中国疫苗和免疫最新文献_第10页

[Study on immunogenicity of group A and group C meningococcal conjugate vaccine with coupling group B meningococcal outer membrane protein]. [偶联B组脑膜炎球菌外膜蛋白的A、C组脑膜炎球菌结合疫苗免疫原性研究]。

中国疫苗和免疫 Pub Date : 2009-10-01

Fu-Bao Ma, Hong Tao, Hong-Jun Wang

引用次数: 0

[Change of rubella antibody transferred by mother in infants]. [母婴风疹抗体的变化]。

中国疫苗和免疫 Pub Date : 2009-10-01

Rui Ma, Guo-Zhang Xu, Chao Ma

引用次数: 0

[Clinical trial on safety of inactivated split influenza virus vaccine, Anflu in 2007-2008]. [2007-2008年流感病毒分离灭活疫苗Anflu安全性的临床试验]。

中国疫苗和免疫 Pub Date : 2009-10-01

Xu Wang, Yan Liu, Yan-Wei Zhao

引用次数: 0

[Safety and immunogenicity of rabies vaccine (chick embryo cell) for human use produced in Germany and India]. [德国和印度生产的人用狂犬病疫苗(鸡胚胎细胞)的安全性和免疫原性]。

中国疫苗和免疫 Pub Date : 2009-10-01

Feng-Cai Zhu, Chuan-Hong Wu, Fan-Yue Meng

引用次数: 0

[Testing of antibodies against serogroup C Neisseria meningitidis by serum bactericidal assay in healthy population, Liaoning province]. [用血清杀菌法检测辽宁省健康人群C群脑膜炎奈瑟菌抗体]。

中国疫苗和免疫 Pub Date : 2009-10-01

Shu-Yi An, Li Xu, Yi-Xing Li

引用次数: 0

[Safety and immunogenicity of measles attenuated live vaccine prepared by master seed lot vaccine of Shanghai-191 strain]. [上海191株主苗苗制备麻疹减毒活疫苗的安全性和免疫原性]。

中国疫苗和免疫 Pub Date : 2009-10-01

Shu-Jun Zhang, Qi-You Xiao, Fang-Jun Li

{"title":"[Safety and immunogenicity of measles attenuated live vaccine prepared by master seed lot vaccine of Shanghai-191 strain].","authors":"Shu-Jun Zhang, Qi-You Xiao, Fang-Jun Li","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To evaluate the safety and immunogenicity of a new measles vaccine prepared by master seed lot original vaccine of Shanghai-191 strain.Methods: According to selection and exclusion criteria, 8-10-month healthy children, who have no history of measles, measles vaccine inoculation and vaccination contraindication were selected. The children selected were vaccinated 0.5 ml measles attenuate live vaccine prepared by master seed lot vaccine of the Shanghai-191 strain. They were observed the local and systemic response in 30 min and 6h, 24h, 48h, 72h, 7d, 14d, 21d, 28d after inoculation, and immune serum were collected before immunization and after 28 days. Measles virus antibody positive rate and geometric mean titer (GMT) were detected by hemagglutination inhibition.Results: There were not serious adverse reactions. Measles virus antibodies in serum positive rate was 100% after 28 days of immunization, and measles virus antibody GMT was 1:50.66.Conclusion: New measles vaccine prepared by master seed lot original vaccine of the Shanghai-191 strain at 8-10-month children was safe and immunogenicity.","PeriodicalId":56402,"journal":{"name":"中国疫苗和免疫","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2009-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28655897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Effect of measles control at different stages in Binzhou Municipal]. 滨州市不同阶段麻疹防控效果分析

