Oral RadiologyPub Date : 2023-12-15DOI: 10.1007/s11282-023-00723-5
Philippe Biel, Alice Jurt, Vivianne Chappuis, Valerie G. A. Suter
{"title":"Incidental findings in cone beam computed tomography (CBCT) scans for implant treatment planning: a retrospective study of 404 CBCT scans","authors":"Philippe Biel, Alice Jurt, Vivianne Chappuis, Valerie G. A. Suter","doi":"10.1007/s11282-023-00723-5","DOIUrl":"https://doi.org/10.1007/s11282-023-00723-5","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Objectives</h3><p>To investigate the prevalence of incidental findings and need for further dental treatment and analyse the influence of size of field-of-view (FOV) and age in cone beam computed tomography (CBCT) for pre-implant planning.</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>404 CBCT scans were examined retrospectively for incidental findings and need for further dental treatment. Incidental finding-frequencies and need for further treatment were assessed for different age (< 40 years, 40–60 years, > 60 years) and FOV groups (small, medium, large). Intraexaminer and interexaminer agreements were evaluated.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>In 82% of the scans at least one incidental finding was found, with a total of 766 overall. More incidental findings were found in scans with large FOV (98% vs. 72%, OR = 22.39 large vs. small FOV, <i>p</i> < 0.0001) and in scans of patients > 60 years (OR = 5.37 patient’s age > 60 years vs. < 40 years, <i>p</i> = 0.0003). Further dental treatment due to incidental findings was needed in 31%. Scans with large FOV were more likely to entail further treatment (OR = 3.55 large vs. small FOV, <i>p</i> < 0.0001). Partial edentulism and large FOV were identified as risk factors for further treatment (<i>p</i> = 0.0003 and <i>p</i> < 0.0001). Further referral of the patient based on incidental findings was judged as indicated in 5%. Intra- and inter-examiner agreements were excellent (kappa = 0.944/0.805).</p><h3 data-test=\"abstract-sub-heading\">Conclusions</h3><p>A considerable number of incidental findings with need for further dental treatment was found in partially edentulous patients and in patients > 60 years. In pre-implant planning of elderly patients, the selection of large FOV CBCT scans, including dentoalveolar regions not X-rayed recently, help to detect therapeutically relevant incidental findings.</p>","PeriodicalId":56103,"journal":{"name":"Oral Radiology","volume":"10 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138693227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral RadiologyPub Date : 2023-12-08DOI: 10.1007/s11282-023-00722-6
Ahmet Turan Kaya, Levent Uğur
{"title":"Relationship between maxillary sinus mucosal cyst and sinus ostium 2D area in three-dimensional volumetric paranasal CT ımages","authors":"Ahmet Turan Kaya, Levent Uğur","doi":"10.1007/s11282-023-00722-6","DOIUrl":"https://doi.org/10.1007/s11282-023-00722-6","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Objective</h3><p>To investigate the relationship between the maxillary sinus ostium 2D area (SOA) and the development of mucosal cysts of the maxillary sinus (MMC).</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>Thirty patients (≥ 18 years) with unilateral MMC who underwent paranasal sinus CT (PNsCT) were included in this single-center retrospective study. Non-MMC sinus was used as the control group. Cyst and air volume of the maxillary sinuses, diameter, and 2-dimensional area of the ostium of the patients were calculated in the 3-dimensional volumetric analysis program. Both correlation and linear regression model analyses were performed for the relationship between MMC and SOA.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>Thirty patients were included (mean age of 42.30 ± 17.62 years). A total of 15/30 (50%) were male. The mean SOA in patients with MMC (8.91 ± 1.10 mm<sup>2</sup>) was lower than in patients without MMC (12.94 ± 1.35 mm<sup>2</sup>), which was statistically significant (<i>p</i> < 0.001). The mean sinus ostium diameter in patients with MMC (2.12 ± 0.71 mm) was higher than in patients without MMC (1.91 ± 0.82 mm), which was statistically insignificant (<i>p</i> = 0.295). There was a statistically significant, good level of negative linear correlation between SOA and total cyst volume (TCV) [correlation coefficient (<i>r</i>) = – 0.680, <i>p</i> < 0.001]). As a result, the regression model consisting of \"Age, Sinus air volume, and TCV\" variables is a good model and has statistically significant relations with SOA.