ACS Applied Nano Materials最新文献_第9页

An Innovative Approach to Fabricate Wrinkled Silver-Based Nanoporous Materials for SERS Detection 一种用于SERS检测的褶皱银基纳米多孔材料的创新制备方法

IF 5.5 2区材料科学

ACS Applied Nano Materials Pub Date : 2025-09-10 DOI: 10.1021/acsanm.5c03185

Robin Dantinne, Suyog Asaram Raut, Adrien Chauvin, Carla Bittencourt, Philippe Leclère and Damien Thiry*,

{"title":"An Innovative Approach to Fabricate Wrinkled Silver-Based Nanoporous Materials for SERS Detection","authors":"Robin Dantinne, Suyog Asaram Raut, Adrien Chauvin, Carla Bittencourt, Philippe Leclère and Damien Thiry*, ","doi":"10.1021/acsanm.5c03185","DOIUrl":"https://doi.org/10.1021/acsanm.5c03185","url":null,"abstract":"Nanostructured porous surfaces exhibit remarkable properties suitable for a diverse range of applications, such as surface-enhanced Raman scattering (SERS). Nevertheless, the facile engineering of these nanoscale materials is constrained by limitations inherent in the current synthesis methodologies employed for their fabrication. In this work, we present an innovative plasma-derived technique for the fabrication of silver-based nanoporous wrinkled surfaces. First, by depositing a magnetron-sputtered Ag–Al thin film onto a liquid plasma polymer film (PPF), we exploit the spontaneous wrinkling phenomenon that occurs in bilayer systems composed of a soft and stiff layer. Notably, the thickness of the PPF influences the nanowrinkle amplitude (ranging from 280 to 520 nm) while the wavelength remains constant (approximately 2 μm). This behavior is attributed to the pinning of the metal layer onto the silicon substrate. Then, the wrinkled surface is further nanostructured by dealloying, which involves etching of the less noble element of the alloy, here aluminum, resulting in the formation of a silver-based nanoporous structure that retains the wrinkled morphology. An increase in dealloying time, while increasing the nanopore dimensions, results in a loss of wrinkle amplitude, which can be explained by the shrinking of the metal layer during the dealloying process, leading to tensile strain. Our results clearly demonstrate the attractiveness of this innovative method for fabricating wrinkled nanoporous materials with customizable dimensions. Furthermore, this substrate applicative potential as a SERS platform has been evaluated considering the rhodamine B molecule, demonstrating a detection limit of 10–9 M.","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 37","pages":"18008–18017"},"PeriodicalIF":5.5,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145094427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multilayered Cu-Carbon Nanotube Composites for Advanced Conductors 先进导体用多层铜碳纳米管复合材料

IF 5.5 2区材料科学

ACS Applied Nano Materials Pub Date : 2025-09-10 DOI: 10.1021/acsanm.5c03028

Kai Li, Huixin Jiang, Michael McGuire, Mina Yoon, Andrew Lupini, Fred A. List, Christopher C. Bowland, Amit Naskar, Mariappan Parans Paranthaman, Kashif Nawaz, Edgar Lara-Curzio, James A. Haynes and Tolga Aytug*,

