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Relationship between the Self-Efficacy and Mental Health of Elderly Patients with Coronary Heart Disease in Rural Hebei Province 河北省农村老年冠心病患者自我效能感与心理健康的关系
抗癌研究 Pub Date : 2022-03-23 DOI: 10.26689/par.v6i2.3701
Ling-Ling Li, Jing Wang, Yi-Lin Wang, Jin Jiao, J. Meng, Yan Su, Xiaoming Du, Yan Wang, Guilong Sun, Yanli Li
{"title":"Relationship between the Self-Efficacy and Mental Health of Elderly Patients with Coronary Heart Disease in Rural Hebei Province","authors":"Ling-Ling Li, Jing Wang, Yi-Lin Wang, Jin Jiao, J. Meng, Yan Su, Xiaoming Du, Yan Wang, Guilong Sun, Yanli Li","doi":"10.26689/par.v6i2.3701","DOIUrl":"https://doi.org/10.26689/par.v6i2.3701","url":null,"abstract":"Objective: To investigate the self-efficacy and mental health of elderly patients with coronary heart disease (CHD) in rural Hebei Province as well as to analyze the relationship between them. Methods: From June 2021 to December 2021, 480 elderly patients with CHD from rural areas, who had been discharged by the Department of Cardiology from three tertiary hospitals in three cities with different economic levels in Hebei Province for more than a year, were selected as the research subjects. The general self-efficacy scale (GSES) and symptom self-rating scale (SCL-90) were used to investigate the self-efficacy and mental health of these patients. SPSS 25.0 was used for data analysis. Results: The total mean self-efficacy score of elderly patients with CHD in rural Hebei Province was 17.18 ± 4.68, which is lower than the international norm (t = -32.067, P = 0.000) and the national norm (t = -28.783, P = 0.000) ; the total average SCL-90 score was 148.64 ± 55.13, which is higher than the national norm for adults and the reference norm for ordinary elderly people; except for hostility and psychosis, the other dimensions were significantly higher than the national norm for adults (P < 0.05); except for psychosis, the other dimensions were significantly higher than the reference norm for ordinary elderly people (P < 0.05); the self-efficacy score was found to be negatively correlated with the total SCL-90 score and the score for each dimension (P < 0.05). Conclusion: Elderly CHD patients with higher self-efficacy in rural Hebei Province have higher mental health level. It is suggested that the mental health of elderly patients with CHD in rural areas can be improved by improving their self-efficacy.","PeriodicalId":61025,"journal":{"name":"抗癌研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48903435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Genomic Signature for the Prognosis of Survival in Relation to the Tumor Microenvironment in Esophageal Adenocarcinoma 食管腺癌生存预后的基因组特征与肿瘤微环境的关系
抗癌研究 Pub Date : 2022-03-23 DOI: 10.26689/par.v6i2.3714
Y. Qin, Minxian Tao, Lili Song, Weihua Qian, Hai-jian Gao, Lianfang Liu, Yonghua Zhang, Yingying Pan
{"title":"Genomic Signature for the Prognosis of Survival in Relation to the Tumor Microenvironment in Esophageal Adenocarcinoma","authors":"Y. Qin, Minxian Tao, Lili Song, Weihua Qian, Hai-jian Gao, Lianfang Liu, Yonghua Zhang, Yingying Pan","doi":"10.26689/par.v6i2.3714","DOIUrl":"https://doi.org/10.26689/par.v6i2.3714","url":null,"abstract":"Objective: To establish a new genomic signature for the prognosis of survival in relation to the tumor microenvironment in esophageal adenocarcinoma. Methods: Data from The Cancer Genome Atlas (TCGA) were applied, and the stromal and immune scores of patients with esophageal adenocarcinoma (EAC) were generated through the ESTIMATE algorithm. Differentially expressed genes were obtained, and genes concerning immune prognosis were identified on the basis of these scores. Functional analysis showed that these genes were primarily involved in immunobiological processes. Additionally, CIBERSORT was used to analyze 22 subgroups of tumor-infiltrating immune cells in the tumor microenvironment. Results: The results of the genomic assessment shown on the Kaplan-Meier curve revealed that EAC patients with high-risk scores have the worst survival. The risk score is valid