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2008 2nd International Conference on Bioinformatics and Biomedical Engineering最新文献

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Study on the Apoptosis Effect Induced by Isothiocyanates in Broccoli on Human Gastric Adenoma Cells (SGC-7901) 西兰花异硫氰酸酯诱导人胃腺瘤细胞(SGC-7901)凋亡的研究
2008 2nd International Conference on Bioinformatics and Biomedical Engineering Pub Date : 2008-12-18 DOI: 10.1109/FBIE.2008.50
Z. Xiang, Ji Yu-bin, Ji Chen-feng, Yu Lei, L. Lang
{"title":"Study on the Apoptosis Effect Induced by Isothiocyanates in Broccoli on Human Gastric Adenoma Cells (SGC-7901)","authors":"Z. Xiang, Ji Yu-bin, Ji Chen-feng, Yu Lei, L. Lang","doi":"10.1109/FBIE.2008.50","DOIUrl":"https://doi.org/10.1109/FBIE.2008.50","url":null,"abstract":"To investigate the pro-apoptosis effect of isothiocyanates(ITCS) on human gastric adenoma cells SGC- 7901 and its mechanism. METHODS: SGC-7901 was treated with different concentrations of ITCS. MTT assay was used to evaluate the influence of ITCS on cell proliferation. Flow cytometry was used to test reactive oxygen species (ROS) levels, intracellular mitochondrial transmembrane potential (Deltapsim), and hypodiploid apoptosis peak in both SGC-7901. RESULTS: ITCS obviously inhibited proliferation of SGC-7901 cells. When treated with 0, 15, 30, 60, 120, 240 mug /mL of ITCS for 24 h, intracellular ROS levels of SGC-7901 were (1.6 plusmn 0.5)%, (2.0 plusmn 0.3)%, (5.5 plusmn0.4)%, (25.8 plusmn1.4)%, (83.7 plusmn 1.2)% and (97.4 plusmn 4.2)%, respectively; and Deltapsim were (98.6 plusmn4.3)%, (98.4 plusmn 4.8)%, (95.7 plusmn 5.4)%, (92.6 plusmn 4.0)%, (74.0 plusmn 5.6)% and (63.7 plusmn4.0)%, respectively; when treated with 0, 60, 120, 240 mug /mL of ITCS for 48 h, cell apoptotic rates of SGC-7901 were (4.3 plusmn1.6)%, (9.1 plusmn 3.8)%, (20.1 plusmn 4.2)% and (55.4 plusmn 4.9)%, respectively. CONCLUSIONS: ITCS generates ROS in both SGC-7901, which causes mitochondrial membrane permeabilization and Deltapsim decrease, therefore, leads to apoptosis.","PeriodicalId":6399,"journal":{"name":"2008 2nd International Conference on Bioinformatics and Biomedical Engineering","volume":"1 1","pages":"939-942"},"PeriodicalIF":0.0,"publicationDate":"2008-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76843343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Temporal Changes in Landscape of Zhalong Wetland 扎龙湿地景观的时空变化
2008 2nd International Conference on Bioinformatics and Biomedical Engineering Pub Date : 2008-06-03 DOI: 10.1109/ICBBE.2008.603
Yuhong Zhang, Liying Su, Shuqing Zhang, Jing Ning
{"title":"Temporal Changes in Landscape of Zhalong Wetland","authors":"Yuhong Zhang, Liying Su, Shuqing Zhang, Jing Ning","doi":"10.1109/ICBBE.2008.603","DOIUrl":"https://doi.org/10.1109/ICBBE.2008.603","url":null,"abstract":"We studied the landscape changes in Zhalong Wetland by using satellite-images and GIS technique. We analyzed the temporal and spatial changes of in the wetlands. Our results shows that there several changes have been happening in the wetland, such as water distribution pattern, increasing alkaline land cover, and less vegetation cover. These trends continue could change the integrity of ecosystem, reduce bio-diversity and ecological functions of the wetland system; therefore, management efforts should be strengthened and a series of mechanism of wetlands restoration need to be set up.","PeriodicalId":6399,"journal":{"name":"2008 2nd International Conference on Bioinformatics and Biomedical Engineering","volume":"64 1","pages":"4426-4430"},"PeriodicalIF":0.0,"publicationDate":"2008-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80018168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Yet Another Scenario of Pattern Formation: Interpretation of Position Information 模式形成的另一个场景:位置信息的解释
2008 2nd International Conference on Bioinformatics and Biomedical Engineering Pub Date : 2008-06-03 DOI: 10.1109/ICBBE.2008.203
Yue Ma, K. Yoshikawa
