Cranio-The Journal of Craniomandibular & Sleep Practice最新文献

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Embouchure dystonia in wind instrumentalists: Diagnostic pitfalls in dental and orofacial pain practice and a case series from an oral and maxillofacial surgery clinic. 管乐器演奏者的口部肌张力障碍:在牙科和口腔面部疼痛实践中的诊断陷阱和来自口腔颌面外科诊所的病例系列。
IF 5.4 4区 医学
Cranio-The Journal of Craniomandibular & Sleep Practice Pub Date : 2026-09-08 DOI: 10.1080/08869634.2026.2730461
Kazuya Yoshida
{"title":"Embouchure dystonia in wind instrumentalists: Diagnostic pitfalls in dental and orofacial pain practice and a case series from an oral and maxillofacial surgery clinic.","authors":"Kazuya Yoshida","doi":"10.1080/08869634.2026.2730461","DOIUrl":"https://doi.org/10.1080/08869634.2026.2730461","url":null,"abstract":"<p><strong>Objective: </strong>Embouchure dystonia is a rare task-specific orofacial movement disorder affecting wind instrumentalists and may mimic temporomandibular disorder-like or dental complaints. This study described its clinical features, diagnostic pitfalls, assessment methods, and management in an oral and maxillofacial surgery clinic.</p><p><strong>Methods: </strong>This retrospective case series included 37 patients clinically diagnosed with embouchure dystonia. Diagnosis was based on instrument-specific involuntary contraction, abnormal movement, or loss of fine motor control; task specificity; reproducibility during similar musical tasks; and exclusion of dental, temporomandibular, occlusal, bruxism-related, prosthetic, or structural findings sufficient to account for the symptoms. Temporomandibular disorders and bruxism were assessed clinically.</p><p><strong>Results: </strong>The study included 27 women and 10 men. All patients reported difficulty playing. Previous diagnoses included temporomandibular disorders, bruxism, and psychiatric disease.</p><p><strong>Conclusions: </strong>Embouchure dystonia should be considered in wind instrumentalists with instrument-specific orofacial motor symptoms unexplained by dental or temporomandibular findings.</p>","PeriodicalId":56318,"journal":{"name":"Cranio-The Journal of Craniomandibular & Sleep Practice","volume":" ","pages":"1-10"},"PeriodicalIF":5.4,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148907278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mapping therapeutic exercise interventions in temporomandibular disorders: A scoping review. 绘制治疗性运动干预颞下颌疾病:范围综述。
IF 5.4 4区 医学
Cranio-The Journal of Craniomandibular & Sleep Practice Pub Date : 2026-09-08 DOI: 10.1080/08869634.2026.2718369
Gabriele Aimini, Paolo Mastromarchi, Lorenzo Lo Russo, Marco Chiodini, Noemi Corbetta, Federico Amateis, Roberto Angelo Giovanni Bazzacchi, Stefano Salvioli
{"title":"Mapping therapeutic exercise interventions in temporomandibular disorders: A scoping review.","authors":"Gabriele Aimini, Paolo Mastromarchi, Lorenzo Lo Russo, Marco Chiodini, Noemi Corbetta, Federico Amateis, Roberto Angelo Giovanni Bazzacchi, Stefano Salvioli","doi":"10.1080/08869634.2026.2718369","DOIUrl":"https://doi.org/10.1080/08869634.2026.2718369","url":null,"abstract":"<p><strong>Objective: </strong>Temporomandibular disorders (TMDs) are musculoskeletal conditions causing pain and functional limitations. This scoping review aimed to map therapeutic exercise interventions described in clinical studies on TMDs.</p><p><strong>Methods: </strong>Following Joanna Briggs Institute methodology, searches were conducted in MEDLINE, Cochrane Central, Scopus, CINAHL, Embase, PEDro, Google Scholar, and OpenGrey.