Acta medica Iugoslavica最新文献

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Levamisole treatment of oligospermia. 左旋咪唑治疗少精子症。
Acta medica Iugoslavica Pub Date : 1990-01-01
M I Würzburger, G M Prelević, S D Brkić, S Vucković, N Despotović, V Milović
{"title":"Levamisole treatment of oligospermia.","authors":"M I Würzburger,&nbsp;G M Prelević,&nbsp;S D Brkić,&nbsp;S Vucković,&nbsp;N Despotović,&nbsp;V Milović","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>On the basis of elevated levels of seminal plasma immunoglobulins and a decreased production of LMI in the presence of PPD, 6 patients (out of the idiopathic normogonadotrophic oligospermic group) were selected for a therapeutic trial with levamisole. The following regime of treatment was applied: 3 days on levamisole (150 mg per day) followed by a 10 day interval without treatment, for a period of three months. The sperm count increased in 5 out of 6 patients and motility increased in 2. At the same time a reduction in seminal plasma IgG levels was observed in all treated patients. A significant increase of EA rosettes was observed after treatment.</p>","PeriodicalId":7058,"journal":{"name":"Acta medica Iugoslavica","volume":"44 4","pages":"357-65"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13246698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Amino acid supplemented diet vs. selective low protein diet in chronic renal failure. 氨基酸补充饮食与选择性低蛋白饮食对慢性肾衰竭的影响。
Acta medica Iugoslavica Pub Date : 1990-01-01
D Vujić, L Djukanović
{"title":"Amino acid supplemented diet vs. selective low protein diet in chronic renal failure.","authors":"D Vujić,&nbsp;L Djukanović","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Two groups of patients with chronic renal failure (creatinine clearance 13 ml/min) were treated with two different low protein diets: unselected protein diet with 0.35 g of protein/kg/day supplemented with amino acids (first group; 10 patients) and selective protein restricted diet with 0.6 g/kg/day of high biologically valuable proteins (second group; 9 patients). Both diets showed a good patient compliance. The serum urea level decreased significantly only in the first group of patients with a simultaneous disappearance of uremic gastrointestinal side effects. Progression of renal failure, shown by plotting the reciprocal of the serum creatinine concentration against the time, was significantly slower in the first group of patients and therefore their survival without dialysis was longer than that in the second group. The nutritional state was well maintained in both groups. Comparison of two low protein diets showed that the unselected protein diet supplemented with amino acids is more effective in delaying the progression of renal failure. The clinical state of patients is improved and their protein nutrition maintained.</p>","PeriodicalId":7058,"journal":{"name":"Acta medica Iugoslavica","volume":"44 4","pages":"377-87"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13247297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The value of systematic monitoring of oxygen consumption in the diagnosis and therapy of septic shock]. [系统监测耗氧量在脓毒性休克诊治中的价值]。
Acta medica Iugoslavica Pub Date : 1990-01-01
V Pilas, M Cubrilo, V Bakula, S Vranjkovic, B Bakula, A Bilic
{"title":"[The value of systematic monitoring of oxygen consumption in the diagnosis and therapy of septic shock].","authors":"V Pilas,&nbsp;M Cubrilo,&nbsp;V Bakula,&nbsp;S Vranjkovic,&nbsp;B Bakula,&nbsp;A Bilic","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In 31 patients with sepsis and multiple organic dysfunction, changes in the systemic oxygen consumption (VO2) during reanimation were observed in order to discover more objective indicators of the course and prognosis of the disease. In a prospective randomized study, 21 live (Group 1) and 11 dead patients (Group 2) were included. The investigation was based upon the application of the invasive tracing of oxygen hemodynamics and transport. The findings of the initially hypovolemic status were compared with those of the stabile normovolemic status obtained by the application of infusions and the blood volume substitute. In the early phase of the disease there were no significant differences in the clinical finding of the circulatory shock and the volume deficit of the circulated blood between these two groups of patients. Group 1 patients