临床护理研究最新文献

{"title":"Neonatal Brain Abscess: Case Report of 12 Cases and Literature Review","authors":"Nan Peng, Zhimin Chen, Qi Lu","doi":"10.26689/jcnr.v6i6.4451","DOIUrl":"https://doi.org/10.26689/jcnr.v6i6.4451","url":null,"abstract":"Objective: To investigate the etiological characteristics, clinical manifestations, and early identification methods of neonatal brain abscess. Methods: The baseline characteristics, clinical manifestations, and laboratory results of 12 neonatal brain abscess cases were retrospectively analyzed. Results: The clinical manifestations were fever, convulsion, and lethargy. A small number of them had respiratory and circulatory failure. The diagnosis made was based on imaging examination. All 12 cases were confirmed by cranial enhanced computed tomography (CT) or magnetic resonance imaging (MRI). Blood cultures of 9 cases were positive, with Escherichia coli in 6 cases, ?-hemolytic Streptococcus in 1 case, methicillin-resistant Staphylococcus aureus in 1 case, and Enterococcus faecium in 1 case. However, only 3 of them had positive cerebrospinal fluid (CSF) cultures. All the 12 neonates were treated with antibiotic therapy upon admission, with only 3 cases treated with surgery. Among them, 4 recovered and were discharged, while the remaining 8 discontinued their therapy. Conclusion: Escherichia coli is the most common pathogen of neonatal brain abscess in our study. The clinical manifestations of neonatal brain abscess are atypical, and the prognosis is poor. Respiratory and circulatory failure in children with intracranial infection may indicate the presence of brain abscess. For children with suspected brain abscess, cranial enhanced CT or MRI should be performed as soon as possible to make an early diagnosis. The prevention of brain abscess should be prioritized; neonates with sepsis or meningitis should receive prompt and strong antibiotic therapy in an effort to prevent the development of brain abscess.","PeriodicalId":64151,"journal":{"name":"临床护理研究","volume":"15 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41273248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation and Analysis of the Cognition of Menopause in Women Over 40 Years Old","authors":"Meiping Chen, Ting Fang, Lu Chen, Rongrong Huang, Yangfang Tang","doi":"10.26689/jcnr.v6i6.4521","DOIUrl":"https://doi.org/10.26689/jcnr.v6i6.4521","url":null,"abstract":"Objective: To investigate and analyze the cognition of menopause in women over 40 years old. Methods: Using the stratified sampling method, 224 females, age ranging from 40 to 60, from our university staff (Xi’an Medical University) and the surrounding communities were selected, and both online and offline questionnaires were distributed. Results: (1) 224 questionnaires were recovered, with 204 valid questionnaires, among which 100 questionnaires were from our university staff (aged 42–60 years old) and 104 questionnaires from the surrounding communities (aged 40–60 years old); (2) the cognition of menopause among the surveyed population was found to be related to occupation and education level; the cognition of menopause among university staff (76%) was significantly higher than that of the surrounding communities (45.19%); (3) most people were able to accept menopausal hormone therapy; the degree of acceptance among the university staff (80%) was found to be higher than that among the surrounding communities (60.58%). Conclusion: According to the recovered data, women over the age of 40 have less than ideal cognition of menopause, and although the cognitive level of the university staff on menopause was found to be significantly higher than that of the surrounding communities, their cognitive level still requires improvement.","PeriodicalId":64151,"journal":{"name":"临床护理研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49481672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Therapeutic Significance of Arsenite and Thalidomide in Patients with Myelodysplastic Syndrome","authors":"Y. Miao, Ying Gao","doi":"10.26689/jcnr.v6i6.4513","DOIUrl":"https://doi.org/10.26689/jcnr.v6i6.4513","url":null,"abstract":"Objective: To analyze the therapeutic significance of arsenite and thalidomide in patients with myelodysplastic syndrome. Methods: From August 2021 to August 2022, 80 patients with myelodysplastic syndrome were selected and randomly divided into two groups. In the control group, the drug used was thalidomide tablets, whereas in the observation group, the drug used was arsenite and thalidomide. The treatment effect was observed and evaluated. Results: Before treatment, there was no statistical significance in the blood and serological indices