</p><p><strong>Results: </strong>Seventy-six studies were included, most prescribing oral opening movements and motor control exercises. Daily home practice was frequently prescribed, predominantly involving multiple exercise sessions per day. Guidance on whether pain should be avoided or permitted during exercise was inconsistently reported.</p><p><strong>Conclusion: </strong>Future studies should adopt standardized terminology and pain-parameter reporting, compare single versus multi-session approaches, and assess adherence to exercises to enable meta-analysis.</p>","PeriodicalId":56318,"journal":{"name":"Cranio-The Journal of Craniomandibular & Sleep Practice","volume":" ","pages":"1-13"},"PeriodicalIF":5.4,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148907280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Facial pressure pain thresholds in healthy Chinese adults: Distributions and associated factors. 中国健康成人面部压力疼痛阈值:分布及相关因素
IF 5.4 4区 医学
Cranio-The Journal of Craniomandibular & Sleep Practice Pub Date : 2026-09-06 DOI: 10.1080/08869634.2026.2725144
Houpeng Li, Fang Luo, Ming Yang, Yunhao Zheng, Hui Loon Wong, Xin Xiong
{"title":"Facial pressure pain thresholds in healthy Chinese adults: Distributions and associated factors.","authors":"Houpeng Li, Fang Luo, Ming Yang, Yunhao Zheng, Hui Loon Wong, Xin Xiong","doi":"10.1080/08869634.2026.2725144","DOIUrl":"https://doi.org/10.1080/08869634.2026.2725144","url":null,"abstract":"<p><strong>Objectives: </strong>To characterize facial pressure pain threshold (PPT) distributions and examine associations with sex, age, education, side, and anatomical region in healthy adults recruited in China.</p><p><strong>Methods: </strong>This cross-sectional study included 200 healthy adults. Bilateral PPTs were measured over the temporomandibular joint, masseter, and temporalis regions. Associations with demographic characteristics and side were examined using statistical comparisons and adjusted region-level models.</p><p><strong>Results: </strong>PPT distributions were unimodal and skewed, with a consistent regional hierarchy. Continuous age was positively associated with PPT in adjusted models; adults aged 46-60 years had higher PPT than those aged 18-30 years at all sites. Side differences were site-specific, no sex differences were detected, and education-related estimates varied by contrast.</p><p><strong>Conclusion: </strong>Facial PPT in healthy adults showed a clear regional hierarchy and varying associations with demographic characteristics. These data are more appropriate for group-level comparison than individual diagnostic use; further validation in healthy and TMD populations is needed before clinical translation.</p>","PeriodicalId":56318,"journal":{"name":"Cranio-The Journal of Craniomandibular & Sleep Practice","volume":" ","pages":"1-11"},"PeriodicalIF":5.4,"publicationDate":"2026-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148901570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cross-cultural adaptation and measurement properties analysis of the Migraine interictal burden scale-4 in Brazilian Portuguese. 巴西葡萄牙人偏头痛发作间期负担量表-4的跨文化适应及测量特性分析。
IF 5.4 4区 医学
Cranio-The Journal of Craniomandibular & Sleep Practice Pub Date : 2026-09-02 DOI: 10.1080/08869634.2026.2715381
Taciana Aline Maciel Bezerra Oliveira, Helena Cysneiros, Jaqueline Severo, Izabela Millery da Silva Cruz, Emanuel Roger Dos Santos Reis, Igor de Oliveira, Pedro Sampaio Rocha-Filho, Daniella Araújo de Oliveira