{"title":"Multilayered Cu-Carbon Nanotube Composites for Advanced Conductors","authors":"Kai Li, Huixin Jiang, Michael McGuire, Mina Yoon, Andrew Lupini, Fred A. List, Christopher C. Bowland, Amit Naskar, Mariappan Parans Paranthaman, Kashif Nawaz, Edgar Lara-Curzio, James A. Haynes and Tolga Aytug*, ","doi":"10.1021/acsanm.5c03028","DOIUrl":"https://doi.org/10.1021/acsanm.5c03028","url":null,"abstract":"Improving the efficiency of electrical components is critical in reducing energy consumption for various industrial and residential applications, ranging from rotating machinery to all electric devices and electric vehicle (EV) components to power grid systems. Substituting Cu wires with reduced resistance conductors that incorporate carbon nanotubes (CNTs) into Cu─ultraconductive Cu (UCC) composites─has recently been considered a promising strategy to improve energy efficiency, power density, and/or performance across various applications. In this study, we created stable material formulations [CNT-containing polyvinylpyrrolidone (PVP) in dimethylformamide (DMF) solution] and utilized commercially viable fabrication approaches (electrospinning and magnetron sputtering) that produced high-performance multilayered tape-based UCC composite architectures. Increasing the CNT volume fraction by sequential layering of the structure with additional Cu-CNT layers showed a nearly stepwise improved performance in electrical and mechanical properties. This study also provides valuable insight into the effectiveness of nitrogen doping in modifying the conductivity of the CNT matrix. Fabricated prototypes demonstrated a >10% increase in current carrying capacity and >10% improvement in mechanical strength compared to those obtained on pure Cu. We believe that the properties demonstrated here, combined with the scalable manufacturing pathway of our approach, pave the way in designing future advanced conductors for diverse energy efficient and high-performance electrical systems and applications.","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 37","pages":"17986–17993"},"PeriodicalIF":5.5,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145094455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bimetallic Transition Metal@Au Core–Shell Nanocatalysts for Enhanced Heterogeneous Fenton-Like Reactions: A Theoretical Study 双金属过渡Metal@Au增强非均相类芬顿反应的核壳纳米催化剂：理论研究

IF 5.5 2区材料科学

ACS Applied Nano Materials Pub Date : 2025-09-10 DOI: 10.1021/acsanm.5c03453

Mingjie Wu, Zhenhui Xu, Qiang Liu, Xiuli Hou*, Yichan Li and Peng Zhang*,

{"title":"Bimetallic Transition Metal@Au Core–Shell Nanocatalysts for Enhanced Heterogeneous Fenton-Like Reactions: A Theoretical Study","authors":"Mingjie Wu, Zhenhui Xu, Qiang Liu, Xiuli Hou*, Yichan Li and Peng Zhang*, ","doi":"10.1021/acsanm.5c03453","DOIUrl":"https://doi.org/10.1021/acsanm.5c03453","url":null,"abstract":"Gold-based core–shell catalysts for Fenton-like reactions have attracted significant attention in chemodynamic therapy. Nevertheless, their rational design remains challenging due to poorly understood structure–performance relationships. Combining density functional theory with machine learning, this work established a general design principle for bimetallic core–shell nanoparticles with a superior H2O2 dissociation performance. Incorporating a secondary transition metal as the core can optimize the electronic distribution of the Au shell, modulate adsorption strength of reaction intermediates, and thereby enhance catalytic performance. The catalytic activity for H2O2 dissociation on M@Au (M denotes Mn, Ni, Cu, Mo, Ru, Rh, Pd, Ag, Re, Ir, and Pt) core–shell clusters exhibits a volcano-shaped relationship with the adsorption strength. Benefiting from synergistic bimetallic effects, Ru@Au, Os@Au, and Cu@Au exhibit significantly enhanced performance compared to the pristine Au counterpart. Furthermore, one energetic and two structural descriptors were constructed, which quantitatively link inherent catalyst properties to catalytic performance. This work can offer a fundamental framework for advancing Fenton-like catalysts.","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 37","pages":"18147–18155"},"PeriodicalIF":5.5,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145094458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spark Ablation-Generated Nanoparticles on Filter Paper: A 3D SERS Platform for Cost-Effective and Rapid Thiram Sensing 火花烧蚀在滤纸上产生的纳米颗粒：一种具有成本效益和快速Thiram传感的3D SERS平台

IF 5.5 2区材料科学

ACS Applied Nano Materials Pub Date : 2025-09-10 DOI: 10.1021/acsanm.5c02891

Viktória Horváth*, Dániel Megyeri, Judit Kopniczky, Maher Darwish, Zsolt Geretovszky and Attila Kohut,