</p><h3 data-test=\"abstract-sub-heading\">Conclusion</h3><p>In conclusion, small SOAs contribute to the development of MMC. There was a negative correlation between SOA and TCV. In addition, 2D area measurement may be a more accurate method instead of diameter measurement.</p>","PeriodicalId":56103,"journal":{"name":"Oral Radiology","volume":"58 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138556046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral RadiologyPub Date : 2023-10-01Epub Date: 2023-06-27DOI: 10.1007/s11282-023-00693-8
Beatriz Fernandes Arrepia, Thaiza Gonçalves Rocha, Annie Seabra Medeiros, Matheus Diniz Ferreira, Andrea Fonseca-Gonçalves, Maria Augusta Visconti
{"title":"The mandibular bone structure in children by fractal dimension and its correlation with pixel intensity values: a pilot study.","authors":"Beatriz Fernandes Arrepia, Thaiza Gonçalves Rocha, Annie Seabra Medeiros, Matheus Diniz Ferreira, Andrea Fonseca-Gonçalves, Maria Augusta Visconti","doi":"10.1007/s11282-023-00693-8","DOIUrl":"10.1007/s11282-023-00693-8","url":null,"abstract":"<p><strong>Objectives: </strong>To identify a normal pattern of mandibular trabecular bone in children based on the fractal dimension (FD), and its possible correlation with pixel intensity (PI) values, to facilitate the early diagnosis of possible diseases and/or future bone alterations.</p><p><strong>Materials and methods: </strong>The 50 panoramic images were selected and divided into two groups, according to the children's age: 8-9 (Group 1; n = 25) and 6-7 (Group 2; n = 25). For FD and PI analyses, three regions of interest (ROIs) were selected, and their mean values were evaluated for each ROI, according to each group, using the t test for independent samples and the model of generalized estimation equations (GEE). Subsequently, these mean values were correlated by the Pearson test.</p><p><strong>Results: </strong>Comparing the groups, FD and PI did not differ from each other for any of the measured regions (p > 0.00). It was observed that in the mandible branch (ROI1), FD and PI means were 1.26 ± 0.01 and 81.0 ± 2.50, respectively. In the mandible angle (ROI2), the means were 1.21 ± 0.02 (FD) and 72.8 ± 2.13 (PI); and in the mandible, cortical (ROI3) values of FD = 1.03 ± 0.01 and PI = 91.3 ± 1.75 were obtained. There was no correlation between FD and PI in any of the analyzed ROI (r < 0.285). The FD means of ROI1 and ROI2 did not differ from each other (p = 0.053), but both were different from ROI3 (p < 0.00). All PI values differed from each other (p < 0.00).</p><p><strong>Conclusion: </strong>The bone trabeculate pattern in 6-9-year-old children presented FD between 1.01 and 1.29. Besides that, there was no significant correlation between FD and PI.</p>","PeriodicalId":56103,"journal":{"name":"Oral Radiology","volume":"39 4","pages":"771-778"},"PeriodicalIF":2.2,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10645439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral RadiologyPub Date : 2023-10-01Epub Date: 2023-06-15DOI: 10.1007/s11282-023-00697-4
Lays Assolini Pinheiro de Oliveira, João Pedro Perez Gomes, Luciana Ramalho Pimentel-Silva, Sérgio Lúcio Pereira de Castro Lopes, Maria Elvira Pizzigatti Correa, Adriana de Oliveira Lira, Andre Luiz Ferreira Costa
{"title":"Magnetic resonance imaging evaluation of the disc morphology of temporomandibular joint in patients with severe hemophilia.","authors":"Lays Assolini Pinheiro de Oliveira, João Pedro Perez Gomes, Luciana Ramalho Pimentel-Silva, Sérgio Lúcio Pereira de Castro Lopes, Maria Elvira Pizzigatti Correa, Adriana de Oliveira Lira, Andre Luiz Ferreira Costa","doi":"10.1007/s11282-023-00697-4","DOIUrl":"10.1007/s11282-023-00697-4","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to assess the morphological differences in the articular disc (AD) between hemophilic patients and healthy individuals of the control group for further association with signs and symptoms.