{"title":"Cross-cultural adaptation and measurement properties analysis of the Migraine interictal burden scale-4 in Brazilian Portuguese.","authors":"Taciana Aline Maciel Bezerra Oliveira, Helena Cysneiros, Jaqueline Severo, Izabela Millery da Silva Cruz, Emanuel Roger Dos Santos Reis, Igor de Oliveira, Pedro Sampaio Rocha-Filho, Daniella Araújo de Oliveira","doi":"10.1080/08869634.2026.2715381","DOIUrl":"https://doi.org/10.1080/08869634.2026.2715381","url":null,"abstract":"<p><strong>Objective: </strong>To translate, culturally adapt, and validate the measurement properties of the Migraine Interictal Burden Scale-4 (MIBS-4) for Brazilian Portuguese.</p><p><strong>Methods: </strong>This methodological study included 130 adults with migraine aged 18-55 years: 30 in translation/cross-cultural adaptation and 100 in validation. Participants completed sociodemographic, HIT-6, and MIDAS assessments. Content, construct, convergent, and criterion validity; reliability; sensitivity; and floor/ceiling effects were evaluated.  .</p><p><strong>Results: </strong>The MIBS-4 Brazil demonstrated content validity and comprehensibility (Cohen's κ=0.742, p=.004), acceptable internal consistency (α=0.714), and moderate-to-good test-retest reliability (ICC=0.737; n=52). Confirmatory factor analysis supported a unidimensional structure (CFI=1.000; RMSEA=0.000). Moderate correlations were observed with HIT-6 (r=0.496) and MIDAS (r=0.458). The MIBS-4 explained 30.2% of their combined variance (R<sup>2</sup>=0.302, p < .001). ROC analysis showed excellent accuracy for HIT-6 (AUC=0.924) and good accuracy for MIDAS (AUC=0.777). No significant floor (11%) or ceiling (2%) effects were found.      .</p><p><strong>Conclusion: </strong>The MIBS-4 Brazil is a valid and reliable instrument for assessing interictal migraine burden.</p>","PeriodicalId":56318,"journal":{"name":"Cranio-The Journal of Craniomandibular & Sleep Practice","volume":" ","pages":"1-13"},"PeriodicalIF":5.4,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148876521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations between temporomandibular disorder subtypes and oral health-related quality of life: A systematic review and meta-analysis. 颞下颌紊乱亚型与口腔健康相关生活质量之间的关系:一项系统回顾和荟萃分析
IF 5.4 4区 医学
Cranio-The Journal of Craniomandibular & Sleep Practice Pub Date : 2026-09-01 Epub Date: 2026-01-27 DOI: 10.1080/08869634.2026.2618094
Yifan Wang, Jingyi Xu, Xiaojing Li, Xin Liu, Yuhui Wan, Tian Xing
{"title":"Associations between temporomandibular disorder subtypes and oral health-related quality of life: A systematic review and meta-analysis.","authors":"Yifan Wang, Jingyi Xu, Xiaojing Li, Xin Liu, Yuhui Wan, Tian Xing","doi":"10.1080/08869634.2026.2618094","DOIUrl":"10.1080/08869634.2026.2618094","url":null,"abstract":"<p><strong>Objective: </strong>To assess associations between temporomandibular disorder (TMD) subtypes and oral health-related quality of life (OHRQoL) using meta-analysis.</p><p><strong>Methods: </strong>A systematic search of MEDLINE, PubMed, Web of Science, and the Cochrane Library identified studies up to 6 March 2024 using DC/TMD for TMD diagnosis and OHIP-based OHRQoL outcomes. Two reviewers independently screened records, extracted data, and assessed risk of bias. Standardized mean differences (SMDs) were pooled, and sensitivity analyses were performed.</p><p><strong>Results: </strong>Five studies comprising 3,267 participants were included. Compared with intra-articular TMD (IT), pain-related TMD (PT) and combined TMD (CT = PT + IT) were associated with poorer overall OHRQoL (SMD = 0.74, P < 0.001 for PT; SMD = 0.84, P < 0.001 for CT). Direct comparison showed CT had a more pronounced negative impact than PT (SMD = 0.13, P < 0.01). PT and CT also showed greater impairments in functional and psychosocial OHRQoL domains. Sensitivity analyses supported the robustness of findings.</p><p><strong>Conclusion: </strong>Patients with PT and CT symptoms exhibit significantly greater impairments in overall and domain-specific OHRQoL compared with those with IT symptoms, despite the limited number of studies included, highlighting the need for tailored treatment strategies based on TMD subtype.