{"title":"Spark Ablation-Generated Nanoparticles on Filter Paper: A 3D SERS Platform for Cost-Effective and Rapid Thiram Sensing","authors":"Viktória Horváth*, Dániel Megyeri, Judit Kopniczky, Maher Darwish, Zsolt Geretovszky and Attila Kohut, ","doi":"10.1021/acsanm.5c02891","DOIUrl":"https://doi.org/10.1021/acsanm.5c02891","url":null,"abstract":"Surface-enhanced Raman spectroscopy (SERS) is a highly specific technique for identifying the contents of an unknown sample. It is based on the plasmonic enhancement provided by a nanostructured surface called a SERS substrate. The enhancement is heavily influenced by the geometric features of the substrate, which can be manipulated through the fabrication of the nanostructure. Here, we propose a fabrication method that uses nanoparticles synthesized in the gas phase through spark ablation; the generated particles are deposited onto filter papers, forming 3D SERS active nanostructures along the depth of the filter. The SERS properties of the structure can be tuned through the configuration of the experimental properties: we present how the spark frequency and the compaction temperature can be used to affect the size and shape of the generated nanoparticles and how the choice of filter affects the overall SERS enhancement. The fabricated SERS substrates were then used to detect a widely used pesticide: thiram. Using our substrates, the direct detection of 1.2 ppm thiram was feasible. We also proposed a deep-learning-based scheme, with which even lower concentrations─in between 0.03 and 0.48 ppm─could be distinguished, with an accuracy of 94.44%.","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 37","pages":"17934–17951"},"PeriodicalIF":5.5,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acsanm.5c02891","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145094422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Patterned Silver Nanowire Networks in UV-Curable Polymers for Flexible Blue Quantum Dot Light-Emitting Diode Electrodes 柔性蓝量子点发光二极管电极中紫外光固化聚合物的图案银纳米线网络

IF 5.5 2区材料科学

ACS Applied Nano Materials Pub Date : 2025-09-10 DOI: 10.1021/acsanm.5c03478

Tsai-Ti Tung, Yi-Lun Jain, Arjun G. Ansay, Meng-Chu Chen* and Chun-Yuan Huang*,

{"title":"Patterned Silver Nanowire Networks in UV-Curable Polymers for Flexible Blue Quantum Dot Light-Emitting Diode Electrodes","authors":"Tsai-Ti Tung, Yi-Lun Jain, Arjun G. Ansay, Meng-Chu Chen* and Chun-Yuan Huang*, ","doi":"10.1021/acsanm.5c03478","DOIUrl":"https://doi.org/10.1021/acsanm.5c03478","url":null,"abstract":"In this study, the patterned silver nanowire network (PSNN) with low surface roughness embedded in the surface of UV-curable polymer (NOA63) was demonstrated. To overcome the inherent limitations of silver nanowires for use in flexible electrodes, several effective strategies were sequentially implemented. First, UV-ozone treatment was applied to the glass/PMMA substrate to selectively create hydrophilic regions for precise electrode patterning. Second, to reduce wire-to-wire junction resistance without compromising electrode transparency, a simple capillary-force-induced cold-welding process was employed. Finally, electrode planarization was achieved by peeling the NOA63/PSNN film from the glass substrate. Specifically, the nanowire network in NOA63 exhibited a sheet resistance of 28 ± 6 Ω/sq and an exceptional transparency of 86.6% at 474 nm, outperforming commercially available ITO on PET substrates (37 Ω/sq, 82.3%). Furthermore, the NOA63/PSNN substrate demonstrated excellent adhesion strength, air stability, and bending durability. Finally, blue quantum dot light-emitting diodes (QLEDs) fabricated on the NOA63/PSNN substrates showed a low turn-on voltage of 3.2 V, a maximum luminance of 7733 cd/m2, and a maximum current efficiency of 4.5 cd/A, indicating that our flexible NOA63/PSNN substrate strategy is highly promising and cost-effective for blue-light-based optoelectronic applications.","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 37","pages":"18166–18173"},"PeriodicalIF":5.5,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acsanm.5c03478","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145094428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

3D Graphene-like Microstructures for Multi-Frequency Wide-Angle Terahertz Absorption 多频广角太赫兹吸收的三维类石墨烯微结构

IF 5.5 2区材料科学

ACS Applied Nano Materials Pub Date : 2025-09-10 DOI: 10.1021/acsanm.5c03057

Donghui Huang, Kaixi Bi*, Liuyu Hou, Guangchen Yin, Longhao Liu, Hao Liu, Wenqi Xiong, Jialiang Chen and Linyu Mei*,

