Journal of Nippon Medical School最新文献_第8页

Relapse of Acquired Hemophilia A after COVID-19 Infection. 感染 COVID-19 后获得性血友病 A 复发。

IF 1 4区医学

Journal of Nippon Medical School Pub Date : 2024-01-20 Epub Date: 2023-02-21 DOI: 10.1272/jnms.JNMS.2023_90-609

Atsushi Marumo, Hisae Sugihara, Ikuko Omori, Eriko Morishita

{"title":"Relapse of Acquired Hemophilia A after COVID-19 Infection.","authors":"Atsushi Marumo, Hisae Sugihara, Ikuko Omori, Eriko Morishita","doi":"10.1272/jnms.JNMS.2023_90-609","DOIUrl":"10.1272/jnms.JNMS.2023_90-609","url":null,"abstract":"Acquired hemophilia A (AHA) is a rare disease in which an autoantibody causes bleeding by interacting with and inhibiting the coagulation activity of endogenous factor VIII (FVIII). Most cases of AHA are idiopathic; known causes include autoimmune diseases, malignant tumors, pregnancy, drugs, and viral infections. An 86-year-old man was diagnosed with AHA based on the following results: an activated partial thromboplastin time (aPTT) extension of 130.7 seconds, presence of an inhibitor pattern in a mixing study, an endogenous factor VIII (FVIII) level of <1%, and an FVIII inhibitor titer of >5.1 Bethesda units (BU). The activity of von Willebrand factor (vWF) was diminished (<10%), which was considered a complication of acquired von Willebrand syndrome (AVWS). The patient was started on prednisolone, and the inhibitor level eventually became negative. vWF values also became normal. However, 1 year later, he was hospitalized for treatment of coronavirus disease 2019 (COVID-19). Blood testing showed an aPTT extension of 110.5 seconds, FVIII level of 4%, and FVIII inhibitor titer of 0.8 BU; thus, a relapse of AHA was diagnosed. After administration of corticosteroid and remdesivir, he recovered from COVID-19 and AHA. The inhibitor level became negative on the 9th day of admission. Several studies have implicated COVID-19 infection and vaccination in AHA. We recommend that aPTT be measured when patients with AHA are infected with SARS-CoV2, to confirm AHA relapse.","PeriodicalId":56076,"journal":{"name":"Journal of Nippon Medical School","volume":" ","pages":"474-479"},"PeriodicalIF":1.0,"publicationDate":"2024-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10770378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Home-Based Rehabilitation on Renal Prognosis in Patients with Chronic Kidney Disease. 居家康复对慢性肾病患者肾脏预后的影响

IF 1.2 4区医学

Journal of Nippon Medical School Pub Date : 2024-01-01 DOI: 10.1272/jnms.JNMS.2024_91-508

Ayako Ikenouchi, Yukinao Sakai, Shouhei Wada, Yorito Yanagida, Tetsuya Kashiwagi, Masato Iwabu

