2010 4th International Conference on Bioinformatics and Biomedical Engineering最新文献_第9页

Evaluation of Groundwater Environment Carrying Capacity Based on Catastrophe Theory 基于突变理论的地下水环境承载力评价

2010 4th International Conference on Bioinformatics and Biomedical Engineering Pub Date : 2010-06-18 DOI: 10.1109/ICBBE.2010.5515459

Nanxiang Chen, Ji-hong Qu, Jianxin Xu, Zhi-ping Li, Li Yang

{"title":"Evaluation of Groundwater Environment Carrying Capacity Based on Catastrophe Theory","authors":"Nanxiang Chen, Ji-hong Qu, Jianxin Xu, Zhi-ping Li, Li Yang","doi":"10.1109/ICBBE.2010.5515459","DOIUrl":"https://doi.org/10.1109/ICBBE.2010.5515459","url":null,"abstract":"Evaluation of groundwater environment carrying capacity is a multi-objective, multi-criteria and multi-level comprehensive issue. Evaluation index system of groundwater environment carrying capacity was built and divided into some subsystems in accordance with each index's inherent stratification link. Every index's effect on carrying capacity system was obtained by normalization operations catastrophe-based, so the ultimate value of fuzzy membership function catastrophe-based, which explains the groundwater environment carrying capacity, can been calculated from the lowermost layer to the topmost layer. The method was applied to evaluate groundwater environment carrying capacity in People's Victory Canal Irrigation District. In order to reveal outer and inner factor's effect to groundwater system, evaluation index system was divided into 3 kinds of top-level subsystem, i.e., the development and utilization degree of water resources, economy society and eco-environment subsystem, which include 17 kinds of bottom-level sub-index. The comprehensive evaluation result catastrophe-based is 0.9282, 0.9212, and 0.9150 in 1995, 2000, and 2005 separately, and groundwater environment carrying capacity are all weak and shows a downtrend year by year along with rapid economy expanding. The result reveals that it is a fact that groundwater resources and eco-environment in irrigation district is increasingly prominent. As it is not necessary to define the weight of evaluation indexes in dynamic fuzzy comprehensive evaluation model catastrophe-based, subjectivity of the decision-making has been reduced. The examples show that the method in this paper is reasonable and feasible by fuzzy comprehensive evaluation method's validation.","PeriodicalId":6396,"journal":{"name":"2010 4th International Conference on Bioinformatics and Biomedical Engineering","volume":"25 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2010-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82050836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Safety Early-Warning Model for Coal Mines Based on Artificial Neural Network 基于人工神经网络的煤矿安全预警模型

2010 4th International Conference on Bioinformatics and Biomedical Engineering Pub Date : 2010-06-18 DOI: 10.1109/ICBBE.2010.5518062

Q. Zeng, Xu Wang

引用次数: 0

Effects of Sub-Chronic Aluminum Intoxication on Apoptosis of Cerebrum Neurocytes in Chickens: Preliminary Study on Effect of Aluminum Accumulation on Nervous System in Chickens 亚慢性铝中毒对鸡大脑神经细胞凋亡的影响:铝蓄积对鸡神经系统影响的初步研究

2010 4th International Conference on Bioinformatics and Biomedical Engineering Pub Date : 2010-06-18 DOI: 10.1109/ICBBE.2010.5515279