{"title":"3D Graphene-like Microstructures for Multi-Frequency Wide-Angle Terahertz Absorption","authors":"Donghui Huang, Kaixi Bi*, Liuyu Hou, Guangchen Yin, Longhao Liu, Hao Liu, Wenqi Xiong, Jialiang Chen and Linyu Mei*, ","doi":"10.1021/acsanm.5c03057","DOIUrl":"https://doi.org/10.1021/acsanm.5c03057","url":null,"abstract":"Three-dimensional (3D) graphene-like microstructures have great potential for terahertz (THz) absorbers, owing to their high electrical conductivity, strong dielectric loss, and unique microstructure. Photosensitive polyimide (PSPI) organic films were commonly used to construct high aspect ratio micrometer structure, and its characteristic size is close to the terahertz wavelength, which is suitable for the development of terahertz absorption devices. In this work, optical lithography and electron beam lithography were combined to induce graphitized carbon films on the surface of PSPI array structure, forming the wafer-level graphene-like/Si/Au sandwich absorber. The test results show that the absorption peaks are located at 0.29 THz, 0.49 THz, 0.70 THz, 0.91 THz, 1.12 THz, 1.32 THz, 1.53 THz, and the absorptions are over 90%. The maximum absorption intensity is close to 99%. Meanwhile, the absorber exhibited outstanding structure insensitivity and wide-angle absorption characteristics across varying structural parameters, size ratios, and incident angles (0–60°). In addition, we further analyzed the absorption properties of the device by varying the thickness of the dielectric layer (50–200 μm), aiming to determine the correlation between the resonant frequency of the absorber and the thickness of the dielectric layer. These results may provide an effective concept and fabrication technique to stimulate many potential applications in emerging terahertz technologies, such as sensing, imaging, and wireless communications.","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 37","pages":"17968–17976"},"PeriodicalIF":5.5,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145094457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Large-Period van der Waals Epitaxy of Au on MoS2 at Room Temperature: Moiré-Engineered Interfaces for Nanoelectronics 室温下金在二硫化钼上的大周期范德华外延：纳米电子学的莫伊兰工程界面

IF 5.5 2区材料科学

ACS Applied Nano Materials Pub Date : 2025-09-10 DOI: 10.1021/acsanm.5c03991

Yu-Che Huang, Liang-Ching He, Kuan-Yu Yeh, Kuan-Bo Lin, Hui-Ting Liu, Shang-Jui Chiu, Yan-Gu Lin, Yi-Wei Tsai, Jhih-Min Lin, Sen-Hao Chang, Tsung-Mu Wu, Kris Ke-Hsien Lin, Shin-Yuan Wang, Chao-Hsin Chien, Chun-Liang Lin, Shu-Jui Chang*, Edward Yi Chang* and Chenming Hu*,