{"title":"Impact of Home-Based Rehabilitation on Renal Prognosis in Patients with Chronic Kidney Disease.","authors":"Ayako Ikenouchi, Yukinao Sakai, Shouhei Wada, Yorito Yanagida, Tetsuya Kashiwagi, Masato Iwabu","doi":"10.1272/jnms.JNMS.2024_91-508","DOIUrl":"https://doi.org/10.1272/jnms.JNMS.2024_91-508","url":null,"abstract":"Background: The increasing prevalence of chronic kidney disease (CKD) requires effective preventive measures, particularly due to an aging population. This study aimed to assess the effectiveness of home visit rehabilitation in preventing renal function decline among patients with CKD.Method: In this retrospective study, patients with non-dialysis CKD undergoing home visit rehabilitation were compared with those receiving outpatient care at the Nippon Medical School Hospital between August 2017 and August 2023. Patients' backgrounds were matched using propensity scores derived from a logistic regression model. The primary endpoint was the annual change in the estimated glomerular filtration rate (eGFR), and the secondary endpoint was the annual change in blood parameters (Δblood urea nitrogen, Δcreatinine, Δtotal protein, Δalbumin, ΔC-reactive protein, Δhemoglobin, and Δhematocrit). Furthermore, the incidence of clinical outcomes, including mortality, hospitalization rate, and dialysis initiation rate, were analyzed within the additional 1-year observation period.Results: Overall, 128 patients (64 matched pairs) were analyzed. After a mean follow-up period of 12.7 ± 4.6 months, there was no significant difference in the eGFR between both groups (40.1 ± 13.7 vs. 37.8 ± 13.8 mL/min/1.73 m2, p = 0.36), but the annual decline in eGFR (%/year) was significantly lower in the rehabilitation group (-1.1 ± 29.8% vs. -11.8 ± 27.7%/year, p = 0.037). The annual change in the level of each blood test parameter and clinical outcomes were not significantly different between the two groups.Conclusion: Home-based rehabilitation interventions may mitigate the progression of renal impairment in patients with CKD.","PeriodicalId":56076,"journal":{"name":"Journal of Nippon Medical School","volume":"91 5","pages":"439-445"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142592304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Management of Asymptomatic Spontaneous Isolated Superior Mesenteric Artery Dissection and Morphology Features and Variations on Abdominal Contrast-Enhanced Computed Tomography: A Single-Center Experience. 无症状自发性孤立性肠系膜上动脉夹层的处理及腹部对比增强计算机断层扫描的形态特征和变化：单中心经验。

IF 1.2 4区医学

Journal of Nippon Medical School Pub Date : 2024-01-01 DOI: 10.1272/jnms.JNMS.2024_91-511

Yuko Kobayashi, Hidenori Yamaguchi, Takahiro Ando, Jin Tamai, Akira Yamamoto, Hiromitsu Hayashi, Shin-Ichiro Kumita

{"title":"Management of Asymptomatic Spontaneous Isolated Superior Mesenteric Artery Dissection and Morphology Features and Variations on Abdominal Contrast-Enhanced Computed Tomography: A Single-Center Experience.","authors":"Yuko Kobayashi, Hidenori Yamaguchi, Takahiro Ando, Jin Tamai, Akira Yamamoto, Hiromitsu Hayashi, Shin-Ichiro Kumita","doi":"10.1272/jnms.JNMS.2024_91-511","DOIUrl":"https://doi.org/10.1272/jnms.JNMS.2024_91-511","url":null,"abstract":"Background: Spontaneous isolated visceral artery dissection (SIVAD) is rare. Recently, appropriate treatment strategies for symptomatic SIVAD have been proposed. We aimed to determine the management of asymptomatic spontaneous isolated superior mesenteric artery dissection (ASISMAD), which is relatively frequently encountered in SIVAD.Methods: We retrospectively reviewed abdominal contrast-enhanced computed-tomography (CE-CT) scans from January 2015 to December 2020 in our institution and identified 24 patients with ASISMAD. Patient characteristics, vascular risk factors, complications, morphology features on CE-CT images, changes in abdominal CE-CT, and treatments outcomes were analyzed.Results: All patients were male. The mean age of the patients was 66.0 ± 8.9 (standard deviation) years, and the follow-up period was 24.8 ± 28.7 months. The CE-CT images revealed that 1 patient had periarterial fat stranding, 15 patients had aneurysmal dilatation, and 7 patients had branch vessel involvement. The mean length of the dissection was 19.9 ± 13.5 mm. The mean distance from the orifice of the superior mesenteric artery to the dissection origin point was 14.9 ± 8.8 mm. The mean branching angle was 54.8°± 19.7°. None of the patients had dissection-related abdominal symptoms or complications. Follow-up CE-CT scans showed progression of the dissection in 2 (8.3%), improvement in 2 (8.3%), stable dissection in 17 (70.9%), and complete remodeling in 3 (12.5%).Conclusions: Patients with ASISMAD do not require hospitalization because the pathology does not usually progress to visceral ischemia. Nevertheless, follow-up CE-CT is required because of progression of the dissection in rare cases.","PeriodicalId":56076,"journal":{"name":"Journal of Nippon Medical School","volume":"91 5","pages":"465-471"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142592306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dorsal Radiocarpal Dislocation with Radial Styloid Fracture Treated with Arthroscopy-Assisted Reduction and Internal Fixation: A Report of Two Cases. 关节镜辅助复位和内固定治疗桡骨背侧脱位伴桡骨髁骨折：两个病例的报告。

