Journal of the Indian Institute of Science最新文献

{"title":"Guest Editorial: Multi-Fluid and Fluid–Structure Interactions in Biological Systems: Computational Methods and Applications","authors":"Atul Sharma, Ratnesh K. Shukla","doi":"10.1007/s41745-024-00433-9","DOIUrl":"10.1007/s41745-024-00433-9","url":null,"abstract":"","PeriodicalId":675,"journal":{"name":"Journal of the Indian Institute of Science","volume":"104 1","pages":"5 - 7"},"PeriodicalIF":2.3,"publicationDate":"2024-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145122180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Examining Bengaluru’s Potable Water Quality and the Usage and Consequences of Reverse Osmosis Technology in Treating the City’s Drinking Water","authors":"Sudhakar M. Rao,&nbsp;Nitish Venkateswarlu Mogili","doi":"10.1007/s41745-024-00435-7","DOIUrl":"10.1007/s41745-024-00435-7","url":null,"abstract":"<div><p>The presence of microbial and chemical impurities in surface and groundwater compels consumers to treat drinking water at the point of consumption. Chemically contaminated groundwater is usually purified by reverse osmosis (RO) technology. However, this technology wastes water as only a portion of raw water is treated and the remaining is discarded as RO reject with almost twice the salinity of the raw water. The study examines the potable water quality, the extent and consequences of usage of RO technology in the BBMP (Bruhat Bengaluru Mahanagara Palike) area of 575 km². Water quality maps indicated that the Cauvery river water is microbially contaminated during travel to the treatment plant. Comparatively, groundwater in some BBMP zones have TDS (total dissolved solids), F (fluoride) and Pb (lead) contamination, while all BBMP zones are contaminated by Fe (iron) and nitrate. Calculations projected that 49% of 29.1 lakh households consume 14.29 MLD (million liters per day) of RO water. Of the 49% households, 43% of households are treating the drinking water appropriately as they solely depend on groundwater. Six percent of households with Cauvery water supply are inappropriately using RO technology as they can consume UV treated Cauvery water. Usage of 14.29 MLD of RO water will generate 14.29–33.3 MLD of RO reject water with elevated salinity levels that eventually reach the inland water bodies. The consequences of elevated salinity levels from sewage discharge on a Bengaluru lake are illustrated.</p></div>","PeriodicalId":675,"journal":{"name":"Journal of the Indian Institute of Science","volume":"104 2","pages":"395 - 414"},"PeriodicalIF":1.8,"publicationDate":"2024-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141507090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editor's Desk","authors":"G. Ananthasuresh","doi":"10.1007/s41745-024-00434-8","DOIUrl":"10.1007/s41745-024-00434-8","url":null,"abstract":"","PeriodicalId":675,"journal":{"name":"Journal of the Indian Institute of Science","volume":"104 1","pages":"1 - 3"},"PeriodicalIF":2.3,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145121809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Review of CFD Based Simulations to Study the Hemodynamics of Cerebral Aneurysms","authors":"Eldhose Babu Maramkandam,&nbsp;Anjana Kannan,&nbsp;Chanikya Valeti,&nbsp;N. Manjunath,&nbsp;Nisanth Kumar Panneerselvam,&nbsp;Azhaganmaadevi K. Alagan,&nbsp;Pratik M. Panchal,&nbsp;Santhosh K. Kannath,&nbsp;H. R. Darshan,&nbsp;Ram Kishan Nekkanti,&nbsp;Bhushan Akade,&nbsp;George C. Vilanilam,&nbsp;Prakash Nair,&nbsp;Ganesh Divakar,&nbsp;Meraj Ahmed,&nbsp;B. J. Sudhir,&nbsp;B. S. V. Patnaik","doi":"10.1007/s41745-024-00431-x","DOIUrl":"10.1007/s41745-024-00431-x","url":null,"abstract":"<div><p>The human circulatory system facilitates supply of oxygen and nutrients to all the tissues in the body. This system consists of a net-work of closed-compliant tubes (the aorta, arteries, arterioles, capillaries, venules and veins, etc) of various sizes and lengths, start and terminate at the chambers of the heart. However, continuous flow of blood through these vessels is the genesis for the development of a number of circulation-related medical emergencies such as, myocardial infarction, stroke etc. Most problems in cerebral circulatory disorders are due to formation of constrictions, bulges, blockages or leakages. Correspondingly, the blood vessels are subjected to stenosis, aneurysms, stroke, brain hemorrhage etc. Computational Fluid Dynamics (CFD) engineers can employ mathematical models to analyze a number of <i>what-if</i> type scenarios of clinical interest, for patient-specific conditions. Present study covers cerebrovascular disorders such as Moyamoya Angiopathy (MMA), Arteriovenous malformations (AVM), Stroke, Stenosis and aneurysms in a broader sense, as the CFD tools are similar for all these flow problems. Literature is replete with modeling tools, methods for supporting clinical decisions prior to surgical/ endovascular intervention. Typically, CFD-based modeling starts with a radiological scan to identify the underlying disease-specific condition to segment the region of interest. Identified geometry is meshed and simulated with the aid of CFD-based solvers to develop hemodynamic parameters of clinical interest. Present study reviews the state-of-the-art regarding such tools and analyzes the modeling steps involved. This review is limited to the cerebrovascular disorders and the modelling of aneurysm rupture-risk prediction tools of importance to clinical decision making. In this review, a brief of CFD analysis of various clinical management options such as clipping, coiling, bypass etc are presented. Although most analysis is based on clinical parameters coupled with radiological features on a population cohort, CFD based tools are gradually gaining prominence. Development of reliable tools with and without fluid–structure interaction are central to providing confidence to the clinicians. Understanding blood flow and enabling necessary perfusion to various parts of the body is important to our healthy living and survival.