人体生理学杂志(英文)最新文献

{"title":"Low Intensity Microwave Fields and Radiation and Their Interaction with the Human Body","authors":"O. Yanenko, K. Shevchenko, S. Peregudov, V. Malanchuk","doi":"10.30564/jhp.v3i2.4160","DOIUrl":"https://doi.org/10.30564/jhp.v3i2.4160","url":null,"abstract":"Sources of low-intensity microwave signals formation, which affect the metabolism processes when they interact with human body, are considered in the article. It’s noticed that increasing intensity level of the technogenic signals in environment significantly exceeds natural electromagnetic fields and radiation (EMR). The peculiarities of the registration and measurement of low-intensity signals parameters of the microwave range are considered. The processes of the interaction of the microwave signals and human organism are analyzed. Formation mechanisms of the positive and negative microwave flows of the electromagnetic radiation are revealed. Particularly, possible formation mechanism of the microwave EMR fluxes of implants in the human body. The results of the experimental study of the EMR signals levels of the objects contacting with human body, partly materials for bone defects replacement and soft tissues regeneration so as materials for physiotherapy, are given. The use of the term “electromagnetic compatibility” for materials which contacting the human body, is proposed. The expediency of its use is proven. Microwave properties of materials for clothes, minerals and building materials, which can affect the human body and environment, have been also studied.","PeriodicalId":69096,"journal":{"name":"人体生理学杂志(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46410950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Gulf Stream and the Californian Current as Factors Affecting the Behavior and Health of Americans","authors":"Y. Pivovarenko","doi":"10.30564/jhp.v3i2.4177","DOIUrl":"https://doi.org/10.30564/jhp.v3i2.4177","url":null,"abstract":"Due to the existence of the Earth's geomagnetic field, Lorentz’s forces constantly act on all sea currents. These forces distribute the charges of sea currents in both vertical and horizontal directions. In particular, this distribution manifests itself in the electric polarization of sea currents in directions perpendicular to them. So, earlier it was shown that the same Lorentz forces cause negative electrization of the Sargasso Sea. It is also shown here that the positive electrization of the western edge of the Gulf Stream and, consequently, the eastern coast of the United States is also caused by the Lorentz force arising from the interaction of this sea current with the vertical component of the geomagnetic field. It is also shown here that the positive electrization of east edge of California Current together with west coast of USA is also caused due to the similar reasons. All this allows us to conclude that an increased concentration of positive air ions is constantly retained in the air both in the east and in the west of the United States. This situation has caused the need for an analysis of how the predominantly positive electrization of the air affects both human health and their physical and mental activity. The results of this analysis are presented here. It is also shown that these results can be useful for residents of some other countries.","PeriodicalId":69096,"journal":{"name":"人体生理学杂志(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42201577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Several Theoretical and Applied Problems of Human Extreme Physiology: Mathematical Modeling","authors":"Grygoryan R.D.","doi":"10.30564/jhp.v3i2.4175","DOIUrl":"https://doi.org/10.30564/jhp.v3i2.4175","url":null,"abstract":"Human cardiovascular system (CVS) and hemodynamics are critically sensitive to essential alterations of mechanical inertial forces in directions of head-legs (+Gz) or legs-head (-Gz). Typically, such alterations appear during pilotage maneuvers of modern high maneuverable airspace vehicles (HMAV).The vulnerability of pilots or passengers of HMAV to these altering forces depends on their three main characteristics: amplitude, dynamics, and duration. Special protections, proposed to minimize this vulnerability, should be improved in parallel with the increasing of these hazardous characteristics of HMAVs. Empiric testing of novel protection methods and tools is both expensive and hazardous. Therefore computer simulations are encouraged. Autonomic software (AS) for simulating and theoretical investigating of the main dynamic responses of human CVS to altering Gz is developed. AS is based on a system of quantitative mathematical models (QMM) consisting of about 1300 differential and algebraic equations. QMM describes the dynamics of both CVS (the cardiac pump function, baroreceptor control of parameters of cardiovascular net presented by means of lumped parameter vascular compartments) and non-biological variables (inertial forces, and used protections). The main function of AS is to provide physiologist-researcher by visualizations of calculated additional data concerning characteristics of both external and internal environments under high sustained accelerations and short-time microgravity. Additionally, AS can be useful as an educational tool able to show both researchers and