IF 1.2 4区医学

Journal of Nippon Medical School Pub Date : 2024-01-01 DOI: 10.1272/jnms.JNMS.2024_91-201

Yuji Tomori, Norie Kodera, Mitsuhiko Nanno, Tokifumi Majima

引用次数: 0

Association between Mobility of Residual Left Atrial Thrombus and Stroke Severity in Patients with Nonvalvular Atrial Fibrillation. 非瓣膜性心房颤动患者残留左心房血栓的移动性与中风严重程度之间的关系

IF 1.2 4区医学

Journal of Nippon Medical School Pub Date : 2024-01-01 DOI: 10.1272/jnms.JNMS.2024_91-311

Yuji Kato, Takeshi Hayashi, Shintaro Nakano, Takahide Arai, Shinako Fujiwara, Kaito Watanabe, Kiichiro Oryu, Ryutaro Kimura, Noriko Arai, Toru Nakagami, Ichiro Deguchi, Shinichi Takahashi, Satoshi Suda

{"title":"Association between Mobility of Residual Left Atrial Thrombus and Stroke Severity in Patients with Nonvalvular Atrial Fibrillation.","authors":"Yuji Kato, Takeshi Hayashi, Shintaro Nakano, Takahide Arai, Shinako Fujiwara, Kaito Watanabe, Kiichiro Oryu, Ryutaro Kimura, Noriko Arai, Toru Nakagami, Ichiro Deguchi, Shinichi Takahashi, Satoshi Suda","doi":"10.1272/jnms.JNMS.2024_91-311","DOIUrl":"https://doi.org/10.1272/jnms.JNMS.2024_91-311","url":null,"abstract":"Background: The differences in the characteristics of ischemic stroke associated with a mobile versus nonmobile residual left atrial thrombus (LAT) are unclear. We investigated whether the mobility of an LAT detected by transthoracic echocardiography is associated with the clinical features of stroke.Methods: This study included 20 consecutive patients with nonvalvular atrial fibrillation who were admitted to our hospital for treatment of acute ischemic stroke and then found to have an LAT on transthoracic echocardiography. The patients were divided into two groups: those with a mobile LAT (Group M) and those with a nonmobile LAT (Group N). The clinical, neuroradiological, and echocardiographic variables were assessed.Results: The LAT was mobile in 11 patients (Group M) and nonmobile in nine patients (Group N). The median National Institutes of Health Stroke Scale score on admission was higher in Group M than N (17 vs. 7, respectively; p=0.196). Four patients in Group M and one in Group N developed in-hospital stroke recurrence (36% vs. 11%, respectively; p=0.319). The prevalence of large vessel occlusion (15 events in Group M and 10 events in Group N, including in-hospital recurrent events) was significantly higher in Group M than N (73% vs. 30%, respectively; p=0.049), which seemed to lead to poorer functional outcomes in Group M than N (ratio of modified Rankin scale score of 0-2 at discharge: 18% vs. 44%, respectively; p=0.336).Conclusions: The mobility of LAT may affect stroke severity in patients with nonvalvular atrial fibrillation.","PeriodicalId":56076,"journal":{"name":"Journal of Nippon Medical School","volume":"91 3","pages":"322-327"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141556034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preoperative Risk Factor Analysis of Prolonged Retroperitoneoscopic Radical Nephrectomy. 腹膜后腔镜根治性肾切除术的术前风险因素分析

IF 1.2 4区医学

Journal of Nippon Medical School Pub Date : 2024-01-01 DOI: 10.1272/jnms.JNMS.2024_91-407

Masato Yanagi, Tsutomu Hamasaki, Tetsuro Sekine, Jun Akatsuka, Yuki Endo, Hayato Takeda, Taiji Nishimura, Yukihiro Kondo

