KneePub Date : 2025-02-08DOI: 10.1016/j.knee.2025.01.013
Sung-Sahn Lee, Joon-Gyom Kim, Dae-Hee Lee
{"title":"Age affects the osteotomy gap filling rate after biplanar medial opening wedge high tibial osteotomy without a bone graft.","authors":"Sung-Sahn Lee, Joon-Gyom Kim, Dae-Hee Lee","doi":"10.1016/j.knee.2025.01.013","DOIUrl":"https://doi.org/10.1016/j.knee.2025.01.013","url":null,"abstract":"<p><strong>Background: </strong>This study was designed to determine the relationship between age and osteotomy gap filling rate, aiming to discern the specific time period during which age exerts its impact on this process. The osteotomy gap filling rate after medial opening wedge high tibial osteotomy (MOWHTO) was assessed by evaluating the absolute value of gap filling utilizing computed tomography (CT) scan obtained at multiple time points postoperatively.</p><p><strong>Methods: </strong>The data of 30 patients who underwent MOWHTO between September 2019 and July 2021 were retrospectively analyzed. Computed tomography findings were used to measure osteotomy gap filling rate at 6, 12, and 24 months postoperatively. Patients were divided into two age groups (those aged ≤ 55 and > 55 years) for comparison.</p><p><strong>Results: </strong>Patients aged ≤ 55 years showed significantly greater osteotomy gap filling rate at the 6-month follow-up examination compared to that of older patients (p = 0.034). Pearson's correlation analysis revealed a negative correlation between age and osteotomy gap filling rate at 6 and 12 months postoperatively (r = -0.426, p = 0.019; r = -0.368, p = 0.046, respectively). Multiple linear regression analysis identified age as the sole predictor of osteotomy gap filling rate at 6 months postoperatively (β = -0.407, p = 0.039).</p><p><strong>Conclusion: </strong>Age significantly influenced the osteotomy gap filling rate after MOWHTO. Patients aged ≤ 55 years demonstrated greater improvement in gap filling during the initial 6-month period compared to their older counterparts. These findings underscore the importance of age considerations when deciding on the indication for MOWHTO in cases of medial knee osteoarthritis in clinical practice.</p><p><strong>Study design: </strong>Case series, Level of Evidence IV.</p>","PeriodicalId":56110,"journal":{"name":"Knee","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
KneePub Date : 2025-02-08DOI: 10.1016/j.knee.2025.01.011
Timon Röttinger, Kurt Vollert, Stefanie Tüchert, Leonard Lisitano, Khaled Salama, Heinz Röttinger, Christian Dannecker, Edgar Mayr, Johanna Abelmann-Brockmann
{"title":"The degree of patella alta in newborns shows strong correlations with patellofemoral parameters and is influenced by the intrauterine position - An ultrasound-based correlation study.","authors":"Timon Röttinger, Kurt Vollert, Stefanie Tüchert, Leonard Lisitano, Khaled Salama, Heinz Röttinger, Christian Dannecker, Edgar Mayr, Johanna Abelmann-Brockmann","doi":"10.1016/j.knee.2025.01.011","DOIUrl":"https://doi.org/10.1016/j.knee.2025.01.011","url":null,"abstract":"<p><strong>Background: </strong>Studies suggest that the development of a suitable patellar groove is highly dependent on a regular patellar position imprinting the patellofemoral joint. Furthermore, previous studies have shown that breech position also has an influence on the patellofemoral joint shape. The aim of this study is to exploratively analyze influences on patellar sagittal height in newborns.</p><p><strong>Methods: </strong>In this ultrasound-based study, parameters influencing patellar height will be exploratively examined (i.e. patellofemoral joint parameters, hip dysplasia, sex, body and age characteristics of the parents and the newborn, intrauterine position). 98 newborns born between June 2023 and November 2023 at the University Hospital receiving an ultrasound hip screening examination received additional standardized ultrasounds of their knees.</p><p><strong>Results: </strong>For all 3 measured patellar height indices patellar height was lower for newborns after breech positions. For one of the measured indices this result was significant (p = 0.018). Patellofemoral trochlear configuration also showed significant relationships to patellar height. A high sulcus angle and a lower internal rotation of the trochlea are significantly related to lower patellar heights (multiple linear regression model, model fit: p = 0.002, Coefficients: Sulcus angle p = 0.007, Trochlea angle p = 0.028).</p><p><strong>Conclusions: </strong>Breech position, high sulcus angle and lower internal rotation of the trochlea are significantly related to lower patellar heights. This is the first study to describe these relationships in newborns and increases clinical awareness. As the exact nature of the relationships remains unclear further research should be conducted.</p>","PeriodicalId":56110,"journal":{"name":"Knee","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
