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Acta leprologica最新文献

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[Nature and sensitivity of bacteria superinfecting plantar ulcers caused by leprosy at the Marchoux Institute, Bamako, Mali]. [马里巴马科Marchoux研究所麻风病引起的足底溃疡细菌的性质和敏感性]。
Acta leprologica Pub Date : 1999-01-01
A Tiendrebeogo, I Coulibaly, A M Sarr, S O Sow
{"title":"[Nature and sensitivity of bacteria superinfecting plantar ulcers caused by leprosy at the Marchoux Institute, Bamako, Mali].","authors":"A Tiendrebeogo,&nbsp;I Coulibaly,&nbsp;A M Sarr,&nbsp;S O Sow","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>To determine potential usefulness of antimicrobial agents and to guide their prescription in the treatment of leprosy plantar ulcers, we conducted an in vitro study about germs' nature and sensitivity to antibiotics. We took samples of plantar ulcers secretion from 107 patients at Marchoux Institute. 92.5% of those ulcers were infected. These samples revealed 145 strains of micro-organisms among those, Staphylococcus aureus (70 strains) and genus Pseudomonas (41 strains) were the most frequent. These bacteria were resistant to several antibiotics currently used at Marchoux Institute (tetracycline, penicillin, cotrimoxazol and erythromicin). Antibiotics, efficient at 80% on tested strains, were expensive for patients. They cannot be recommended for the treatment of local infections. These results outline that the main treatment in plantar ulcers is based upon antiseptic solutions and keeping feet at rest. Antibiotherapy in case of extension of local infection would be based on the results of a previous study of sensitivity.</p>","PeriodicalId":6905,"journal":{"name":"Acta leprologica","volume":"11 4","pages":"153-9"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21822013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Epidemiologic study of Hansen's disease in France at the dawn of the year 2000]. [2000年初法国汉森病的流行病学研究]。
Acta leprologica Pub Date : 1999-01-01
B Flageul
{"title":"[Epidemiologic study of Hansen's disease in France at the dawn of the year 2000].","authors":"B Flageul","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":6905,"journal":{"name":"Acta leprologica","volume":"11 4","pages":"129-30"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21821349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[How does one treat the osteitis and osteoarthritis of the extremities in older leprosy patients using granulated table sugar?]. [如何用砂糖治疗老年麻风病患者的四肢骨炎和骨关节炎?]
Acta leprologica Pub Date : 1999-01-01
M Y Grauwin, J L Cartel, J P Lepers
{"title":"[How does one treat the osteitis and osteoarthritis of the extremities in older leprosy patients using granulated table sugar?].","authors":"M Y Grauwin,&nbsp;J L Cartel,&nbsp;J P Lepers","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A common problem of osteitis and septic arthritis is the recurrent bone infection after surgical debridement, a problem frequently encountered in patients with sequela leprosy. In these cases the authors propose the use of an ancient method of post surgical wound care based on the treatment with ordinary granulated sugar. The hyperosmolar climate created this way in the wounds inhibits the bacterial growth, enhances bacterial death and therefore permits the growth of granulation tissue in order to recover the debrided nude bones. At ILAD (Leprosy Institute of Dakar), 36 osteitis and septic arthritis were treated and healed during the last 2 years from March 1995 to March 1997 using this technic. All the wounds healed in the mean-time of 44 days. Only two of them needed a second debridement and healed afterwards. Up to now the method using ordinary sugar was applied in the treatment of infected wounds, eschars and postsurgical infections. Our experience shows that it also can be indicated to treat bone infections. This method is easy to apply also under often difficult field conditions and is very cheap.</p>","PeriodicalId":6905,"journal":{"name":"Acta leprologica","volume":"11 4","pages":"147-52"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21822012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Hansen's disease and its control]. [汉森氏病及其控制]。
Acta leprologica Pub Date : 1999-01-01
{"title":"[Hansen's disease and its control].","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":6905,"journal":{"name":"Acta leprologica","volume":"11 2","pages":"59-67"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40039135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Histology and immuno-histology of lesions clinically suspicious of leprosy. 临床怀疑为麻风病变的组织学和免疫组织学。
Acta leprologica Pub Date : 1999-01-01
M Natrajan, K Katoch, V M Katoch
