2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)最新文献_第4页

Polycrystalline Perovskite X-ray Detectors 多晶钙钛矿x射线探测器

2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Pub Date : 2020-10-31 DOI: 10.1109/NSS/MIC42677.2020.9508096

Logan J. Forth, H. Gibbard, Stephanie Biddlecombe, Isabel Braddock, C. Crean, J. C. Khong, Mingqing Wang, R. Speller, K. Choy, P. Sellin, R. Moss

{"title":"Polycrystalline Perovskite X-ray Detectors","authors":"Logan J. Forth, H. Gibbard, Stephanie Biddlecombe, Isabel Braddock, C. Crean, J. C. Khong, Mingqing Wang, R. Speller, K. Choy, P. Sellin, R. Moss","doi":"10.1109/NSS/MIC42677.2020.9508096","DOIUrl":"https://doi.org/10.1109/NSS/MIC42677.2020.9508096","url":null,"abstract":"Metal-halide perovskite materials have begun to attract much attention recently for their potential use in radiation detection applications. This interest is mainly due to their favourable semi-conductive properties, high electron density, ease of manufacture and relatively low cost compared to popular detector materials. In this paper we investigate inorganic caesium lead bromide (CsPbBr3). Polycrystalline powder samples were produced by solution growth and simple ‘sandwich’ devices were fabricated. The powder was manually ground and then pressed to form pellets of a few mm thickness. Gold planar electrodes were deposited on the top and bottom perovskite surfaces by evaporation and were connected to an external circuit. We have made comparative measurements of the photoluminescence (PL), dark current and temporal radiation response. The PL measurements showed stable emissions centred at 525 nm for CsPbBr3’ which is typical of these materials and within a useful range for this application. A CsPbBr3 device was exposed to X-rays and demonstrates a good increase in photocurrent over the dark current under both positive and negative bias with a sensitivity of 33.8 µCGy−1aircm−2and the temporal response was determined to be ~40 ms by measuring the photocurrent decay after X-ray illumination.","PeriodicalId":6760,"journal":{"name":"2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"30 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2020-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90482268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Laboratory Characterization of Innovative 3D Trench-design Silicon Pixel Sensors Using a Sub-Picosecond Precision Laser-Based Testing Equipment 使用亚皮秒精度激光测试设备的创新3D沟槽设计硅像素传感器的实验室表征

2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Pub Date : 2020-10-31 DOI: 10.1109/NSS/MIC42677.2020.9507747

M. Aresti, A. Cardini, A. Lai, A. Loi, G. Cossu, M. Garau, A. Lampis, G. Betta, G. Forcolin

{"title":"Laboratory Characterization of Innovative 3D Trench-design Silicon Pixel Sensors Using a Sub-Picosecond Precision Laser-Based Testing Equipment","authors":"M. Aresti, A. Cardini, A. Lai, A. Loi, G. Cossu, M. Garau, A. Lampis, G. Betta, G. Forcolin","doi":"10.1109/NSS/MIC42677.2020.9507747","DOIUrl":"https://doi.org/10.1109/NSS/MIC42677.2020.9507747","url":null,"abstract":"In the next generation of experiments at the future high luminosity particle colliders, the identification of the interaction and decay vertices will be an extremely difficult task because of the very large number of particles that will be produced at each bunch crossing. LHC experiments have shown that new vertex detectors with single-hit time resolutions of the order of 10 ps will allow to recover the current tracking and vertexing capabilities. The TimeSPOT project is developing 3D trench-based silicon pixel detectors with a time resolution below 30 ps. Initial beam test with a first sensors batch has showed that these detectors fulfill and even exceed these expectations. To carefully study their performances and optimize their design, it is important to precisely measure sensors time response over their active area. This paper summarize the preliminary measurements of this sensors developed within the TimeSPOT project performed in our laboratory, using a custom laser-based setup to deposit a known energy in specific regions of the pixel sensitive volume, allowing us to estimate the performances of these sensors under charge-particle illumination.","PeriodicalId":6760,"journal":{"name":"2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"80 2","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2020-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91422952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

An MLEM Reconstruction Method with Mixed Events Based on a Cascade Gamma Emission Imager System 基于级联伽马发射成像仪系统的混合事件MLEM重建方法

2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Pub Date : 2020-10-31 DOI: 10.1109/NSS/MIC42677.2020.9507850