</p><p><strong>Registration: </strong>PROSPERO (CRD42024544762).</p>","PeriodicalId":56318,"journal":{"name":"Cranio-The Journal of Craniomandibular & Sleep Practice","volume":" ","pages":"830-843"},"PeriodicalIF":5.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146054932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of supervised machine learning models in predicting temporomandibular joint disc displacement on 3T magnetic resonance imaging. 有监督机器学习模型在3T磁共振成像上预测颞下颌关节盘位移的评估。
IF 5.4 4区 医学
Cranio-The Journal of Craniomandibular & Sleep Practice Pub Date : 2026-09-01 Epub Date: 2026-01-28 DOI: 10.1080/08869634.2026.2620624
Seyit Erol, Halil Özer, Abdi Gürhan, Mustafa Koplay, Çağlagül Erol, Nusret Seher, Mehmet Öztürk
{"title":"Evaluation of supervised machine learning models in predicting temporomandibular joint disc displacement on 3T magnetic resonance imaging.","authors":"Seyit Erol, Halil Özer, Abdi Gürhan, Mustafa Koplay, Çağlagül Erol, Nusret Seher, Mehmet Öztürk","doi":"10.1080/08869634.2026.2620624","DOIUrl":"10.1080/08869634.2026.2620624","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate supervised machine learning (ML) models for classifying temporomandibular joint (TMJ) disc displacement on MRI using morphometric and signal intensity features.</p><p><strong>Methods: </strong>This retrospective study analyzed 324 TMJs from 162 individuals who underwent 3T MRI. Extracted features included condylar anteroposterior and mediolateral diameters, disc and condyle morphology, and lateral pterygoid muscle signal intensity ratios. Six ML algorithms (Random Forest, Gaussian Naïve Bayes, Logistic Regression, AdaBoost, Gradient Boost, and k-Nearest Neighbor) were evaluated using stratified 5-fold cross-validation. Performance was assessed with accuracy, macro-averaged recall, precision, F1-score, and ROC-AUC.</p><p><strong>Results: </strong>All models demonstrated good classification performance (ROC-AUC >0.80). AdaBoost achieved the highest ROC-AUC (0.88), while Gaussian Naïve Bayes showed the most balanced overall metrics. Mediolateral condylar diameter and disc morphology were key features associated with disc displacement categories.</p><p><strong>Conclusions: </strong>ML models can identify MRI-based morphometric patterns related to TMJ disc displacement and may support radiologic assessment, while clinical diagnosis should continue to rely on established standards of care.</p>","PeriodicalId":56318,"journal":{"name":"Cranio-The Journal of Craniomandibular & Sleep Practice","volume":" ","pages":"904-916"},"PeriodicalIF":5.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146068977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship between the impact of tinnitus and craniofacial and cervical disability, dizziness, and emotional symptoms in individuals with temporomandibular disorders. 颞下颌障碍患者耳鸣与颅面和颈部残疾、头晕和情绪症状的关系
IF 5.4 4区 医学
Cranio-The Journal of Craniomandibular & Sleep Practice Pub Date : 2026-09-01 Epub Date: 2026-02-02 DOI: 10.1080/08869634.2026.2622433
Luana Denadai Oliveira Menezes, Luana Maria Ramos Mendes, Nelma Ellen Zamberlan Amorin, Lidiane Lima Florencio, Débora Bevilaqua Grossi
