中华内科杂志最新文献

{"title":"[Technical standards for performing radiofrequency catheter ablation for atrial fibrillation: a series of consortium standards].","authors":"","doi":"10.3760/cma.j.cn112138-20240907-00559","DOIUrl":"https://doi.org/10.3760/cma.j.cn112138-20240907-00559","url":null,"abstract":"<p><p>Atrial fibrillation (AF) has emerged as a major global cardiovascular disease in the 21st century. In China, there are greater than 12 million patients with AF, and its incidence continues to rise. AF affects patients' quality of life and significantly increases the risks of mortality, stroke, heart failure, cognitive impairment, and dementia. In recent years, multiple clinical guidelines have expanded the indications for catheter ablation and raised its level of recommendation. Concurrently, there has been a rapid and sustained increase in the number of AF ablation procedures performed across China. Among these, radiofrequency catheter ablation remains the most used method. Consequently, the Chinese Heart Rhythm Society of the Chinese Society of Biomedical Engineering, in collaboration with 40 arrhythmia centers and 60 leading clinical experts specializing in AF catheter ablation, developed a comprehensive set of standards. These standards were developed based on extensive clinical experience accumulated in recent years and the latest national and international AF guidelines and consensus documents. They address five critical domains: periprocedural management, intra-atrial septal puncture, anatomical reconstruction and electroanatomic mapping, ablation, and complication identification and management. By providing a structured framework, these standards aim to guide AF catheter ablation practice, thereby enhancing procedural safety and efficacy.</p>","PeriodicalId":68309,"journal":{"name":"中华内科杂志","volume":"64 1","pages":"23-35"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142959667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The diagnosis and treatment of chimeric antigen receptor T-cell associated hemophagocytic lymphohistiocytosis].","authors":"J L Hu, C C Feng, L B He, Y N Wang","doi":"10.3760/cma.j.cn112138-20240506-00284","DOIUrl":"https://doi.org/10.3760/cma.j.cn112138-20240506-00284","url":null,"abstract":"","PeriodicalId":68309,"journal":{"name":"中华内科杂志","volume":"64 1","pages":"77-82"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142959669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The impact of frailty on the prognosis of chronic heart failure patients treated with cardiac resynchronization therapy defibrillator implantation].","authors":"L Gao, H S Lyu, B P Tang, X H Zhou, X C Cheng, Y Q Shi, Y D Li, J H Zhang, Q Xing, Tuerhong Zukela, Y M Lu","doi":"10.3760/cma.j.cn112138-20240827-00537","DOIUrl":"https://doi.org/10.3760/cma.j.cn112138-20240827-00537","url":null,"abstract":"<p><p><b>Objective:</b> The aim of this study was to assess the frailty status of patients with heart failure undergoing CRT-D and then explore the predictive value of frailty for all-cause mortality and heart failure-related readmissions in these patients. <b>Methods:</b> We retrospectively included 374 patients with chronic heart failure who underwent CRT-D treatment at the First Affiliated Hospital of Xinjiang Medical University between June 2020 and June 2024. Based on the Tilburg Debilitation Assessment Scale, 175 patients (46.8%) were classified as frail while 199 (53.2%) were classified as non-frail. The baseline data between the two groups was compared using Cox regression analysis and Kaplan-Meier curves were used for survival analysis. <i>P</i>-values of <0.05 indicated statistically significant differences. <b>Results:</b> A total of 374 patients aged 25-93 (68±11) years were enrolled in this study, 101 (27.0%) of which were female. Among these, 175 (46.8%) were categorized as frail, and 199 (53.2%) were classified as non-frail. Over a median follow-up time of 23 (5, 45) months, 35 (9.4%) patients experienced all-cause mortality, with 30 (17.1%) deaths occurring in the frail group and 5 (2.5%) in the non-frail group; meanwhile, readmission events due to heart failure occurred in a total of 174 (46.5%) patients, including 122 (70.1%) in the