Acta histochemica. Supplementband最新文献_第10页

The occurrence of carbohydrate antigens (CA 19-9, CA-50) in chronic pancreatitis and pancreatic carcinoma. 慢性胰腺炎和胰腺癌中糖类抗原(CA 19-9、CA-50)的发生。

Acta histochemica. Supplementband Pub Date : 1990-01-01

J Schwenk, J Makovitzky

引用次数: 0

Chromogranin A in the endocrine pancreas: extracellular or intracellular function? 胰腺内分泌嗜铬粒蛋白A:细胞外功能还是细胞内功能?

Acta histochemica. Supplementband Pub Date : 1990-01-01

M Ehrhart, M Gratzl

引用次数: 0

Inhibition of tumour development in the partially resected, proliferating rat urinary bladder. 部分切除增殖大鼠膀胱肿瘤发展的抑制作用。

Acta histochemica. Supplementband Pub Date : 1990-01-01

E Kunze

{"title":"Inhibition of tumour development in the partially resected, proliferating rat urinary bladder.","authors":"E Kunze","doi":"","DOIUrl":"","url":null,"abstract":"Autoradiographic studies have shown that the urothelium of the rat urinary bladder is capable to considerably proliferate in response to a partial cystectomy (one-third resection of the bladder) as is indicated by a 190-fold increase of the 3H-thymidine labelling index above normal levels 45 h postoperatively and an enormous increase of the compartment of proliferating cells (so-called growth fraction). The stimulated urothelial proliferation can be synchronized by multiple, fractionated doses of hydroxyurea (HU), resulting in a high degree of synchrony. Based on these findings, the partial cystectomy model seemed to be a useful tool to examine whether stimulated proliferation exerts a modifying effect on initiation of urothelial carcinogenesis. Following feeding N-butyl-N-(4-hydroxybutyl)-nitrosamine by gavage in 3 fractionated doses during most pronounced proliferation 30, 45 and 70 h postoperatively, the development of bladder tumors proved to be significantly dose- and time-related inhibited. Accordingly, N-methyl-N-nitrosourea (MNU)-induced tumour formation was considerably reduced following intravesicular instillation of the carcinogen at a single dose 45 h postoperatively, when stimulated DNA synthesis reached its peak. Experiments testing a possible cell cycle specific dependence of MNU-initiated tumor development in the partially resected bladder after synchronization of the stimulated proliferation by HU revealed an inhibition of urothelial carcinogenesis in particular, when the carcinogen was administered during the early DNA synthesis phase. The mechanisms underlying the observed inhibition of tumor development in the regeneration urinary bladder are unknown. It is assumed that an increased capacity of the proliferating urothelial cells to repair carcinogen-induced DNA-damage may play an important role.","PeriodicalId":7002,"journal":{"name":"Acta histochemica. Supplementband","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13235542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Structural changes within mixed populations of microtubules and protofilament ribbons caused by dilution and cold incubation. 稀释和冷孵育引起的微管和原丝带混合种群的结构变化。

Acta histochemica. Supplementband Pub Date : 1990-01-01

H Müller, K J Böhm, W Vater, E Unger

引用次数: 0

[X-ray microanalysis--possibilities and methods]. [x射线微量分析——可能性和方法]。

Acta histochemica. Supplementband Pub Date : 1990-01-01

T von Zglinicki

引用次数: 0

Biological, biochemical and morphological markers of breast disorders and of breast cancer. 乳腺疾病和乳腺癌的生物学、生化和形态学标记。

Acta histochemica. Supplementband Pub Date : 1990-01-01

A J Leathem

引用次数: 0

Immunocytochemical localization of the intracellular sites of sialylation in rat hepatocytes and colonic epithelial cells. 大鼠肝细胞和结肠上皮细胞唾液化位点的免疫细胞化学定位。

Acta histochemica. Supplementband Pub Date : 1990-01-01

D J Taatjes

引用次数: 0

[Submicroscopic indication of pathological cell growth in hypertrophic cardiomyopathy (HCM) in humans]. [人类肥厚性心肌病(HCM)病理细胞生长的亚显微镜指示]。

Acta histochemica. Supplementband Pub Date : 1990-01-01

C H Becker, V Boewer, J Waigand

{"title":"[Submicroscopic indication of pathological cell growth in hypertrophic cardiomyopathy (HCM) in humans].","authors":"C H Becker, V Boewer, J Waigand","doi":"","DOIUrl":"","url":null,"abstract":"The increasing application of transvascular endomyocardial biopsy for diagnostic verification of various heart diseases and elucidation of their etiology relies mainly on light microscopical methods. It is shown by hypertrophic cardiomyopathy as an example that also submicroscopical findings may be of value in diagnostic work, prognosis, and investigating research for etiological relationships. Specific morphological markers for idiopathic HCM were not demonstrable; nevertheless, some characteristic alterations such as fibrillary disorder, excessive folding of nuclear-, intercalated disc-, and sarcolemmal membranes, contraction bands, accumulation of mitochondria, glycogen, and lipid droplets, among others as well as sometimes the thickening of vascular walls with its unknown relations to the so-called \"small vessel disease\" may be helpful when endomyocardial biopsies are examined with the electron microscope too. Though many cytomorphologic findings are similar to those in dilatative cardiomyopathy, this disease probably is not a final state of HCM. In order to prove the actual cause of both heart failures, more intensive investigating research especially at the molecular biological level is required.","PeriodicalId":7002,"journal":{"name":"Acta histochemica. Supplementband","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13304223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cytochemical markers of neural and endocrine cells. XXX. Symposium of the International Association of Histochemists. Gargellen, Austria, September 21-24, 1988. Proceedings. 神经和内分泌细胞的细胞化学标记物。XXX。国际组织化学家协会研讨会。1988年9月21日至24日，奥地利加格伦。程序。

Acta histochemica. Supplementband Pub Date : 1990-01-01

引用次数: 0

[Chromogranins in endocrine cells of the digestive system]. [消化系统内分泌细胞中的嗜铬颗粒]。

Acta histochemica. Supplementband Pub Date : 1990-01-01

D Grube, G Bargsten, Y Cetin, A Jörns, S Yoshie

引用次数: 0