{"title":"Solitary Fibrous Tumor Developing Two Years After Primary Cranial Synovial Sarcoma: A Rare Case.","authors":"C Yazar, E Özkul, K Yazar, F T Sönmez","doi":"10.52628/92.1.15232","DOIUrl":"10.52628/92.1.15232","url":null,"abstract":"<p><p>Synovial sarcoma is an aggressive and rare malignant soft tissue neoplasm, typically affecting young adults and predominantly arising near major joints. Primary cranial involvement is extremely uncommon. In rare circumstances, patients may develop multiple soft tissue tumors either synchronously or metachronously, raising a challenging differential diagnosis between metastatic disease and a second primary malignancy. We report the case of a woman diagnosed with a primary high-grade cranial synovial sarcoma, treated with wide surgical resection followed by adjuvant radiotherapy, who remained disease-free for two years. She later presented with multifocal skeletal lesions. Biopsies taken from two distinct bone lesions demonstrated diffuse STAT6 positivity and the absence of SS18 rearrangement by molecular analysis. These features, confirmed by independent pathological reviews and a multidisciplinary tumor board, were consistent with a multifocal solitary fibrous tumor rather than metastatic disease. This rare case highlights the diagnostic complexity of multifocal skeletal lesions developing after primary cranial synovial sarcoma and emphasizes the importance of thorough pathological, molecular, and multidisciplinary evaluation.</p>","PeriodicalId":7018,"journal":{"name":"Acta orthopaedica Belgica","volume":"92 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147727877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effect of education on deep vein trombosis in patients undergoing orthopedic surgery: a meta-analysis study.","authors":"D Erden, M Civanoglu","doi":"10.52628/92.1.14713","DOIUrl":"10.52628/92.1.14713","url":null,"abstract":"<p><p>This meta-analysis study was conducted to evaluate the effect of education-based interventions on the development of deep vein thrombosis (DVT) in patients undergoing orthopedic surgery. In this study, the terms \"deep vein thrombosis,\" \"orthopedic surgery,\" and \"patient education\" were searched in Turkish and English in the relevant literature published in the last 20 years in the Web of Science, PubMed, ScienceDirect, Scopus, and Google Scholar databases. A total of 8021 studies were found as a result of the search. Six studies that met the inclusion criteria were reviewed. In the meta-analysis, the Odds Ratio (OR) was calculated as the effect size, and Cochran's Q test and I² statistic were used for heterogeneity analysis. Publication bias was assessed using funnel plots and Egger regression tests. The meta-analysis found that the risk of developing DVT was significantly lower in groups that received educational interventions compared to control groups (OR ≈ 0.50, 95% CI: 0.37-0.69, p <0.001). Educational interventions have been effective through mechanisms such as encouraging early mobilization, increasing compliance with anticoagulant medication use, and raising awareness about DVT symptoms (p <0.05). In orthopedic surgery patients, education-based interventions applied in conjunction with pharmacological and mechanical methods are effective in preventing DVT. Systematic integration of patient education programs into clinical practice will contribute significantly to improving patient safety and reducing postoperative complications. Future studies should focus on the integration of digital health technologies and the evaluation of long-term effects. The study has been registered with PROSPERO (CRD420251047966).</p>","PeriodicalId":7018,"journal":{"name":"Acta orthopaedica Belgica","volume":"92 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147727880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N Magida, H Myezwa, W Mudzi, E Musenge, S A Mohamed Khan, M A Graham