Hao Sun, Yan-fei Li, Chong-wei Hu, Y. She, Lingyu Gao

{"title":"Effects of Sub-Chronic Aluminum Intoxication on Apoptosis of Cerebrum Neurocytes in Chickens: Preliminary Study on Effect of Aluminum Accumulation on Nervous System in Chickens","authors":"Hao Sun, Yan-fei Li, Chong-wei Hu, Y. She, Lingyu Gao","doi":"10.1109/ICBBE.2010.5515279","DOIUrl":"https://doi.org/10.1109/ICBBE.2010.5515279","url":null,"abstract":"The model of different level's sub-chronic aluminum intoxication in chickens was established by continuous peritoneal injection of fixed volume and different gradient aluminum trichloride (AlCl3). The apoptosis of cerebrum neurocytes was detected by agarose gel electrophor-esis, AO/EB double fluorescent staining and flow cytometry. The results showed that: (1) The typical apoptosis and necrosis of cerebrum neurocytes were observed in the fluorescence microscope, and the apoptotic index in the experimental groups was significantly higher than that in the control groups (P<0.01), which increased along with increase of aluminum concentration; (2) The number of cerebrum neurocytes increased in G0/G1 phases, while decreased in G2/M and S phases. The cell proliferation index decreased and apoptosis rate increased, which were significantly different compared with the control ones (P<0.01); (3) The typical DNA Ladder-shaped of cerebrum neurocytes of chickens in experimental groups was displayed by agarose gel electropho- resis. The results indicated that aluminum can cause the DNA damage, inhibite the proliferation and induce the apoptosis of cerebrum cell.","PeriodicalId":6396,"journal":{"name":"2010 4th International Conference on Bioinformatics and Biomedical Engineering","volume":"72 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2010-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85763469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Synthesis and Performance Research of Biodegradable Modified Polyaspartic Acid 可生物降解改性聚天冬氨酸的合成及性能研究

2010 4th International Conference on Bioinformatics and Biomedical Engineering Pub Date : 2010-06-18 DOI: 10.1109/ICBBE.2010.5516477

Yu-hua Gao, Zhenfa Liu, Lihui Zhang, Yanji Wang

引用次数: 9

Acute Effects of Oil Dispersant and No.0 Diesel Oil on Sea Urchin, Hemicentrotus pulcherrimus 油类分散剂和0号柴油对海胆的急性影响

2010 4th International Conference on Bioinformatics and Biomedical Engineering Pub Date : 2010-06-18 DOI: 10.1109/ICBBE.2010.5515278

F. Lv, D. Xiong

{"title":"Acute Effects of Oil Dispersant and No.0 Diesel Oil on Sea Urchin, Hemicentrotus pulcherrimus","authors":"F. Lv, D. Xiong","doi":"10.1109/ICBBE.2010.5515278","DOIUrl":"https://doi.org/10.1109/ICBBE.2010.5515278","url":null,"abstract":"The acute toxicities of water-accomodated fractions(WAFs) of No.0 diesel oil and dispersed water-accomodated fractions(dis-WAFs) on sea urchin, Hemicentrotus pulcherrimus were studied and tissue-specific response against oxidative stress were analyzed in this paper. Dispersed WAFs of No.0 diesel oil was found to be more toxic to sea urchin than WAFs. 24, 48, 72, 96-h EC50 values of WAFs were 18.2 mg/L, 15.5 mg/L, 11.5 mg/L and 9.5mg/L respectively; and those of dis-WAFs were 11.7 mg/L, 9.1mg/L, 7.4mg/L and 5.1mg/L respectively. GC-MS analysis showed that more aromatic compounds dissolve into the sea water after adding chemical dispersant to oil. Followed by the exposure time, superoxide dismutase (SOD), catalase(CAT) and glutathione S-transferase(GST) activities in intestine were induced first, and then decreased gradually. The dose-effect relationship occurrs in 13d samples; SOD , CAT and GST activities of all concentration groups were recovered to the corresponding control level after 11d recovery experiment. The activities first increased in short time at low concentration of WAFs, and was significantly depressed at high concentrations. SOD, CAT and GST had important roles in detoxification, and showed great potential as biomarkers for benthic marine oil pollution.","PeriodicalId":6396,"journal":{"name":"2010 4th International Conference on Bioinformatics and Biomedical Engineering","volume":"18 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2010-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86033992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

The Dynamic Study in Astrocytes and Cytokines in a Rat Model of Vascular Dementia by Xiongma Dropping Pill 雄马滴丸对血管性痴呆模型大鼠星形细胞和细胞因子的动态研究

2010 4th International Conference on Bioinformatics and Biomedical Engineering Pub Date : 2010-06-18 DOI: 10.1109/ICBBE.2010.5518136