KneePub Date : 2025-02-08DOI: 10.1016/j.knee.2025.01.008
Keishiro Kikuchi, Joe Iwanaga, Kosuke Tabuchi, Yoko Tabira, Koichi Watanabe, Georgi P Georgiev, R Shane Tubbs
{"title":"Novel anatomical findings of the superficial medial collateral ligament during knee flexion: Anatomical and histological findings.","authors":"Keishiro Kikuchi, Joe Iwanaga, Kosuke Tabuchi, Yoko Tabira, Koichi Watanabe, Georgi P Georgiev, R Shane Tubbs","doi":"10.1016/j.knee.2025.01.008","DOIUrl":"https://doi.org/10.1016/j.knee.2025.01.008","url":null,"abstract":"<p><strong>Background: </strong>During anatomical medial collateral ligament (MCL) reconstruction, the apex of the medial femoral epicondyle (ME-apex) is a significant bony landmark. The purpose of the present study was to evaluate the anatomical relationship between the superficial MCL (sMCL) and the ME-apex using gross anatomical, and histological observations.</p><p><strong>Methods: </strong>Eight unpaired cadaveric knees were studied. The sMCL was traced from its tibial attachment, and its course at the ME-apex level was documented. The dynamic morphology of the sMCL in relation to the ME-apex was then observed throughout the range of motion, from full knee extension to 90° of knee flexion. Second, the femur, including the sMCL, was cut in the axial plane at the level of the ME-apex. Using this axial section, the anatomical relationships between the sMCL, ME-apex, and depression posterior to the ME-apex, and the morphology of the sMCL femoral attachment were examined histologically.</p><p><strong>Results: </strong>Gross anatomical observation showed that the sMCL covered the ME-apex in full knee extension. As the knee flexed, the sMCL shifted posteriorly and the ME-apex became visible. At 90° knee flexion, two separate bundles of sMCL fibers with different directions were observed. There was no direct insertion of the sMCL femoral attachment anterior to the ME-apex, only from the ME-apex to the depression posterior.</p><p><strong>Conclusion: </strong>The sMCL has the direct insertion from the ME-apex of the femur to the depression posterior to it, and shows two separate proximal fiber bundles during knee flexion. These findings offer valuable insights for improving anatomical MCL reconstruction techniques.</p>","PeriodicalId":56110,"journal":{"name":"Knee","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
KneePub Date : 2025-02-07DOI: 10.1016/j.knee.2025.01.012
Marcin Dembski , Patryk Kawa , Jakub Tarnawski , Marcin Ceynowa , Krzysztof Żerdzicki , Paweł Kłosowski
{"title":"The tensile strength of different methods of anterior cruciate ligament graft end stitches in an animal model","authors":"Marcin Dembski , Patryk Kawa , Jakub Tarnawski , Marcin Ceynowa , Krzysztof Żerdzicki , Paweł Kłosowski","doi":"10.1016/j.knee.2025.01.012","DOIUrl":"10.1016/j.knee.2025.01.012","url":null,"abstract":"<div><h3>Background</h3><div>There are several methods for stitching graft ends in anterior cruciate ligament reconstructive surgery. The tendon-suture construct should be able to withstand tensioning until the graft is stabilized with an implant.</div></div><div><h3>Methods</h3><div>In this biomechanical study, 40 porcine lower extremity tendons ends were stitched with No. 2 suture, secured to the grips of the Zwick-Roell testing machine and tested for load at failure and type of failure (tendon v/s suture thread). The applied force was linear, the results are given in Newtons (N) as a mean. The Mann-Whitney <em>U</em> test was used for statistical analysis. The following constructs were compared: a whipstitch of each tendon end individually with 3, 4, and 5 passes through the tendon, a whipstitch of both tendon ends folded together and a tendon end knot without stitching.</div></div><div><h3>Results</h3><div>All specimens survived the minimum tensile load of 80 N. The load at failure for whipstitch with 3,4 and 5 passes were 175 N, 211 N and 254 N respectively. The load at failure was greater for individual whipstitch than for both ends folded together (261 N v/s 152 N). The mean load at failure for braided graft was 209 N. The braided graft slips off the tendon before failure leading to uneven strength distribution during tensioning.</div></div><div><h3>Conclusion</h3><div>Increasing number of suture passes resulted in higher load at failure. Individual tendon ends whipstitched with 5 passes was the strongest construct. All of the investigated techniques are sufficient to withstand the suggested optimal graft tension of 80 N.</div></div>","PeriodicalId":56110,"journal":{"name":"Knee","volume":"53 ","pages":"Pages 293-301"},"PeriodicalIF":1.6,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143360570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