</p></div>","PeriodicalId":675,"journal":{"name":"Journal of the Indian Institute of Science","volume":"104 1","pages":"77 - 110"},"PeriodicalIF":2.3,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141109481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: An Indian Tribute to William Morton Wheeler","authors":"Raghavendra Gadagkar","doi":"10.1007/s41745-024-00419-7","DOIUrl":"10.1007/s41745-024-00419-7","url":null,"abstract":"","PeriodicalId":675,"journal":{"name":"Journal of the Indian Institute of Science","volume":"105 :","pages":"401 - 401"},"PeriodicalIF":2.3,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140995228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Numerical Studies on Magnetic Driven Targeted Drug Delivery in Human Vasculature","authors":"Nikhil Kumar Tamboli,&nbsp;Janani Srree Murallidharan","doi":"10.1007/s41745-024-00428-6","DOIUrl":"10.1007/s41745-024-00428-6","url":null,"abstract":"<div><p>Magnetic driven targeted drug delivery (TDD) involves the manipulation of magnetic drug carriers, such as nano/micro particles or bubbles, within the body using external magnetic fields to precisely reach the intended target location. This method is utilized in treating severe illnesses like cancerous tumors and nervous disorders, offering higher efficacy with reduced drug dosages and side effects. While numerous studies have simulated magnetic driven TDD, comprehensive reviews remain scarce. This article presents an extensive review of computational/numerical work done on magnetic driven TDD utilizing both microbubbles and non-bubbles (nano/micro particles) within human vasculature and lung airways. The study aims to analyze the drug delivery problem from physical and numerical perspectives. Key highlights include artery wall models (rigid, flexible, or porous), models of force acting on particles, relevant governing equations, discussions on parameters of interest and their effects on drug delivery efficacy. Finally, the article briefly outlines common trends observed in magnetic driven TDD problems and their underlying physical principles.</p></div>","PeriodicalId":675,"journal":{"name":"Journal of the Indian Institute of Science","volume":"104 1","pages":"111 - 145"},"PeriodicalIF":2.3,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140882031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Decade of Volume-Of-Solid Immersed Boundary Solvers: Lessons Learnt and the Road Ahead","authors":"Mandeep Deka,&nbsp;Krishna Chandran,&nbsp;Ganesh Natarajan","doi":"10.1007/s41745-024-00429-5","DOIUrl":"10.1007/s41745-024-00429-5","url":null,"abstract":"<div><p>This review article traces the development of the Volume-Of-Solid immersed boundary method, referred to as VOS-IB, over the last decade. Starting from its simple beginnings inspired by the Volume-Of-Fluid method in multiphase flow, we discuss the evolution of this technique and its extensions for problems in Boussinesq and non-Boussinesq flows, conjugate heat transfer, multi-fluid flows, fluid–structure interactions, and turbulent flows. A critical assessment of the strengths and limitations of the VOS-IB technique is presented and possible directions for future research, both in terms of development of the method and its applications, are outlined.</p></div>","PeriodicalId":675,"journal":{"name":"Journal of the Indian Institute of Science","volume":"104 1","pages":"249 - 276"},"PeriodicalIF":2.3,"publicationDate":"2024-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140881713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Critical Review of Multiphase Modelling of Blood Flow in Human Cardiovascular System","authors":"Raghvendra Gupta,&nbsp;Amit Kumar,&nbsp;Mudrika Singhal","doi":"10.1007/s41745-024-00430-y","DOIUrl":"10.1007/s41745-024-00430-y","url":null,"abstract":"<div><p>In the human body, blood acts as a transporter of oxygen and other nutrients as well as carbon dioxide and other waste materials to and from all the organs. Therefore, continuous supply of blood to all the organs is critical for proper functioning of the human body. Blood is a complex fluid and has more than 40% flexible particles which include red blood cells, white blood cells, platelets and other proteins suspended in a water-like fluid, plasma. The dynamics of blood flow, known as haemodynamics, is critical in the development, diagnosis and treatment planning of vascular diseases and design and development of cardiovascular devices. Whilst the most advanced flow measurement techniques such as X-ray imaging, magnetic resonance imaging and ultrasound imaging are used in the diagnosis and treatment of vascular diseases, it is not possible to obtain the complete information of pressure and velocity field experimentally via in vivo