as an independent prognostic factor for the overall survival in EAC patients. The tumor microenvironment was systematically analyzed, and the immune-related prognostic biomarkers of EAC have been proposed. Conclusion: The expression of tumor-infiltrating immune cells and immune-related genes in EAC have been identified. Some previously overlooked genes may be used as additional biomarkers for EAC in the future.","PeriodicalId":61025,"journal":{"name":"抗癌研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42560173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Effect of Laser Treatment Combined with Compound Xueshuantong Capsule in the Treatment of Diabetic Retinopathy 激光联合复方血栓通胶囊治疗糖尿病视网膜病变的临床疗效观察
抗癌研究 Pub Date : 2022-03-22 DOI: 10.26689/par.v6i2.3802
Tingwei He, Wenmin Wang, Ruiqin Li, Zongliang Song
{"title":"Clinical Effect of Laser Treatment Combined with Compound Xueshuantong Capsule in the Treatment of Diabetic Retinopathy","authors":"Tingwei He, Wenmin Wang, Ruiqin Li, Zongliang Song","doi":"10.26689/par.v6i2.3802","DOIUrl":"https://doi.org/10.26689/par.v6i2.3802","url":null,"abstract":"Objective: To determine the clinical value of compound Xueshuantong capsule in the treatment of diabetic retinopathy on the basis of laser treatment. Methods: Data were collected from 98 patients with diabetic retinopathy from February 2021 to February 2022. They were divided into two groups by drawing lots. The experimental group was treated with compound Xueshuantong capsule and laser treatment, whereas the control group was treated with laser treatment alone. Results: The absorption of exudation, resolution of retinal edema, and absorption of bleeding took longer in the control group; the incidence of visual acuity recovery to more than 0.5 and the patients’ blood glucose levels were better in the experimental group, p < 0.05. Conclusion: For patients with diabetic retinopathy, laser treatment combined with compound Xueshuantong capsule can effectively improve the visual function and rehabilitation efficiency of patients with diabetic retinopathy as well as stabilize their blood sugar levels. It has high clinical application value.","PeriodicalId":61025,"journal":{"name":"抗癌研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43553552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anti-Inflammatory and Anti-Angiogenic Properties of VitD3 in Ovarian Cancer 维生素d3在卵巢癌中的抗炎和抗血管生成特性
抗癌研究 Pub Date : 2022-03-10 DOI: 10.26689/par.v6i2.3731
N. Saghafi, A. Elham, Mahsa Khajouee
{"title":"Anti-Inflammatory and Anti-Angiogenic Properties of VitD3 in Ovarian Cancer","authors":"N. Saghafi, A. Elham, Mahsa Khajouee","doi":"10.26689/par.v6i2.3731","DOIUrl":"https://doi.org/10.26689/par.v6i2.3731","url":null,"abstract":"Ovarian malignancies are the most complicated type among all gynecological cancers. Their etiology is yet unknown; however, they are a heterogeneous, rapidly growing, and very fatal group of cancers. Chronic inflammation and angiogenesis appear to have major contributions in the development and progression of ovarian malignancies. Angiogenesis and inflammation are involved in the pathogenesis of ovarian cancer. Vitamin D3 (VitD3) has shown to have anti-inflammatory and anti-angiogenic properties in different types of cancers. The anti-inflammatory and anti-angiogenesis effects of VitD3 on ovarian cancer are investigated in this review.","PeriodicalId":61025,"journal":{"name":"抗癌研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47167292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Meta-Analysis of the Clinical Effect of Acupuncture on Postherpetic Neuralgia 针刺治疗疱疹后神经痛临床疗效的Meta分析
抗癌研究 Pub Date : 2022-01-19 DOI: 10.26689/par.v6i1.2935
Lu Wang, Zhen-Lin Chen, Shuo Zhang, Wenjing Ma, Tiantian Gao