KneePub Date : 2025-02-07DOI: 10.1016/j.knee.2025.01.009
Camilo Partezani Helito , Andre Giardino Moreira da Silva , Filippo Familiari , Roberto Simonetta , Mateus Carlos Andrade , Daniel Esperante Gomes , Christoffer von Essen , Riccardo Cristiani
{"title":"Clinical outcomes of repaired radial meniscal tears: A retrospective study with minimum 2-year follow-up","authors":"Camilo Partezani Helito , Andre Giardino Moreira da Silva , Filippo Familiari , Roberto Simonetta , Mateus Carlos Andrade , Daniel Esperante Gomes , Christoffer von Essen , Riccardo Cristiani","doi":"10.1016/j.knee.2025.01.009","DOIUrl":"10.1016/j.knee.2025.01.009","url":null,"abstract":"<div><h3>Background</h3><div>The management of meniscal radial tears has changed significantly in recent years in favor of meniscus repair. However, there is still limited published data on the outcomes and risk factors associated with repair failure. The objective of this study is to evaluate the clinical success rate of repaired meniscal radial tears and identify potential risk factors for failure.</div></div><div><h3>Methods</h3><div>Patients who underwent repair of meniscal radial tears between 2016 and 2022 were reviewed retrospectively. The following parameters were collected: demographic data, pre-operative Kellgren-Lawrence grading, history of previous knee surgeries, time from injury to surgery, injury location, number of sutures used, use of transtibial tunnel augmentation, associated procedures, postoperative functional scores, and clinical failure rates.</div></div><div><h3>Results</h3><div>81 patients were included, with a mean age of 29.9 ± 12.3 years. The mean follow-up time was 36.7 ± 17.0 months. Postoperatively, the mean IKDC was 81 ± 18.1, and the mean Lysholm score was 82 ± 18.4. The clinical failure rate was 19.8%. In the univariate analysis, the factors associated with failure included increased age, female gender, medial meniscus repair, isolated repairs (without ACL reconstruction), a Kellgren-Lawrence scale greater than 0, and repairs without a transtibial tunnel. However, none of these variables were statistically significant in the multivariate analysis adjusted for age and gender.</div></div><div><h3>Conclusion</h3><div>The clinical success rate of repaired meniscal radial tears was about 80% after a minimum 2-year follow-up. Increased age, female gender, repair of medial meniscus, isolated repair without ACL reconstruction, mild preoperative osteoarthritic signs, and repair without a transtibial tunnel augmentation are possible risk factors for failure.</div></div><div><h3>Level of evidence</h3><div>Level IV, retrospective case series.</div></div>","PeriodicalId":56110,"journal":{"name":"Knee","volume":"53 ","pages":"Pages 285-292"},"PeriodicalIF":1.6,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143348393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
KneePub Date : 2025-02-07DOI: 10.1016/j.knee.2025.01.014
Shaozheng Yang , Guangyuan Dong , Jianying Pan , Yongqiang Liu , Hua Zhong , Chun Zeng
{"title":"Similarities in the kinematics of autografts and hybrid grafts for anterior cruciate ligament reconstruction: Minimum 2 years of follow-up","authors":"Shaozheng Yang , Guangyuan Dong , Jianying Pan , Yongqiang Liu , Hua Zhong , Chun Zeng","doi":"10.1016/j.knee.2025.01.014","DOIUrl":"10.1016/j.knee.2025.01.014","url":null,"abstract":"<div><h3>Objective</h3><div>To compare the clinical results of anterior cruciate ligament reconstruction (ACLR) with autografts and that with hybrid grafts of the same diameter.</div></div><div><h3>Methods</h3><div>This study retrospectively included 102 patients who underwent ACLR from August 2017 to July 2019. According to graft type, the patients were divided into an autograft group (58 patients) and a hybrid graft group (44 patients). All grafts were 8.0 mm in diameter. The failure rate, knee kinematics with 6 degrees of freedom (DOFs), signal/noise quotient (SNQ), the Lachman test, pivot-shift test, Lysholm score, Tegner activity score, and International Knee Documentation Committee (IKDC) score were compared in each group after a minimum 2-year follow-up.