frail group, and 52 (29.9%) in the non-frail group. Cox analysis showed that frailty was a significant determinant of all-cause mortality (<i>HR</i>=21.25, 95%<i>CI</i> 3.99-113.30, <i>P</i><0.001) and readmission among heart failure patients receiving CRT-D (<i>HR</i>=2.52, 95%<i>CI</i> 1.73-3.68, <i>P</i><0.001). Log-rank tests showed that the survival rate of patients in the frail group was significantly lower than that of patients in the non-frail group (<i>HR</i>=7.22, 95%<i>CI</i> 2.80-18.60, <i>P</i><0.001) and the risk of readmission events due to heart failure was significantly higher among patients in the frail group than among those in the non-frail group (<i>HR</i>=2.75, 95%<i>CI</i> 1.98-3.81, <i>P</i><0.001). <b>Conclusions:</b> Frailty is an independent predictor of postoperative all-cause mortality and the occurrence of heart failure-related readmissions in patients with heart failure treated receiving CRT-D.</p>","PeriodicalId":68309,"journal":{"name":"中华内科杂志","volume":"64 1","pages":"45-51"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142959671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Interpretation of the transparent reporting of a multivariable prediction model for individual prognosis or diagnosis based on regression or machine learning methods (TRIPOD+AI)].","authors":"M H Yan, Y Y Zhao, X Liu, W Li, Y Wang","doi":"10.3760/cma.j.cn112138-20240926-00609","DOIUrl":"https://doi.org/10.3760/cma.j.cn112138-20240926-00609","url":null,"abstract":"","PeriodicalId":68309,"journal":{"name":"中华内科杂志","volume":"64 1","pages":"4-10"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142959573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Exploring the association between mental stress, lymphocyte subset variations, and coronary lesion severity].","authors":"Y P Chi, L J Zhang, X R Huang, X R Shen, P J Rao, Y W Li, H Y Chen, M Y Liu","doi":"10.3760/cma.j.cn112138-20240718-00461","DOIUrl":"https://doi.org/10.3760/cma.j.cn112138-20240718-00461","url":null,"abstract":"<p><p><b>Objectives:</b> This study aimed to explore the association between perceived mental stress (MS), lymphocyte subset variations, and coronary lesion severity in patients with coronary artery disease (CAD). <b>Methods:</b> Patients with CAD were enrolled in this study from September 2023 to May 2024. Perceived Stress Scale-14 (PSS-14) was used to evaluate MS during the last 1 month. Lymphocyte subsets were analyzed, including the percentage and absolute counts of CD3⁺, CD3⁺CD4⁺, CD3⁺CD8⁺, CD3^-CD19⁺, CD3^-CD56⁺16⁺, and the Th/Ts ratio. Statistical analysis was conducted using SPSS 24.0. <b>Results:</b> This study recruited patients with 323 CAD, with an average age of 61 (56, 68) years, including 203 males and 120 females. According to the PSS-14, a score of 14-42 and 43-70 were categorized as normal and increased MS, respectively. Patients with CAD with increased MS had significantly higher Gensini scores than those with normal MS [37(19,64) vs. 28(12,50), <i>Z</i>=-2.19,<i>P</i>=0.029]. Male CAD patients with increased MS exhibited significantly higher Gensini scores [39(20, 58) vs. 26(12, 45), <i>Z</i>=-2.37, <i>P</i>=0.018], levels of CD3⁺CD8⁺%[28.3%(23.6%,36.6%) vs. 25.9%(21.0%,32.4%), <i>Z</i>=-2.05, <i>P</i>=0.041], and CD3⁺CD8⁺absolute value [485 (346, 675) vs. 396 (309, 510) cells/μl, <i>Z</i>=-2.55,<i>P</i>=0.011] than those with normal MS. In male patients with CAD, a positive correlation was observed between Gensini scores (correlation coefficient: 0.181, <i>P</i>=0.011), PSS-14 scores, and CD3⁺CD8⁺absolute value (correlation coefficient: 0.162,<i>P</i>=0.038). <b>Conclusion:</b> This study reveals a positive correlation between MS and coronary stenosis severity, with notable sex differences. In male patients with CAD, higher levels of MS are associated with more severe coronary stenosis. The potential underlying mechanism may involve the regulation of lymphocyte subsets<b>.