Ying Zhao, Lin Liu, Dan Li, H. Teng

{"title":"The Dynamic Study in Astrocytes and Cytokines in a Rat Model of Vascular Dementia by Xiongma Dropping Pill","authors":"Ying Zhao, Lin Liu, Dan Li, H. Teng","doi":"10.1109/ICBBE.2010.5518136","DOIUrl":"https://doi.org/10.1109/ICBBE.2010.5518136","url":null,"abstract":"OBJECTIVE: To observe the change of Astrocyte (Ast) and cytokines, during vascular dementia (VD) formation to explore the prevention and treatment VD mechanisms of Xiongma dropping pill (XMDP). METHODS: To permanent bilateral ligation of the common carotid artery (2-VO) to establish a VD model. The glial fibrillary acidic protein（GFAP）on the rats brain, and IL-1β, IL-6 and TNF-α were observed by immunohistochemical staining and radioimmunoassay after administration 30 and 60 days. RESULTS: Compared with the sham-operation group, the number of GFAP positive cells and the contents of IL-1β, IL-6 and TNF-α were increased in the model rats (P < 0.05 or P < 0.01). Compared with the model group, XMDP and Ginkgo leaf tablets group could active or proliferative hippocampus and frontal cortex Asts, decrease the number of GFAP positive cells(P < 0.05), and decrease the contents of IL-1β, IL-6 and TNF-α(P < 0.05 or P < 0.01). In addition, the contents of IL-1β, IL-6 and TNF-α in all XMDP groups, after 60 days of administration, were remarkably greater than corresponding concentrations at 30 days(P < 0.05 or P < 0.01). CONCLUSION: XMDP could prevent and treatment VD may be associated with inhibiting the excessive activation or proliferation of Ast and to reduce the generation of the cytokines.","PeriodicalId":6396,"journal":{"name":"2010 4th International Conference on Bioinformatics and Biomedical Engineering","volume":"41 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2010-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84181892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison Study of Peptide Retention Time Prediction Model Based on Five Kinds of Amino Acid Descriptors in HPLC by Support Vector Machine 基于五种氨基酸描述符的高效液相色谱多肽保留时间预测模型的支持向量机比较研究

2010 4th International Conference on Bioinformatics and Biomedical Engineering Pub Date : 2010-06-18 DOI: 10.1109/ICBBE.2010.5516374

Jiajian Yin

{"title":"Comparison Study of Peptide Retention Time Prediction Model Based on Five Kinds of Amino Acid Descriptors in HPLC by Support Vector Machine","authors":"Jiajian Yin","doi":"10.1109/ICBBE.2010.5516374","DOIUrl":"https://doi.org/10.1109/ICBBE.2010.5516374","url":null,"abstract":"Based on amino acid descriptors(z-scales, c-scales, ISA-ECI,MS-WHIM and PRIN) and additive method, evaluation of predict performance of five amino acid descriptors in peptide QSRR(Quantitative structure-retention relationships) with 101 promiscuous peptides in High-Performance Liquid Chromato- graphy by support vector regression(SVR) is made in the article, and RBF(radical basis function) is selected as kernel function. Using leave-one-out cross-validation (LOO-CV), we suppose that predicting accuracy of ISA-ECI is better than the other descriptors in SVR with RBF. The prediction correlation coefficient of the SVR model (ε = 0.001,σ= 5 and C= 100) is 0.8445 by leave-one-out cross validation. The standard error of prediction (SEP) error of the dataset is 1.03 by fitting calculation, and the prediction correlation coefficient is 0.9642.The prediction results are in agreement with the experimental values. This paper provided a simple and effective method for predicting the retention behavior of peptide and some insight into what structural features are related to the retention time of peptides. Moreover, it also offered an idea about nonlinear relation between retention time of peptides and their structural descriptors (ISA-ECI).Therefore, SVR is assumed to be a feasible method in peptide QSAR (Quantitative structure-activity relationships) model.","PeriodicalId":6396,"journal":{"name":"2010 4th International Conference on Bioinformatics and Biomedical Engineering","volume":"87 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2010-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84192187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electroencephalograph Bicoherence for Assessing the Analgesia of Acupuncture 脑电图双相干性评价针刺镇痛作用