</div></div><div><h3>Results</h3><div>There was no significant difference in the failure rate between the autograft group (1.72%) and the hybrid graft group (2.27%) (<em>P</em> > 0.999). The SNQ values of the autograft group (16.42 ± 5.29 and 18.52 ± 5.30) at the middle and proximal sites were lower than those of the hybrid graft group (12.13 ± 5.62 and 16.35 ± 4.64; <em>P</em> = 0.020 and <em>P</em> < 0.001, respectively). In the autograft group, the results of range of motion at 6 DOFs and tibiofemoral kinematics at 5 DOFs (except internal-external rotation) were similar to those of the hybrid graft group (<em>P</em> > 0.05). The Lysholm score, Tegner activity score, IKDC score, Lachman test, and pivot-shift test showed no differences between the two groups (<em>P</em> > 0.05).</div></div><div><h3>Conclusions</h3><div>Autograft in ACLR has better graft maturity than hybrid grafts, but their kinematic characteristics are similar.</div></div><div><h3>Clinical trial registration</h3><div>ChiCTR2000037869.</div></div>","PeriodicalId":56110,"journal":{"name":"Knee","volume":"53 ","pages":"Pages 273-284"},"PeriodicalIF":1.6,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143348391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
KneePub Date : 2025-02-07DOI: 10.1016/j.knee.2025.01.010
Cass Nakasone , Ian Weber , Craig Israelite , Jason Cholewa
{"title":"Early radiographic evaluation of an anatomic porous tantalum tibia: A prospective, multi-center, non-randomized clinical study","authors":"Cass Nakasone , Ian Weber , Craig Israelite , Jason Cholewa","doi":"10.1016/j.knee.2025.01.010","DOIUrl":"10.1016/j.knee.2025.01.010","url":null,"abstract":"<div><h3>Background</h3><div>Excellent survival rates have been reported for total knee arthroplasty (TKA) performed with cementless porous metal tibial components. More data, however, is necessary to assess the survival and radiographic results of modular implants with anatomic designs. The purpose of this study was to investigate the early radiographic, survival, and clinical outcomes of a cementless tantalum metal tibial implant with a modular anatomic component.</div></div><div><h3>Methods</h3><div>An early follow-up of a prospective, multi-center, non-randomized outcomes study of patients who received cementless tibial implants in primary TKA between 2018 and 2020 was performed. A total of 148 implants were available for review. Radiographs, the Forgotten Joint Score (FJS-12), Oxford Knee Score (OKS), patient satisfaction, and adverse events were collected for at least two-years post-operative. A minimum of two-years follow-up was available for 119 patients and evaluated for progressive radiolucent lines (RLLs).</div></div><div><h3>Results</h3><div>The mean follow-up was 2.2 ± 0.6 years, and the two-year implant survival rate was 98.59% (95% C.I.: 94.46, 99.64) with no aseptic revisions during the follow-up period. Progressive tibial RLLs were present in 3.4% of patients at two-years follow-up, but were all less than 2 mm with all combined RLLs less than 4 mm. The FJS-12 and OKS all significantly (p < 0.0001) increased and exceeded their respective minimal clinical important differences, and 93% of patients were satisfied at two-years follow-up.</div></div><div><h3>Conclusion</h3><div>This study supports excellent survivorship, clinical and patient reported outcomes using cementless, fixed bearing TKA with minimal complications at early follow-up. Further follow-up is necessary to confirm the sustainability of the clinical outcomes and to evaluate mid- to long-term survivorship.</div></div>","PeriodicalId":56110,"journal":{"name":"Knee","volume":"53 ","pages":"Pages 264-272"},"PeriodicalIF":1.6,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143360571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
KneePub Date : 2025-02-04DOI: 10.1016/j.knee.2025.01.005
Chilan Bou Ghosson Leite , Alexander Bumberger , Domenico Franco , Marco Tulio Di Stefano , Christian Lattermann
{"title":"Effect of specialized pro-resolving mediators on knee joint inflammation","authors":"Chilan Bou Ghosson Leite , Alexander Bumberger , Domenico Franco , Marco Tulio Di Stefano , Christian Lattermann","doi":"10.1016/j.knee.2025.01.005","DOIUrl":"10.1016/j.knee.2025.01.005","url":null,"abstract":"<div><h3>Background</h3><div>Chronic inflammation following knee injuries often results in persistent knee pain and post-traumatic osteoarthritis (PTOA). Understanding the inflammatory processes that follow a joint injury is crucial to effectively mitigate PTOA progression. While inflammation is an integral part of any healing response, unresolved, long-lasting inflammation can be detrimental to the joint. The resolution of inflammation is an active process coordinated by pro-resolving molecules, including specialized pro-resolving mediators (SPMs). While SPMs have been primarily studied in chronic inflammatory diseases, their role in degenerative knee conditions such as PTOA remains underexplored.