</b></p>","PeriodicalId":68309,"journal":{"name":"中华内科杂志","volume":"64 1","pages":"36-44"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142959604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[IgAκ monoclonal immunoglobulin deposition disease: a case report].","authors":"S X Ai, Y B Wen, G Chen, Y Qin, K Zheng, X M Li","doi":"10.3760/cma.j.cn112138-20240708-00432","DOIUrl":"https://doi.org/10.3760/cma.j.cn112138-20240708-00432","url":null,"abstract":"","PeriodicalId":68309,"journal":{"name":"中华内科杂志","volume":"64 1","pages":"68-71"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142959608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Research progresses and hot topics of neurogenetic diseases in the past decade].","authors":"Z Y Wu","doi":"10.3760/cma.j.cn112138-20240603-00365","DOIUrl":"https://doi.org/10.3760/cma.j.cn112138-20240603-00365","url":null,"abstract":"","PeriodicalId":68309,"journal":{"name":"中华内科杂志","volume":"64 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142959578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Ovarian collision tumor with postmenopausal hyperandrogenism: a case report].","authors":"Z Xue, P Pang, Y Zhang, M H Zhang, Y Y Zhao, Y J Zhao, D Sun, L Y Song, Y Zhou, G Q Yang, Z H Lyu, J T Dou","doi":"10.3760/cma.j.cn112138-20240512-00298","DOIUrl":"10.3760/cma.j.cn112138-20240512-00298","url":null,"abstract":"","PeriodicalId":68309,"journal":{"name":"中华内科杂志","volume":"63 12","pages":"1252-1256"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142775075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Chinese expert consensus on the diagnosis and treatment of adult T-cell leukemia/lymphoma (2024)].","authors":"","doi":"10.3760/cma.j.cn112138-20240918-00586","DOIUrl":"10.3760/cma.j.cn112138-20240918-00586","url":null,"abstract":"<p><p>Adult T-cell leukemia/lymphoma (ATL), a rare and unique proliferative tumor of T lymphocytes, is associated with human T-cell leukemia virus type 1 (HTLV-1) infection. Due to its diverse clinical features, multidrug resistance of malignant cells, frequent opportunistic infection, and poor prognosis, ATL remains a clinical challenge. A unified understanding of ATL is currently lacking, and its diagnosis and treatment are not standardized in China due to the small number of cases. Therefore, to strengthen our understanding of ATL, hematology experts have formulated the \"Chinese expert consensus on the diagnosis and treatment of adult T-cell leukemia/lymphoma (2024)\" based on the latest research progress at home and abroad. This consensus proposes the latest diagnostic and subtype criteria for ATL in China. Furthermore, it briefly describes the infection situation of HTLV-1 in coastal areas of China, the epidemic trends in China, and the latest evidence and recommendations regarding the pathogenesis, clinical manifestations, and treatment strategies, with the aim to standardize the clinical diagnosis and treatment of ATL and ultimately improve the overall survival of patients with ATL.</p>","PeriodicalId":68309,"journal":{"name":"中华内科杂志","volume":"63 12","pages":"1196-1204"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142775051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Guidelines for the diagnosis and management of multiple myeloma in China (2024 revision)].","authors":"","doi":"10.3760/cma.j.cn112138-20240928-00616","DOIUrl":"https://doi.org/10.3760/cma.j.cn112138-20240928-00616","url":null,"abstract":"<p><p>Multiple myeloma (MM), an incurable clonal plasma cell dysplasia, is the second most common hematological malignancy in many countries, mainly developing in the elderly population. With the emergence of novel agents and laboratory methods, the diagnosis and treatment of MM have been significantly improved. In this version of the \"Guidelines for the diagnosis and management of multiple myeloma in China (2024 revision)\", several examination items have been updated in the diagnostic section; the definition of ultra high-risk MM has been proposed in the risk stratification section; for patients with equal or more than second-line relapse, chimeric antigen receptor T cell therapy and a bispecific T-cell engager have been added; and the treatment recommendations have been listed at different levels based on the best available evidence.</p>","PeriodicalId":68309,"journal":{"name":"中华内科杂志","volume":"63 12","pages":"1186-1195"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142775085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}