{"title":"Yet Another Scenario of Pattern Formation: Interpretation of Position Information","authors":"Yue Ma, K. Yoshikawa","doi":"10.1109/ICBBE.2008.203","DOIUrl":"https://doi.org/10.1109/ICBBE.2008.203","url":null,"abstract":"During the development process, how the position information is determined is one of the most important issue. We propose a scenario that the pattern are generated from a class of discrete reaction-diffusion system, in which the character of every single cell varies according to space distribution. Using the key feature of wave propagation failure, we can observe and even design various pattern. It takes a different scenario from the well known Turing structure.","PeriodicalId":6399,"journal":{"name":"2008 2nd International Conference on Bioinformatics and Biomedical Engineering","volume":"73 1","pages":"828-831"},"PeriodicalIF":0.0,"publicationDate":"2008-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76925702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study on Improvement of Pollutants Removal Efficiency by Backside Aeration in Wavy Subsurface-Flow Constructed Wetland 波浪潜流人工湿地背面曝气提高污染物去除效率的研究
2008 2nd International Conference on Bioinformatics and Biomedical Engineering Pub Date : 2008-06-03 DOI: 10.1109/ICBBE.2008.1084
Ren Yong-zheng, Zhang Beiping, Hai Ben-zeng
{"title":"Study on Improvement of Pollutants Removal Efficiency by Backside Aeration in Wavy Subsurface-Flow Constructed Wetland","authors":"Ren Yong-zheng, Zhang Beiping, Hai Ben-zeng","doi":"10.1109/ICBBE.2008.1084","DOIUrl":"https://doi.org/10.1109/ICBBE.2008.1084","url":null,"abstract":"Lower removal rates of ammonium nitrogen in the constructed wetlands were mainly caused by the lack of dissolved oxygen (DO). The traditional wavy subsurface-flow constructed wetland was modified to install an aeration tube in the third wave interval to increase DO and the nitrification rates within the constructed wetlands. As most COD had been removed in the second wave interval, nitrifying bacteria became dominant in the third wave interval, which led to the nitrification extent to reach more than 95%. The ability to endure the impact of hydraulic loading was also enhanced. The hydraulic loading of wetlands was raised up to 0.8m<sup>3</sup>/m<sup>2</sup>ldrd<sup>-1</sup>, with a COD organic loading of 56-112 g COD/m<sup>2</sup>ldrd<sup>-1</sup>, and ammonium loading rates about 20-28 g NH<sub>4</sub> <sup>+</sup>-N/m<sup>2</sup>ldrd<sup>-1</sup>. These values were much higher than those reported of nitrification in constructed wetlands.","PeriodicalId":6399,"journal":{"name":"2008 2nd International Conference on Bioinformatics and Biomedical Engineering","volume":"46 1","pages":"3010-3013"},"PeriodicalIF":0.0,"publicationDate":"2008-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86143987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Repaire of Large Segmental Bone Defects by Marrow Stromal Cells Transplant with Demineralized Bone Matrix 脱矿化骨基质骨髓间质细胞移植修复大节段骨缺损
2008 2nd International Conference on Bioinformatics and Biomedical Engineering Pub Date : 2008-06-03 DOI: 10.1109/ICBBE.2008.255
Zhao Xie, F. Luo, Jian-Zhong Xu, Shi-wu Dong
{"title":"Repaire of Large Segmental Bone Defects by Marrow Stromal Cells Transplant with Demineralized Bone Matrix","authors":"Zhao Xie, F. Luo, Jian-Zhong Xu, Shi-wu Dong","doi":"10.1109/ICBBE.2008.255","DOIUrl":"https://doi.org/10.1109/ICBBE.2008.255","url":null,"abstract":"The aim of this study was to determine the healing potential of large segmental bone defects using tissue-engineered constructs in a large animal model before it can be introduced into a clinical trial. Isolated Autologous marrow stromal cells (aMSCs) were cultured in vitro, then seeded into allogenic demineralized bone matrix (aDBM) and co-cultivated for 7 days to construct DBM-MSCs complex. 24 goats were randomly divided into three groups (8 in each), on which 3 cm diaphyseal femoral defects were created unilaterally and subsequently filled with the DBM-MSCs complex, DBM alone and untreated control, respectively. A semiquantitative grading score was applied for radiological analysis after 12 weeks and 24 weeks. DBM-MSCs group increased the radiological scoring and biomechanical strength significantly and superiored over DBM only group. The animals in DBM-MSCs group total bone regeneration was observed in X-ray, whereas most of animal of DBM only group showed partial bone regeneration, while untreated showed no defect healing. Bone regeneration of DBM-MSCs group was histologically better than in DBM only controls and failed in untreated group. In summary, this study confirmed that the goat critical size defect was appropriate in size to produce large defect nonunions model, and our results strongly encourage the application of the transplantation of bone marrow stromal cells within demineralized bone matrix for bone regeneration of large segmental bone defects.","PeriodicalId":6399,"journal":{"name":"2008 2nd International Conference on Bioinformatics and Biomedical Engineering","volume":"91 1","pages":"1042-1045"},"PeriodicalIF":0.0,"publicationDate":"2008-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86812099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Hemodynamics Minimal Model for the Cerebral Circulation of Willis Based on Graph Theory 基于图论的Willis脑循环血流动力学最小模型