2010 4th International Conference on Bioinformatics and Biomedical Engineering Pub Date : 2010-06-18 DOI: 10.1109/ICBBE.2010.5516448

Ji-jun Tong, Yaming Wang, Yingying Lv, Huade Chen

{"title":"Electroencephalograph Bicoherence for Assessing the Analgesia of Acupuncture","authors":"Ji-jun Tong, Yaming Wang, Yingying Lv, Huade Chen","doi":"10.1109/ICBBE.2010.5516448","DOIUrl":"https://doi.org/10.1109/ICBBE.2010.5516448","url":null,"abstract":"n the past decades of years the systematic research on pain mechanisms has been the focus of scientists. The traditional Chinese medicine such as acupuncture has shown great potential in pain relief. Transcutaneous Electrical Acupoint Stimulation (TEAS) has been used and bicoherence of EEG has been extracted and used as evaluation criterion of pain relief in the research. In this study 12 volunteers were enrolled and each one received pain stimulation and attended two group experiments, one was transcutaneous electrical stimulation on Hegu acupoint (TEAS), the other was control group (no stimulation). The EEG was recorded and the volume of bicoherence (BIC_V) was extracted, while attended VAS test. The BIC_V increased after pain stimulation, especially in certain cerebral location (Fp1，P3，O1，O2，T6). The BIC_V decreased larger in extent in TEAS group than control group, which has the same change trend with VAS. The study primary proved the efficiency of acupuncture analgesia and BIC_V could be used as an objective assessment criterion of pain perception.","PeriodicalId":6396,"journal":{"name":"2010 4th International Conference on Bioinformatics and Biomedical Engineering","volume":"IA-21 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2010-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84605991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dissolution Characteristics of Limestone with Organic Acid 石灰石与有机酸的溶解特性

2010 4th International Conference on Bioinformatics and Biomedical Engineering Pub Date : 2010-06-18 DOI: 10.1109/ICBBE.2010.5516025

Shengyu Liu, W. Qiu, Bin Qu, Y. Xu

引用次数: 0

Study on the Effects of Ecological Engineering for Ecological Restoration on Bacterial Community Structure by Molecular Biological Method in a Eutrophic Lake 富营养化湖泊生态修复工程对细菌群落结构影响的分子生物学研究

2010 4th International Conference on Bioinformatics and Biomedical Engineering Pub Date : 2010-06-18 DOI: 10.1109/ICBBE.2010.5516097

Sheng Feng, Dinglong Li, J. Ma

{"title":"Study on the Effects of Ecological Engineering for Ecological Restoration on Bacterial Community Structure by Molecular Biological Method in a Eutrophic Lake","authors":"Sheng Feng, Dinglong Li, J. Ma","doi":"10.1109/ICBBE.2010.5516097","DOIUrl":"https://doi.org/10.1109/ICBBE.2010.5516097","url":null,"abstract":"Abstract:Study on microbial community structure and diversity in freshwater is important for exploiting the relationship of microbial community and its habitats, predicting and monitoring the ecological changing of contaminated water habitat. The retrieval of 16SrDNA genes directly from the environment has made it possible to estimate the phylogenetic diversity of a natural bacterial community without preceding cultivation steps, which reflect more comprehensively of bacterial community in the water samples in different ecological restoration areas. The genomic DNA was extracted from water, PCR amplification of this gene fragments; DGGE was analyzed; the abundance of bacteria were observed. The result showed that the bacterial community and abundance changed in different ecological restoration sections. With the depth of bio-disposal, the diversity of microbe community increased, however, the abundance of bacteria declined, which demonstrated the ecological restoration engineering improved the water habitat, promoted the microbe community diversity in the eco-restoration areas.","PeriodicalId":6396,"journal":{"name":"2010 4th International Conference on Bioinformatics and Biomedical Engineering","volume":"11 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2010-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78296910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0