had lower values of the cardiac index (CI) and the systemic oxygen transport (DO2). In them there was a greater frequency of acute organic insufficiency, especially pulmonal, renal and hepatal. In the initial status VO2 decreased. In the normovolemic status of Group 1, a significant VO2 was found, while in Group 2 in spite of a DO2 increase and hemodynamics improvement, a more significant VO2 increase was not obtained. As VO2 is an objective indicator of oxidative metabolic reactions of the organism and the circulatory system, the authors maintain that by the VO2 tracing, a better insight into the seriousness and course of the disease is obtained, and that an inadequate VO2 finding during the therapeutic treatment requires a revision of the treatment.</p>","PeriodicalId":7058,"journal":{"name":"Acta medica Iugoslavica","volume":"44 5","pages":"489-98"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13232616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Screening of newborns for congenital hypothyroidism in Croatia--organization and first results. 克罗地亚新生儿先天性甲状腺功能减退症筛查——组织和初步结果
Acta medica Iugoslavica Pub Date : 1990-01-01
V Sarnavka, D Mardesić, G Gjurić, M Vlatković, M Dumić, D Milicić, J Popović
{"title":"Screening of newborns for congenital hypothyroidism in Croatia--organization and first results.","authors":"V Sarnavka,&nbsp;D Mardesić,&nbsp;G Gjurić,&nbsp;M Vlatković,&nbsp;M Dumić,&nbsp;D Milicić,&nbsp;J Popović","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In 1985 a newborn screening programme for the detection of congenital hypothyreosis was introduced in Croatia in addition to the already existing one for phenylketonuria. The paper delineates the organization of the screening programme, the method used, and the first results. Clinical manifestations, somatic and mental development, as well as laboratory findings of the first eleven children with congenial hypothyroidism detected by the screening programme and followed-up regularly are presented in more detail.</p>","PeriodicalId":7058,"journal":{"name":"Acta medica Iugoslavica","volume":"44 1","pages":"3-14"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13487115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Intensive radiotherapy and polychemotherapy, clinical stage and systemic manifestations of the disease as parameters important in the prognosis for Hodgkin's disease]. 【何杰金氏病的强化放疗和多化疗、临床分期和全身性表现是影响预后的重要参数】。
Acta medica Iugoslavica Pub Date : 1990-01-01
J Maras, M Dubravcić, M Konstantinović, N Stula
{"title":"[Intensive radiotherapy and polychemotherapy, clinical stage and systemic manifestations of the disease as parameters important in the prognosis for Hodgkin's disease].","authors":"J Maras,&nbsp;M Dubravcić,&nbsp;M Konstantinović,&nbsp;N Stula","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the period from 1961 to 1982, 82 patients (36 females and 46 males) with Hodgkin's disease were treated. The median age was 40 years. According to the way of treatment, the patients were divided into two groups, the first group with 30 patients treated by local x-rays and/or monochemotherapy (treated up to 1971) and the second group with 52 patients treated by aggressive tele-cobalt therapy and/or MOPP polychemotherapy (after 1972). In the first group of patients, complete remission was achieved in 9 cases, partial remission in 15, while there was no remission in 6 cases. In the second group, complete remission was achieved in 40 cases, partial remission in 9, while no remission could be achieved in 3 cases. The difference in the number of remissions achieved between the patients treated up to 1971 and patients treated later is statistically significant (chi 2 = 15.52 p less than 0.0001). The median age was significantly higher in the group of patients treated by aggressive therapy (65:12 months). Seven patients from the first group survived for more than 5 years, 5 being still alive. In the second groups 29 patients survived for more than 5 years, 24 of them being still alive. The difference in survival between these two groups is significant (chi 2 = 11.37; p less than 0.001). There is a significant difference in surviving between patients in different stages of the disease (chi 2 = 27.47; p less than 0.00001). Between the patients without general symptoms (A) and the patients with systemic manifestations (B) the difference in numbers of remissions is statistically significant (chi 2 = 8.44; p less than 0.005). The difference in survival between these two groups of patients is also significant (chi 2 = 16.52; p less than 0.0001).</p>","PeriodicalId":7058,"journal":{"name":"Acta medica Iugoslavica","volume":"44 1","pages":"35-46"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13487116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Narcissistic depression in schizophrenia]. [精神分裂症中的自恋抑郁症]。
