Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology最新文献_第8页

Further studies on the growth inhibition of Streptococcus mutans OMZ 176 by xylitol. 木糖醇对变形链球菌omz176生长抑制作用的进一步研究。

Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology Pub Date : 1986-04-01 DOI: 10.1111/j.1699-0463.1986.tb03026.x

S Assev, G Rölla

{"title":"Further studies on the growth inhibition of Streptococcus mutans OMZ 176 by xylitol.","authors":"S Assev, G Rölla","doi":"10.1111/j.1699-0463.1986.tb03026.x","DOIUrl":"https://doi.org/10.1111/j.1699-0463.1986.tb03026.x","url":null,"abstract":"Thin-layer chromatography (TLC) of extracts of cells which had been exposed to 14C-xylitol indicated that xylulose-phosphate is produced by the cells in addition to the previously reported xylitol-phosphate. Resting cell cultures of Streptococcus mutans OMZ 176 pretreated with xylitol were exposed to 14C-glucose and glycolytic metabolites identified by TLC of boiling water extracts of the cells. The developed TLC-sheets showed an accumulation of 14C-hexose-6-phosphates in the xylitol-treated bacteria. This could indicate that a xylitol metabolite, or metabolites, compete with fructose-6-phosphate for the phosphofructokinase, since the glycolysis is inhibited at this step. It was also shown that after accumulation of xylitol-5-phosphate, the bacteria were able to expel xylitol, presumably after and intracellular dephosphorylation of xylitol-5-phosphate; a \"futile cycle\" is thus present in these cells. Xylitol is taken up and phosphorylated, and at a later step dephosphorylated and expelled. The most important inhibition mechanism was judged to be the competitive inhibition of the glycolysis at the fructose-6-phosphate level.","PeriodicalId":7045,"journal":{"name":"Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology","volume":"94 2","pages":"97-102"},"PeriodicalIF":0.0,"publicationDate":"1986-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1699-0463.1986.tb03026.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14846746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 46

Pseudomonas aeruginosa virulence factors: modifications by sub-inhibitory concentrations of carbenicillin or gentamicin. 铜绿假单胞菌毒力因子:卡比西林或庆大霉素亚抑制浓度的改变。

Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology Pub Date : 1986-04-01 DOI: 10.1111/j.1699-0463.1986.tb03021.x

A R Ogaard, K Bjøro, G Bukholm, B P Berdal

引用次数: 11

Evaluation of Minibact, a new system for rapid identification of Enterobacteriaceae. Comparison of Minibact, Micro-ID and API 20E with a conventional method as reference. 快速鉴定肠杆菌科新系统minibacact的评价。Minibact、Micro-ID和API 20E与常规方法的比较。

Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology Pub Date : 1986-04-01

P Kjaeldgaard, B Nissen, N Lange, H Laursen

引用次数: 0

Morphological study of the in vitro cytotoxic effect of alpha-hemolytic E. coli bacteria and culture supernatants on human blood granulocytes and monocytes. 溶血大肠杆菌和培养上清对人血液粒细胞和单核细胞体外细胞毒作用的形态学研究。

Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology Pub Date : 1986-04-01 DOI: 10.1111/j.1699-0463.1986.tb03023.x

O V Gadeberg, J Blom

{"title":"Morphological study of the in vitro cytotoxic effect of alpha-hemolytic E. coli bacteria and culture supernatants on human blood granulocytes and monocytes.","authors":"O V Gadeberg, J Blom","doi":"10.1111/j.1699-0463.1986.tb03023.x","DOIUrl":"https://doi.org/10.1111/j.1699-0463.1986.tb03023.x","url":null,"abstract":"The morphological changes of human blood granulocytes and monocytes caused in vitro by alpha-hemolytic strains of E. coli and bacteria-free culture supernatants of these bacteria were studied by light- and transmission electron microscopy. The following sequence of cellular alterations were observed: Cessation of intracellular cytoplasmic streaming and cellular movements succeeded by extension of cytoplasmic pseudopodia, degranulation and development of cytoplasmic and nuclear edema. Within two hours the leukocytes appeared as empty sacks. Finally, long straight filaments were formed between the cells. The changes induced by alpha-hemolytic bacteria and culture supernatants containing free alpha-hemolysin appeared to be identical. The cytotoxic effect became more pronounced as the numbers of bacteria, the hemolytic activity of growth supernatants or the period of incubation were increased. A beta-hemolytic and a nonhemolytic E. coli strain were not cytotoxic.","PeriodicalId":7045,"journal":{"name":"Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology","volume":"94 2","pages":"75-83"},"PeriodicalIF":0.0,"publicationDate":"1986-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1699-0463.1986.tb03023.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14645970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Coumermycin: in vitro activity against 251 clinical isolates of bacteria compared with the activities of eight other antibacterial agents. 与其他8种抗菌剂的体外抑菌活性进行比较。

Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology Pub Date : 1986-04-01 DOI: 10.1111/j.1699-0463.1986.tb03024.x