{"title":"Relationship between the impact of tinnitus and craniofacial and cervical disability, dizziness, and emotional symptoms in individuals with temporomandibular disorders.","authors":"Luana Denadai Oliveira Menezes, Luana Maria Ramos Mendes, Nelma Ellen Zamberlan Amorin, Lidiane Lima Florencio, Débora Bevilaqua Grossi","doi":"10.1080/08869634.2026.2622433","DOIUrl":"10.1080/08869634.2026.2622433","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the association between tinnitus impact and craniofacial and cervical disability, dizziness, anxiety, and depression in individuals with Temporomandibular Disorders (TMDs) and self-reported tinnitus.</p><p><strong>Methods: </strong>A cross-sectional study. Fifty individuals with TMDs and tinnitus completed the Tinnitus Handicap Inventory (THI), Neck Disability Index (NDI), Craniofacial Pain and Disability Inventory (CF-PDI), Dizziness Handicap Inventory (DHI), and Hospital Anxiety and Depression Scale (HADS). Prevalence, correlation. and a multiple linear regression were calculated to verify the association between THI and variables assessed.</p><p><strong>Results: </strong>Individuals with TMD and tinnitus impact have higher prevalence of cervical disability, higher prevalence of dizziness-related impact and higher prevalence of depressive symptoms than those with TMD and no tinnitus impact. THI scores presented positive and moderate correlations with NDI and HADS and 22% of its variance was explained by anxiety symptoms.</p><p><strong>Conclusion: </strong>Findings highlight the interplay between emotional and musculoskeletal factors, suggesting comprehensive and multidisciplinary management.</p>","PeriodicalId":56318,"journal":{"name":"Cranio-The Journal of Craniomandibular & Sleep Practice","volume":" ","pages":"935-943"},"PeriodicalIF":5.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146108110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Signs and symptoms of TMD and bruxism in clear aligners wearers: A cohort study. 牙齿矫正器佩戴者TMD和磨牙的症状和体征:一项队列研究。
IF 5.4 4区 医学
Cranio-The Journal of Craniomandibular & Sleep Practice Pub Date : 2026-09-01 Epub Date: 2026-02-02 DOI: 10.1080/08869634.2026.2619915
Juliana Pincetti Paiva, Mariana Dos Santos Fernandes, Fernanda Y Kobayashi, Monique Lalue-Sanches, Paula Midori Castelo
{"title":"Signs and symptoms of TMD and bruxism in clear aligners wearers: A cohort study.","authors":"Juliana Pincetti Paiva, Mariana Dos Santos Fernandes, Fernanda Y Kobayashi, Monique Lalue-Sanches, Paula Midori Castelo","doi":"10.1080/08869634.2026.2619915","DOIUrl":"10.1080/08869634.2026.2619915","url":null,"abstract":"<p><p>To evaluate signs and symptoms of temporomandibular disorders (TMD) and bruxism in aligner wearers. 87 participants were assessed through virtual questionnaire, while 20 aligner users and 20 controls were clinically followed-up for three months. Cluster analysis identified three patient profiles differing in age, pain, and oral behaviors. No association was observed between aligner use and TMD or self-reported bruxism onset. Aligner and control groups showed reduced oral habits over time, suggesting that clear aligner therapy does not increase the risk of TMD or bruxism but may contribute to greater awareness and control of oral parafunctional behaviors.</p>","PeriodicalId":56318,"journal":{"name":"Cranio-The Journal of Craniomandibular & Sleep Practice","volume":" ","pages":"871-880"},"PeriodicalIF":5.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146108425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Causal association between multiple sclerosis and trigeminal neuralgia: A Mendelian randomization study with meta-analysis. 多发性硬化症和三叉神经痛之间的因果关系:一项孟德尔随机研究和荟萃分析。
IF 5.4 4区 医学
Cranio-The Journal of Craniomandibular & Sleep Practice Pub Date : 2026-09-01 Epub Date: 2026-01-28 DOI: 10.1080/08869634.2026.2619521
Esam Halboub, Aisha A Al-Jamaei, Abdulwahab Al-Amir, Walid A Al-Soneidar, Sadeq Ali Al-Maweri, Hesham M Al-Mekhlafi, Mohammed Nasser Alhajj
