ACS Applied Nano Materials最新文献_第9页

Sustainable Manufacturing of Vertical Carbon Nanotube (CNT) Arrays Inside Insulating Nanoporous Membranes Using Nickel Magnetic Nanowires (MNWs) 利用镍磁纳米线 (MNW) 在绝缘纳米多孔膜内可持续地制造垂直碳纳米管 (CNT) 阵列

IF 5.3 2区材料科学

ACS Applied Nano Materials Pub Date : 2024-10-18 DOI: 10.1021/acsanm.4c0478210.1021/acsanm.4c04782

Roman Kolisnyk*, Morgen L. Smith, Nicholas C. A. Seaton, Michael L. Odlyzko, Olha Masiuchok, Jeanne Riga, Placidus B. Amama and Bethanie J. H. Stadler*,

{"title":"Sustainable Manufacturing of Vertical Carbon Nanotube (CNT) Arrays Inside Insulating Nanoporous Membranes Using Nickel Magnetic Nanowires (MNWs)","authors":"Roman Kolisnyk*, Morgen L. Smith, Nicholas C. A. Seaton, Michael L. Odlyzko, Olha Masiuchok, Jeanne Riga, Placidus B. Amama and Bethanie J. H. Stadler*, ","doi":"10.1021/acsanm.4c0478210.1021/acsanm.4c04782","DOIUrl":"https://doi.org/10.1021/acsanm.4c04782https://doi.org/10.1021/acsanm.4c04782","url":null,"abstract":"Carbon nanotubes (CNTs) were successfully synthesized using industrial waste gases by chemical vapor deposition inside vertically oriented nanopores of insulating membranes. Importantly, the waste products from Fischer–Tropsch synthesis were used as the carbon source rather than typical purified sources, and this recycling of carbon is important for the sustainability of our environment. Specifically in this work, vertical CNT arrays were achieved using nickel (Ni) magnetic nanowires (MNWs) catalysts that were prepared by template electrochemical deposition inside 50 μm-thick nanoporous anodized aluminum oxide (AAO). Here, the nanopore diameter (20–200 nm) and Ni MNW length (45 and 25 μm) were varied to study the impact on CNT growth characteristics. Raman spectroscopy, scanning electron microscopy, transmission electron microscopy, and field emission spectroscopy were used to characterize CNTs on Ni MNWs. For long MNWs (45 μm), the Ni catalyst was just below the AAO surface, so CNT diameters did not change appreciably with the MNW diameter. Alternatively, for short MNWs (25 μm), the carbon source gases had to diffuse into the AAO nanopores before reacting with the Ni catalyst, and both the CNT diameter and yield increased with the nanopore diameter. Highly crystalline CNTs were formed from particles of Ni catalyst, although for smaller diameter nanopores, the Ni catalyst particle could be blocked by template pore wall defects, resulting in subsequent amorphous nanofiber growth above the blocked particle. Optimally, CNT synthesis was observed for 25 μm MNWs grown in 80 nm AAO nanopores, maximizing field emission current at 480 μA/cm2 (at electric field 0.5 V/μm) with a turn-on field of 0.26 V/μm.","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":null,"pages":null},"PeriodicalIF":5.3,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142608176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tailoring of Nanomesh Arrays with Venus Flytrap-Like NiCoP/NiCo-LDH for Supercapacitors 用金星捕蝇草状 NiCoP/NiCo-LDH 为超级电容器定制纳米网格阵列

IF 5.3 2区材料科学

ACS Applied Nano Materials Pub Date : 2024-10-18 DOI: 10.1021/acsanm.4c0472910.1021/acsanm.4c04729

Lei Zhu, Yuxiang Wang, Yue Wei, Yiyu Zhu, Zijun Zuo, Yuebin Cao, Wonchun Oh*, Lele Fan* and Qinfang Zhang*,