{"title":"Large-Period van der Waals Epitaxy of Au on MoS2 at Room Temperature: Moiré-Engineered Interfaces for Nanoelectronics","authors":"Yu-Che Huang, Liang-Ching He, Kuan-Yu Yeh, Kuan-Bo Lin, Hui-Ting Liu, Shang-Jui Chiu, Yan-Gu Lin, Yi-Wei Tsai, Jhih-Min Lin, Sen-Hao Chang, Tsung-Mu Wu, Kris Ke-Hsien Lin, Shin-Yuan Wang, Chao-Hsin Chien, Chun-Liang Lin, Shu-Jui Chang*, Edward Yi Chang* and Chenming Hu*, ","doi":"10.1021/acsanm.5c03991","DOIUrl":"https://doi.org/10.1021/acsanm.5c03991","url":null,"abstract":"The continuous miniaturization of integrated circuits has driven interest in two-dimensional (2D) transition metal dichalcogenides (TMDs) as atomically thin semiconductors with exceptional electronic properties and substrate compatibility. In this study, we investigate the room temperature epitaxial growth of ultrathin gold (Au) films on monolayer molybdenum disulfide (MoS2), focusing on the nanoscale structural evolution at the metal–TMD interface. In the initial stages of Au epitaxy, epitaxial Au grains and MoS2 appear as moiré patterns with varying orientations. As growth progresses, these patterns converge into a dominant (12Au–11MoS2) moiré pattern, forming a continuous epitaxial Au film with a lattice mismatch of only 0.6% with MoS2. Analysis of the Au/MoS2 interface reveals that large-period epitaxy induces an ∼0.6° tilt in the Au crystal planes. Density functional theory (DFT) calculations further demonstrate how local interfacial modifications contribute to lattice misalignment and strain distribution. These results provide atomic-scale insight into the strain accommodation and crystalline alignment mechanisms at 3D/2D interfaces, highlighting how low-temperature metal epitaxy on 2D semiconductors can enable structurally coherent and cleaner interfaces. This approach offers a promising pathway for engineering low-resistance metal contacts in next-generation nanoscale transistors and other 2D semiconductor-based devices.","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 37","pages":"18208–18215"},"PeriodicalIF":5.5,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acsanm.5c03991","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145094425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Magnetic UiO-66-NO2 Nanocomposite for Highly Efficient Adsorption and Detection of Sugar Phosphates in Biological Samples 磁性UiO-66-NO2纳米复合材料对生物样品中磷酸糖的高效吸附和检测

IF 5.5 2区材料科学

ACS Applied Nano Materials Pub Date : 2025-09-09 DOI: 10.1021/acsanm.5c03271

Zixu Wang, Linna Han, Qing Xia, Wanfang Feng, Songtao Li* and Liyan Liu*,

{"title":"Magnetic UiO-66-NO2 Nanocomposite for Highly Efficient Adsorption and Detection of Sugar Phosphates in Biological Samples","authors":"Zixu Wang, Linna Han, Qing Xia, Wanfang Feng, Songtao Li* and Liyan Liu*, ","doi":"10.1021/acsanm.5c03271","DOIUrl":"https://doi.org/10.1021/acsanm.5c03271","url":null,"abstract":"Enrichment and quantification of sugar phosphates (SPx) in biological samples are of great significance in biological medicine. In this work, a magnetic nanoscale metal–organic framework composite, Fe3O4@UiO-66-NO2, was synthesized and utilized as a high-capacity adsorbent for the enrichment of SPx in biological samples. Fe3O4@UiO-66-NO2 exhibited a high specific surface area (310.02 m2/g), a suitable pore size (3.47 nm), and strong magnetism (14.99 emu/g), enabling convenient separation and recovery. Experimental results demonstrated that Fe3O4@UiO-66-NO2 exhibited excellent adsorption performance for five types of SPx, achieving complete adsorption within 6 min at a dosage of 200 μg, and the adsorption process exhibited pH tolerance. The adsorption isotherm result indicated that the maximum adsorption capacities for different SPx ranged from 234.06 mg/g to 403.24 mg/g. Adsorption mechanisms using X-ray photoelectron spectroscopy, FT-IR, and density functional theory revealed multiple interactions, such as coordination and hydrogen bonding, and contributed to the adsorption process. A magnetic nanoscale-dispersive solid-phase extraction protocol was developed based on a Fe3O4@UiO-66-NO2 for rapidly enriching SPx from biological samples. The protocol allowed for SPx detection over a wide linear concentration range, low limits of detection (0.001–0.02 ng/mL), high precision (<7.88%), and good accuracy (82.56%–119.66%). This protocol was successfully applied to real blood samples, prefiguring the great potential of magnetic MOFs for the enrichment and detection of SPx in biological samples.","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 37","pages":"18098–18114"},"PeriodicalIF":5.5,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145094711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fluorescence Probe for the Detection of Programmed Death-Ligand 1 (PD-L1) Using Antibody-Conjugated Silver Nanoclusters and MnO2 Nanosheets 利用抗体共轭银纳米团簇和二氧化锰纳米片的荧光探针检测程序性死亡配体1 （PD-L1）