{"title":"Meta-Analysis of the Clinical Effect of Acupuncture on Postherpetic Neuralgia","authors":"Lu Wang, Zhen-Lin Chen, Shuo Zhang, Wenjing Ma, Tiantian Gao","doi":"10.26689/par.v6i1.2935","DOIUrl":"https://doi.org/10.26689/par.v6i1.2935","url":null,"abstract":"Objective: To systematically evaluate the safety and efficacy of acupuncture on patients with postherpetic neuralgia?Methods: Based on the heyword retrieval method, China National Knowledge Infrastructure (CNKI, 1978-2020), China Biomedical Literature database (CBM, 1979-2020), VIP database (WEIPU, 1989-2020), Wanfang database (1989-2020), Cochrane Library, PubMed, and Embase were searched; randomized controlled trials of the use of acupuncture in the treatment of postherpetic neuralgia were screened out; the quality of the included literatures was evaluated based on the evaluation criteria in the Cochrane Handbook, and meta-analysis was performed using RevMan 5.3. Results: Twenty-six literatures that met the criteria, involving 2,174 patients, were included; the meta-analysis showed that compared with western medicine, the use of acupuncture can improve the overall effective rate (RR = 1.24, 95% CI [1.17, 1.32], P < 0.00001) and reduce the VAS score (MD = -1.43, 95% CI [-1.97, -0.89], P < 0.00001). Conclusion: The use of acupuncture can further improve the clinical effect of patients with postherpetic neuralgia.","PeriodicalId":61025,"journal":{"name":"抗癌研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48978078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Systematic Evaluation and Meta-Analysis of the Efficacy and Safety of Shenfu Injection in the Treatment of Septic Cardiomyopathy 参附注射液治疗脓毒症心肌病疗效和安全性的系统评价及Meta分析
抗癌研究 Pub Date : 2022-01-19 DOI: 10.26689/par.v6i1.2883
Rui Wu, Meng-ling Li
{"title":"Systematic Evaluation and Meta-Analysis of the Efficacy and Safety of Shenfu Injection in the Treatment of Septic Cardiomyopathy","authors":"Rui Wu, Meng-ling Li","doi":"10.26689/par.v6i1.2883","DOIUrl":"https://doi.org/10.26689/par.v6i1.2883","url":null,"abstract":"Objective: To evaluate the efficacy and safety of Shenfu injection in the treatment of septic cardiomyopathy. Methods: Literatures on Shenfu injection for the treatment of sepsis published from the establishment of each database to December 31, 2020, were searched by computer; Cochrane risk-of-bias tool was used for evaluating the quality of literatures, and Review Manager 5.4 software was used for meta-analysis. Results: Twenty random controlled trials (RCTs) were included, with a total of 1,179 patients; the meta-analysis showed that the routine treatment of Western medicine combined with Shenfu injection can reduce the 28-day mortality, the length of hospital stay, cardiac troponin I (cTnI), and N-terminal pro-brain natriuretic peptide (NT-proBNP) as well as improve the left ventricular ejection fraction (LVEF) with low incidence of adverse reactions. Conclusion: Western medicine combined with Shenfu injection can further reduce myocardial injury in patients with sepsis and improve cardiac function as well as the prognosis of patients with septic cardiomyopathy.","PeriodicalId":61025,"journal":{"name":"抗癌研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44896831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Observation on the Therapeutic Effect and Complication Rate of Totally Laparoscopic Total Gastrectomy and Laparoscopic-Assisted Total Gastrectomy in the Treatment of Gastric Cancer 全腹腔镜全胃切除术与腹腔镜辅助全胃切除术治疗癌症的疗效及并发症发生率观察
抗癌研究 Pub Date : 2022-01-19 DOI: 10.26689/par.v6i1.3532
Jun F Sun
{"title":"Observation on the Therapeutic Effect and Complication Rate of Totally Laparoscopic Total Gastrectomy and Laparoscopic-Assisted Total Gastrectomy in the Treatment of Gastric Cancer","authors":"Jun F Sun","doi":"10.26689/par.v6i1.3532","DOIUrl":"https://doi.org/10.26689/par.v6i1.3532","url":null,"abstract":"Objective: To investigate the effect and complication rate of totally laparoscopic and laparoscopic-assisted total gastrectomy in the treatment of gastric cancer. Methods: From March 2019 to July 2021, 60 patients with gastric cancer were selected as the subjects in this study; the patients in group A underwent laparoscopic-assisted total gastrectomy, whereas those in group B underwent totally laparoscopic total gastrectomy; the treatment effect and complication rate were compared between the two groups. Results: The postoperative recovery of group B was significantly better than that of group A, and the postoperative complications (10.00%) of group B were significantly lower than that of group A (33.33%) (P < 0.05). Conclusion: For patients with gastric cancer, totally laparoscopic total gastrectomy has better therapeutic effect and lower postoperative complications, which is worthy of popularization.","PeriodicalId":61025,"journal":{"name":"抗癌研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49313302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Research Progress on the Relationship between Vascular Aging and Hypertension 血管老化与高血压关系的研究进展
