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Acta medica Scandinavica最新文献

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Analgetic treatment in acute myocardial infarction. A controlled clinical comparison of morphine, nicomorphine and pethidine. 急性心肌梗死的镇痛治疗。吗啡、硝吗啡和哌替啶的对照临床比较。
Acta medica Scandinavica Pub Date : 1984-01-01
J R Nielsen, K E Pedersen, C G Dahlstrøm, B L Nielsen, B Secher, T Johansen, L F Gram
{"title":"Analgetic treatment in acute myocardial infarction. A controlled clinical comparison of morphine, nicomorphine and pethidine.","authors":"J R Nielsen,&nbsp;K E Pedersen,&nbsp;C G Dahlstrøm,&nbsp;B L Nielsen,&nbsp;B Secher,&nbsp;T Johansen,&nbsp;L F Gram","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In a randomized double-blind study with flexible dosage, morphine, nicomorphine and pethidine were compared with regard to analgetic effect, dose requirements, dose intervals and adverse reactions. A total of 275 patients were included, and 28 patients were excluded due to adverse reactions (n = 16) and for practical reasons, etc. Acute myocardial infarction (AMI) was diagnosed in about 60% of the patients, and about 30% had ischemic heart disease without AMI. All three analgesics provided equally efficient pain relief in relative doses of morphine 10, nicomorphine 10 and pethidine 75 mg/ml. Severe adverse reactions were few (allergy 3 cases, respiratory insufficiency 4, severe bradycardia 4), whereas nausea was recorded in 20-30%, vomiting in 5-15% and dizziness in 10-30% of the patients, with no difference between the three drugs. Significant blood pressure drop (greater than 30 mmHg) was seen in 3-8% of the patients, with no significant differences between the drugs.</p>","PeriodicalId":7011,"journal":{"name":"Acta medica Scandinavica","volume":"215 4","pages":"349-54"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17435113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Visual disturbances and occipital brain infarct following acute, transient hypotension in hypertensive patients. 高血压患者急性、短暂性低血压后的视觉障碍和枕脑梗死。
Acta medica Scandinavica Pub Date : 1984-01-01
S Strandgaard, G S Andersen, P Ahlgreen, P E Nielsen
{"title":"Visual disturbances and occipital brain infarct following acute, transient hypotension in hypertensive patients.","authors":"S Strandgaard,&nbsp;G S Andersen,&nbsp;P Ahlgreen,&nbsp;P E Nielsen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In four hypertensive patients, acute lowering of blood pressure by therapeutic or diagnostic procedures caused visual disturbances ranging from transient visual hallucinations to severe, long-lasting visual impairment. These symptoms were associated with occipital lobe cerebral infarcts that tended to occur in the border zones between the major cerebral arteries. The infarcts may be seen as the combined result of a \"watershed\" effect during acute hypotension and the presence of structural hypertensive vascular adaptation. When a hypertensive patient complains of visual disturbances during acute blood pressure lowering, the pressure should be allowed to settle at a level somewhat above normal.</p>","PeriodicalId":7011,"journal":{"name":"Acta medica Scandinavica","volume":"216 4","pages":"417-22"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17574567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Side-effects of piroxicam (Feldene). A one-year material of 103 reports from Norway. 吡罗西康(Feldene)的副作用。一年的材料，来自挪威的103份报告。
Acta medica Scandinavica Pub Date : 1984-01-01
K Laake, L Kjeldaas, C F Borchgrevink
{"title":"Side-effects of piroxicam (Feldene). A one-year material of 103 reports from Norway.","authors":"K Laake,&nbsp;L Kjeldaas,&nbsp;C F Borchgrevink","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the first year after registration, 103 reports on suspected adverse reaction to piroxicam (Feldene) were submitted to the Norwegian Adverse Drug Reaction Committee. Eighty-three reactions were classified as probable side-effects, and 73 of these were related to the upper gastrointestinal tract. Peptic ulcer and upper gastrointestinal haemorrhages predominated. Two deaths were classified as probably due to piroxicam. There were 8 life-threatening reactions, all due to haemorrhages. No severe cutaneous reactions were reported. A significant fraction of the gastrointestinal reactions occurred in patients with a previous history of peptic ulcer disease. Nearly every fourth patient with proven ulcer or haematemesis/melaena had simultaneously been taking other drugs with the propensity of causing gastrointestinal haemorrhage. The gastrointestinal adverse reactions to piroxicam can probably be reduced by a more accurate selection of patients.