行为与脑科学期刊(英文)最新文献_第5页

TREFACE: A New Computerized Test of Emotional Stroop with Facial Expressions TREFACE:一种新的计算机化的面部表情情感测试

行为与脑科学期刊(英文) Pub Date : 2022-01-01 DOI: 10.4236/jbbs.2022.127020

E. Prada, C. Satler, M. Tavares, Ana Garcia, Lía Martínez, C. Alves, E. Lacerda, C. Tomaz

{"title":"TREFACE: A New Computerized Test of Emotional Stroop with Facial Expressions","authors":"E. Prada, C. Satler, M. Tavares, Ana Garcia, Lía Martínez, C. Alves, E. Lacerda, C. Tomaz","doi":"10.4236/jbbs.2022.127020","DOIUrl":"https://doi.org/10.4236/jbbs.2022.127020","url":null,"abstract":"Using the conflict principle of the Stroop task, “effect of interference in color naming”, the present study proposes to create a computational version of the emotional Stroop task, called TREFACE, for its acronyms in Portuguese “Teste de Reconhecimento de Expressões Faciais com Conflito Emocional” (Facial Expression Recognition Test with Emotional Conflict). In this protocol, four fixed styles of presentation were generated according to the condition: Congruent Word Reading, Incongruent Word Reading, Congruent Recognition of Face Expression and Incongruent Recognition of Face Expression, counterbalanced in terms of each facial expression, word and gender of the photo charac-ter. Forty-two healthy volunteers completed the task. Results revealed that a task associated with word reading allows better performance than a task associated with face recognition. It was also identified that in the congruent condition, there is an advantage in terms of the correct responses. Additionally, the data regarding recognition of face expression showed greater difficulty when the image was not congruent with the word. In general, the results suggest that the emotional attribute can compromise the ability to recognize the faces, reaching the functioning of mechanisms such as cognitive control and regulation of emotions. Thus, the TREFACE paradigm can be considered a good assessment tool for monitoring emotional conflict, in addition to presenting itself as a new instrument in Portuguese language for assessing emotional working memory in healthy individuals and, eventually, in different pathologies that affect the functioning of cortical areas related to executive functions.","PeriodicalId":69804,"journal":{"name":"行为与脑科学期刊(英文)","volume":"715 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70838799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Advances in Depression and Brain-Derived Neurotrophic Factor 抑郁症与脑源性神经营养因子研究进展

行为与脑科学期刊(英文) Pub Date : 2022-01-01 DOI: 10.4236/jbbs.2022.126018

Hongbiao Lin, Kunmei Wu, Xinguang Zhang, xingjie huang, Chongcai Wu, Haixiang Cai

引用次数: 0

A Preliminary Study on the Effect Evaluation of Electroacupuncture Combined with Balloon Dilation in the Treatment of Dysphagia after Cerebral Infarction 电针联合球囊扩张治疗脑梗死后吞咽困难疗效评价的初步研究

行为与脑科学期刊(英文) Pub Date : 2022-01-01 DOI: 10.4236/jbbs.2022.125013

Manping Song, Lanlan Liu, B. Feng, Jingjing Chen, Yang Yang

引用次数: 1

The Differing Effects of Nociception and Pain Memory on Pain Thresholds in Participants with and without a History of Injury: A Pretest-Posttest Quasi Experimental Study 伤害感觉和疼痛记忆对有和无损伤史受试者疼痛阈值的不同影响:一项前测后准实验研究

行为与脑科学期刊(英文) Pub Date : 2022-01-01 DOI: 10.4236/jbbs.2022.128021

D. Sueki, K. Dunleavy, E. Puentedura, Lindsey Heard, P. Heide, Ming-Shun S Cheng

引用次数: 2

The Role of EEG in the Diagnosis and Management of Patients with Sleep Disorders 脑电图在睡眠障碍患者诊断和治疗中的作用