Xiao Liu, Hui Liu, Li Cheng, Zheng Gu, R. Yao, Yaqiang Liu

{"title":"An MLEM Reconstruction Method with Mixed Events Based on a Cascade Gamma Emission Imager System","authors":"Xiao Liu, Hui Liu, Li Cheng, Zheng Gu, R. Yao, Yaqiang Liu","doi":"10.1109/NSS/MIC42677.2020.9507850","DOIUrl":"https://doi.org/10.1109/NSS/MIC42677.2020.9507850","url":null,"abstract":"Many medical radionuclides can emit cascade photons sequentially, yet commercial imaging equipment like PET or SPECT don't make use of this information. We have developed a cascade gamma emission imager system to detect the cascade photons in coincidence for those radionuclide imaging. In previous study, reasonable reconstruction images could be obtained using coincidence event based MLEM (CE-MLEM) but with a low signal-to-noise ratio (SNR), caused by the poor sensitivity of the coincidence event. In this work, we proposed an MLEM with mixed events (ME-MLEM) reconstruction method based on the coincidence events incorporated with the simultaneously detected single photons to improve the SNR while maintaining the spatial resolution. A myocardial phantom filled with 1 mCi 177Lu3+ solution was scanned for 1 hour on our prototype setup. 1.36xl04 coincidence events and 8.27×107 single photons were acquired under a 25.6 ns CTW and 10.8%/14.6% @ 208/113 KeV energy window. CE-MLEM, single photon based MLEM (SP-MLEM), and ME-MLEM with a 0.001 weighting factor between coincidence events and single photons were then used for the image reconstruction. The results showed the potential for ME-MLEM to improve the image SNR while keeping the same spatial resolution as CE-MLEM. Our results demonstrated that our system's image quality could be improved when combined coincidence events and single photons together.","PeriodicalId":6760,"journal":{"name":"2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"11 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2020-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79203501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stochastic Variance Reduction Optimisation Algorithms Applied to Iterative PET Reconstruction 随机方差缩减优化算法在PET迭代重建中的应用

2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Pub Date : 2020-10-31 DOI: 10.1109/NSS/MIC42677.2020.9508105

R. Twyman, S. Arridge, Bangti Jin, B. Hutton, L. Brusaferri, K. Thielemans

引用次数: 2

Arc-PET: Cost-Effective Whole-Body Scanner with High Sensitivity and High Spatial Resolution Arc-PET:具有高灵敏度和高空间分辨率的高性价比全身扫描仪

2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Pub Date : 2020-10-31 DOI: 10.1109/NSS/MIC42677.2020.9507815

Eric W. Petersen, Wei Zhao, A. Goldan

引用次数: 0

New results on high-resolution 3-D CZT drift strip detectors 高分辨率三维CZT漂移条带探测器的新结果

2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Pub Date : 2020-10-31 DOI: 10.1109/NSS/MIC42677.2020.9507987

L. Abbene, F. Principato, G. Gerardi, A. Buttacavoli, S. Altieri, C. Gong, N. Protti, M. Bettelli, N. S. Amadè, S. Zanettini, A. Zappettini, N. Auricchio, S. del Sordo, E. Caroli

{"title":"New results on high-resolution 3-D CZT drift strip detectors","authors":"L. Abbene, F. Principato, G. Gerardi, A. Buttacavoli, S. Altieri, C. Gong, N. Protti, M. Bettelli, N. S. Amadè, S. Zanettini, A. Zappettini, N. Auricchio, S. del Sordo, E. Caroli","doi":"10.1109/NSS/MIC42677.2020.9507987","DOIUrl":"https://doi.org/10.1109/NSS/MIC42677.2020.9507987","url":null,"abstract":"Intense research activities have been carry out in the development of room temperature gamma ray spectroscopic imagers, aiming to compete with the excellent energy resolution of high-purity germanium (HPGe) detectors (0.3 % FWHM at 662 keV) obtained after cryogenic cooling. Cadmium-zinc-telluride (CZT) detectors equipped with pixel, strip and virtual Frisch-grid electrode structures represented an appealing solution for room temperature measurements. In this work, we present the performance of new high-resolution CZT drift strip detectors (19.4 x 19.4 x 6 mm3), recently fabricated at IMEM-CNR of Parma (Italy) in collaboration with due2lab company (Reggio Emilia, Italy). The detectors, working in planar transverse field (PTF) irradiation geometry, are able to perform 3D positioning and energy measurement of X rays and gamma rays: 2D positioning through cross-strip electrode patterns on the cathode/anode electrodes and the third coordinate by exploiting the C/A ratio and/or the drift time. A 32-channel digital electronics was used to process and analyze the zoo of collected/induced charge pulses from the strips. Excellent room temperature energy resolution (0.9 % FWHM at 662 keV)characterizes the detectors, after the application of a new correction technique. These activities follow the goals of two Italian research projects (3DCaTM and 3CaTS projects funded by ASI and INFN, respectively) on the development of spectroscopic X-ray and gamma ray imagers (10 keV-1MeV) for medical and astrophysical applications.","PeriodicalId":6760,"journal":{"name":"2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"4 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2020-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88798189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

A 5-Axis Calibration Stage for Depth-of-Interaction-Correcting Scintillation Crystals 一种用于相互作用深度校正闪烁晶体的五轴校准平台

2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Pub Date : 2020-10-31 DOI: 10.1109/NSS/MIC42677.2020.9508049