{"title":"Efficacy of low-intensity pulsed ultrasound in surgically managed lower limb fractures: a randomised controlled trial.","authors":"N Magida, H Myezwa, W Mudzi, E Musenge, S A Mohamed Khan, M A Graham","doi":"10.52628/92.1.12938","DOIUrl":"10.52628/92.1.12938","url":null,"abstract":"<p><p>Although there have been improvements in surgical fixation techniques, the process of fracture healing continues to pose challenges, especially for patients with additional health issues. Low-intensity pulsed ultrasound (LIPUS) has been proposed as a non-invasive method to facilitate faster bone recovery; however, its effectiveness in clinical settings remains unclear. This study aimed to assess the impact of LIPUS on the healing of lower limb fractures. A double-blinded, prospective, randomised controlled trial was conducted in two hospitals in Gauteng, South Africa. The study was approved by the University of the Witwatersrand (M150236). Ninety-four individuals aged 18 years and older with lower limb fractures were consecutively recruited and randomly assigned to either the LIPUS or control group. The intervention group underwent 20-minute LIPUS sessions every alternate day for a duration of 20 days during their hospitalisation, followed by follow-up after discharge. Callus formation, cortical bridging, fracture gap, and overall radiographic healing were evaluated at 6, 12, and 18 weeks. An intention-to- treat analysis was performed to accommodate missing radiographs and loss to follow-up. No statistically significant differences were found between the intervention and control groups concerning callus formation, cortical bridging, fracture gap, or overall healing at any assessment time. A high rate of loss to follow-up and unavailability of radiographs diminished the analysis's power. LIPUS did not show a notable improvement in fracture healing when compared to standard care. Its clinical use may need to be reevaluated, especially in low- and middle-income countries, where cost-effectiveness is a crucial factor.</p>","PeriodicalId":7018,"journal":{"name":"Acta orthopaedica Belgica","volume":"92 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147727912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J E Garcia-Rellan, A Subias Lopez, E Guillen Botaya, A Silvestre Muñoz
{"title":"Severe Wear and Metal Poisoning in Revision Surgery after Ceramic Fracture Treated with Dual Mobility Prosthesis.","authors":"J E Garcia-Rellan, A Subias Lopez, E Guillen Botaya, A Silvestre Muñoz","doi":"10.52628/91.4.13887","DOIUrl":"10.52628/91.4.13887","url":null,"abstract":"<p><p>The aim of this study was to analyze the outcomes of revision surgery for a broken ceramic when using a dual- mobility (DM) implant with a metallic inner head (CoCr). A retrospective analysis was conducted on 225 cases utilizing DM implants to evaluate complications. In cases where DM was used to treat a prior ceramic fracture, we assessed clinical outcomes, wear patterns, and metal-ion levels. Three cases requiring revision after ceramic fracture presented accelerated wear and marked metal-ion elevations, leading to significant morbidity and mortality. Metal debris and ceramic fragments were observed embedded in the polyethylene surfaces of the implants, particularly affecting the metal heads. Symptoms of systemic metal toxicity included fatigue, anorexia, auditory and visual symptoms, and cardiac complications. The use of DM prostheses following ceramic fractures poses significant risks of accelerated wear and metal poisoning. Notably, wear is much more pronounced in the internal metal head than in the insert. Clinical vigilance is essential to detect and manage complications promptly. After meticulous debridement, ceramic-on-ceramic or ceramic-on-polyethylene remain reasonable alternatives; our findings should not be generalized to standard DM applications.</p>","PeriodicalId":7018,"journal":{"name":"Acta orthopaedica Belgica","volume":"91 4","pages":"567-575"},"PeriodicalIF":0.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147607649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T Martins DA Silva, M F L Almeida Negreli, R C Diniz DE Souza, S B Guazzelli, A M Miranda
{"title":"Unilateral biportal endoscopy versus anterior cervical discectomy and fusion for cervical radiculopathy: a meta-analysis.","authors":"T Martins DA Silva, M F L Almeida Negreli, R C Diniz DE Souza, S B Guazzelli, A M Miranda","doi":"10.52628/91.4.14831","DOIUrl":"10.52628/91.4.14831","url":null,"abstract":"<p><p>The gold standard treatment for cervical radiculopathy is anterior cervical discectomy and fusion (ACDF). Our study compared ACDF with unilateral biportal endoscopy (UBE) to determine whether or not there is an advantage of the minimally invasive technique. PubMed, Embase, and Cochrane databases were searched for studies that compared UBE to ACDF for cervical radiculopathy. Statistical analysis was performed using Review Manager 5.4. Heterogeneity was examined with I² statistics and a random-effects model was used for all outcomes. Three studies comprising 509 patients with cervical radiculopathy