{"title":"Histology and immuno-histology of lesions clinically suspicious of leprosy.","authors":"M Natrajan,&nbsp;K Katoch,&nbsp;V M Katoch","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Forty-six patients presenting with lesions clinically suspicious of leprosy were selected among patients attending the outpatient department (OPD) of our Institute. The lesions were biopsied deeply for histological analysis. The cases chosen commonly belonged to the 20-35 years age group, were predominantly males, with rare cases of leprosy within the family (2/46, 4.35%). The clinical presentation in most of the cases was that of a solitary lesion, (44/46, 95.65%) located in one of the extremities (40/46, 86.95%). A positive Mitsuda reaction could be elicited in 40% of the cases. Routine histopathologic analysis using defined criteriae, has established the diagnosis of leprosy in 16/46 (34.78%) cases with positivity for acid-fast bacilli in 4 cases. The remaining cases (25/46, 54.35%) exhibited a non-specific histopathology with a perivascular/periadnexal mononuclear cell infiltrate, few (5/46, 10.86%) exhibited minimal or no histopathological features. The sections with nonspecific or minimal pathology when immunostained for the presence of mycobacterial antigen exhibited positivity in 11/30 (36.6%) cases. Presuming the features observed to be consequent to the presence of antigens nearby, the diagnosis of leprosy was significantly enhanced compared to the diagnosis achieved with routine histopathology alone.</p>","PeriodicalId":6905,"journal":{"name":"Acta leprologica","volume":"11 3","pages":"93-8"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21406608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Let us profit from the lessons" of the 15th International Leprosy Congress]. [让我们从第十五届国际麻风病大会的经验教训中获益]。
Acta leprologica Pub Date : 1999-01-01
M F Lechat
{"title":"[Let us profit from the lessons\" of the 15th International Leprosy Congress].","authors":"M F Lechat","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":6905,"journal":{"name":"Acta leprologica","volume":"11 2","pages":"35-8"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40039129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Hansen's disease in the territorial collective of Mayotte (Indian Ocean); retrospective study from 1990-1998]. [马约特岛(印度洋)集体领土的汉森病;1990-1998年的回顾性研究]。
Acta leprologica Pub Date : 1999-01-01
G Y De Carsalade, A Achirafi, B Flageul
{"title":"[Hansen's disease in the territorial collective of Mayotte (Indian Ocean); retrospective study from 1990-1998].","authors":"G Y De Carsalade,&nbsp;A Achirafi,&nbsp;B Flageul","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Mayotte French island of the Comoro Islands in the Indian Ocean, is located in a leprosy endemic area including the other islands of the archipelago and Madagascar island. As the last Hansen's disease epidemiological study in the island have been reported in 1982, we achieved a new valuation by a retrospective study on the 1990-1998 period. Our investigation showed that the disease was still endemic with a prevalence of 32/100,000 population in 1998 and an high annual new case detection rate (14 to 31/100,000 population). The profile of the newly detected cases was the same that reported at the world level (prédominance of males, less than 45-years old adults and paucibacillary forms) with two exceptions: the high percentage of children below 15 years of age (28.2%) and of family cases (25.3%). Moreover, 12.6% of the new cases exhibited disabilities grade 2 at the time of the diagnosis. These features emphasize the need for an enhanced leprosy control in this island which has a well-developed medical assistance.</p>","PeriodicalId":6905,"journal":{"name":"Acta leprologica","volume":"11 4","pages":"133-7"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21822010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Detection of viable organisms in leprosy patients treated with multidrug therapy. 多药治疗麻风病患者活菌检测。
Acta leprologica Pub Date : 1999-01-01
U D Gupta, K Katoch, H B Singh, M Natrajan, V D Sharma, V M Katoch
{"title":"Detection of viable organisms in leprosy patients treated with multidrug therapy.","authors":"U D Gupta,&nbsp;K Katoch,&nbsp;H B Singh,&nbsp;M Natrajan,&nbsp;V D Sharma,&nbsp;V M Katoch","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Cutaneous biopsies were collected from multibacillary leprosy patients who attended the out-patient department of Jalma Institute for treatment at different time intervals, i.e. 6 months, 12 months, 18 months, 24 months, 30 months, 36 months and 42 months after starting multidrug therapy (MDT) when they were still skin smear positive. Biopsies were processed for inoculation into mouse foot pad (MFP) and estimation of bacillary ATP levels by bioluminescent assay (ATP assay) by earlier established procedures. Viable bacilli were detectable after 1 year (25% cases by MFP and 31% cases by ATP assay), 2 years (8% cases by MFP and 12% cases by ATP assay) and 3 years (4% cases by both MFP and ATP assays). Overall, the percentage of the persisters was 10% by MFP and 13% by ATP assay. It would be important to carry out surveillance studies in larger number of BL/LL cases to know the trends and also the resultant relapses.</p>","PeriodicalId":6905,"journal":{"name":"Acta leprologica","volume":"11 3","pages":"89-92"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21406607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Social aspects and rehabilitation]. [社会方面和康复]。
Acta leprologica Pub Date : 1999-01-01
{"title":"[Social aspects and rehabilitation].","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":6905,"journal":{"name":"Acta leprologica","volume":"11 2","pages":"69-78"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40039136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Bibliography]. [参考文献]。
Acta leprologica Pub Date : 1999-01-01
{"title":"[Bibliography].","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":6905,"journal":{"name":"Acta leprologica","volume":"11 4","pages":"185-202"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21873440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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