between the two groups. After treatment, the observation group showed better blood and serological indices than the control group (P < 0.05). The clinical efficacy of the observation group was 77.5%, while that of the control group was 50.0%. The observation group had significantly better treatment effect (P < 0.05). The incidence of adverse effects in the observation group and the control group was 5.0% and 20.0%, respectively. The observation group had significantly fewer adverse effects (P < 0.05). Conclusion: In the treatment of patients with myelodysplastic syndrome, the use of arsenite on the basis of thalidomide can effectively improve the treatment effect and optimize the levels of various blood and serological indices, with fewer adverse effects and a relatively high safety profile.","PeriodicalId":64151,"journal":{"name":"临床护理研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45144597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meta-Analysis of the Efficacy of Cimetidine in the Treatment of Mumps","authors":"Shiwei Wang, Chenyu Wang","doi":"10.26689/jcnr.v6i6.4479","DOIUrl":"https://doi.org/10.26689/jcnr.v6i6.4479","url":null,"abstract":"Objective: To compare the efficacy of cimetidine and ribavirin in the treatment of mumps by meta-analysis. Methods: Controlled trials of cimetidine and ribavirin in the treatment of mumps were searched through China National Knowledge Infrastructure (CNKI), Wanfang data, Cqvip, Pubmed, The Cochrane Library and EMBase databases up to September 2022. The effective rate, the time of swelling regression in parotid gland area and the rate of adverse reactions were analyzed by Review Manager 5.3 software. Results: The final 10 articles included 920 children, including 427 in the trial group and 447 in the control group. Meta analysis showed that the effective rate of cimetidine in the treatment of mumps was higher than that of ribavirin in routine treatment, with a statistically significant difference (odds ratio [OR] = 5.2, P < 0.00001); The time of swelling regression was statistically significant (OR = -1.28, P < 0.00001); The difference of adverse reaction rate was not statistically significant (OR = 0.73, P = 0.62). Conclusions: Compared with ribavirin, cimetidine is more effective in the treatment of mumps, with shorter swelling regression time without increases of adverse reactions.","PeriodicalId":64151,"journal":{"name":"临床护理研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44131841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Observation on the Clinical Effect of Stereotactic Body Radiotherapy in Patients with Oligometastatic Tumors","authors":"Gaofei Zhang, Long Jin, Xin Chen, Hui Gao, Shaojun Ma, Zhuo Wu","doi":"10.26689/jcnr.v6i6.4429","DOIUrl":"https://doi.org/10.26689/jcnr.v6i6.4429","url":null,"abstract":"Objective: To observe the efficacy and safety of stereotactic body radiotherapy (SBRT) in the treatment of extracranial oligometastases. Method: A retrospective analysis of 70 patients with extracranial oligometastasis of malignant tumors who underwent SBRT in our hospital (Shaanxi Provincial People’s Hospital) from January 2019 to December 2021 with ? 5 metastases, ?3 metastatic organs, and metastases with diameters of ? 5 cm. According to the clinical data of patients, the dose-fractionation mode of SBRT is mainly determined according to the pathology of the primary tumor, the location of the metastatic tumor, and the important structures around the tumor. The local control, survival and adverse reactions were observed. Results: A total of 219 oligometastatic lesions in 70 patients were treated with SBRT. The median follow-up time was 24 months (12–40 months). The local control rate (LCR) of all target lesions assessed 3 months after radiotherapy was 94.1%; the 1-, 2-, and 3-year LCRs were 88.6%, 74.6%, and 64.9%, respectively. The median progression-free survival (PFS) was 11.8 months (95% CI, 8.9–14.7 months), and the 1- and 2-year PFS rates were 48.6% and 32.6%, respectively; the median overall survival (OS) was 31.9 month (95% CI 26.0-37.8 months), the 1-year OS rate was 84.3%. The local control time, PFS, and OS of patients with metastases ? 