中国疫苗和免疫 Pub Date : 2009-10-01

Guo-Qiang Cao, Ying Yang, Zhi-Guang Zhang

{"title":"[Effect of measles control at different stages in Binzhou Municipal].","authors":"Guo-Qiang Cao, Ying Yang, Zhi-Guang Zhang","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To evaluate the effect of measles control at different stages in Binzhou of Shandong.Methods: The data of measles incidence, measles vaccine (MV) coverage, the population immune levels of measles IgG antibody from 1956 to 2008, and the cost-benefit of measles control were analyzed.Results: The measles incidences were declined continually with implementing the strategies of measles control. Measles vaccine coverages have been keeping at the level of 87.12%-93.45% and the population immune levels of measles IgG antibody have been remaining at high level after implemention EPI. According to the progress of MV immunization strategy, the process of measles control could be divided into stage A (1956-1966, no specific immunization conducted), stage B (1967-1978, MV began to popularized), stage C (1979-1997, the EPI was implemented) and stage D (1998-2008, accelerated measles control and elimination). To compared between stage B and stage A, stage C and stage B, stage D and stage C, the average annual cases were decreased 9989, 18 500, and 378 respectirely, and the average annual dead cases were reduced 267, 49 and 50 respectively. The cost-benefit ratio was 1:22.97 for total 41 years on the process of the measles control and elimination from 1967 to 2008.Conclusion: The effect was obtained on the process of measles control in Binzhou city. More efforts should be made to reach the target of measles elimination.","PeriodicalId":56402,"journal":{"name":"中国疫苗和免疫","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2009-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28655898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Establishment of hepatitis B virus marker panels]. 乙型肝炎病毒标志物面板的建立

中国疫苗和免疫 Pub Date : 2009-10-01

Yong Zhang, Feng Wang, Jing-Chen Ma

引用次数: 0

[Evaluation of 5 kinds of China-made enzyme immuoassay kits for antibody to hepatitis B virus core antigen detection]. [5种国产乙型肝炎病毒核心抗原抗体酶免疫测定试剂盒评价]。

中国疫苗和免疫 Pub Date : 2009-10-01

Jing-Chen Ma, Shun-Xiang Qi, Feng Wang

{"title":"[Evaluation of 5 kinds of China-made enzyme immuoassay kits for antibody to hepatitis B virus core antigen detection].","authors":"Jing-Chen Ma, Shun-Xiang Qi, Feng Wang","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To Screen an EIA kit that fits best for using in serological detection of anti-HBc in the national investigation of hepatitis B virus infection.Methods: Top 5 kinds of kits on the best seller list of China-made anti-HBc EIA kit were selected and each detect the anti-HBc panel (95 positive and 57 negative) 5 times. The co/s ratio of each test was recorded and transformed by Ig(co/s+1). Reliability indices ICC and CV, and validity indices AUC, pAUC and Se(FPR=e) were calculated and compared between each kit.Results: The indices of ICC and CV of the 5 kinds of kits arranged in the same order of A, B, D, C and E, from the best to the worst. And the differences between them were significantly important (Bootstrap method, P < 0.05), except for between kits B and D in CV index; The AUCs ranged from 0.991 to 0.997; For index pAUCs, differences were significant between kits B, D, C ,which had the biggest values, kits A and E which had the lowest ones. For index Se(FPR=e), significant differences were only seen between kits B and A, and B and E (Bootstrap method, P < 0.05).Conclusion: The diagnostic ability of all the 5 kinds of kits arrange in an order of B, C, D, A and E, from the best to the worst.","PeriodicalId":56402,"journal":{"name":"中国疫苗和免疫","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2009-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28655893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Study on comprehensive strategies of strenghening routine immunization program]. 加强常规免疫规划的综合策略研究

中国疫苗和免疫 Pub Date : 2009-10-01

Yu-Qing Zhou, Chun-Xiang Fan, Jing-Shan Zheng

{"title":"[Study on comprehensive strategies of strenghening routine immunization program].","authors":"Yu-Qing Zhou, Chun-Xiang Fan, Jing-Shan Zheng","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To explore the feasibility and effectiveness of the comprehensive strategies to strengthen the routine immunization program, and to provide the evidence for adjusting the strategies for implementing the project in coming years.Methods: Five townships were selected from each county according to the location of east, west, south, north and middle. Four villages were selected from each township, and seven children were selected from each village randomly. There were 2215 children were investigated totally.Results: Compared with results of the baseline survey, the rate of holding immunization card increased from 89.4% to 96.3%. The coverage of 5 kinds of EPI vaccines increased between 10%-35%. The difference of coverage before and after implementing the project was significant P < 0.001. The frequency of cold chain running increased than before implementing the project. The targeted school number of immunization card school entry, the number of children checked, the number of redistributed immunization card, and the number of children catched-up vaccine increased obviously.Conclusion: The comprehensive strategies of the strengthening routine immunization program have a great effect.","PeriodicalId":56402,"journal":{"name":"中国疫苗和免疫","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2009-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28656350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0