Acta medica Iugoslavica Pub Date : 1990-01-01
M Trbović
{"title":"[Narcissistic depression in schizophrenia].","authors":"M Trbović","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In individual analytically oriented psychotherapy as a research method, observing a random sample of 34 schizophrenics with the symptoms of depressive syndrome, the author has found that depression in schizophrenia is determined by narcissistic injuries, by a collapse of narcissistic satisfactions through the loss of \"ego\" functions, completeness, competitiveness, and competence. The depressive model is most frequently encountered in florid schizophrenic psychosis, at the beginning of hospitalization, but depending on the intensity and depth of narcissistic traumas and losses, it can develop also in any phase of the therapeutic process and the course of illness. In the author's view, the depressive model in schizophrenia is not conditioned by the neuroleptic treatment. Its recognition is very important for the therapy of suicidal tendencies, and for their prevention in particular.</p>","PeriodicalId":7058,"journal":{"name":"Acta medica Iugoslavica","volume":"44 1","pages":"59-64"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13487119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The effect of thyroxine on renal function in experimental acute renal insufficiency]. 甲状腺素对实验性急性肾功能不全患者肾功能的影响。
Acta medica Iugoslavica Pub Date : 1990-01-01
S Ilić, M Bogićević, V Savić, P Vlahović, V Stefanović
{"title":"[The effect of thyroxine on renal function in experimental acute renal insufficiency].","authors":"S Ilić,&nbsp;M Bogićević,&nbsp;V Savić,&nbsp;P Vlahović,&nbsp;V Stefanović","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The aim of the study was to investigate the influence of exogenous thyroxine upon the kidney function in the experimental renal failure induced by the uranyl acetate application. Acute renal failure was induced by uranyl acetate in 32 rats, divided into 4 groups, each consisted of 8 rats. The group of untreated animals and the group of animals treated with thyroxine only were used as controls. Then glomerular filtration rate was determined in all the rats taken in the experiment. The comparison was made between the control or the group with acute renal failure without the thyroxine treatment and the groups treated with a single application of thyroxine before, simultaneously and after the uranyl acetate injection. An improvement of the glomerural filtration rate and a decrease of the blood nitrogen retention were obtained in rats with acute renal failure pretreated with thyroxine. Necrotic alterations of the kidney cortex were less marked in this group than in the group without thyroxine treatment. The improvements of the kidney function and morphology in acute renal failure suggest the possibility of the protective effect of thyroxine.</p>","PeriodicalId":7058,"journal":{"name":"Acta medica Iugoslavica","volume":"44 2","pages":"105-16"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13502800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Use of recombinant erythropoietin on secondary anemia in patients in the terminal phase of renal insufficiency on hemodialysis]. [重组红细胞生成素在血液透析肾功能不全终末期继发性贫血中的应用]。
Acta medica Iugoslavica Pub Date : 1990-01-01
V Gasparović, Z Puretić, B Vrhovac, M Gjurasin, D Puljević