3 cm were significantly better than those with metastases > 3 cm, and the differences were statistically significant (P < 0.05). Acute adverse reactions after SBRT treatment in oligometastatic patients were mainly bone marrow suppression and gastrointestinal reactions, with incidence rates of 48.98% and 30.61%, respectively; chronic adverse reactions were mainly pain (bone, muscle), radiation enteritis, and radiation pneumonitis, with incidence rates of 38.57%, 30.00%, and 24.29%, respectively. The treatment-related adverse reactions were mainly grade 1, which were all improved after symptomatic treatment, except for one patient with bone metastases from lung cancer who had grade 4 myelosuppression. No grade 4 or 5 adverse events occurred in the other patients. Conclusion: The application of SBRT in the treatment of extracranial oligometastases is safe, effective, and has high tolerability.","PeriodicalId":64151,"journal":{"name":"临床护理研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42167177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy Observation of Pre-Excitation Regimen in the Treatment of Refractory Relapsed Acute Non-Lymphocytic Leukemia","authors":"Y. Miao","doi":"10.26689/jcnr.v6i6.4440","DOIUrl":"https://doi.org/10.26689/jcnr.v6i6.4440","url":null,"abstract":"Objective: To explore the clinical effect of applying the pre-excitation regimen in the treatment of patients with refractory relapsed acute non-lymphocytic leukemia (ANLL). Methods: This research work was carried out in our hospital (Shaanxi Provincial People’s Hospital) from September 2021 to September 2022. A total of 50 cases were selected for this study, and all were given a pre-excitation treatment plan, mainly low-dose cytarabine, aclarithromycin, etoposide, granulocyte colony-stimulating factor, and more were implemented. The clinical intervention effect was then analyzed. Results: Among the 50 patients in this study, the results showed that the treatment was very effective for 22 cases, accounting for 44.00%; effective for 14 cases, accounting for 28.00%; and ineffective for 14 cases, accounting for 28.00%. The total rate of effectiveness was 72.00%. The hematopoietic system adverse reactions of the patients were mainly bone marrow suppression. All 50 patients had different degrees of blood count decline, among which some patients’ neutrophils were less than 0.5×109 /L. The median time was 7 days. Among them, 25 patients had infection problems, the incidence rate was 50.00%, the patient’s platelet count PLT < 20 × 109/L, and the median time was 10 days. At the same time, among the 50 patients in this study, 34 (68.00%) patients had symptoms such as loss of appetite, nausea, vomiting, and fatigue, 17 (34.00%) patients showed hair loss, mildly elevated transaminases were observed in 8 (16.00%) patients, and 11 (22.00%) patients had muscle soreness. Conclusion: In the treatment of patients with refractory complex acute non-lymphocytic leukemia, the application of pre-excitation regimen has a significant effect, which can improve the adverse symptoms of patients, reduce the incidence of adverse reactions, and promote the recovery of patients.","PeriodicalId":64151,"journal":{"name":"临床护理研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43215010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patients with Shoulder Dysfunction After Mastectomy Can Benefit from Nurse-Assisted Home-Based Range of Motion Exercises","authors":"Waqas Ahmed, F. Afzal","doi":"10.26689/jcnr.v6i6.4382","DOIUrl":"https://doi.org/10.26689/jcnr.v6i6.4382","url":null,"abstract":"Background: Shoulder dysfunction is very common after mastectomy, and there is also less follow-up for physiotherapy services among patients with mastectomy. Objective: A study was conducted to determine the role of nurse-assisted home-based range of motion (ROM) exercises in patients with shoulder dysfunction after mastectomy. Methods: A pre- and post-interventional study design was used to collect data from 30 post-mastectomy patients. The subjects were selected on a voluntary basis. Informed consent was obtained from post-mastectomy patients who were discharged from different oncology hospitals in Pakistan prior to their inclusion in this study. After obtaining a baseline measurement, the patients were supervised with nurse-assisted ROM exercises at home. The nurse-assisted home-based ROM exercise program was designed for such patients, and the patients were followed-up for up to 1 month. The total duration of the study was 1 year from August 2015 to August 2016. Post-intervention measurement was performed at the patients’ home. The difference in terms of pain reduction and ROM improvement at the shoulder joint was recorded using goniometric measurements and the 100 mm visual analogue scale (VAS). Results: The mean age of the 30 subjects was 39.83 ± 5.89. The mean ROM of shoulder flexion before the exercise program was 106.03°, which improved to 133.93° after 1 month of the exercise program. The mean ROM of shoulder abduction before treatment was 94.83°, which improved to 127.13° after 1 month of supervised exercise program. The mean ROM of shoulder