</div></div><div><h3>Methods</h3><div>This review examines the process of inflammation and its resolution following knee joint injuries and subsequent PTOA, with a focus on the impact of SPMs.</div></div><div><h3>Conclusions</h3><div>SPMs play a key role in the resolution of inflammation and may offer potential benefits in the management of knee injuries to improve pain and prevent PTOA.</div></div>","PeriodicalId":56110,"journal":{"name":"Knee","volume":"53 ","pages":"Pages 257-263"},"PeriodicalIF":1.6,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143181807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
KneePub Date : 2025-01-30DOI: 10.1016/j.knee.2025.01.004
Pedro Felipe Austregésilo de Alencar , Guilherme Sávio Lima Frota , Guilherme Nobre Nogueira , Larissa Amorim Teixeira
{"title":"Letter to the Editors: Quadriceps tendon versus hamstring tendon graft for primary anterior cruciate ligament reconstruction: Is there any difference? Knee 2024;49:226–40","authors":"Pedro Felipe Austregésilo de Alencar , Guilherme Sávio Lima Frota , Guilherme Nobre Nogueira , Larissa Amorim Teixeira","doi":"10.1016/j.knee.2025.01.004","DOIUrl":"10.1016/j.knee.2025.01.004","url":null,"abstract":"","PeriodicalId":56110,"journal":{"name":"Knee","volume":"53 ","pages":"Pages 255-256"},"PeriodicalIF":1.6,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143076394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
KneePub Date : 2025-01-25DOI: 10.1016/j.knee.2024.12.009
Bernard de Geofroy , Tristan Fauchille , Michael Djian , Marc-Olivier Gauci , Jean-Yves Bohic , Xavier Pocquet , Grégoire Micicoi
{"title":"Individualized total knee arthroplasty achieves better functional results than off-the-shelf implants in patients undergoing personalized coronal alignment","authors":"Bernard de Geofroy , Tristan Fauchille , Michael Djian , Marc-Olivier Gauci , Jean-Yves Bohic , Xavier Pocquet , Grégoire Micicoi","doi":"10.1016/j.knee.2024.12.009","DOIUrl":"10.1016/j.knee.2024.12.009","url":null,"abstract":"<div><h3>Background</h3><div>Several studies have demonstrated the interest in patient-specific custom cutting guides in total knee arthroplasty (TKA), but clinical improvement remains debated. The purpose of this study was to evaluate the functional outcomes (Forgotten Joint Score, FJS) of patients undergoing individualized TKA compared with those receiving off-the-shelf (OTS) implants, both using patient-specific cutting guides with personalized alignment over a minimum follow up period of 12 months. We hypothesized that individualized TKA demonstrates significantly better functional outcomes than OTS TKA (FJS and percentage of patients reaching the minimum clinically important difference).</div></div><div><h3>Methods</h3><div>A continuous single-surgeon retrospective series was analyzed from September 2018 to June 2020. The inclusion criterion was primary TKA for osteoarthritis. The series compared 58 individualized TKAs to 54 standard implants, with personalized alignment, at a mean follow up of 25 (12–40) months. The two groups were comparable in gender, age, BMI, and preoperative deformity. Complications and revision procedures were recorded. The FJS, New IKS, and Oxford Knee Score were assessed at the last follow up, and the sensation of a forgotten knee was evaluated.</div></div><div><h3>Results</h3><div>One patient in each group required TKA revision. At last follow up, the individualized TKA group showed significantly better FJS (91 ± 14 vs. 81 ± 23, <em>P</em> = 0.01), satisfaction category in the IKS (36 ± 5 vs. 32 ± 8, <em>P</em> = 0.002), IKS function (83 ± 11 vs. 72 ± 21, <em>P</em> = 0.003) and Oxford scores (44 ± 5 vs. 39 ± 10, <em>P</em> = 0.005. There was no significant difference in the IKS objective score (88 ± 16 vs. 82 ± 2, <em>P</em> = 0.34). The sensation of a forgotten knee rate did not differ significantly between the groups.</div></div><div><h3>Conclusion</h3><div>Individualized TKA leads to improved clinical outcomes significantly compared with OTS TKA, utilizing personalized alignment and patient-specific cutting guides. This combination of personalized factors and individualized TKA enhances the potential to tackle the challenges associated with TKA and improve functional results.</div></div>","PeriodicalId":56110,"journal":{"name":"Knee","volume":"53 ","pages":"Pages 228-235"},"PeriodicalIF":1.6,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}