{"title":"[Use of recombinant erythropoietin on secondary anemia in patients in the terminal phase of renal insufficiency on hemodialysis].","authors":"V Gasparović,&nbsp;Z Puretić,&nbsp;B Vrhovac,&nbsp;M Gjurasin,&nbsp;D Puljević","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A group of 6 patients with a history of end-stage renal insufficiency on hemodialysis was receiving erythropoietin (EPO) in a dosage of 50 IU/kg body weight i. v. The hemogram values were followed regularly every week and the patients underwent other laboratory evaluations every month. At the beginning of the study, the number of erythrocytes amounted to 2.2 +/- 0.3 x 10(12)/l. After 4 weeks it was 2.3 +/- 0.4 (NS) (p = 0.001), after 8 weeks 2.8 +/- 0.4 (p = 0.007), and after 12 weeks 3.2 +/- 0.3. At the beginning, hemoglobin was 70 +/- 8 g/l, after 4 weeks 76.3 +/- 13.7 (NS), after 8 weeks 95.7 +/- 14.3 (p = 0.008), and after 12 weeks 102.2 +/- 12 (p = 0.001). The hematocrit value rose from 21.4 +/- 3.4 at the beginning of the study to 32.1 +/- 3.6 (p = 0.001) after 12 weeks. The trial showed no significant effect of EPO on serum potassium which amounted to 5.3 +/- 0.4 mmol/l at the beginning of the trial and 5.6 +/- 0.8 (NS) after 12 weeks; the rate of the rise of platelets from 132.8 +/- 2.4 x 10(9)/l to 155.2 +/- 42.2 was not significant either. The results demonstrate a marked improvement in the red blood cells of patients receiving EPO in the end-stage of renal insufficiency and its influence on their general condition. One female patient was excluded from the study participation because of a severe bone pain.</p>","PeriodicalId":7058,"journal":{"name":"Acta medica Iugoslavica","volume":"44 2","pages":"129-35"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13502801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primary prevention of perinatal impairments in the newborn. 新生儿围产期损害的初级预防。
Acta medica Iugoslavica Pub Date : 1990-01-01
J Grujić, Z Petković, M Stojcević-Polovina, M Visnar-Klobucar, D Vignjević
{"title":"Primary prevention of perinatal impairments in the newborn.","authors":"J Grujić,&nbsp;Z Petković,&nbsp;M Stojcević-Polovina,&nbsp;M Visnar-Klobucar,&nbsp;D Vignjević","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effects of intrauterine hypoxia on the motorial development of forty infants was studied by synthesizing the findings obtained by a team of obstetricians, neonatologists and physiatrists. The pH of the blood of the examinees was measured during delivery to detect hypoxia. Analyses of the results obtained have shown that the degree of deviation from a normal neurophysiological development is directly proportional to the degree of hypoxia. The findings indicate the importance of the early detection of intrauterine hypoxia.</p>","PeriodicalId":7058,"journal":{"name":"Acta medica Iugoslavica","volume":"44 3","pages":"243-6"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13546092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Spontaneous bacterial peritonitis in patients with decompensated liver cirrhosis and "tense" ascites]. 【失代偿性肝硬化伴“紧张性”腹水患者的自发性细菌性腹膜炎】。
Acta medica Iugoslavica Pub Date : 1990-01-01
I Rotkvić, P Sikirić, J Jukić, S Krizanac, V Zjacić-Rotkvić, T Anić, M Duvnjak, S Mise, S Knezević
{"title":"[Spontaneous bacterial peritonitis in patients with decompensated liver cirrhosis and \"tense\" ascites].","authors":"I Rotkvić,&nbsp;P Sikirić,&nbsp;J Jukić,&nbsp;S Krizanac,&nbsp;V Zjacić-Rotkvić,&nbsp;T Anić,&nbsp;M Duvnjak,&nbsp;S Mise,&nbsp;S Knezević","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the study 52 patients with decompensated liver cirrhosis and \"tense\" ascites were included. According to the clinical picture, ascites cultures and the number of polymorphonuclears in cmm of the ascitic fluid, all patients were selected in one of the following groups: 1. group of patients with sterile ascites (28), 2. group of patients with spontaneous peritonitis (16), and 3. group of patients with bacterascites (8). The results have shown that the incidence of spontaneous peritonitis is much higher in the group of \"tense\" ascites patients than in the group of all patients with ascites, the ratio being 30.7% compared to 6% in all cirrhotic patients with ascites. Spontaneous bacterial peritonitis correlates with increased polymorphonuclears in the ascitic fluid (p less than 0.05), decreased pH values (p less than 0.0), and increased amounts of total proteins in the ascitic fluid (p less than 0.05). The lethality rate in the group of spontaneous peritonitis and sterile ascites was 43.7% and 7.1% respectively. Early diagnosis and, of course, adequate therapy are the main points in spontaneous bacterial peritonitis.</p>","PeriodicalId":7058,"journal":{"name":"Acta medica Iugoslavica","volume":"44 4","pages":"285-95"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13246693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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