</p><p><strong>Methods: </strong>Fourteen severe hemophilic patients had their AD evaluated by magnetic resonance imaging (MRI). The morphological findings were compared to those of a control group consisting of 14 healthy individuals. MRI was used to evaluate all the components of the temporomandibular (TMJ), including the AD, resulting in sequential T1-weighted parasagittal images. All the images were acquired with teeth in maximum intercuspation position.</p><p><strong>Results: </strong>Morphological alterations showed significant statistical differences (P-value = 0.0068), whereas no statistical differences were found in the other variables, including TMJ pain, headache, bruxism and mouth opening limitation. In the group of non-hemophilic individuals, only two (14.29%) presented AD with non-biconcave features, whereas in the group of hemophilic patients, nine (64.29%) presented AD with a morphology other than biconcave.</p><p><strong>Conclusions: </strong>In patients with severe hemophilia, there seems to be a pattern of morphological alterations in the articular disc over time. The standard biconcave morphology of AD tends to change into other ones, particularly biplanar, hemiconvex and folded.</p>","PeriodicalId":56103,"journal":{"name":"Oral Radiology","volume":"39 4","pages":"759-765"},"PeriodicalIF":2.2,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10282122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral RadiologyPub Date : 2023-10-01Epub Date: 2023-07-25DOI: 10.1007/s11282-023-00701-x
Chieko Sugawara, Akira Takahashi
{"title":"Orofacial symptoms suggestive of malignant lesions and the role of imaging: literature review and case presentation.","authors":"Chieko Sugawara, Akira Takahashi","doi":"10.1007/s11282-023-00701-x","DOIUrl":"10.1007/s11282-023-00701-x","url":null,"abstract":"<p><p>Among the patients seeking dental treatment, some may present with symptoms that cannot be resolved by dental treatment alone. Patients with orofacial symptoms associated with malignant diseases, which require medical treatment, often visit dental clinics for their initial consultation. Delays in making a definitive diagnosis worsen the patient's prognosis. Therefore, dental clinicians should also be aware of the signs and symptoms associated with malignant diseases. The chief complaints of these patients include numb chin syndrome (NCS), painless swelling of the palate and neck, trismus and temporomandibular disorders, and an enlarged tongue. This article aimed to review these orofacial symptoms and related diseases and describe representative cases of these diseases to obtain a definitive diagnosis via imaging. Panoramic radiograph is widely used in general dentistry, and this article reaffirmed the importance of panoramic radiograph anatomical landmarks in diagnosing the cases presented in this paper.</p>","PeriodicalId":56103,"journal":{"name":"Oral Radiology","volume":"39 4","pages":"599-613"},"PeriodicalIF":2.2,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10283566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Non-Gaussian model-based diffusion-weighted imaging of oral squamous cell carcinoma: associations with Ki-67 proliferation status.","authors":"Tomoka Shima, Noriyuki Fujima, Shigeru Yamano, Hiroyuki Kameda, Masaaki Suzuka, Akiko Takeuchi, Yurika Kinoshita, Nanami Iwai, Kohsuke Kudo, Kazuyuki Minowa","doi":"10.1007/s11282-023-00682-x","DOIUrl":"10.1007/s11282-023-00682-x","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate possible associations between diffusion-weighted imaging (DWI) parameters derived from a non-Gaussian model fitting and Ki-67 status in patients with oral squamous cell carcinoma (OSCC).</p><p><strong>Methods: </strong>Twenty-four patients with newly diagnosed OSCC were prospectively recruited. DWI was performed using six b-values (0-2500). The diffusion-related parameters of kurtosis value (K), kurtosis-corrected diffusion coefficient (D<sub>K</sub>), diffusion heterogeneity (α), distributed diffusion coefficient (DDC), slow diffusion coefficient (D<sub>slow</sub>), and apparent diffusion coefficient (ADC) were calculated from four diffusion fitting models. Ki-67 status was categorized as low (Ki-67 percentage score < 20%), middle (20-50%), or high (> 50%). Kruskal-Wallis tests were performed between each non-Gaussian diffusion model parameters and Ki-67 grade.