young pilots the main hemodynamic effects caused by accelerations and acute weightlessness with and without use of different protection tools and technics. In this case, AS does help users to optimize training process aimed to ensure optimal-like human tolerance to the altered physical environment. Main physiological events appearing under different scenarios of accelerations and microgravity have been tested.","PeriodicalId":69096,"journal":{"name":"人体生理学杂志(英文)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43935576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanomedicine for SARS-CoV-2: Therapeutic and Prophylactic Approach in Immunocompromised Individuals","authors":"Basma H. Marghani","doi":"10.30564/jhp.v3i2.3437","DOIUrl":"https://doi.org/10.30564/jhp.v3i2.3437","url":null,"abstract":"SARS-CoV-2 is a novel coronavirus that first appeared in Wuhan, China in December 2019 and then spread all over the world, causing a global respiratory epidemic COVID-19 illness. Certain health conditions can increase your exposure to COVID-19, such as chronic obstructive lung disease, high blood pressure, cardiovascular disease, and diabetes. The immune system of the host is severely compromised in the event of a respiratory viral infection. Immunocompromised patients have a more difficult time avoiding respiratory viral infections, making them more vulnerable to COVID-19 pneumonia and increasing the death rate to 19%. The ability of SARS-CoV-2 to damage the host cell by modifying its own DNA or RNA and proliferating inside the host cell, with antiviral treatments and prophylactic vaccinations being tested. In recent years, numerous innovative technologies have been examined to diagnose, prevent and treat viral infections. Nano technology opens the way to distinguish the living cell mechanisms and develop new technologies that make it possible to diagnose and cure various viral infections in the early stage. The therapeutic and preventative approaches of nanomedicine are essential factors for curing SARS-CoV-2. The delivery of antiviral drugs based on nanocarrier, changes in pharmacokinetic/pharmacodynamic properties, leading in dose reduction, reductions in toxicity, increased bioavailability, and the prevention of the virus. The overall efficiency and safety of vaccinated adjuvant vaccine nanoparticles (VANs) helps enhance the immune response of older, immunocompromised persons with the greatest death rate of SARS-CoV-2. The review focuses on recent advancements in nanomedicine treatments and prevention strategies for SARS-CoV-2.","PeriodicalId":69096,"journal":{"name":"人体生理学杂志(英文)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47129186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Irisin/FNDC5: A Novel Player in Musculoskeletal Health","authors":"","doi":"10.31829/2691-5391/jhp2020-3(1)-107","DOIUrl":"https://doi.org/10.31829/2691-5391/jhp2020-3(1)-107","url":null,"abstract":"Osteoporosis is a major health problem that affects mainly aging and postmenopausal\u0000women and is characterized by low bone mass and structural deterioration of bone tissue, leading to bone fragility. Emerging shreds of evidence suggested that physical exercise has a beneficial effect on bone loss/osteoporosis. Irisin is a novel hormone-like myokine that was reported in 2012 and proposed to be produced in abundance by skeletal muscle as well as bone tissue in response to exercise. The studies have provided shreds of evidence that irisin can promote osteoblast differentiation, mineralization and increases bone mass and mechanical strength, and geometry in mice. We also review the autocrine effects of irisin in skeletal muscle, in which it upregulates expression of several pro-myogenic and exercise response genes in\u0000skeletal muscle including the expression of its precursor (FNDC5). In this review, we emphasize the structure and function of irisin and its functional role in skeletal homeostasis as well as skeletal muscle mass and regeneration. Further, the review narrates the future efficacy of irisin restoring the bone and reversing muscle wasting and could be developed as an irisin-based therapy for physically weaken and osteoporosis patients.","PeriodicalId":69096,"journal":{"name":"人体生理学杂志(英文)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46928533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From Cardiopulmonary Resuscitation, Cardiopulmonary Exercise Test and Cardiopulmonary Coupling to NewTheory of Holistic Integrative Physiology and Medicine","authors":"","doi":"10.31829/2691-5391/jhp2020-3(1)-106","DOIUrl":"https://doi.org/10.31829/2691-5391/jhp2020-3(1)-106","url":null,"abstract":"The Holistic Integrative Physiology and Medicine (HIPM), which was firstly purposed by Xing-Guo Sun since 2011 at APS conference, is a brand-new concept of physiology and medicine for human being. It originated from the philosophy of traditional Chinese and Western medicine and culture. It steps upon the coupling ideas of systems, such as cardiopulmonary resuscitation (CPR) by Yuan-Chang Wang and Kouwenhoven, cardiopulmonary exercise testing (CPET) by Karlman Wasserman and cardiopulmonary coupling (CPC) and integrated physiology. HIPM’s concept is always combining not only “Holistic” but “Integrative” (rather than integrated), not only time but