{"title":"Causal association between multiple sclerosis and trigeminal neuralgia: A Mendelian randomization study with meta-analysis.","authors":"Esam Halboub, Aisha A Al-Jamaei, Abdulwahab Al-Amir, Walid A Al-Soneidar, Sadeq Ali Al-Maweri, Hesham M Al-Mekhlafi, Mohammed Nasser Alhajj","doi":"10.1080/08869634.2026.2619521","DOIUrl":"10.1080/08869634.2026.2619521","url":null,"abstract":"<p><strong>Objective: </strong>This study utilized a meta-analysis of two-sample Mendelian randomization (MR) to investigate the causal link between multiple sclerosis (MS) and trigeminal neuralgia (TN).</p><p><strong>Methods: </strong>Using genetic summary data from the OpenGWAS database (European descent), researchers identified eight MS GWAS studies as exposures and one TN study as the outcome. Ten MR approaches, including IVW and MR-Egger, were employed. Pooled estimates were calculated using a fixed-effects inverse-variance model, with significance set at P < 0.05.</p><p><strong>Results: </strong>Seven of the eight MS exposures showed a positive causal association with TN. The meta-analysis confirmed that MS significantly increases TN risk by 11% (IVW: 95% CI = 1.05-1.16; P < 0.001). Sensitivity analyses indicated no evidence of pleiotropy or heterogeneity, ensuring robust findings.</p><p><strong>Conclusion: </strong>Genetic predisposition to MS is a causal factor for TN. Further research is required to explore underlying biological pathways and validate these results across diverse populations.</p>","PeriodicalId":56318,"journal":{"name":"Cranio-The Journal of Craniomandibular & Sleep Practice","volume":" ","pages":"859-870"},"PeriodicalIF":5.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146068942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mechanobiologic modulation of TMJ loading in juvenile idiopathic arthritis. 幼年特发性关节炎中颞下颌关节负荷的机械生物学调节。
IF 5.4 4区 医学
Cranio-The Journal of Craniomandibular & Sleep Practice Pub Date : 2026-09-01 Epub Date: 2026-02-17 DOI: 10.1080/08869634.2026.2628215
Richard G Standerwick, Marinka Twilt, Edwin H K Yen, W Eugene Roberts
{"title":"Mechanobiologic modulation of TMJ loading in juvenile idiopathic arthritis.","authors":"Richard G Standerwick, Marinka Twilt, Edwin H K Yen, W Eugene Roberts","doi":"10.1080/08869634.2026.2628215","DOIUrl":"10.1080/08869634.2026.2628215","url":null,"abstract":"<p><strong>Objective: </strong>TMJ arthritis is common in juvenile idiopathic arthritis (JIA). Condylar height loss can shift mandibular loading and increase compressive TMJ stress, which may persist even when synovitis is controlled with biologics. We hypothesize that light elastics delivered via anchorage devices (TADs) can partially unload the joint.</p><p><strong>Methods: </strong>This hypothesis driven biomechanical model integrates condylar support loss, lever geometry, hyperdivergent susceptibility, and feasibility of routing low forces through a perioral soft tissue corridor. A cephalad inter implant elastic vector of ~25 to 50 g is evaluated.</p><p><strong>Results: </strong>Condylar height loss is predicted to promote backward mandibular rotation about the pterygomasseteric sling, increasing compression and vertical destabilization, especially in leptoprosopic patterns. The cephalad elastic vector is predicted to generate a counter moment, support posterior vertical neutrality, and reduce joint reaction forces.</p><p><strong>Conclusion: </strong>A low force, TAD based adjunct may complement systemic therapy by addressing loading. Imaging studies are needed to confirm.</p>","PeriodicalId":56318,"journal":{"name":"Cranio-The Journal of Craniomandibular & Sleep Practice","volume":" ","pages":"952-965"},"PeriodicalIF":5.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146215045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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