{"title":"Tailoring of Nanomesh Arrays with Venus Flytrap-Like NiCoP/NiCo-LDH for Supercapacitors","authors":"Lei Zhu, Yuxiang Wang, Yue Wei, Yiyu Zhu, Zijun Zuo, Yuebin Cao, Wonchun Oh*, Lele Fan* and Qinfang Zhang*, ","doi":"10.1021/acsanm.4c0472910.1021/acsanm.4c04729","DOIUrl":"https://doi.org/10.1021/acsanm.4c04729https://doi.org/10.1021/acsanm.4c04729","url":null,"abstract":"The superior electrochemical functionality of supercapacitor electrodes is heavily reliant on the strategic design of nanostructures that effectively integrate diverse active materials. In this study, a facile hydrothermal method was investigated for easy synthesis of Venus flytrap-like NiCoP using nickel foam (NF) as both the substrate and the nickel source. Furthermore, the electrochemical deposition of NiCo-LDH onto the 3D NiCoP nanomeshes was delved into, creating a hybrid nanomaterial with enhanced energy storage capability of 1675 F/g (1 A/g). This innovative combination of conductive NiCoP as a core and redox-active NiCo-LDH as a shell forms a smart heteronetwork that boosts surface area, enhances the presence of the redox-active sites, and improves ion/electron transport for faradaic reactions. The NiCoP/NiCo-2//PC supercapacitor boasts a remarkable energy density of 30.96 Wh/kg and a power density of 783.90 W/kg and displays favorable capacitance retention rate characteristics (73.5%, from 600 to 10,000 cycles). This effective and simple technique for transforming a high-performance anode on a nickel foam substrate could significantly improve their applicability for large-scale use as well as provide useful knowledge for creating self-supporting substrates for energy storage and conversion through other manufacturing processes.","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":null,"pages":null},"PeriodicalIF":5.3,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142608113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pt Single Atoms and Clusters Supported on N-Doped Porous Carbon for Improved Hydrogen Evolution Reaction 掺杂 N 的多孔碳上支持的铂单原子和铂簇可改善氢气进化反应

IF 5.3 2区材料科学

ACS Applied Nano Materials Pub Date : 2024-10-18 DOI: 10.1021/acsanm.4c0487910.1021/acsanm.4c04879

Jianfei Lei*, Ying Chen, Kaijie Liu, Shenao Liu, Yang Liu, Shanteng Zhang, Jinmei Wang, Fujing Dong and Yanfei Liu,

{"title":"Pt Single Atoms and Clusters Supported on N-Doped Porous Carbon for Improved Hydrogen Evolution Reaction","authors":"Jianfei Lei*, Ying Chen, Kaijie Liu, Shenao Liu, Yang Liu, Shanteng Zhang, Jinmei Wang, Fujing Dong and Yanfei Liu, ","doi":"10.1021/acsanm.4c0487910.1021/acsanm.4c04879","DOIUrl":"https://doi.org/10.1021/acsanm.4c04879https://doi.org/10.1021/acsanm.4c04879","url":null,"abstract":"Platinum is renowned for its exceptional catalytic performance in the hydrogen evolution reaction (HER), but its high cost and rarity seriously hinder the large-scale application of platinum electrocatalysts. Constructing highly dispersed platinum active sites is an effective strategy to lower the loading of Pt while maintaining high activity. Herein, a highly dispersed Pt catalyst composed of a mixture of single atoms and clusters is synthesized on porous N-doped carbon (Pt/N-PC) derived from renewable peony. The existence of Pt single atoms and clusters was confirmed by combining methods such as aberration-corrected high-angle annular dark field-scanning transmission electron microscopy images (HAADF-STEM), X-ray absorption fine structure (XAFS), and X-ray photoelectron spectroscopy (XPS). The Pt/N-PC catalyst exhibits superior performance compared to the Pt-free catalyst (N-PC) as well as to the commercial 20 wt % Pt/C catalyst. It exhibits an overpotential of just 11 mV at a current density of 10 mA/cm2, a Tafel slope of 24.1 mV/dec, and an exceptional long-term durability in acidic environments. Notably, upon optimizing the geometric loading amount of Pt, the optimal catalyst achieves an ultrahigh platinum mass activity of 3.44 A mg–1Pt at a potential of −50 mV. This value is approximately 9.5 times greater than that of the commercial 20 wt % Pt/C catalyst (0.36 A mg–1Pt).","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":null,"pages":null},"PeriodicalIF":5.3,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bimetallic Cu@Co-MOFs Mimic Peroxidase for Colorimetric Detection of Glutathione 双金属 Cu@Co-MOFs 可模拟过氧化物酶，用于比色检测谷胱甘肽

