{"title":"维生素d3在卵巢癌中的抗炎和抗血管生成特性","authors":"N. Saghafi, A. Elham, Mahsa Khajouee","doi":"10.26689/par.v6i2.3731","DOIUrl":null,"url":null,"abstract":"Ovarian malignancies are the most complicated type among all gynecological cancers. Their etiology is yet unknown; however, they are a heterogeneous, rapidly growing, and very fatal group of cancers. Chronic inflammation and angiogenesis appear to have major contributions in the development and progression of ovarian malignancies. Angiogenesis and inflammation are involved in the pathogenesis of ovarian cancer. Vitamin D3 (VitD3) has shown to have anti-inflammatory and anti-angiogenic properties in different types of cancers. The anti-inflammatory and anti-angiogenesis effects of VitD3 on ovarian cancer are investigated in this review.","PeriodicalId":61025,"journal":{"name":"抗癌研究","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Anti-Inflammatory and Anti-Angiogenic Properties of VitD3 in Ovarian Cancer\",\"authors\":\"N. Saghafi, A. Elham, Mahsa Khajouee\",\"doi\":\"10.26689/par.v6i2.3731\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Ovarian malignancies are the most complicated type among all gynecological cancers. Their etiology is yet unknown; however, they are a heterogeneous, rapidly growing, and very fatal group of cancers. Chronic inflammation and angiogenesis appear to have major contributions in the development and progression of ovarian malignancies. Angiogenesis and inflammation are involved in the pathogenesis of ovarian cancer. Vitamin D3 (VitD3) has shown to have anti-inflammatory and anti-angiogenic properties in different types of cancers. The anti-inflammatory and anti-angiogenesis effects of VitD3 on ovarian cancer are investigated in this review.\",\"PeriodicalId\":61025,\"journal\":{\"name\":\"抗癌研究\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-03-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"抗癌研究\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.26689/par.v6i2.3731\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"抗癌研究","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.26689/par.v6i2.3731","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Anti-Inflammatory and Anti-Angiogenic Properties of VitD3 in Ovarian Cancer
Ovarian malignancies are the most complicated type among all gynecological cancers. Their etiology is yet unknown; however, they are a heterogeneous, rapidly growing, and very fatal group of cancers. Chronic inflammation and angiogenesis appear to have major contributions in the development and progression of ovarian malignancies. Angiogenesis and inflammation are involved in the pathogenesis of ovarian cancer. Vitamin D3 (VitD3) has shown to have anti-inflammatory and anti-angiogenic properties in different types of cancers. The anti-inflammatory and anti-angiogenesis effects of VitD3 on ovarian cancer are investigated in this review.
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