抗癌研究 Pub Date : 2021-11-30 DOI: 10.26689/par.v5i6.2796
Zeyu Si, Xiaoxuan Fan
{"title":"Research Progress on the Relationship between Vascular Aging and Hypertension","authors":"Zeyu Si, Xiaoxuan Fan","doi":"10.26689/par.v5i6.2796","DOIUrl":"https://doi.org/10.26689/par.v5i6.2796","url":null,"abstract":"Vascular aging refers to the structural and functional changes of the arterial wall with age. Vascular aging plays an important role in elderly diseases, such as hypertension. Therefore, the relationship between vascular aging and hypertension has attracted extensive attention. This article mainly reviews the mechanism of vascular aging and its influence on hypertension, so as to provide new ideas and directions for the research and prevention of hypertension.","PeriodicalId":61025,"journal":{"name":"抗癌研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47837870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Research Progress of the Maternal-Fetal Interface Immune Microenvironment Regulated by Traditional Chinese Medicine in the Treatment of Recurrent Spontaneous Abortion 中药调节母胎界面免疫微环境治疗复发性自然流产的研究进展
抗癌研究 Pub Date : 2021-11-30 DOI: 10.26689/par.v5i6.2784
Jingyi Wang, Nan Li
{"title":"Research Progress of the Maternal-Fetal Interface Immune Microenvironment Regulated by Traditional Chinese Medicine in the Treatment of Recurrent Spontaneous Abortion","authors":"Jingyi Wang, Nan Li","doi":"10.26689/par.v5i6.2784","DOIUrl":"https://doi.org/10.26689/par.v5i6.2784","url":null,"abstract":"This article is a summary of the research progress of the maternal-fetal interface immune microenvironment regulated by traditional Chinese medicine in the treatment of recurrent spontaneous abortion. The imbalance of the immune microenvironment at the maternal-fetal interface is closely related to the occurrence of recurrent spontaneous abortion. Traditional Chinese medicine can maintain the homeostasis of the immune microenvironment at the maternal-fetal interface by regulating the function of immune cells and the expression of related cytokines.","PeriodicalId":61025,"journal":{"name":"抗癌研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43625940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Research Progress on the Effect of Sphingosine Kinase 2 on Glioma 鞘氨醇激酶2对胶质瘤作用的研究进展
抗癌研究 Pub Date : 2021-11-30 DOI: 10.26689/par.v5i6.2763
Chunpeng Wang, Xiaohui Liu, Shiwen Guo
{"title":"Research Progress on the Effect of Sphingosine Kinase 2 on Glioma","authors":"Chunpeng Wang, Xiaohui Liu, Shiwen Guo","doi":"10.26689/par.v5i6.2763","DOIUrl":"https://doi.org/10.26689/par.v5i6.2763","url":null,"abstract":"Objective: The purpose of this study is to explore the role of sphingosine kinase 2 (SphK2) in the treatment of glioma, which is the most common primary tumor in the central nervous system. Methods: A total of 82 patients were included in this study, with 27 cases in the control group and 55 cases in the glioma group; the expressions of SphK2 and gp130 in the two groups were compared by immunohistochemical method, and the correlation between the two factors was analyzed. Results: Both SphK2 and gp130 were upregulated in the glioma group, and the two factors were significantly correlated. Conclusion: The high expression of SphK2 may play an important role in the occurrence, development, and diagnosis of glioma.","PeriodicalId":61025,"journal":{"name":"抗癌研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48295314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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