Acta medica Scandinavica最新文献

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The primary preventive study in Uppsala. Fatal and non-fatal myocardial infarction during a 10-year follow-up of a middle-aged male population with treatment of high-risk individuals. 乌普萨拉的初级预防研究。致死性和非致死性心肌梗死在10年随访的中年男性人群与治疗高危个体。
Acta medica Scandinavica Pub Date : 1984-01-01
H Lithell, H Aberg, I Selinus, H Hedstrand
{"title":"The primary preventive study in Uppsala. Fatal and non-fatal myocardial infarction during a 10-year follow-up of a middle-aged male population with treatment of high-risk individuals.","authors":"H Lithell,&nbsp;H Aberg,&nbsp;I Selinus,&nbsp;H Hedstrand","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A health survey of middle-aged men was carried out in 1970-73 in the municipality of Uppsala. Subjects with hypertension, hyperlipidaemia, reduced glucose tolerance, and smokers were invited to join various therapy groups. By 1980 this multifactorial intervention programme had thus been running for 10 years. This report describes the results of a follow-up undertaken to evaluate the efficacy of the programme. The annual rate of fatal myocardial infarction (MI) was lower among the participants (n = 2322) in the health examination as well as among participants and non-participants (n = 446) combined than among the male Swedish population of the same age (162 and 187 compared with 296 per 100 000 men, respectively). The annual rate of non-fatal MI among participants and non-participants combined was 295 per 100 000 men, which is lower than in other Swedish cities. In the hypertensive group (n = 126), six men had fatal and seven non-fatal MI. These 13 men had higher blood pressures (BPs) from the start than the other hypertensives. In addition, their BP reduction was smaller than in a control group randomly selected among the hypertensive subjects. In the hyperlipidaemic treatment group (n = 363) there were eight fatal and 10 non-fatal MIs. Nine of these events occurred in individuals who had dropped out from therapy. It is suggested that the low total mortality and the low rates of fatal and non-fatal MI in this middle-aged male population may be related to the multifactorial intervention programme, as the incidences were also low among the treated high-risk groups.</p>","PeriodicalId":7011,"journal":{"name":"Acta medica Scandinavica","volume":"215 5","pages":"403-9"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17794807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Survival in end-stage diabetic renal disease. A prospective study of 100 kidney transplant patients. 终末期糖尿病肾病患者的生存率。100例肾移植患者的前瞻性研究。
Acta medica Scandinavica Pub Date : 1984-01-01
O Larsson, P O Attman, M Aurell, B Frisk, H Brynger
{"title":"Survival in end-stage diabetic renal disease. A prospective study of 100 kidney transplant patients.","authors":"O Larsson,&nbsp;P O Attman,&nbsp;M Aurell,&nbsp;B Frisk,&nbsp;H Brynger","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The results of renal transplantation in patients with diabetes mellitus were studied in 100 consecutive patients transplanted between Dec. 1972 and June 1982. The study period was divided into two parts, 1972-76 (era I, 21 patients, 18 with juvenile onset diabetes) and 1977-82 (era II, 79 patients, 72 with juvenile onset diabetes). A group of 168 non-diabetic patients, aged 20-54 years, receiving primary grafts during the same period served as controls to the 72 juvenile onset diabetics from era II. The three-year actuarial patient survival of transplanted diabetics improved from 48% during era I to 76% during era II and was then not significantly inferior to that of the non-diabetic controls. The three-year actuarial graft survival rate was significantly higher for recipients of kidneys from living related donors than for those who had received kidneys from cadaveric donors (CD) among both diabetic and non-diabetic patients. However, the three-year graft survival rate was significantly higher (56%) for non-diabetic than diabetic CD recipients (37%). The overall survival in diabetes mellitus was strongly influenced by the outcome of retransplantation during era II (12 patients). Thus, 69 patients were alive, 64 with a functioning graft, at the end of the observation period.</p>","PeriodicalId":7011,"journal":{"name":"Acta medica Scandinavica","volume":"216 4","pages":"393-402"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17452524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Kockum study: twenty-two-year follow-up. Coronary heart disease in a population in the south of Sweden. Kockum研究:22年随访。瑞典南部人群的冠心病。