IF 5.3 2区材料科学

ACS Applied Nano Materials Pub Date : 2024-10-17 DOI: 10.1021/acsanm.4c0456310.1021/acsanm.4c04563

Yaohua Gu, Jiping Han, Ni Zhang, Weisong Yan, Yue Guo, Huiyi Tan, Changyi Yang*, Fuke Wang* and Huiqin Yao*,

{"title":"Bimetallic Cu@Co-MOFs Mimic Peroxidase for Colorimetric Detection of Glutathione","authors":"Yaohua Gu, Jiping Han, Ni Zhang, Weisong Yan, Yue Guo, Huiyi Tan, Changyi Yang*, Fuke Wang* and Huiqin Yao*, ","doi":"10.1021/acsanm.4c0456310.1021/acsanm.4c04563","DOIUrl":"https://doi.org/10.1021/acsanm.4c04563https://doi.org/10.1021/acsanm.4c04563","url":null,"abstract":"Nanozyme possess the advantages of high enzyme simulation activity, low cost, and excellent stability. As a substitute for natural enzymes, nanozyme have demonstrated significant potential in various fields. In this study, a bimetallic organometallic framework Cu@Co-MOFs was synthesized via the hydrothermal method using terephthalic acid (H2BDC) as a ligand and characterized. Cu@Co-MOFs exhibits outstanding peroxidase activity (POD) by catalyzing the oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB) and other color-developing substrates through •OH formation. A simple, rapid, and reliable colorimetric method for quantitatively detecting glutathione (GSH) was developed based on the Pod-like activity of Cu@Co-MOFs. The linear range of this method was 1–1200 μM with a detection limit of 0.72 μM. This work not only proposes a bimetallic organic framework with high POD as a straightforward and practical platform for visually detecting GSH but also provides a strategy to enhance the performance of nanomaterials.","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":null,"pages":null},"PeriodicalIF":5.3,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142608169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Willow Catkin-like Co4S3–WS2 Nanostructured Electrocatalyst for Efficient Overall Alkaline Water Splitting 用于高效整体碱性水分离的柳树荑状 Co4S3-WS2 纳米结构电催化剂

IF 5.3 2区材料科学

ACS Applied Nano Materials Pub Date : 2024-10-17 DOI: 10.1021/acsanm.4c0400410.1021/acsanm.4c04004

Jiani Wang, Qian Ling, Yuxiang Yao, Denglin Zhu, Sizhan Shu, Zile Zhou, Xuefei Wu* and Pingfan Wu*,

{"title":"Willow Catkin-like Co4S3–WS2 Nanostructured Electrocatalyst for Efficient Overall Alkaline Water Splitting","authors":"Jiani Wang, Qian Ling, Yuxiang Yao, Denglin Zhu, Sizhan Shu, Zile Zhou, Xuefei Wu* and Pingfan Wu*, ","doi":"10.1021/acsanm.4c0400410.1021/acsanm.4c04004","DOIUrl":"https://doi.org/10.1021/acsanm.4c04004https://doi.org/10.1021/acsanm.4c04004","url":null,"abstract":"Exploring catalysts with high catalytic activity, abundant reserves, and low cost is of great significance for the hydrogen evolution reaction (HER). Polyoxometalates (POMs) have attracted extensive attention in recent years due to their rich structure and unique electrocatalytic properties. In this study, a nanostructured Co4S3–WS2 electrocatalyst was synthesized through a hydrothermal reaction using thiourea and polyoxometalate (Co5W19) as precursors. The synergistic effect between the prepared bimetallic cobalt tungsten sulfide nanomaterial (Co4S3–WS2) promoted electron transfer and improved electrocatalytic performance exhibited excellent electrocatalytic activity with lower overpotentials for hydrogen evolution and oxygen evolution reactions (OER) at 10 mA cm–2, namely, 133 mV and 297 mV, respectively, with Tafel slopes of 114 mV dec–1 and 55 mV dec–1. Additionally, the material demonstrated long-term stability during continuous electrocatalysis. The in situ growth of the Co4S3–WS2 nanomaterial on carbon cloth via hydrothermal synthesis using the POM precursor provides guidance and inspiration for designing efficient HER electrocatalysts.","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":null,"pages":null},"PeriodicalIF":5.3,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142608477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Customization of Nanogap Arrays Using Stereolithography and Nanoskiving for Surface-Enhanced Raman Scattering 利用立体光刻和纳米剥离定制用于表面增强拉曼散射的纳米间隙阵列