</p>","PeriodicalId":7011,"journal":{"name":"Acta medica Scandinavica","volume":"215 1","pages":"81-3"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17749651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Morbidity and mortality in relation to blood pressure and antihypertensive treatment. A 12-year follow-up study of a population sample of Swedish women. 发病率和死亡率与血压和抗高血压治疗的关系。一项对瑞典女性人口样本进行的为期12年的跟踪研究。
Acta medica Scandinavica Pub Date : 1984-01-01
J A Sigurdsson, C Bengtsson, L Lapidus, O Lindquist, V Rafnsson
{"title":"Morbidity and mortality in relation to blood pressure and antihypertensive treatment. A 12-year follow-up study of a population sample of Swedish women.","authors":"J A Sigurdsson,&nbsp;C Bengtsson,&nbsp;L Lapidus,&nbsp;O Lindquist,&nbsp;V Rafnsson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Morbidity and mortality in cardiovascular and cerebrovascular diseases and total mortality have been studied in a longitudinal population study initially comprising 1462 women representative of the general female population. When related to the initial blood pressure (BP) levels of women not on antihypertensive drugs (hypertensives and non-hypertensives), the distributions of women with myocardial infarction (MI) and stroke during the 12-year follow-up period seemed to be U-shaped, with the highest incidences in women with the lowest and the highest BP levels. Women recognized as untreated hypertensives in the initial study were offered regular control by the study team during the whole 12-year period and were treated when treatment was considered indicated. They were found to be similar to the non-hypertensives with regard to the incidence of MI and stroke and total mortality. Our encouraging results may be explained by continuity of medical care, the antihypertensive treatment per se or the types of antihypertensive drugs administered.</p>","PeriodicalId":7011,"journal":{"name":"Acta medica Scandinavica","volume":"215 4","pages":"313-22"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17784331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Heparin-induced increase in serum levels of aminotranferases. A controlled clinical trial. 肝素诱导的血清转氨酶水平升高。对照临床试验。
Acta medica Scandinavica Pub Date : 1984-01-01
H K Nielsen, S E Husted, H D Koopmann, H Fasting, O Simonsen, K Andersen, H C Husegaard, T K Petersen
{"title":"Heparin-induced increase in serum levels of aminotranferases. A controlled clinical trial.","authors":"H K Nielsen,&nbsp;S E Husted,&nbsp;H D Koopmann,&nbsp;H Fasting,&nbsp;O Simonsen,&nbsp;K Andersen,&nbsp;H C Husegaard,&nbsp;T K Petersen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Sixty-four patients over the age of 40 years, undergoing elective surgery of at least one hour's duration, were randomized to treatment with either a thromboembolic deterrent ( TED ) stocking (Kendall Co.) or subcutaneous low-dose heparin 5 000 IU every 12 hours. Serum levels of alanine aminotransferase (S-ALAT), aspartate aminotransferase (S-ASAT), gamma-glutamyl transpeptidase (S-gamma-GT) and alkaline phosphatase (S-ALP) were measured. S-ALAT increased significantly on the 5th and 10th postoperative day, from 27 +/- 2 (x +/- SE) to 40 +/- 4 (p less than 0.01) and 55 +/- 7 U/l (p less than 0.001), respectively, in the heparin group and was significantly higher in the heparin than in the TED group both on the 5th (p less than 0.01) and 10th (p less than 0.05) postoperative day. S-ASAT and S-gamma-GT increased significantly during heparin treatment, but did not differ significantly from the values of the TED group. No change in S-ALP was registered in either group. It is concluded that prophylactic treatment with low-dose heparin induces a significant increase in S-aminotransferase levels, especially in S-ALAT. The phenomenon has profound differential diagnostic implications in conditions such as pulmonary embolism and acute myocardial infarction.</p>","PeriodicalId":7011,"journal":{"name":"Acta medica Scandinavica","volume":"215 3","pages":"231-3"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17435112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Are we overtreating hypertension? 我们过度治疗高血压了吗?
