2019 Computing in Cardiology (CinC)最新文献_第5页

Early Prediction of Sepsis From Clinical Data Using Single Light-GBM Model 利用单一光- gbm模型从临床数据早期预测脓毒症

2019 Computing in Cardiology (CinC) Pub Date : 2019-09-01 DOI: 10.23919/CinC49843.2019.9005718

S. Chami, K. Tavakolian

引用次数: 6

Machine Learning Improves the Detection of Misplaced V1 and V2 Electrodes During 12-Lead Electrocardiogram Acquisition 机器学习改进了12导联心电图采集过程中V1和V2电极错位的检测

2019 Computing in Cardiology (CinC) Pub Date : 2019-09-01 DOI: 10.23919/CinC49843.2019.9005828

K. Rjoob, R. Bond, D. Finlay, V. Mcgilligan, Stephen Leslie, Aleeha Iftikhar, D. Guldenring, A. Rababah, C. Knoery, A. Peace

{"title":"Machine Learning Improves the Detection of Misplaced V1 and V2 Electrodes During 12-Lead Electrocardiogram Acquisition","authors":"K. Rjoob, R. Bond, D. Finlay, V. Mcgilligan, Stephen Leslie, Aleeha Iftikhar, D. Guldenring, A. Rababah, C. Knoery, A. Peace","doi":"10.23919/CinC49843.2019.9005828","DOIUrl":"https://doi.org/10.23919/CinC49843.2019.9005828","url":null,"abstract":"Electrode misplacement during 12-lead Electrocardiogram (ECG) acquisition can cause false ECG diagnosis and subsequent incorrect clinical treatment. A common misplacement error is the superior placement of V1 and V2 electrodes. The aim of the current research was to detect lead V1 and V2 misplacement using machine learning to enhance ECG data quality to improve clinical decision making. In this particular study, we reasonably assume that V1 and V2 are concurrently superiorly misplaced together. ECGs for 450 patients were extracted from body surface potential maps. Sixteen features were extracted including: morphological, statistical and time-frequency features. Two feature selection approaches (filter method and wrapper method) were applied to find an optimal set of features that provide a high accuracy. To ensure accuracy, six classifiers were applied including: fine tree, coarse tree, bagged tree, Linear Support Vector Machine (LSVM), Quadratic Support Vector Machine (QSVM) and logistic regression. The accuracy of V1 and V2 misplacement detection was 94.3% in the first ICS, 92.7% in the second ICS and 70% in third ICS respectively. Bagged tree was the best classifier in the first, second and third ICS to detect V1 and V2 misplacement.","PeriodicalId":6697,"journal":{"name":"2019 Computing in Cardiology (CinC)","volume":"39 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86159864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Ionic Mechanisms of Triggered Atrial Activity Under a TBX5-driven Regulatory Network 在tbx5驱动的调节网络下触发心房活动的离子机制

2019 Computing in Cardiology (CinC) Pub Date : 2019-09-01 DOI: 10.23919/CinC49843.2019.9005817

Andy C. Y. Lo, Jieyun Bai, P. Gladding, Jichao Zhao

{"title":"The Ionic Mechanisms of Triggered Atrial Activity Under a TBX5-driven Regulatory Network","authors":"Andy C. Y. Lo, Jieyun Bai, P. Gladding, Jichao Zhao","doi":"10.23919/CinC49843.2019.9005817","DOIUrl":"https://doi.org/10.23919/CinC49843.2019.9005817","url":null,"abstract":"Atrial fibrillation (AF) is the most prevalent arrhythmia in clinical practice, yet the pathophysiology by which genetic factors can increase the risk of AF is not well understood. Recently, a multitiered transcriptional network, driven by a T-box transcription factor gene TBX5 and a paired-like homeodomain transcription factor 2 gene PITX2 was discovered. This transcriptional network regulates gene expressions associated with ion channels in a complex fashion, and through mice knockout studies, it was found that reducing the expression of TBX5 altered the gene expressions of certain types of ion channels and generated abnormal depolarizations in the form of early afterdepolarizations, delayed afterdepolarizations, or spontaneous triggered action potentials. To systematically investigate the ionic mechanisms by which impaired TBX5 can lead to AF, we integrated the calcium dynamics of the Grandi et al. model into the Courtemanche-Ramirez-Nattel model. Our model reproduced all forms of abnormal depolarizations observed in TBX5 knockout atrial myocytes. Furthermore, we discovered that the remodeling of the inward-rectifier potassium channel (IK1) and the L- type calcium channel (ICaL), due to impaired TBX5, causes an elevation in the concentration of calcium ([Ca2+]), which reactivates the sodium-calcium exchanger (INaCa) and ICaL to generate abnormal depolarizations.","PeriodicalId":6697,"journal":{"name":"2019 Computing in Cardiology (CinC)","volume":"1 1","pages":"Page 1-Page 4"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88247721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A Unified Pipeline for ECG Imaging Testing 一种统一的心电成像检测流水线