行为与脑科学期刊(英文) Pub Date : 2021-09-30 DOI: 10.4236/jbbs.2021.1110021

Ramina Behzad, Aida Behzad

引用次数: 4

Dura Mater: Anatomy and Clinical Implication Dura Mater的解剖学及其临床意义

行为与脑科学期刊(英文) Pub Date : 2021-09-30 DOI: 10.4236/jbbs.2021.1110019

M. Ünal, Ahmet Sezgin

引用次数: 0

Experimental Study on the Effect of Acupuncture on ERM/PI3/Akt Signal Pathway in Rats with Ischemic Stroke 针刺对缺血性脑卒中大鼠ERM/PI3/Akt信号通路影响的实验研究

行为与脑科学期刊(英文) Pub Date : 2021-09-30 DOI: 10.4236/jbbs.2021.1110020

X. Bai, Ximei Xie, Ya-jun Shen, H. Bai, Yuan-Wei Tang, X. Chang, Qiuyu Li

{"title":"Experimental Study on the Effect of Acupuncture on ERM/PI3/Akt Signal Pathway in Rats with Ischemic Stroke","authors":"X. Bai, Ximei Xie, Ya-jun Shen, H. Bai, Yuan-Wei Tang, X. Chang, Qiuyu Li","doi":"10.4236/jbbs.2021.1110020","DOIUrl":"https://doi.org/10.4236/jbbs.2021.1110020","url":null,"abstract":"Objective: To observe the effect of acupuncture on the expression of ERM/PI3K/Akt signaling pathway in the brain tissue around the infarct focus of ischemic stroke model rats. Methods: According to the block randomization method, 80 male SD rats were divided into normal group (n = 10), sham operation group (n = 24), model group (n = 23) and acupuncture group (n = 23). The normal group was bred routinely without any intervention. In the sham operation group, only the skin was cut to find and the nerves and blood vessels were stripped and sutured. The model group and the acupuncture group were sutured to prepare the MCAO model. After the model was successfully established, acupuncture of the acupuncture group rats was given once a day, and the needles were kept for 30 minutes each time. The rats in the sham operation group and the model group only imitated capture and return, and were treated with acupuncture for 2 consecutive courses, each course was 5 days, and the two courses were rested for 2 days. After that, Western blot was used to detect ERM, changes in the concentration of PI3K and Akt proteins. Results: Compared with the normal group, the expression levels of ERM, PI3K, and Akt proteins in the sham operation group were reduced. Compared with the sham operation group, the expression levels of ERM, PI3K, and Akt proteins in the model group were significantly down-regulated. Compared with the model group, the protein expression levels of ERM, PI3K and Akt were significantly up-regulated in the acupuncture group, and the difference was statistically significant (P < 0.05). Conclusion: Acupuncture can significantly up-regulate the expression of ERM, PI3K and Akt proteins, and its effect mechanism may be related to the transduction of ERM/PI3K/Akt signaling pathway in cells.","PeriodicalId":69804,"journal":{"name":"行为与脑科学期刊(英文)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46972089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

The Diagnostic Value of Metagenomic Next-Generation Sequencing in Angiostrongylus cantonensis Encephalitis/Meningitis 宏基因组下一代测序对广州管圆线虫脑炎/脑膜炎的诊断价值

行为与脑科学期刊(英文) Pub Date : 2021-09-07 DOI: 10.4236/jbbs.2021.119017

Xiaowei Fan, Qiang Wang, Peiqing Li, Bin Ai, Yongling Song, Qiu-ying Peng, Hongli Wang