Acta medica Scandinavica Pub Date : 1984-01-01
G Berlund
{"title":"Are we overtreating hypertension?","authors":"G Berlund","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7011,"journal":{"name":"Acta medica Scandinavica","volume":"216 4","pages":"337-9"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17575692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cardioversion during pregnancy. A case report. 怀孕期间的心脏复律。一份病例报告。
Acta medica Scandinavica Pub Date : 1983-01-01
I Cullhed
{"title":"Cardioversion during pregnancy. A case report.","authors":"I Cullhed","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A case of atrial fibrillation during pregnancy in a 20-year-old patient with valvular heart disease is presented. Synchronized direct-current cardioversion was carried out successfully during monitoring of maternal and fetal ECG. Previously published cases are reviewed.</p>","PeriodicalId":7011,"journal":{"name":"Acta medica Scandinavica","volume":"214 2","pages":"169-72"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17680126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Familial amyloidosis with polyneuropathy. A long-term follow-up of 21 patients with special reference to gastrointestinal symptoms. 家族性淀粉样变性伴多发性神经病变。对21例有特殊胃肠道症状的患者进行长期随访。
Acta medica Scandinavica Pub Date : 1983-01-01
L Steen, B Ek
{"title":"Familial amyloidosis with polyneuropathy. A long-term follow-up of 21 patients with special reference to gastrointestinal symptoms.","authors":"L Steen,&nbsp;B Ek","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In a longitudinal study, 21 patients with familial amyloidosis with polyneuropathy (FAP) were followed up for more than three years. Gastrointestinal symptoms ultimately evolved in all patients. In the advanced stage of the disease, 13 patients had diarrhea together with anal incontinence. Weight loss was very common and related to both malabsorption and motility disturbances with anorexia and also to muscular atrophy. Steatorrhea was found in 19 patients at least once during the follow-up. The duration of the disease was significantly correlated to fecal fat output. The conclusion was drawn that the gastrointestinal involvement in FAP is very common and of great clinical importance. The consequences of malnutrition also influence the outcome of the disease.</p>","PeriodicalId":7011,"journal":{"name":"Acta medica Scandinavica","volume":"214 5","pages":"387-97"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17714666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictive value of arterial blood pressure in old age. A ten-year prospective study of men and women born in 1897 and examined at the age of 70 and 80 years. 老年动脉血压的预测价值。这是一项对1897年出生的男性和女性进行的为期十年的前瞻性研究，研究对象分别是70岁和80岁。
Acta medica Scandinavica Pub Date : 1983-01-01
E Agner
{"title":"Predictive value of arterial blood pressure in old age. A ten-year prospective study of men and women born in 1897 and examined at the age of 70 and 80 years.","authors":"E Agner","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In a 10-year longitudinal study of men and women aged exactly 70 at entry and otherwise only selected according to geography, the predictive value of arterial blood pressure was evaluated concerning cardiovascular disease (CVD) at entry and CVD development or death during the following decade. At 70 the prevalence of arterial hypertension (greater than or equal to 160/95 mmHg) was 46% in men and 45% in women. At 80 these prevalences were 19 and 30%, respectively. In women, this fall could partly be explained by an association between high blood pressure and excess mortality. In both sexes it could partly be explained by an increasing part of the population being treated with antihypertensives/diuretics, partly by an association with myocardial degeneration. In a Cox's regression model for competing risks at 70, high systolic blood pressure had independent, predictive value for excess CVD mortality in the eighth decade in women alone, and for excess CVD development in both sexes. High diastolic blood pressure had no independent predictive value for any of these end points.</p>","PeriodicalId":7011,"journal":{"name":"Acta medica Scandinavica","volume":"214 4","pages":"285-94"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17714852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bone marrow necrosis. Report of a case and a brief review of the literature. 骨髓坏死。报告一个病例并简要回顾文献。
Acta medica Scandinavica Pub Date : 1983-01-01
P V Hansen, J Andersen, H Mygind
{"title":"Bone marrow necrosis. Report of a case and a brief review of the literature.","authors":"P V Hansen,&nbsp;J Andersen,&nbsp;H Mygind","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Bone marrow necrosis (BMN) is a rare finding in specimens from living patients. It is most commonly found in patients with neoplastic disorders, severe infections and sickle cell disease. We present a patient with Hodgkin's disease who developed extensive BMN 11 months before death. A concise review of the literature is also presented.</p>","PeriodicalId":7011,"journal":{"name":"Acta medica Scandinavica","volume":"214 4","pages":"331-6"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17714664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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