Acta medica Scandinavica Pub Date : 1984-01-01
B Persson, B W Johansson
{"title":"The Kockum study: twenty-two-year follow-up. Coronary heart disease in a population in the south of Sweden.","authors":"B Persson,&nbsp;B W Johansson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The Kockum study of risk factors for coronary heart disease (CHD) consists of 464 individuals, one third white collar workers, one third heavy workers and one third well trained firemen, all of whom have now been followed for 22 years. Important risk factors for CHD seem to be heredity, smoking, stress, lack of physical activity, diabetes mellitus hypertension, high body weight, ECG abnormalities, hypercholesterolemia, hypertriglyceridemia and baldness. In addition to the common risk factors, baldness seems to be of importance. A high cholesterol value predisposes for an increased death rate not only due to CHD but also to malignant disease. A Cox analysis shows a markedly decreased life expectancy in multirisk factor patients caused not only by CHD but also by cancer.</p>","PeriodicalId":7011,"journal":{"name":"Acta medica Scandinavica","volume":"216 5","pages":"485-93"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17580233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cardiac dysrhythmias in patients with acute myocardial infarction. Relation to serum potassium level and prior diuretic therapy. 急性心肌梗死患者的心律失常。血清钾水平与既往利尿剂治疗的关系。
Acta medica Scandinavica Pub Date : 1984-01-01
T Dyckner, C Helmers, P O Wester
{"title":"Cardiac dysrhythmias in patients with acute myocardial infarction. Relation to serum potassium level and prior diuretic therapy.","authors":"T Dyckner,&nbsp;C Helmers,&nbsp;P O Wester","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A series of 676 patients with acute myocardial infarction were evaluated with regard to initial serum potassium level, prior diuretic therapy and occurrence of cardiac dysrhythmias during their first 24 hours in a coronary care unit. Serious dysrhythmias (ventricular tachycardia, ventricular fibrillation, and asystole) were significantly more frequent in hypokalemic patients. In this regard no differences were observed between patients on or off prior diuretic therapy.</p>","PeriodicalId":7011,"journal":{"name":"Acta medica Scandinavica","volume":"216 1","pages":"127-32"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17544374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acta Medica Scandinavia Award 1984. Hans Orskov. 1984年斯堪的纳维亚医学奖。汉斯·奥尔斯科夫。
Acta medica Scandinavica Pub Date : 1984-01-01
{"title":"Acta Medica Scandinavia Award 1984. Hans Orskov.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7011,"journal":{"name":"Acta medica Scandinavica","volume":"216 4","pages":"341-3"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17453746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Raynaud's phenomenon caused by beta-receptor blocking drugs. Improvement after treatment with a combined alpha- and beta-blocker. 由受体阻断药物引起的雷诺氏现象。联合-受体阻滞剂治疗后的改善。
Acta medica Scandinavica Pub Date : 1984-01-01
K Eliasson, M Danielson, B Hylander, L E Lindblad
{"title":"Raynaud's phenomenon caused by beta-receptor blocking drugs. Improvement after treatment with a combined alpha- and beta-blocker.","authors":"K Eliasson,&nbsp;M Danielson,&nbsp;B Hylander,&nbsp;L E Lindblad","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Twenty-four hypertensive patients reported vasospastic symptoms in their hands during treatment with beta-blocking drugs with different pharmacological properties. Twenty patients had symptoms when staying indoors and 11 did not always experience complete relief of symptoms following active rewarming attempts. Finger systolic blood pressures were measured after standardized local cooling. In 15 patients, blood pressure decreased to a pathological level during this procedure. Previous beta-blockade was changed to combined alpha- and beta-blockade with labetalol given twice daily in a mean dose of 259 mg/day for 3 months. After this period, most patients showed a decreased temperature sensitivity both objectively and subjectively. Blood pressure control was maintained at the previous level. Heart rate increased significantly during treatment with labetalol. Labetalol offers an alternative treatment to patients suffering from vasospastic side-effects of beta-blockers.</p>","PeriodicalId":7011,"journal":{"name":"Acta medica Scandinavica","volume":"215 4","pages":"333-9"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17211078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hematogenous Candida spondylitis. A case report. 血念珠菌脊柱炎。一份病例报告。