were included. Of the participants studied, 255 underwent UBE (50.1%). There were no significant differences observed across the two groups in the change from baseline of NDI scores (MD: -0.17; 95% CI: -2.50 to 2.17), neck pain (SMD: -0.10; 95% CI: -0.53 to 0.33), and upper limb pain (SMD: -0.19; 95% CI: -0.43 to 0.06; p = 0.13). The UBE group showed a significant increase in operating time (MD: 19.78 min; 95% CI: 13.57 to 25.98 min) and a lower incidence of complications (0.051% vs. 0.094%; OR 0.52; 95% CI 0.25-1.08). UBE is an effective and safe alternative to ACDF, with no significant differences between the two approaches in terms of NDI scores or neck and arm pain. While the UBE group had a longer operating time, it exhibited a lower incidence of postoperative complications.</p>","PeriodicalId":7018,"journal":{"name":"Acta orthopaedica Belgica","volume":"91 4","pages":"347-355"},"PeriodicalIF":0.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147607652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S Gurbuz, A C Tekin, E Tasatan, M B Ayaz, M K Bayraktar, E Tekin
{"title":"Utilizing the Laser Aiming of Image Intensifier Reduces the Exposed Radiation During Operation: A Prospective Analysis.","authors":"S Gurbuz, A C Tekin, E Tasatan, M B Ayaz, M K Bayraktar, E Tekin","doi":"10.52628/91.4.13844","DOIUrl":"10.52628/91.4.13844","url":null,"abstract":"<p><p>Mobile C-arm units provide real-time intraoperative imaging but expose both patients and staff to ionizing radiation. This study aims to reveal if the use of the laser targeting feature of image intensifiers (available in most of the latest series) is beneficial for preventing radiation exposure. A randomized controlled trial was designed on the ankle fracture operations. Patients were randomly assigned to either the laser-targeting feature (LTF) group or the control group. The study group has an average age of 40.8 years, ranging from 16 to 71; 23 were men and 27 women. The control group has an average age of 32.8 years, ranging from 16 to 78; 21 were women and 29 men. An average of 23 (20-30) fluoroscopy shots were taken during surgery in the study group. In contrast, an average of 38 (34-48) fluoroscopy shots were taken during surgery in the control group. The duration of surgery in the study group was 40 minutes (36-55 mins), whereas in the control group, it was 47 minutes (40-65 mins). These findings suggest that integrated laser guidance may reduce radiation exposure during ankle fracture fixation surgery; however, multi-centre validation is warranted.</p>","PeriodicalId":7018,"journal":{"name":"Acta orthopaedica Belgica","volume":"91 4","pages":"539-545"},"PeriodicalIF":0.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147607667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Epithelioid Hemangioendothelioma of the Right Iliac Wing in a Young Adult Male: A Case Report.","authors":"M Wahyudi, E Kodrat, M Iskandar, A Rahadyan","doi":"10.52628/91.4.14665","DOIUrl":"10.52628/91.4.14665","url":null,"abstract":"<p><p>Epithelioid hemangioendothelioma (EHE) of bone is a malignant vascular neoplasm with a very low global prevalence. Nonspecific clinical and histopathological findings make the diagnosis of this tumor very challenging. In this case, we reported a 23-year-old male presented with persistent right buttock pain for 9 months (VAS 2-3). No other clinical findings were found. On plain radiographs, a lytic lesion was found on the right iliac wing. MRI showed iso- hyperintense lesions on both T1- and T2-weighted sequences with hemorrhagic components. A CT guided core needle biopsy was performed for further evaluation. The patient underwent wide excision with adjuvant chemotherapy. At six months post-surgery, lymph node metastases was found on PET scan without any clinical symptoms. A comprehensive interdisciplinary evaluation is required to establish the diagnosis of EHE.</p>","PeriodicalId":7018,"journal":{"name":"Acta orthopaedica Belgica","volume":"91 4","pages":"577-581"},"PeriodicalIF":0.