IF 5.3 2区材料科学

ACS Applied Nano Materials Pub Date : 2024-10-17 DOI: 10.1021/acsanm.4c0512510.1021/acsanm.4c05125

Zifan Xiao, Chong Chen, Ge Xiao, Yun Jiang, Xiaomi Lu, Yu Wang*, Bin Ai* and Gang Zhang*,

{"title":"Customization of Nanogap Arrays Using Stereolithography and Nanoskiving for Surface-Enhanced Raman Scattering","authors":"Zifan Xiao, Chong Chen, Ge Xiao, Yun Jiang, Xiaomi Lu, Yu Wang*, Bin Ai* and Gang Zhang*, ","doi":"10.1021/acsanm.4c0512510.1021/acsanm.4c05125","DOIUrl":"https://doi.org/10.1021/acsanm.4c05125https://doi.org/10.1021/acsanm.4c05125","url":null,"abstract":"Nanoskiving has been utilized in the fabrication of plasmonic nanogaps. It is imperative to develop a cost-effective and highly adjustable method for the manipulation of predetermined models, as the fabrication of nanogaps by nanoskiving relies on predetermined models. Here, a method is proposed that leverages stereolithography to design and fabricate predetermined models, coupled with nanoskiving to fabricate various patterned nanogaps for surface-enhanced Raman scattering. Four different patterned arrays (rod-shaped nanogap arrays, striped nanogap arrays, square-arranged crescent-shaped nanogap arrays, and hexagon-arranged crescent-shaped nanogap arrays) with 5 nm nanogaps are successfully fabricated. The strong plasmon coupling is excited within nanogaps, leading to a several-fold increase in Raman intensity, higher than that of structures without a nanogap. Furthermore, it is also observed that the Raman intensity varies with the morphologies of nanogap arrays. The crescent-shaped nanogap arrays exhibit a 1.8-fold higher intensity compared to that of linear-shaped nanogap arrays. Through the theoretical analysis, this phenomenon is related to the distinct oscillating propagation of light between parallel or nonparallel noble metals. The innovative combination of stereolithography and nanoskiving paves the way for the fabrication of patterned nanogaps, holding significant potential for plasmonic sensors, nonlinear optics, and molecule detection.","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":null,"pages":null},"PeriodicalIF":5.3,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142550341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Carbon-Based Nanoarchitectonics in Advancing Cardiac Tissue Bioprinting: A Review 推进心脏组织生物打印的碳基纳米结构：综述

IF 5.3 2区材料科学

ACS Applied Nano Materials Pub Date : 2024-10-17 DOI: 10.1021/acsanm.4c0444110.1021/acsanm.4c04441