2008 2nd International Conference on Bioinformatics and Biomedical Engineering Pub Date : 2008-06-03 DOI: 10.1109/ICBBE.2008.778
Yunan Hu, Jinxue Sui, Li Yang, Zhen Hua
{"title":"A Hemodynamics Minimal Model for the Cerebral Circulation of Willis Based on Graph Theory","authors":"Yunan Hu, Jinxue Sui, Li Yang, Zhen Hua","doi":"10.1109/ICBBE.2008.778","DOIUrl":"https://doi.org/10.1109/ICBBE.2008.778","url":null,"abstract":"Based on system's viewpoint, the cerebral circulation of Willis is fluid network system that is composed of four entrances and three communicating arteries. Using lumped parameter approximations of incompressible Navier-Stokes equations and the graph theory of the circuit network, a nonlinear minimal model is established for fluid network systems. This model provides the basis for the entire cerebral circulation network's parameter computation and survey, also provides treatment reference for branch blood flow and pressure control.","PeriodicalId":6399,"journal":{"name":"2008 2nd International Conference on Bioinformatics and Biomedical Engineering","volume":"1 1","pages":"1796-1799"},"PeriodicalIF":0.0,"publicationDate":"2008-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74311917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Effects of Zinc and Chromium Stresses on Quality of Rice Grain 锌、铬胁迫对稻米品质的影响
2008 2nd International Conference on Bioinformatics and Biomedical Engineering Pub Date : 2008-05-16 DOI: 10.1109/ICBBE.2008.612
Xuemei Zhu, Lijin Lin, Ji-rong Shao, Yuanxiang Yang, Xiaojun Jiang, Qingsong Zhang
{"title":"Effects of Zinc and Chromium Stresses on Quality of Rice Grain","authors":"Xuemei Zhu, Lijin Lin, Ji-rong Shao, Yuanxiang Yang, Xiaojun Jiang, Qingsong Zhang","doi":"10.1109/ICBBE.2008.612","DOIUrl":"https://doi.org/10.1109/ICBBE.2008.612","url":null,"abstract":"To reveal the impact of zinc and chromium stresses on the quality of rice grain, a set of experiments were conducted where the quality of rice grain was studied across different concentrations of zinc and chromium in the soil. The results revealed many dependencies. For example, the changes in milling quality and the shape of rice grain were minimal. However, increasing concentrations of zinc and chromium in the soil both produced higher rates of chalky rice. Amylose content was found to increase at lower concentrations of zinc in the soil, yet higher concentrations of chromium also produced higher amylose content. The content of crude protein in rice grain showed an increasing trend with increasing concentrations of either zinc or chromium. Finally, a positive correlation was found between the concentration of zinc in the soil and the concentrations of both zinc and chromium in the rice grain. Whereas increasing concentrations of chromium in the soil yielded higher chromium content in the rice, but had no measurable impact on zinc content.","PeriodicalId":6399,"journal":{"name":"2008 2nd International Conference on Bioinformatics and Biomedical Engineering","volume":"51 1","pages":"4475-4479"},"PeriodicalIF":0.0,"publicationDate":"2008-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73639140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
A Simplified Multivariate Markov Chain Model for the Construction and Control of Genetic Regulatory Networks 遗传调控网络构建与控制的简化多元马尔可夫链模型
2008 2nd International Conference on Bioinformatics and Biomedical Engineering Pub Date : 2008-05-16 DOI: 10.1109/ICBBE.2008.138
Shuqin Zhang, W. Ching, Y. Jiao, Ling-Yun Wu, R.H. Chan