space, not only normal (i.e. physiology) but abnormal (i.e. pathophysiology and medicine) for human physiology and medicine: only one inseparable set in whole contenting the all functional systems and their control and regulation in human being are internally integrative altogether, rather than the integrated one-by-one system of two or more systems as integrative physiology in systemic physiology. HIPM approaches the mechanism of neurohumoral control and regulation with the integration of all systems in the human body. We described the rough constructural frame of HIPM theory and clearly explained many unique questions in physiological and medical and pathophysiological mechanism of patients with chronic diseases (CDs). With HIPM, we can widely apply the methods of CPET, CPC and continuous functional monitoring for accurate diagnosis and differential diagnosis, evaluation, training, treatment, rehabilitation, prognosis and prevention in clinical medicine. We also can accurately and quantitatively manage CDs and do initial successful practice of integration of optimized traditional therapy, rehabilitation, health care and management, eating, drinking, exercise, sleep and lifestyle modification in China. The implementation and popularization of HIPM has the excellent opportunity and prospect. HIPM is the future of human physiology and medicine.","PeriodicalId":69096,"journal":{"name":"人体生理学杂志(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42176383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Effect of Kapalbhati Yoga on Cardiac Autonomic Control Using Heart Rate Variability Analysis in Healthy Male Individuals","authors":"Rajeev Gupta","doi":"10.30564/JHP.V2I1.1755","DOIUrl":"https://doi.org/10.30564/JHP.V2I1.1755","url":null,"abstract":"Kapalbhati is well known for improving cardiovascular health. But there are some reports of heart attacks while practising kapalbhati. We hypothesize that ill-effect of kapalbhati could be because of autonomic dysfunction to heart. In the present study, we aim to understand the acute effect of kapalbhati yoga on heart rate dynamics using heart rate variability (HRV) analysis. Resting heart rate (HR) varies widely in different individuals and during various physiological stresses, particularly, exercise it can go up to three-fold. These changes in heart rate are known as heart rate variability (HRV). Variability in heart rate reflects the control of autonomic system on the heart and which can be determined during brief periods of electrocardiographic (ECG) monitoring. HRV measures the effect of any physical exercise on the heart rate using time- and frequency-domain methods. Frequency-domain method involves power spectral analyses of the beat-to-beat intervals (R-R intervals) variability data. When total power vs. frequency, fast fourier transform analysis of R-R intervals data is done, it shows three well-defined peaks/rhythms in every individual, which contain different physiological information. Thus, the total spectral power of R-R intervals data can be divided into three components or bands viz., the very low frequency (VLF) band, the low-frequency (LF) band and the high frequency (HF) band. VLF represent very long time-period physiological phenomenon like thermoregulation, circadian rhythms etc. and thus are not seen in short-term recordings like in this work. LF band power represents long period physiological rhythms in the frequency range of 0.05- 0.15 Hz and LF band power increases as a consequence of sympathetic activation. HF band represent physiological rhythms in the frequency range of 0.15-0.5 Hz and they are synchronous with the respiration rate, and arise due to the intrathoracic pressure changes and mechanical vibrations caused by the breathing activity. In this work, twenty healthy male volunteers were trained in kapalbhati yoga and their ECG waveforms (2 min.) were obtained while doing kapalbhati (breathing at 1 Hz frequency for 2 min.) and were compared with the baseline (just 2 min. before the start) and post-kapalbhati (immediately 2 min. after completing the practice) HRV data. Our results showed a significant decrease in the time-domain measures i.e., NN50, pNN50 and the mean heart rate interval during-kapalbhati when compared statistically to the respective before practice or “pre”-kapalbhati (p < 0.05, student’s paired t-test) values. Frequency-domain indices showed that during-kapalbhati there is a significant increase (~48%) in the LF band power which suggests sympathetic activation and a significant increase (~88%) in the low frequency to the high frequency power ratio (LF/HF ratio) which indicates sympathetic system predominance. A significant decrease (~63%) in the HF component was also noted during-kapalbhati as com","PeriodicalId":69096,"journal":{"name":"人体生理学杂志(英文)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43979998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Regulatory B Cell in Active Systemic Lupus Erythematosus Patients: A Systemic Review and Meta-analysis","authors":"Xiao-Huan Chen, Lei Liu, L. Liao, Yahui Wang, Jiachen Shi, Hanyou Mo","doi":"10.30564/JHP.V2I1.1594","DOIUrl":"https://doi.org/10.30564/JHP.V2I1.1594","url":null,"abstract":"Background: The study of regulatory B cells (Bregs) in systemic lupus erythematosus (SLE) has been