rotation before the exercise program was 127.53°, which improved to 152.03° after 1 month of the exercise program. Conclusion: The nurse-assisted home-based shoulder ROM exercise program is effective in terms of improving the range of motion and reducing pain at the shoulder joint in post-mastectomy patients.","PeriodicalId":64151,"journal":{"name":"临床护理研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48888520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Efficacy of Western Medicine Combined with Chinese Medicine for Pelvic Inflammatory Disease (Damp-Heat and Stasis Type)","authors":"Yao Chen, Yu Cao, Huifang Li","doi":"10.26689/jcnr.v6i6.4345","DOIUrl":"https://doi.org/10.26689/jcnr.v6i6.4345","url":null,"abstract":"Objective: This study was undertaken to evaluate the clinical efficacy of Western medicine combined with Chinese medicine for pelvic inflammatory disease (damp-heat and stasis type). Methods: Seventy-four patients who were diagnosed with pelvic inflammatory disease (damp-heat and stasis type) by our hospital during July 2021 to July 2022 were randomized into two groups: the participants in the control group received conventional Western medicine treatment, and the participants in the study group received Western medicine combined with Chinese medicine. Results: After treatment, the total effectiveness of the control group (72.98%) was significantly lower than that of the study group (94.59%), (P < 0.05); the whole blood viscosity high cut, whole blood viscosity low cut, fibrinogen and plasma viscosity of the control group were all lower than those of the study group (P < 0.05); the levels of CRP, IL-6, and TNF-? in the control group were higher and IL-2 levels in the control group were lower than those in the study group (P < 0.05). Conclusion: Western medicine combined with Chinese medicine is more effective in curing damp-heat and stasis-type pelvic inflammatory disease by improving the blood rheological indexes and lowering the level of inflammatory factors.","PeriodicalId":64151,"journal":{"name":"临床护理研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47866957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of Influencing Factors of Preeclampsia on Postpartum Hemorrhage","authors":"Zhen Han, Ligong Zhu","doi":"10.26689/jcnr.v6i6.4367","DOIUrl":"https://doi.org/10.26689/jcnr.v6i6.4367","url":null,"abstract":"Postpartum hemorrhage is a serious complication of preeclampsia. The main influencing factors of Preeclampsia on postpartum hemorrhage include vascular disease, trophoblast differentiation and infiltration disorder, the influence of antispasmodic, sedative and antihypertensive drugs, the incidence of hypertensive disorder complicating pregnancy related to calcium deficiency, coagulation dysfunction, and decreased blood volume during pregnancy. In recent years, postpartum hemorrhage has been the leading cause of maternal death in the world. Therefore, it is critical to understand the influencing factors of preeclampsia on postpartum hemorrhage. Based on the research and guidelines of preeclampsia and postpartum hemorrhage in recent years, this paper analyzes the influencing factors of preeclampsia on postpartum hemorrhage, and provides new ideas for clinical reduction of postpartum hemorrhage.","PeriodicalId":64151,"journal":{"name":"临床护理研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49506084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nursing Effect of Pulmonary Rehabilitation in Patients with Chronic Obstructive Pulmonary Disease","authors":"Qiming Cheng, Fei Lai, Liu Yang, Shuang Long, Ruyang Song","doi":"10.26689/jcnr.v6i6.4506","DOIUrl":"https://doi.org/10.26689/jcnr.v6i6.4506","url":null,"abstract":"Objective: To study the effect of pulmonary rehabilitation nursing in nursing of patients with chronic obstructive pulmonary disease (COPD). Methods: 30 cases of experimental subjects, diagnosed with COPD, were included in the observation group with pulmonary rehabilitation nursing, while the control group received routine nursing, and the data between the groups were compared. Results: After nursing, the observation group showed significantly improved lung function, higher nursing satisfaction, 6-minute walking test (6WMT), World Health Organization Quality of Life (WHOQOL-BREF) score, and self-care ability score, compared to the control group, with P < 0.05, indicating a statistical difference. Conclusion: Pulmonary rehabilitation nursing is applied in the nursing of COPD patients with ideal effect.","PeriodicalId":64151,"journal":{"name":"临床护理研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47850711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}