</p><p><strong>Results: </strong>The Kruskal-Wallis tests revealed that multiple parameters (K, ADC, D<sub>k</sub>, DDC and D<sub>slow</sub>) showed statistically significant differences between the three levels of Ki-67 status (K: p = 0.020, ADC: p = 0.012, D<sub>k</sub>: p = 0.027, DDC: p = 0.007 and D<sub>slow</sub>: p = 0.026).</p><p><strong>Conclusions: </strong>Several non-Gaussian diffusion model parameters and ADC values were significantly associated with Ki-67 status and have potential as promising prognostic biomarkers in patients with OSCC.</p>","PeriodicalId":56103,"journal":{"name":"Oral Radiology","volume":"39 4","pages":"661-667"},"PeriodicalIF":2.2,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10331055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Volume-based 18F-fluorodeoxyglucose positron emission tomography/computed tomography parameters correlate with delayed neck metastasis in clinical early-stage oral squamous cell carcinoma.","authors":"Nobuhiro Yamakawa, Yohei Nakayama, Nobuhiro Ueda, Takahiro Yagyuu, Shigehiro Tamaki, Tadaaki Kirita","doi":"10.1007/s11282-023-00686-7","DOIUrl":"10.1007/s11282-023-00686-7","url":null,"abstract":"<p><strong>Objective: </strong>There is no known preoperative marker that can effectively predict the risk of delayed neck metastasis (DNM), which is an important factor that determines the prognosis of early-stage oral cancer. In this study, we examined whether 18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET)/computed tomography (CT) uptake parameters of primary cancer can predict the risk of DNM in early-stage oral squamous cell carcinoma (OSCC).</p><p><strong>Methods: </strong>Data from patients with stage I-II OSCC who underwent surgical resection of the primary tumor without elective neck dissection between January 2009 and December 2016 were retrospectively reviewed. Patient characteristics, histopathological factors, and PET/CT parameters (maximum standardized uptake value [SUVmax], metabolic tumor volume [MTV], and total lesion glycolysis [TLG]) were evaluated for their association with DNM. DNM rates were calculated, and the parameters that were statistically significant in the univariate analysis were used as explanatory variables. Independent factors associated with DNM were identified using multivariate analysis. For all statistical analyses, p-values < 0.05 were considered statistically significant.</p><p><strong>Results: </strong>Data from 71 patients were analyzed in the study. The overall DNM rate among all patients was 21.8%. The univariate analysis showed that the T classification, depth of invasion, pattern of invasion, lymphovascular invasion, SUVmax, MTV, and TLG were significant predictors of DNM. However, the multivariate analysis revealed that only the depth of invasion, MTV, and TLG were independent predictors of DNM.</p><p><strong>Conclusion: </strong>This study suggests that, in addition to conventional predictors, volume-based PET parameters are useful predictors of DNM in those with early-stage OSCC.</p>","PeriodicalId":56103,"journal":{"name":"Oral Radiology","volume":"39 4","pages":"668-682"},"PeriodicalIF":2.2,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10331087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral RadiologyPub Date : 2023-10-01Epub Date: 2023-05-22DOI: 10.1007/s11282-023-00688-5
Zeynep Betül Arslan, Füsun Yaşar
{"title":"Evaluation of the thickness and internal structure of the masseter muscle with ultrasonography in female bruxism patients.","authors":"Zeynep Betül Arslan, Füsun Yaşar","doi":"10.1007/s11282-023-00688-5","DOIUrl":"10.1007/s11282-023-00688-5","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this study was to evaluate the differences in the thickness and internal structure of the masseter muscle in individuals with and without bruxism by ultrasonography.</p><p><strong>Materials and methods: </strong>A total of 60 female patients with and without bruxism whose ages were ranging between 20 and 35 were included in the study. The masseter muscle thickness was measured during rest and maximum bite position. Ultrasonographic internal structure of the masseter muscle is classified according to the visibility of echogenic bands. In addition, the echogenic internal structure of the masseter muscle was evaluated with quantitative muscle ultrasound.</p><p><strong>Results: </strong>The masseter muscle thickness was significantly higher in both positions in patients with bruxism (p < 0.05). There was no significant difference between two groups in the evaluation of echogenicity (p > 0.05).</p><p><strong>Conclusions: </strong>Ultrasonography is a useful and important diagnostic method for evaluating masseter muscle without using radiation.</p>","PeriodicalId":56103,"journal":{"name":"Oral Radiology","volume":"39 4","pages":"708-714"},"PeriodicalIF":2.2,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10278468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral RadiologyPub Date : 2023-10-01Epub Date: 2023-03-15DOI: 10.1007/s11282-023-00679-6