{"title":"A Simplified Multivariate Markov Chain Model for the Construction and Control of Genetic Regulatory Networks","authors":"Shuqin Zhang, W. Ching, Y. Jiao, Ling-Yun Wu, R.H. Chan","doi":"10.1109/ICBBE.2008.138","DOIUrl":"https://doi.org/10.1109/ICBBE.2008.138","url":null,"abstract":"The construction and control of genetic regulatory networks using gene expression data is an important research topic in bioinformatics. Probabilistic Boolean Networks (PBNs) have been served as an effective tool for this purpose. However, PBNs are difficult to be used in practice when the number of genes is large because of the huge computational cost. In this paper, we propose a simplified multivariate Markov model for approximating a PBN. The new model can preserve the strength of PBNs and at the same time reduce the complexity of the network and therefore the computational cost. We then present an optimal control model with hard constraints for the purpose of control/intervention of a genetic regulatory network. Numerical experimental examples based on the yeast data are then given to demonstrate the effectiveness of our proposed model and control policy.","PeriodicalId":6399,"journal":{"name":"2008 2nd International Conference on Bioinformatics and Biomedical Engineering","volume":"10 1","pages":"569-572"},"PeriodicalIF":0.0,"publicationDate":"2008-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75410279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Neural Signal Recording and Transmission System with 3-D Silicon Microelectrode Arrays 三维硅微电极阵列神经信号记录与传输系统
2008 2nd International Conference on Bioinformatics and Biomedical Engineering Pub Date : 2008-05-16 DOI: 10.1109/ICBBE.2008.852
Li Xingfei, Sun Fei, L. Hongyu, Sha Qiuyun
{"title":"Neural Signal Recording and Transmission System with 3-D Silicon Microelectrode Arrays","authors":"Li Xingfei, Sun Fei, L. Hongyu, Sha Qiuyun","doi":"10.1109/ICBBE.2008.852","DOIUrl":"https://doi.org/10.1109/ICBBE.2008.852","url":null,"abstract":"In this paper, we present a new kind of neural signal recording and stimulating system consisting of active microelectrode arrays, signal conditioning circuits and user interface. The system is designed to record from up to 32 sites of nervous system in 3-D dimension with good signal-to-noise ratio (SNR) and DC offset stabilization, which gives neurophysiologists better tools to understand neural action and the human being's cognizance process. The method of stimulate nerves with microelectrode can cure some difficult symptoms like infantile paralysis, parkinsonism and epilepsy. The rat experiment has done and the acquired signal is ideal. This proves the feasibility of the system.","PeriodicalId":6399,"journal":{"name":"2008 2nd International Conference on Bioinformatics and Biomedical Engineering","volume":"11 1","pages":"2091-2094"},"PeriodicalIF":0.0,"publicationDate":"2008-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75648081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Local SPECT Reconstruction with Non-Uniform Attenuation 非均匀衰减局部SPECT重建
2008 2nd International Conference on Bioinformatics and Biomedical Engineering Pub Date : 2008-05-16 DOI: 10.1109/ICBBE.2008.980
Bing Liu, Junhai Wen, Xin Li, Xu Meng
{"title":"Local SPECT Reconstruction with Non-Uniform Attenuation","authors":"Bing Liu, Junhai Wen, Xin Li, Xu Meng","doi":"10.1109/ICBBE.2008.980","DOIUrl":"https://doi.org/10.1109/ICBBE.2008.980","url":null,"abstract":"SPECT (single photon emission computed tomography) is a tomography technique that can greatly show information about the metabolic activity and improve clinical diagnosis. In 2000, R Novikov discovered the explicit SPECT reconstruction formula with non-uniform attenuation. Based on R. Novikov's reconstruction formula, we had derived a wavelet based SPECT reconstruction algorithm. Like the conventional CT reconstruction algorithm, these algorithms require full projection data in order to reconstruct the image even though reconstruction area is a small part of the body. In this paper, we present a wavelet based local SPECT reconstruction algorithm with non-uniform attenuation, which only need the local projection data from the region of interest (ROI), this means smaller detector required and reconstruction time would become shorter.","PeriodicalId":6399,"journal":{"name":"2008 2nd International Conference on Bioinformatics and Biomedical Engineering","volume":"39 1","pages":"2586-2589"},"PeriodicalIF":0.0,"publicationDate":"2008-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75792984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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