IF 5.5 2区材料科学

ACS Applied Nano Materials Pub Date : 2025-09-09 DOI: 10.1021/acsanm.5c03443

Geneva Indongo, Merin K. Abraham, Greeshma Rajeevan, Arathy B. Kala, Dheyaa Mohammed Dhahir and Dr Sony George*,

{"title":"Fluorescence Probe for the Detection of Programmed Death-Ligand 1 (PD-L1) Using Antibody-Conjugated Silver Nanoclusters and MnO2 Nanosheets","authors":"Geneva Indongo, Merin K. Abraham, Greeshma Rajeevan, Arathy B. Kala, Dheyaa Mohammed Dhahir and Dr Sony George*, ","doi":"10.1021/acsanm.5c03443","DOIUrl":"https://doi.org/10.1021/acsanm.5c03443","url":null,"abstract":"In this study, a dual-mode fluorescence sensing platform was developed for the ultrasensitive and noninvasive detection of programmed death-ligand 1 (PD-L1), an important biomarker in cancer immunotherapy. The system integrates antibody-conjugated bovine serum albumin-stabilized silver nanoclusters (PD-L1 Ab@AgNCs) with manganese dioxide (MnO2) nanosheets as an effective quencher. The bioconjugate exhibits red fluorescence with a quantum yield of 1.85%. MnO2 nanosheets possess a high surface area and strong absorbance within the excitation and emission range of AgNCs, enabling fluorescence quenching through both the inner filter effect (IFE) and Förster resonance energy transfer (FRET), with an energy transfer efficiency of 62.7%. Upon PD-L1 recognition, the fluorescence is selectively restored due to displacement of MnO2, resulting in a turn-on signal proportional to the target concentration. The probe achieved a limit of detection of 0.44 pg/mL and a linear range of 1.98–196.78 pg/mL. The probe maintained accuracy in complex biological matrices, including saliva, serum and urine, with recovery values ranging from 96% to 108%. High specificity was confirmed by minimal interference from coexisting biomolecules. This approach offers a robust, label-free and noninvasive method for PD-L1 detection with potential for clinical diagnostics and point-of-care applications.","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 37","pages":"18156–18165"},"PeriodicalIF":5.5,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145094718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Defect Remediation of MXene Membranes Facilitated by Intercalation and Coordination Processes for Enhanced Organic Pollutant Removal 嵌入和配位过程促进MXene膜缺陷修复以增强有机污染物去除

IF 5.5 2区材料科学

ACS Applied Nano Materials Pub Date : 2025-09-09 DOI: 10.1021/acsanm.5c03186

Ming Qiu*, Yuan Wang, Yanan Liu and Zhangfeng Shen,

{"title":"Defect Remediation of MXene Membranes Facilitated by Intercalation and Coordination Processes for Enhanced Organic Pollutant Removal","authors":"Ming Qiu*, Yuan Wang, Yanan Liu and Zhangfeng Shen, ","doi":"10.1021/acsanm.5c03186","DOIUrl":"https://doi.org/10.1021/acsanm.5c03186","url":null,"abstract":"Two-dimensional (2D) materials, especially titanium carbide (Ti3C2Tx) MXene, have emerged as an ideal building block to prepare 2D membranes for water treatment. However, the prepared MXene membranes suffer from stability problems, including horizontal and vertical defects, caused by the nonuniform stacking during the preparation process and the swelling of nanosheets in water. Here, we report the design and fabrication of stable MXene membranes via an intercalation and interfacial cross-linking strategy using phytic acid (PA) and Fe3+. PA molecules act as spacer sequences to enlarge the size and stabilize the nanochannels, following coordination with Fe3+ to form a coating to cover the defects. The optimized MFP2 membrane displays outstanding water permeability at 115.9 L m–2 h–1 bar–1 (2.5 times improved compared with the MXene membrane) and good selectivity (methyl blue rejection rate: ∼99.8%; Na2SO4 rejection rate: <10.0%). Furthermore, the modified membrane shows excellent stability and antifouling performance. This study presents an environmentally friendly and straightforward approach to address the stability issue of MXene-based membranes, providing insights for the design of the next generation of high-performance membranes.","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 37","pages":"18070–18079"},"PeriodicalIF":5.5,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145094665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0