Owen A. Anderson, L. Bläckberg, S. Sajedi, H. Sabet, L. Furenlid

引用次数: 1

Preliminary Optimized Design of a High-resolution PET Detector with a 0.5 mm Crystal Size 晶体尺寸为0.5 mm的高分辨率PET探测器的初步优化设计

2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Pub Date : 2020-10-31 DOI: 10.1109/NSS/MIC42677.2020.9507797

Xi Zhang, Baihezi Ye, S. Xie, Weijie Tao, Zhixiang Zhao, Qiu Huang, Jianfeng Xu, Q. Peng

引用次数: 0

Study of optical reflectors used in scintillation detectors that achieve 100 ps coincidence time resolution for TOF-PET 用于TOF-PET达到100ps符合时间分辨率的闪烁探测器的光学反射器的研究

2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Pub Date : 2020-10-31 DOI: 10.1109/NSS/MIC42677.2020.9507861

A. Gonzalez-Montoro, S. Pourashraf, M. S. Lee, J. Cates, Zhixiang Zhao, C. Levin

{"title":"Study of optical reflectors used in scintillation detectors that achieve 100 ps coincidence time resolution for TOF-PET","authors":"A. Gonzalez-Montoro, S. Pourashraf, M. S. Lee, J. Cates, Zhixiang Zhao, C. Levin","doi":"10.1109/NSS/MIC42677.2020.9507861","DOIUrl":"https://doi.org/10.1109/NSS/MIC42677.2020.9507861","url":null,"abstract":"Incorporating 511 keV photon time-of-flight (TOF) information in PET enables a significant boost in reconstructed image signal-to-noise ratio (SNR). This SNR boost depends on the 511 keV photon pair coincidence time resolution (CTR) of the PET system, which is determined by several factors including properties of the scintillation crystal and photodetector, crystal-to-sensor coupling configurations, and reflective materials. The goal of the present work is to achieve 100 picoseconds (ps) CTR for > 2-fold additional improvement in reconstructed image SNR compared to state-of-the-art PET systems that currently have 250–400 ps CTR. A critical parameter to optimize in achieving this goal is the optical reflector's influence on light collection and transit time to the photodetector. For the experimental set-up, we made use of PET detector elements based on both 3×3×10 and 3×3×20 mm3 LGSO crystals coupled to an array of SiPMs by using a novel “side-readout” configuration. We have tested the CTR performance by applying four different reflector materials to the crystal surfaces namely: Enhanced Specular Reflector (ESR), Teflon, BaSO4 paint and TiO2 paint. In addition, we have also evaluated the influence of the scintillation crystal length on the CTR performance by testing 3×3×10mm3 and 3×3×20mm3 LGSO crystals.","PeriodicalId":6760,"journal":{"name":"2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"10 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2020-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90729551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Developing Bayesian Networks based Prognostic Radiomics Model for Clear Cell Renal Cell Carcinoma Patients 基于贝叶斯网络的透明细胞肾细胞癌预后放射组学模型的建立

2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Pub Date : 2020-10-31 DOI: 10.1109/NSS/MIC42677.2020.9507825

M. Nazari, Isaac Shiri, H. Zaidi

{"title":"Developing Bayesian Networks based Prognostic Radiomics Model for Clear Cell Renal Cell Carcinoma Patients","authors":"M. Nazari, Isaac Shiri, H. Zaidi","doi":"10.1109/NSS/MIC42677.2020.9507825","DOIUrl":"https://doi.org/10.1109/NSS/MIC42677.2020.9507825","url":null,"abstract":"Clear cell renal cell carcinoma (ccRCC) is one of the most aggressive histologic subtype of RCC. In this study, we developed and evaluated a Bayesian network as a prognostic model using computed tomography (CT) radiomic features and clinical information to predict the risk of death within 5 years for ccRCC patients. Seventy patients who had abdominal CT scans with delayed post-contrast phase and outcome data were enrolled. 3D volumes of interest (VOIs) covering the whole tumor on CT images were manually delineated. Image preprocessing techniques including, wavelet, Laplacian of Gaussian, and resampling of the intensity values to 32, 64 and 128 bin levels were applied on all VOIs. Different radiomic features, including shape, first-order, and texture features were extracted from the VOIs. For features selection, we first used the z-score method to normalize all image features, then the relevant features were selected based on mutual information (MI) criteria. The patients were divided into a low- and high-risk group based on survival or death at 5 years after surgery, respectively. Bayesian networks were used as a classifier for risk stratification. The model was evaluated using the area under the curve (AUC), sensitivity, specificity, and accuracy by 1000 bootstra resampling. The Bayesian model with Laplacian of Gaussian (LOG) filter showed the best predictive performance in this cohort with an AUC, sensitivity, specificity, and accuracy of 0.94, 85 %, 94%, and 89%, respectively. The results of the current study indicated that prognostic models based on radiomic features are very promising tools for risk stratification for ccRCC patients.","PeriodicalId":6760,"journal":{"name":"2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)","volume":"7 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2020-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89901680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0