in full swing in recent years, but the number and function of Bregs in SLE patients have also present quite contradictory results. Therefore, we conducted a meta-analysis to verify the changes in Bregs in active SLE. Methods: We identified studies reporting the proportions of Bregs in SLE patients by searching Pubmed, Embase, Web of Science, Cochrane and CNKI. Due to the degree of heterogeneity is very high, we used a random effects model to assess the mean differences in percentages of Bregs between active SLE and controls. Then, sensitivity analysis and subgroup analysis were performed to verify potential sources of heterogeneity. Results: Seven eligible articles involving 301 active SLE patients and 218 controls were included in the meta-analysis. The pooled percentages of Bregs were found no significant difference between active SLE patients and healthy controls [0.259, (−1.150, 1.668), p = 0.719], with great heterogeneity ( I2 = 97.5%) . The result of sensitivity analysis showed that exclusion of any single study or single article did not materially resolve the heterogeneity, but after excluding the article conducted by Cai X and his colleagues, the percentages of Bregs were significantly higher in active SLE than those in controls [1.394, (0.114,2.675), p = 0.033]. The results of subgroup analysis revealed that when the disease activity was judged by SLEDAI score ≥ 5, the percentages of Bregs were significantly lower in the SLE groups than in the control groups[-1.99,(-3.241,-0.739), p = 0.002], but when the threshold of SLEDAI score ≥ 6 chosen for active SLE, the percentages of Bregs were significantly increased in the SLE groups[2.546,(1.333,3.759), p < 0.001]. Meanwhile, other subgroup analysis based on the different phenotypes of Bregs, diagnostic criteria, enrolled research countries, treatment status, and organ involvement did not differ in proportion of Bregs between SLE patients and controls. Conclusions: The study implies that Bregs may play a role in the pathogenesis of active SLE, and the thresholds of SLEDAI score to distinguish between active and inactive SLE patients are important factors affecting the percentages of Bregs.","PeriodicalId":69096,"journal":{"name":"人体生理学杂志(英文)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44212603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Use of Electromagnetic Forces of the Earth in Manual and Physiotherapy","authors":"Yuri Pmvovarenko","doi":"10.30564/JHP.V2I1.1608","DOIUrl":"https://doi.org/10.30564/JHP.V2I1.1608","url":null,"abstract":"Physiotherapists usually ignore the electric polarization of human bodies that occurs under the influence of the electromagnetic forces of the Earth. This is irrational, since the positive or negative electrification of human tissues has the opposite effect on both their properties and functional activity. How physiotherapists must take into account the polarizing effect of the electromagnetic forces of the Earth when analysing the functional states of the tissues of the human body is shown here. It also shows how these electromagnetic forces can be used by manual and physiotherapists.","PeriodicalId":69096,"journal":{"name":"人体生理学杂志(英文)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45982881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in Microvascular Reactivity and Systemic Vascular Resistance in Patients With Psoriasis","authors":"","doi":"10.31829/2691-5391/jhp2020-3(1)-105","DOIUrl":"https://doi.org/10.31829/2691-5391/jhp2020-3(1)-105","url":null,"abstract":"The aim: of this pilot study was to explore local blood flow in psoriatic plaques and normal skin before and after provocations known to alter cutaneous vascular resistance in order to test whether the increased flow was caused by a failure of normal vascular control processes in plaque skin and what association it has with cardiovascular parameters. Material and methods: 11 patients who had a diagnosis of psoriasis vulgaris were enrolled in the study. Cutaneous blood flow was recorded over plaque and clinically normal skin. 10 healthy sex and age matched subjects were selected as controls. Blood flow in psoriatic and normal skin was measured by a single- channel Laser Doppler blood flowmeter (Blood Flow meter, AD Instruments Ltd., Oxford, UK). Post-occlusive reactive hyperaemia was assessed on the plaque and non-plaque site. Cardiovascular parameters: heart rate, systolic and diastolic pressure, cardiac output, and vascular resistance were continuously monitored by a Finapres (FINAPRES Medical Systems, The Netherlands). Results: In patients, basal-LD flow was significantly higher in psoriatic skin compared to nonpsoriatic skin and significantly higher than in the controls. However, the post-occlusive hyperaemia test did not reveal significant differences between the patients and control subjects. Systemic vascular resistance was significantly lower in patients with psoriasis compared to healthy individuals. Conclusions: The results suggest that reduced microvascular resistance is associated with a significant increase in blood flow of psoriatic plaques and with lower systemic vascular resistance.","PeriodicalId":69096,"journal":{"name":"人体生理学杂志(英文)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46942325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}