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147607702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tenosynovial Giant Cell Tumor masked as de Quervain Tenosynovitis.","authors":"Q Diegenant, R Sciot, I Degreef","doi":"10.52628/91.4.13974","DOIUrl":"10.52628/91.4.13974","url":null,"abstract":"<p><p>We present a patient who initially presented with clinical symptoms consistent with de Quervain tenosynovitis, resistant to conservative treatment. MRI revealed a cystic mass surrounding the radial styloid within the first extensor compartment (abductor pollicis longus (APL) and extensor pollicis brevis (EPB)), associated with scaphotrapezoid (STT) arthritis. However, upon surgical exploration, the lesion was identified as a localized tenosynovial giant cell tumor (TSGCT), which had caused erosion of the trapezium bone and compressed the EPB tendon. Histopathology confirmed the diagnosis. Postoperative recovery was uneventful, with functional improvement and no recurrence. This exceptional case highlights the importance of accurate diagnosis and the potential for atypical presentations of benign tumors. Informed consent was obtained from the patient after surgery to use her case details in publication for educational and research purposes.</p>","PeriodicalId":7018,"journal":{"name":"Acta orthopaedica Belgica","volume":"91 4","pages":"583-587"},"PeriodicalIF":0.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147607659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lipocalin-2 and Bone Loss: A Brief Review.","authors":"M Mohammadi, A Jalali","doi":"10.52628/91.4.14943","DOIUrl":"10.52628/91.4.14943","url":null,"abstract":"<p><strong>Background: </strong>Recent research has redefined bone as an active endocrine organ with diverse physiological functions beyond structural support. Among the hormones secreted by osteoblasts, lipocalin 2 (LCN2) has gained attention for its dual roles in regulating bone metabolism and systemic energy balance.</p><p><strong>Materials: </strong>A comprehensive review of the literature was conducted, focusing on experimental and clinical studies that investigate LCN2 secretion by osteoblasts, its impact on bone remodeling, and its systemic effects on appetite regulation and energy homeostasis.</p><p><strong>Results: </strong>LCN2 acts as a context-dependent regulator of bone metabolism. Evidence indicates that it promotes bone formation under certain conditions while also stimulating bone resorption in others. Beyond the skeleton, LCN2 serves as a potent anorexigenic hormone, linking bone-derived signals to appetite control and systemic energy regulation.</p><p><strong>Conclusion: </strong>LCN2 represents a key mediator at the intersection of skeletal health and systemic metabolism. Its dual effects on bone remodeling and its ability to regulate appetite highlight its potential as a therapeutic target for managing skeletal diseases and metabolic disorders.</p>","PeriodicalId":7018,"journal":{"name":"Acta orthopaedica Belgica","volume":"91 4","pages":"447-452"},"PeriodicalIF":0.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147607671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Critical shoulder angle does not correlate with patient outcomes after arthroscopic rotator cuff repair.","authors":"M López-Franco, E Serrano Gil, D García García","doi":"10.52628/91.4.14881","DOIUrl":"10.52628/91.4.14881","url":null,"abstract":"<p><p>The aim of this study was to investigate the association between the critical shoulder angle (CSA) and the clinical outcomes following arthroscopic rotator cuff repair (RCR). An ambispective study was conducted in patients who underwent arthroscopic RCR and had adequate preoperative radiological shoulder studies (type A and 1 according to Suter and Henninger). Fifty-six patients with a minimum prospective follow-up of 3 years were included: 28 with a CSA >35º and 28 with a CSA <35º prior to surgery. At the follow-up, shoulder function was evaluated using the Constant-Murley score (CS), the Simple Shoulder Test (SST), the Quick DASH Scoring (QDS) and the Visual Analog Pain Score (VAS). The median CS showed no significant difference between groups: CSA <35º was 67.8 (IQR 27.8) and CSA ≥35º was 69.3 (IQR 39.6) (p=0.606). For the CSA <35º group, median SST, QDS and VAS scores were 75 (IQR 31.3); 6.8 (IQR 22.2) and 3.0 (IQR 4.8) respectively. In the CSA ≥35º group, the corresponding values were 75 (IQR 47.9); 11.3 (IQR 31.2) and 2.5 (IQR 7.0) respectively (all n.s.). Although scapular geometry has been implicated in the pathogenesis of rotator cuff disease, and both AI and CSA are simple radiographic tools, our results suggest that these parameters are not clinically relevant predictors of functional outcomes following arthroscopic RCR.</p>","PeriodicalId":7018,"journal":{"name":"Acta orthopaedica Belgica","volume":"91 4","pages":"479-486"},"PeriodicalIF":0.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147607533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}