Ceyda Gündoğdu, Sinem Akgül
{"title":"Radiopacity evaluation of different types of resin restorative materials using a digital radiography system.","authors":"Ceyda Gündoğdu, Sinem Akgül","doi":"10.1007/s11282-023-00679-6","DOIUrl":"10.1007/s11282-023-00679-6","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of the study was to evaluate and compare the radiopacity of 20 current dental resin composites with digital radiography.</p><p><strong>Methods: </strong>Ten specimens, 10-mm in diameter and 1-mm thickness, were prepared and radiographed using phosphor plates close to Al step wedges and tooth sections. The mean grey values (MGVs) were measured using an ImageJ software program and converted to equivalent Al thickness. Data were analyzed using one-way analysis of variance (ANOVA) and Tamhane post hoc test (p < 0.05). Correlation between mean radiopacity and filler content (wt% and vol%) of the tested materials was analyzed with linear regression analysis.</p><p><strong>Results: </strong>The radiopacity of all composites ranged from 1.32 mm Al (Estellite Flow Quick) to 3.41 mm Al (Charisma Classic). All the tested materials, except four restorative materials, had a radiopacity equal or higher than the enamel (p < 0.05). Linear regression revealed low correlation between the radiopacity and filler content of the composite.</p><p><strong>Conclusion: </strong>Majority of the materials has appropriate radiopacity for dental restorations. There was great variation in radiopacity level, may clinically affect the diagnosis.</p>","PeriodicalId":56103,"journal":{"name":"Oral Radiology","volume":"39 4","pages":"646-653"},"PeriodicalIF":2.2,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10281132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral RadiologyPub Date : 2023-10-01Epub Date: 2023-07-20DOI: 10.1007/s11282-023-00700-y
Kyriaki Seremidi, Anastasia Mitsea, William Papaioannou, Konstantina Petroleka, Sotiria Gizani
{"title":"Assessing quality and quantity of cortical bone in childhood cancer survivors using anthropometric indices.","authors":"Kyriaki Seremidi, Anastasia Mitsea, William Papaioannou, Konstantina Petroleka, Sotiria Gizani","doi":"10.1007/s11282-023-00700-y","DOIUrl":"10.1007/s11282-023-00700-y","url":null,"abstract":"<p><strong>Objectives: </strong>Evaluate mandibular cortical bone in childhood cancer survivors (CCS) and correlate findings with disease and treatment characteristics.</p><p><strong>Methods: </strong>Dental panoramic radiographs of 60 CCS and of 120 age and gender-matched healthy individuals were assessed by two independent observers. Bone was categorized as normal, moderately or severely eroded and its width was calculated at four sites bilaterally. Significant differences were tested using Chi-square and Pearson correlation co-efficient. Possible risk factors were detected by multivariate regression analysis.</p><p><strong>Results: </strong>Forty five percent of CCS had moderately eroded bone, while 67% of healthy individuals normal bone. Mean width was 3.9 mm in CCS (1.9 mm-6.4 mm) and 2.7 mm in healthy controls (1.4 mm-6 mm). None of the above differences were significant. Survivors diagnosed at a younger age had a five times greater probability of presenting mildly eroded bone.</p><p><strong>Conclusions: </strong>No direct effect of antineoplastic treatment on cortical bone could be demonstrated in the current study, underlying the need for more well-designed studies.</p>","PeriodicalId":56103,"journal":{"name":"Oral Radiology","volume":"39 4","pages":"811-820"},"PeriodicalIF":2.2,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10284492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}