{"title":"The Diagnostic Value of Metagenomic Next-Generation Sequencing in Angiostrongylus cantonensis Encephalitis/Meningitis","authors":"Xiaowei Fan, Qiang Wang, Peiqing Li, Bin Ai, Yongling Song, Qiu-ying Peng, Hongli Wang","doi":"10.4236/jbbs.2021.119017","DOIUrl":"https://doi.org/10.4236/jbbs.2021.119017","url":null,"abstract":"Objective: Angiostrongylus cantonensis (A. cantonensis) is an important parasite, which causes neurological infection in children, and is generally difficult to diagnose. We analyzed the significance of metagenomic next-generation sequencing in diagnosing A. cantonensis encephalitis/meningitis in children to provide a reference for clinical diagnosis. Methods: The case collection of A. cantonensis encephalitis/meningitis was from July 2018 to August 2020. The patients’ clinical characteristics and pathogen were described, and diagnostic sensitivity methods for A. cantonensis encephalitis/meningitis were compared and analyzed, including parasite antibody detection and metagenomic next-generation sequencing (mNGS) detection in different samples. Results: Eleven cases were diagnosed with A. cantonensis encephalitis/meningitis, including six males (54.5%) and five females (45.5%), and the age ranged from 1 to 13 years with a median of 21 months (IQR: 15.6, 96). All patients were undiagnosed upon admission, of which ten cases had neurological symptoms or signs, six cases (54.5%) had a history of definite or suspicious exposure to parasites, and eight cases (72.7%) had abnormal changes in cranial MRI. The results of A. cantonensis antibodies in the peripheral blood and cerebrospinal fluid (CSF) were compared with CSF’s metagenomic next-generation sequencing (mNGS). The antibody-positive rate of peripheral blood was 54.5%, CSF antibody-positive rate was 27.2%, and mNGS-positive rate of CSF was 81.8%, and the positive diagnostic rate of the latter was significantly higher than the former two (p = 0.035 p = 0.030 Conclusion: Metagenomic next-generation sequencing has a higher positive rate for diagnosing infection and plays an important role in clarifying diagnosis and reducing misdiagnosis.","PeriodicalId":69804,"journal":{"name":"行为与脑科学期刊(英文)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42508785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

A Functional Inhibitory Role of Habenular Glucagon-Like Peptide-1 (GLP-1) in Forebrain Reward Signaling Habenular Glucagon-Like Peptide-1 (GLP-1)在前脑奖赏信号传导中的功能抑制作用

行为与脑科学期刊(英文) Pub Date : 2021-09-07 DOI: 10.4236/jbbs.2021.119016

Max Johnson, Alev M Brigande, Jiahe Yue, K. Colvin, Olivia Dao, P. Currie

{"title":"A Functional Inhibitory Role of Habenular Glucagon-Like Peptide-1 (GLP-1) in Forebrain Reward Signaling","authors":"Max Johnson, Alev M Brigande, Jiahe Yue, K. Colvin, Olivia Dao, P. Currie","doi":"10.4236/jbbs.2021.119016","DOIUrl":"https://doi.org/10.4236/jbbs.2021.119016","url":null,"abstract":"There is emerging evidence implicating glucagon-like peptide-1 (GLP-1) in reward, including palatable food reinforcement and alcohol-based reward circuitry. While recent findings suggest that mesolimbic structures, such as the ventral tegmental area (VTA) and the nucleus accumbens (NAc), are critical anatomical sites mediating the role of GLP-1’s inhibitory actions, the present study focused on the potential novel impact of GLP-1 within the habenula, a region of the forebrain expressing GLP-1 receptors. Given that the habenula has also been implicated in the neural control of reward and reinforcement, we hypothesized that this brain region, like the VTA and NAc, might mediate the anhedonic effects of GLP-1. Rats were stereotaxically implanted with guide cannula targeting the habenula and trained on a progressive ratio 3 (PR3) schedule of reinforcement. Separate rats were trained on an alcohol two-bottle choice paradigm with intermittent access. The GLP-1 agonist exendin-4 (Ex-4) was administered directly into the habenula to determine the effects on operant responding for palatable food as well as alcohol intake. Our results indicated that Ex-4 reliably suppressed PR3 responding and that this effect was dose-dependent. A similar suppressive effect on alcohol consumption was observed. These findings provide initial and compelling evidence that the habenula may mediate the inhibitory action of GLP-1 on reward, including operant and drug reward. Our findings further suggest that GLP-1 receptor mechanisms outside of the midbrain and ventral striatum are critically involved in brain reward neurotransmission.","PeriodicalId":69804,"journal":{"name":"行为与脑科学期刊(英文)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47434575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

A Model of How Matter Produces Qualitative Perception 物质如何产生定性知觉的模型

行为与脑科学期刊(英文) Pub Date : 2021-08-16 DOI: 10.4236/jbbs.2021.118013

Eric Bond

引用次数: 0