世界胃肠病理生理学杂志(电子版)(英文版)最新文献

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Eosinophilic esophagitis: From pathophysiology to treatment. 嗜酸性粒细胞食管炎:从病理生理到治疗。

世界胃肠病理生理学杂志(电子版)(英文版) Pub Date : 2015-11-15 DOI: 10.4291/wjgp.v6.i4.150

A. D'alessandro, D. Esposito, M. Pesce, R. Cuomo, G. D. De Palma, G. Sarnelli

{"title":"Eosinophilic esophagitis: From pathophysiology to treatment.","authors":"A. D'alessandro, D. Esposito, M. Pesce, R. Cuomo, G. D. De Palma, G. Sarnelli","doi":"10.4291/wjgp.v6.i4.150","DOIUrl":"https://doi.org/10.4291/wjgp.v6.i4.150","url":null,"abstract":"Eosinophilic esophagitis (EoE) is a chronic immune disease, characterized by a dense eosinophilic infiltrate in the esophagus, leading to bolus impaction and reflux-like symptoms. Traditionally considered a pediatric disease, the number of adult patients with EoE is continuously increasing, with a relatively higher incidence in western countries. Dysphagia and food impaction represent the main symptoms complained by patients, but gastroesophageal reflux-like symptoms may also be present. Esophageal biopsies are mandatory for the diagnosis of EoE, though clinical manifestations and proton pump inhibitors responsiveness must be taken into consideration. The higher prevalence of EoE in patients suffering from atopic diseases suggests a common background with allergy, however both the etiology and pathophysiology are not completely understood. Elimination diets are considered the first-line therapy in children, but this approach appears less effective in adults patients, who often require steroids; despite medical treatments, EoE is complicated in some cases by esophageal stricture and stenosis, that require additional endoscopic treatments. This review summarizes the evidence on EoE pathophysiology and illustrates the safety and efficacy of the most recent medical and endoscopic treatments.","PeriodicalId":68755,"journal":{"name":"世界胃肠病理生理学杂志(电子版)(英文版)","volume":"6 4 1","pages":"150-8"},"PeriodicalIF":0.0,"publicationDate":"2015-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71059120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 38

Psychosocial impact of irritable bowel syndrome: A brief review. 肠易激综合征的社会心理影响:简要回顾。

世界胃肠病理生理学杂志(电子版)(英文版) Pub Date : 2015-11-15 DOI: 10.4291/wjgp.v6.i4.120

S. Ballou, Alyse Bedell, L. Keefer

引用次数: 28

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