Acta medica Scandinavica Pub Date : 1984-01-01
S Pohjola-Sintonen, P Ruutu, K Tallroth
{"title":"Hematogenous Candida spondylitis. A case report.","authors":"S Pohjola-Sintonen,&nbsp;P Ruutu,&nbsp;K Tallroth","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 58-year-old patient with neutropenia due to SLE developed spondylitis of the lumbar region caused by Candida albicans. The spondylitis was probably superinfected with Staphylococcus aureus. The initial one month's intravenous combination therapy with amphotericin B and flucytosine was discontinued because of fever reactions to amphotericin B, suspected myelosuppressive effect of flucytosine and insufficient clinical response. This therapy was followed by four months of oral ketoconazole and clindamycin with good results and without any side-effects.</p>","PeriodicalId":7011,"journal":{"name":"Acta medica Scandinavica","volume":"215 1","pages":"85-7"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17381767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The etiology of "sports anemia". A physiological adaptation of the oxygen-dissociation curve of hemoglobin to an unphysiological exercise load. “运动性贫血”的病因。血红蛋白氧解离曲线对非生理性运动负荷的生理适应。
Acta medica Scandinavica Pub Date : 1984-01-01
L Hallberg, B Magnusson
{"title":"The etiology of \"sports anemia\". A physiological adaptation of the oxygen-dissociation curve of hemoglobin to an unphysiological exercise load.","authors":"L Hallberg,&nbsp;B Magnusson","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7011,"journal":{"name":"Acta medica Scandinavica","volume":"216 2","pages":"147-8"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17553201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thiazide prophylaxis of urolithiasis. A double-blind study in general practice. 噻嗪预防尿石症。一般情况下的双盲研究。
Acta medica Scandinavica Pub Date : 1984-01-01
E Laerum, S Larsen
{"title":"Thiazide prophylaxis of urolithiasis. A double-blind study in general practice.","authors":"E Laerum,&nbsp;S Larsen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Fifty recurrent stone formers were included in a double-blind randomized study (median 3 years) performed in a Norwegian general practice to compare twice daily administration of 25 mg hydrochlorothiazide versus placebo. The number of patients with new stones was significantly higher in the placebo group than in the thiazide group (p = 0.05, one-tailed test). If a new stone was formed, thiazide, but not placebo, had the effect of prolonging the stone-free interval (p less than or equal to 0.01). The probability of not forming a new stone during the treatment period was 45% for the placebo group and 75% for the thiazide group. The thiazide effect seemed to be independent of urinary calcium, but was less beneficial in patients with hyperuricosuria. The placebo group also showed a substantial decrease in the expected number of new stones (p less than or equal to 0.01), emphasizing the importance of an adequate control group.</p>","PeriodicalId":7011,"journal":{"name":"Acta medica Scandinavica","volume":"215 4","pages":"383-9"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17434899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Heart and kidney involvement during antihypertensive treatment. Results from the primary preventive trial in Göteborg, Sweden. 抗高血压治疗中心脏和肾脏受累。瑞典Göteborg初级预防试验的结果。
Acta medica Scandinavica Pub Date : 1984-01-01
O Samuelsson, J Wikstrand, L Wilhelmsen, G Berglund
{"title":"Heart and kidney involvement during antihypertensive treatment. Results from the primary preventive trial in Göteborg, Sweden.","authors":"O Samuelsson,&nbsp;J Wikstrand,&nbsp;L Wilhelmsen,&nbsp;G Berglund","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The prevalence of signs of heart (Minnesota-coded ECG, chest X-ray) and kidney involvement (proteinuria, abnormal serum creatinine) was studied before and after 5 years' antihypertensive treatment in 686 middle-aged, hypertensive men derived from a screening examination of a random population sample. The prevalences of heart enlargement (X-ray) and abnormally high serum creatinine increased. A pronounced regression of S-T and T wave changes in the ECG was achieved. In a subgroup of 375 patients without digitalis therapy and not having had myocardial infarction, ECG signs of left ventricular hypertrophy decreased.</p>","PeriodicalId":7011,"journal":{"name":"Acta medica Scandinavica","volume":"215 4","pages":"305-11"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17296486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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