methods. Therefore, in silico methods or computational modelling techniques are being increasingly employed not only to understand the haemodynamics but also for use in the clinical setting. Whilst blood is treated as a homogeneous, single-phase fluid in several studies, it is possible to capture several features of the flow of blood only by modelling it as a multiphase fluid. A number of approaches have been adopted to model multiphase flow of blood. A broad categorisation can be based on whether the cell boundary is captured explicitly, e.g. immersed boundary method, or the phases are treated as interpenetrating and two or more phases can exist simultaneously at a point, e.g. Euler–Euler method. In the literature, both the approaches have been adopted to model the flow of blood. Particle-based methods, such as smoothed particle hydrodynamics and dissipative particle dynamics have also been employed by researchers to study the complex interactions associated with the flow of blood. In this article, we discuss different multiphase modelling approaches and their application in the haemodynamics modelling.</p></div>","PeriodicalId":675,"journal":{"name":"Journal of the Indian Institute of Science","volume":"104 1","pages":"39 - 63"},"PeriodicalIF":2.3,"publicationDate":"2024-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140881716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fish-Inspired Oscillating and/or Undulating Hydrofoil in a Free Stream Flow: A Review on Thrust Generation Mechanisms","authors":"Sarvesh Shukla,&nbsp;Atul Sharma,&nbsp;Amit Agrawal,&nbsp;Rajneesh Bhardwaj","doi":"10.1007/s41745-024-00426-8","DOIUrl":"10.1007/s41745-024-00426-8","url":null,"abstract":"<div><p>A review of recent literature on thrust generation mechanisms by a hydrofoil, bioinspired from fish locomotion is presented. The present work considers fish-inspired periodic kinematics of three types: pitching, heaving, and undulations along with the combination of some of these motions. The pitching corresponds to the tail of the fish while heaving and undulation correspond to that of the body. The undulation also corresponds to the surface of the body; for certain fishes. Both numerical and experimental studies in this arena have been reviewed. The present review follows the classification of oscillatory and undulatory motion. We discuss oscillatory motion with emphasis on pitching, heaving, and the combination of these two motions. In undulatory motion, we cover body undulation and surface undulation motion as a propulsive mechanism. We compare and contrast wake signatures, thrust, and propulsive efficiencies for different motion types. A future outlook, which may help researchers to identify open questions, has been provided.</p></div>","PeriodicalId":675,"journal":{"name":"Journal of the Indian Institute of Science","volume":"104 1","pages":"147 - 179"},"PeriodicalIF":2.3,"publicationDate":"2024-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140653704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Computational Hemodynamics in Human Vasculature: A Review on Role of Rheology, Multiphase Flow, and Fluid–Structure Interaction","authors":"Sumant R. Morab,&nbsp;Atul Sharma,&nbsp;Janani S. Murallidharan","doi":"10.1007/s41745-024-00425-9","DOIUrl":"10.1007/s41745-024-00425-9","url":null,"abstract":"<div><p>Efficient and accurate computational model for blood flow dynamics (hemodynamics), is essential for determining optimal treatment strategy, diagnosis, and pathology identification of cardiovascular diseases (CVDs). The focus of the present review paper is to discuss on critical aspects of hemodynamics. Various numerical methods for computational hemodynamics are examined—addressing three key modeling choices. First, the relevance of non-Newtonian hemorheological models in varying vascular conditions is presented. Second, an assessment of single-phase versus multiphase modeling’s validity, for different arterial geometries, is presented. Lastly, investigation on the impact of arterial wall elasticity on blood flow patterns is carried out and a discussion on the necessity of fluid–structure interaction (FSI) model is presented. By surveying diverse scenarios of blood flow modeling, presented in recent literature, it is observed that non-Newtonian behavior significantly impacts severely stenosed arteries or those with low diameters and Womersley numbers, while larger arteries exhibit characteristics similar to Newtonian fluids. Differences between single-phase and multiphase modeling vary with arterial configurations, showcasing notable particle migration effects in curved and branched arteries. Additionally, arterial wall elasticity’s influence varies across scenarios—highlighting the importance of FSI, particularly in diseased states. The article identifies crucial areas for future research to enhance CFD-based hemodynamic modeling, emphasizing the integration of multiphase simulation with non-linear elastic arteries, considering surrounding tissue effects in FSI, innovating patient-specific CAD geometries, and developing faster computational techniques.</p></div>","PeriodicalId":675,"journal":{"name":"Journal of the Indian Institute of Science","volume":"104 1","pages":"13 - 38"},"PeriodicalIF":2.3,"publicationDate":"2024-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140657259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}