Mansi Dixit, Lok Kumar Shrestha, Katsuhiko Ariga and Falguni Pati*,

{"title":"Carbon-Based Nanoarchitectonics in Advancing Cardiac Tissue Bioprinting: A Review","authors":"Mansi Dixit, Lok Kumar Shrestha, Katsuhiko Ariga and Falguni Pati*, ","doi":"10.1021/acsanm.4c0444110.1021/acsanm.4c04441","DOIUrl":"https://doi.org/10.1021/acsanm.4c04441https://doi.org/10.1021/acsanm.4c04441","url":null,"abstract":"Recent advancements in tissue engineering, particularly cardiac tissue bioprinting, have been remarkable. A pivotal aspect of these advancements is the integration of electrically conductive biomaterials, which are essential for creating functional and viable substitutes for damaged cardiac tissue. Among these materials, carbon-based nanoarchitectonics, such as graphene, carbon nanotubes (CNTs), and carbon nanofibers (CNFs), have garnered significant attention due to their exceptional electrical properties and biocompatibility. This perspective carefully explores the contemporary landscape of utilizing these carbon-based materials in cardiac tissue bioprinting, highlighting their unique properties and strong biocompatibility. Graphene, known for its single-layer carbon structure and exceptional electrical conductivity, plays a crucial role in enhancing cell communication and tissue functionality in engineered cardiac tissues. Similarly, carbon nanotubes (CNTs) and carbon nanofibers (CNFs) offer outstanding electrical conductivity and mechanical strength, making them ideal candidates for improving structural integrity and electrical signaling within bioprinted cardiac constructs. The review emphasizes how these carbon-based materials seamlessly integrate into bioinks, facilitating three-dimensional bioprinting processes to create intricate cardiac tissue structures that closely mimic native tissues. This integration not only enhances the mechanical properties of bioinks but also supports cell adhesion, proliferation, and differentiation that are crucial for developing functional cardiac tissues. Overall, the transformative impact of carbon-based materials in regenerative medicine, particularly in cardiac regeneration, underscores an era of innovation. These materials hold immense promise for advancing treatment options for heart diseases, offering potential solutions for effectively repairing and replacing damaged cardiac tissue effectively.","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":null,"pages":null},"PeriodicalIF":5.3,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142608495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tailored Porous Conductive Elastomer Composites for Highly Sensitive Flexible Pressure Sensors over a Wide Range 用于大范围高灵敏度柔性压力传感器的定制多孔导电弹性体复合材料

IF 5.3 2区材料科学

ACS Applied Nano Materials Pub Date : 2024-10-17 DOI: 10.1021/acsanm.4c0458010.1021/acsanm.4c04580

Jun Wang, Jing Lin*, Xinqing Chen, Ye Li, Kelin Pan, Kai Chen, Dechao Hu* and Jianyi Luo*,

{"title":"Tailored Porous Conductive Elastomer Composites for Highly Sensitive Flexible Pressure Sensors over a Wide Range","authors":"Jun Wang, Jing Lin*, Xinqing Chen, Ye Li, Kelin Pan, Kai Chen, Dechao Hu* and Jianyi Luo*, ","doi":"10.1021/acsanm.4c0458010.1021/acsanm.4c04580","DOIUrl":"https://doi.org/10.1021/acsanm.4c04580https://doi.org/10.1021/acsanm.4c04580","url":null,"abstract":"Developing high-performance pressure sensors with a wide detection range while retaining high sensitivity remains an enormous challenge. Herein, the porous conductive elastomer composite-based pressure sensors composed of natural rubber (NR) and multiwall carbon nanotubes (MWCNTs) were fabricated by the facile freeze-drying approach. The homogeneous dispersion of MWCNTs facilitates the formation of continuous conductive pathways within the NR matrix. When NR/MWCNTs conductive elastomer composites (CECs) were compressed, MWCNTs embedded in micropore walls can contact each other and strengthen the conductive pathways. Consequently, the as-obtained sensors exhibited a high sensitivity of 1.145 kPa–1 over 0–480 kPa, a short response–relaxation time, and an excellent reversibility and stability. In addition, the sensors can effectively detect and capture subtle and large human movements such as wrist, elbow, knee bending, and even pulse. Furthermore, the sensors can be assembled and integrated with a glove to achieve remote gesture recognition and sports training monitoring. The designed NR/MWCNTs CECs-based pressure sensors hold great promise for integration into flexible wearable electronics.","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":null,"pages":null},"PeriodicalIF":5.3,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142608329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Oxygen Nanobubbles Halt Tumor Aggression and Metastasis by Inhibiting Hypoxia-Induced Epithelial-to-Mesenchymal Transition in Lung and Mammary Adenocarcinoma 纳米氧气泡通过抑制缺氧诱导的肺癌和乳腺癌上皮细胞向间质转化阻止肿瘤侵袭和转移

IF 5.3 2区材料科学

ACS Applied Nano Materials Pub Date : 2024-10-17 DOI: 10.1021/acsanm.4c0529510.1021/acsanm.4c05295

Kumari Bhavya, Kalyani Agarwal, Deepa Negi, Karishma Niveria, Yashveer Singh, Anita Kamra Verma, Suman Dasgupta, Neelkanth Nirmalkar* and Durba Pal*,