2019 Computing in Cardiology (CinC) Pub Date : 2019-09-01 DOI: 10.23919/CinC49843.2019.9005780

J. Tate, E. V. Dam, W. Good, J. Bergquist, P. V. Dam, R. Macleod

引用次数: 1

Transmural Ventricular Heterogeneities Play a Major Role in Determining T-Wave Morphology at Different Extracellular Potassium Levels 跨壁心室异质性在不同细胞外钾水平下决定t波形态中起主要作用

2019 Computing in Cardiology (CinC) Pub Date : 2019-09-01 DOI: 10.23919/CinC49843.2019.9005944

Hassaan A. Bukhari, Flavio Palmieri, D. Ferreira, M. Potse, J. Ramírez, P. Laguna, C. Sánchez, E. Pueyo

{"title":"Transmural Ventricular Heterogeneities Play a Major Role in Determining T-Wave Morphology at Different Extracellular Potassium Levels","authors":"Hassaan A. Bukhari, Flavio Palmieri, D. Ferreira, M. Potse, J. Ramírez, P. Laguna, C. Sánchez, E. Pueyo","doi":"10.23919/CinC49843.2019.9005944","DOIUrl":"https://doi.org/10.23919/CinC49843.2019.9005944","url":null,"abstract":"End-stage renal disease (ESRD) affects more than 10% of the world population. ESRD patients present impaired potassium homeostasis, which increases the risk for ventricular arrhythmias and sudden cardiac death. Noninvasive estimation of serum potassium, [K+], before the patient experiences serious consequences is of major importance. In this study, we investigated the relationship of [K+] with three T-wave morphological descriptors: the T-wave width (Tw), slope-to-amplitude ratio (TSA) and temporal morphological variability (dw) from ECGs of 12 ESRD patients undergoing hemodialysis and from simulated ECGs. Spearman’s correlation coefficients between the descriptors Tw, TSA and dw and [K+] were –0.5, 0. 8 and 0.65, respectively. These associations were, however, highly patient-dependent. The high inter-individual variability in T-wave morphology, particularly observed at high [K+], was reproduced in the simulations and could be explained by differences in transmural heterogeneities, with 10% variations in the proportion of midmyocardial cells leading to changes larger than 15% in T-wave morphology. In conclusion, T-wave morphological descriptors have the potential to be used as predictors of [K+] in ESRD patients, but their associated inter-individual variability should be taken into account, especially under hyperkalemic conditions.","PeriodicalId":6697,"journal":{"name":"2019 Computing in Cardiology (CinC)","volume":"29 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88276127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 15

Evaluating the Effects of Traditional Persian Music on Nonlinear Parameters of HRV 评价传统波斯音乐对HRV非线性参数的影响

2019 Computing in Cardiology (CinC) Pub Date : 2019-09-01 DOI: 10.23919/CinC49843.2019.9005806

Bahareh Khodabakhshian, S. Moharreri, S. Parvaneh

引用次数: 1

Temporal Stability of Dominant Frequency as Predictor of Atrial Fibrillation Recurrence 优势频率的时间稳定性作为房颤复发的预测因子

2019 Computing in Cardiology (CinC) Pub Date : 2019-09-01 DOI: 10.23919/CinC49843.2019.9005772

Alejandro Costoya-Sánchez, A. Climent, I. Hernández-Romero, A. Liberos, F. Fernández‐Avilés, S. Narayan, F. Atienza, M. Guillem, M. Rodrigo