A Digranes, A Salveson, W L Dibb

{"title":"Coumermycin: in vitro activity against 251 clinical isolates of bacteria compared with the activities of eight other antibacterial agents.","authors":"A Digranes, A Salveson, W L Dibb","doi":"10.1111/j.1699-0463.1986.tb03024.x","DOIUrl":"https://doi.org/10.1111/j.1699-0463.1986.tb03024.x","url":null,"abstract":"The in vitro activity of coumermycin has been compared with those of ampicillin, clindamycin, cloxacillin, doxycycline, erythromycin, netilmicin, penicillin G and vancomycin. A total of 251 clinical isolates of Gram-positive cocci were examined. The minimal inhibitory concentration (MIC) was determined by an agar dilution method. Clindamycin, coumermycin and erythromycin were the most active drugs against Staphylococcus aureus and S. epidermidis on a weight-for-weight basis. All the staphylococcal isolates were inhibited by coumermycin at a concentration of 0.12 mg/l or less. Netilmicin seemed to be somewhat more active against S. epidermidis than against S. aureus. The MICs of vancomycin for the staphylococcal isolates were clustered around 1 mg/l. Streptococcus pneumoniae, S. pyogenes and S. agalactiae were highly susceptible to penicillin G and erythromycin; most isolates were inhibited by 0.03 mg/l or less of either drug. Coumermycin showed poor activity against S. pyogenes, S. agalactiae and enterococci. Most of the S. pneumoniae isolates had also high MICs, although a wide range of sensitivities was found.","PeriodicalId":7045,"journal":{"name":"Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology","volume":"94 2","pages":"85-8"},"PeriodicalIF":0.0,"publicationDate":"1986-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1699-0463.1986.tb03024.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14846744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The antibiotic effect of the anti-depressive drug femoxetine and its stereo-isomeric analogs on diarrhoea producing enterobacteriaceae. 抗抑郁药物非莫西汀及其立体异构体类似物对腹泻肠杆菌科的抗生素作用。

Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology Pub Date : 1986-04-01

J E Kristiansen, I Mortensen, K Gaarslev

引用次数: 0

The pneumococcus and the mouse protection test: inoculum, dosage and timing. 肺炎球菌及小鼠保护试验:接种量、剂量及时间。

Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology Pub Date : 1986-02-01 DOI: 10.1111/j.1699-0463.1986.tb03017.x

N Frimodt-Møller, V F Thomsen

引用次数: 17

Influence of a carcinogenic agent, 7.12 dimethylbenz (alpha) anthracene (DMBA), on production of interferon alpha/beta in murine and human cells. 致癌物7.12二甲基苯(α)蒽(DMBA)对小鼠和人类细胞中α / β干扰素产生的影响

Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology Pub Date : 1986-02-01 DOI: 10.1111/j.1699-0463.1986.tb03019.x

M Degré, M Holberg-Petersen

引用次数: 3

The microscopic diagnosis of Pneumocystis carinii. An evaluation of the gram, the methylene blue, and the Ziehl-Neelsen procedures. 卡氏肺囊虫的显微诊断。克，亚甲基蓝，和齐尔-尼尔森程序的评估。

Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology Pub Date : 1986-02-01

P B Nielsen, P Goyot, M Mojon

引用次数: 0

Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology Pub Date : 1986-02-01 DOI: 10.1111/j.1699-0463.1986.tb03016.x

M H Persson, C Schalén, B Berggård, L Lögdberg, L Björck

{"title":"Related bindings of aggregated beta 2-microglobulin, IgG Fab, kappa and lambda light chains to group A streptococci.","authors":"M H Persson, C Schalén, B Berggård, L Lögdberg, L Björck","doi":"10.1111/j.1699-0463.1986.tb03016.x","DOIUrl":"https://doi.org/10.1111/j.1699-0463.1986.tb03016.x","url":null,"abstract":"Aggregates of various mammalian beta 2-microglobulin (beta 2m) homologues were tested in binding experiments with group A streptococcal strains of different M types. The binding patterns obtained were similar, suggesting that evolutionarily conserved parts of the beta 2m molecule are responsible for the interaction with group A streptococci. An N-terminally abnormal beta 2m showed binding characteristics similar to those of normal human beta 2m, indicating that the amino-terminal does not participate in this interaction. Aggregates of human IgG Fab fragments, kappa chains and lambda chains, were also analyzed. Whereas several of the beta 2m-reactive M types did not interact with any of these aggregates, all strains binding aggregated Fab, kappa or lambda, also bound aggregated beta 2m. Strains of M types 4, 12, 23 and 53 bound all the tested proteins; M type 1 bound all but IgG Fab, whereas M types 46, 49 and 53 showed affinity for beta 2m and lambda chains only. In inhibition experiments, unlabelled aggregated beta 2m in excess completely blocked the uptake of radiolabelled aggregated IgG Fab, kappa and lambda chains. Conversely, Fab, kappa and lambda aggregates inhibited the binding of radiolabelled beta 2m aggregates. Our results indicate that the differences in reactivity recorded between beta 2m and IgG Fab, kappa and lambda chains, all structurally related, are quantitative rather than qualitative. Thus, a common binding structure for these aggregated proteins on group A streptococci appears probable.","PeriodicalId":7045,"journal":{"name":"Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology","volume":"94 1","pages":"25-31"},"PeriodicalIF":0.0,"publicationDate":"1986-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1699-0463.1986.tb03016.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14220792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0