{"title":"Oxygen Nanobubbles Halt Tumor Aggression and Metastasis by Inhibiting Hypoxia-Induced Epithelial-to-Mesenchymal Transition in Lung and Mammary Adenocarcinoma","authors":"Kumari Bhavya, Kalyani Agarwal, Deepa Negi, Karishma Niveria, Yashveer Singh, Anita Kamra Verma, Suman Dasgupta, Neelkanth Nirmalkar* and Durba Pal*, ","doi":"10.1021/acsanm.4c0529510.1021/acsanm.4c05295","DOIUrl":"https://doi.org/10.1021/acsanm.4c05295https://doi.org/10.1021/acsanm.4c05295","url":null,"abstract":"The rapid proliferation of cancer cells creates a hypoxic microenvironment in solid tumors, driving aggressiveness through epithelial-to-mesenchymal transition (EMT), invasion, and migration, often leading to resistance to conventional chemotherapies. Delivering oxygen directly to the tumor site can address these challenges. Herein, we fabricated liposomal encapsulated oxygen nanobubbles (L-ONBs) with nanoscale size that exhibit enhanced stability and efficient oxygen release. Characterization revealed that the robust stability and negative surface charge of L-ONB particles prevent aggregation and facilitate passive targeting to tumor tissues due to the enhanced permeability and retention effect, thereby significantly reducing the aggressiveness of lung and breast tumors. Oxygen nanobubbles countered the hypoxia-induced EMT pathway by facilitating prolyl hydroxylation of hypoxia-inducible factor 1α, leading to its proteasomal degradation. This process resulted in the upregulation of epithelial marker E-cadherin and the downregulation of mesenchymal markers such as N-cadherin and vimentin, along with a significant decrease in transforming growth factor-β and vascular endothelial growth factor-A. Overall, our study elucidates the cellular mechanisms by which L-ONBs inhibit hypoxia-induced tumor aggressiveness, highlighting their potential as a promising therapeutic option for managing solid tumors.","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":null,"pages":null},"PeriodicalIF":5.3,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142608328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electrothermal/Superhydrophobic Anti-Deicing Coating with a Sandwich Structure Based on Micro-Nanomaterials 基于微纳米材料的夹层结构电热/超疏水防结冰涂层

IF 5.3 2区材料科学

ACS Applied Nano Materials Pub Date : 2024-10-17 DOI: 10.1021/acsanm.4c0476810.1021/acsanm.4c04768

Ke Li, Qiang Wang, Xu Zhou, Yulong He, Yanan Shi, Mengjie Qin, Binrui Wu, Ningli Chen, Ruidi Liu* and Xian Yi*,

{"title":"Electrothermal/Superhydrophobic Anti-Deicing Coating with a Sandwich Structure Based on Micro-Nanomaterials","authors":"Ke Li, Qiang Wang, Xu Zhou, Yulong He, Yanan Shi, Mengjie Qin, Binrui Wu, Ningli Chen, Ruidi Liu* and Xian Yi*, ","doi":"10.1021/acsanm.4c0476810.1021/acsanm.4c04768","DOIUrl":"https://doi.org/10.1021/acsanm.4c04768https://doi.org/10.1021/acsanm.4c04768","url":null,"abstract":"The freezing phenomenon poses significant challenges in many fields, causing serious casualties and economic losses. Compared with traditional measures, active/passive coupled anti-deicing technology exhibits greater adaptability and effectiveness in diverse scenarios. Herein, an electrothermal/superhydrophobic coating featuring a sandwich structure was proposed for anti-deicing applications. Benefiting from the hydrophobic modified micro-nanostructure, this superhydrophobic coating boasted remarkable abilities to delay icing and repel water adhesion, rendering it ideal for combating freezing rain. Under a certain electrothermal power density, the coating could be heated quickly and evenly. Furthermore, it has proven to be highly capable of enduring prolonged continuous heating and rigorous high–low-temperature cycling tests, delivering exceptional performance. To evaluate its dynamic anti-icing performance, icing wind tunnel tests were conducted, which demonstrated that the coating can prevent freezing with the coupled electrothermal/superhydrophobic properties, even under harsh icing environments. This work would inspire the design of electrothermal/superhydrophobic anti-deicing coating with a sandwich structure and promote the practical engineering applications.","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":null,"pages":null},"PeriodicalIF":5.3,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142608643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0