{"title":"Temporal Stability of Dominant Frequency as Predictor of Atrial Fibrillation Recurrence","authors":"Alejandro Costoya-Sánchez, A. Climent, I. Hernández-Romero, A. Liberos, F. Fernández‐Avilés, S. Narayan, F. Atienza, M. Guillem, M. Rodrigo","doi":"10.23919/CinC49843.2019.9005772","DOIUrl":"https://doi.org/10.23919/CinC49843.2019.9005772","url":null,"abstract":"Catheter ablation is one of the main therapies for restoring sinus rhythm in patients with atrial fibrillation (AF), yet AF termination ratios are far from satisfactory. The goal of this work is to study if temporal stability of dominant frequencies (DFs) of electrograms (EGMs) can be used as predictor of AF recurrence.EGMs were recorded from 29 AF patients using 64-pole basket catheters during the ablation procedure. DFs before ablation were obtained for 4-second overlapping fragments of EGM recordings with a 0.4 s shift, and their temporal stability was evaluated for short-term (between 8 and 12 s) and long-term time intervals (>5 min). Patients were classified as AF (N=15) if sinus rhythm was not maintained in a 12-month post-ablation follow-up, and AF free otherwise (N=14).Significant differences were found in the short-term analysis between AF free and AF patients for the difference between the mode value in DFs (p=0.045), as well as for the long-term analysis for the normalized average between DFs (p=0.028) and the average between DFs (p=0.043). More stable values were found for AF free patients for all statistically significant metrics.Short- and long-term temporal stability of DF values of EGM signals were found to be associated with the 12-month success rate of ablative therapies of AF patients.","PeriodicalId":6697,"journal":{"name":"2019 Computing in Cardiology (CinC)","volume":"88 1","pages":"Page 1-Page 4"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91476731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Maximizing the Reliability of a Full-Automatic ECG-Waveforms Delineating Algorithm Using Extensive ECG Databank 利用广泛的心电数据库实现全自动心电波形描绘算法的可靠性最大化

2019 Computing in Cardiology (CinC) Pub Date : 2019-09-01 DOI: 10.23919/CinC49843.2019.9005577

A. Khawaja

引用次数: 0

A Model of Anatomically Opposed Ischaemia: Revisited 解剖学上对立性缺血模型:重访

2019 Computing in Cardiology (CinC) Pub Date : 2019-09-01 DOI: 10.23919/CinC49843.2019.9005463

P. Johnston

引用次数: 0

Effects of Interpolation on the Inverse Problem of Electrocardiography 插值对心电图反问题的影响

2019 Computing in Cardiology (CinC) Pub Date : 2019-09-01 DOI: 10.23919/CinC49843.2019.9005869

Y. S. Dogrusoz, L. Bear, J. Bergquist, Rémi Dubois, Wilson Good, Robert S. MacLeod, A. Rababah, J. Stoks

{"title":"Effects of Interpolation on the Inverse Problem of Electrocardiography","authors":"Y. S. Dogrusoz, L. Bear, J. Bergquist, Rémi Dubois, Wilson Good, Robert S. MacLeod, A. Rababah, J. Stoks","doi":"10.23919/CinC49843.2019.9005869","DOIUrl":"https://doi.org/10.23919/CinC49843.2019.9005869","url":null,"abstract":"Electrocardiographic Imaging (ECGI) aims to reconstruct electrograms from the body surface potential measurements. Bad leads are usually excluded from the inverse problem solution. Alternatively, interpolation can be applied. This study explores how sensitive ECGI is to different bad-lead configurations and interpolation methods. Experimental data from a Langendorff-perfused pig heart suspended in a human-shaped torso-tank was used. Six different bad lead cases were designed based on clinical experience. Inverse problem was solved by applying Tikhonov regularization i) using the complete data, ii) bad-leads-removed data, and iii) interpolated data, with 5 different methods. Our results showed that ECGI accuracy of an interpolation method highly depends on the location of the bad leads. If they are in the high-potential-gradient regions of the torso, a highly accurate interpolation method is needed to achieve an ECGI accuracy close to using complete data. If the BSP reconstruction of the interpolation method is poor in these regions, the reconstructed electro-grams also have lower accuracy, suggesting that bad leads should be removed instead of interpolated. The inverse-forward method was found to be the best among all interpolation methods applied in this study in terms of both missing BSP lead reconstruction and ECGI accuracy, even for the bad leads located over the chest.","PeriodicalId":6697,"journal":{"name":"2019 Computing in Cardiology (CinC)","volume":"33 1","pages":"Page 1-Page 4"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87258503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6