methyl)-2-oxoindolin-3-ylidene)-N-(4-methoxyphenyl)acetamide with the value of IC505.31144 x10-15 (μM).","PeriodicalId":7071,"journal":{"name":"Acta Chimica Asiana","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72762026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chemical Constituents of Buah Makasar [Brucea Javanica (L) Merr] Leaves and Seed Extract","authors":"H. Muliasari, Candra D Hamdin, A. D. Ananto, M. Ihsan","doi":"10.29303/aca.v2i2.10","DOIUrl":"https://doi.org/10.29303/aca.v2i2.10","url":null,"abstract":"Buah Makasar [Brucea javanica (L) Merr] is one of the local plants in Lombok Island that is traditionally used for diabetic medication. The purpose of this research was to identify the chemical constituents containing in methanol leaves and seed extract of Buah Makasar. The methods used were phytochemical screening for some groups of chemical compounds and GC-MS analysis. The result of phytochemical screening showed that methanol extract of B. javanica seed contains alkaloids, terpenoids, and tannin with a high intensity; while the leaves extract contains alkaloids, flavonoids, steroids, tannin, and saponin. The differences of chemical compositions in the leaves and seed extract may give them have different bioactivities. GC-MS analysis showed some fatty acids containing in the seed extract such as stearic acid and palmitic acid.","PeriodicalId":7071,"journal":{"name":"Acta Chimica Asiana","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91431829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis of Rice Husk Mesoporous Silica as pH Responsive Release Material","authors":"Pidia Aulia, S. Hamdiani, I. Sumarlan","doi":"10.29303/aca.v2i2.21","DOIUrl":"https://doi.org/10.29303/aca.v2i2.21","url":null,"abstract":"The synthesis of mesoporous silica as a delivery agent for the ethyl para-methoxycinnamate has been carried out. The study aims to determine the process of mesoporous silica synthesis from sodium silicate from the smelting of rice husk ash, determine the adsorption capacity of mesoporous silica in the ethyl para-methoxycinnamate and the pH responsive release of ethyl para-methoxycinnamate with mesoporous silica as a delivery agent in simulated intestinal and gastric fluids. It was found that mesoporous silica can be synthesized from rice husk ash with a 30% tartaric acid template. Characterization of mesoporous silica using FTIR spectroscopy showed the presence of silanol (Si-OH) and siloxane (Si-O-Si) functional groups. Mesoporous silica from rice husk ash is able as adsorbent for the ethyl para-methoxycinnamate with the adsorption capacity of 8.26 mg/g. The release test of gastric simulation fluid (pH 1.2) showed that the ethyl-para-methoxycinnamate was released from silica for a period of 12 hours. In the intestinal simulation fluid (pH 7.4), the release of the ethyl para-methoxycinnamate occurred slowly at the first hour, then gradually increased at 5 hour up to 12 hour.","PeriodicalId":7071,"journal":{"name":"Acta Chimica Asiana","volume":"16 42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79988726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Naked-Eye Fluoride Ion Recognition Based Vanilin Derivative Chemosensors","authors":"R. Rahmawati, B. Purwono, S. Matsjeh","doi":"10.29303/aca.v2i2.16","DOIUrl":"https://doi.org/10.29303/aca.v2i2.16","url":null,"abstract":"Two new receptors S2 and S6 were designed and synthesized based on benzimidazole and azo-benzimidazole synthesized from vanillin for the colorimetric detection of fluoride ion. The presence of nitro group in S2 and azo in S6 makes –OH  proton (binding site) acidic and therefore it could deprotonate with addition of basic anion such as fluoride. Hydroxyl (–OH) functionality which detects basic fluoride ions via hydrogen-bonding mechanism wich is mechanism involved in the color change of receptor R2 and R6, its mean that initial hydrogen bond formation of F− ion with –OH group.","PeriodicalId":7071,"journal":{"name":"Acta Chimica Asiana","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86959290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}