{"title":"Preoperative Risk Factor Analysis of Prolonged Retroperitoneoscopic Radical Nephrectomy.","authors":"Masato Yanagi, Tsutomu Hamasaki, Tetsuro Sekine, Jun Akatsuka, Yuki Endo, Hayato Takeda, Taiji Nishimura, Yukihiro Kondo","doi":"10.1272/jnms.JNMS.2024_91-407","DOIUrl":"https://doi.org/10.1272/jnms.JNMS.2024_91-407","url":null,"abstract":"Background: This study aimed to investigate the preoperative risk factors for prolonged operating time in retroperitoneoscopic radical nephrectomy (RRN) for renal cell carcinoma (RCC).Methods: We retrospectively reviewed patients treated for RRN between January 2015 and December 2021. Clinical data, including radiological findings such as visceral fat area (VFA), subcutaneous fat area (SFA), and posterior perirenal fat thickness (PFT) were collected. The operating time for RRN was analyzed using univariate and multivariate logistic regression analyses.Results: A total of 79 patients were included. The median age was 66 (range: 28-88) years and 48 (60.8%) had right-sided tumors. The median tumor size was 52 (range: 12-100) mm. Median BMI, VFA, SFA, and posterior PFT were 22.9 (range: 16.3-42.2) kg/m2, 102 (range: 14-290) cm2, 124 (range: 33-530) cm2, and 6 (range: 1-35) mm. The median operating time was 248 (range: 140-458) min. Univariate logistic regression analyses revealed that a right tumor (p=0.046), tumor size >7 cm (p=0.010), and posterior PFT >25 mm (p=0.006) were preoperative risk factors for prolonged operating time in RRN. Multivariate logistic regression analyses revealed that a posterior PFT of >25 mm was an independent preoperative risk factor for prolonged operating time for RRN (p=0.008, OR: 7.29, 95% CI: 1.69-31.5).Conclusions: A posterior PFT >25 mm was an independent preoperative risk factor for the operating time of RRN. In RRN, for patients with a posterior PFT >25 mm, surgeons should develop surgical strategies, including the selection of a transperitoneal approach to surgery, to avoid prolonging the operating time.","PeriodicalId":56076,"journal":{"name":"Journal of Nippon Medical School","volume":"91 4","pages":"377-382"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unilateral Vocal Cord Paralysis in a Patient with Anti-Galactocerebroside Antibodies: A Case Report. 抗半乳糖脑苷脂抗体患者的单侧声带麻痹：病例报告

IF 1.2 4区医学

Journal of Nippon Medical School Pub Date : 2024-01-01 DOI: 10.1272/jnms.JNMS.2024_91-402

Masaru Yanagihashi, Ryuichi Okamoto, Ayano Matsuoka, Harumi Morioka, Akira Fukuo, Kota Wada, Osamu Kano

引用次数: 0

Organizing Pneumonia Associated with Pneumocystis jirovecii in a Patient Receiving Dose-Dense Chemotherapy for Breast Cancer: A Case Report. 在接受剂量密集化疗的乳腺癌患者中，组织性肺炎与乙氏肺囊虫相关：1例报告。

IF 1.2 4区医学

Journal of Nippon Medical School Pub Date : 2024-01-01 DOI: 10.1272/jnms.JNMS.2024_91-605

Mio Yagi, Toshihiko Yoneto, Keiko Yanagihara, Koji Nagata, Satoru Matsuki, Hiroyuki Takei

{"title":"Organizing Pneumonia Associated with Pneumocystis jirovecii in a Patient Receiving Dose-Dense Chemotherapy for Breast Cancer: A Case Report.","authors":"Mio Yagi, Toshihiko Yoneto, Keiko Yanagihara, Koji Nagata, Satoru Matsuki, Hiroyuki Takei","doi":"10.1272/jnms.JNMS.2024_91-605","DOIUrl":"https://doi.org/10.1272/jnms.JNMS.2024_91-605","url":null,"abstract":"In patients not infected by HIV, Pneumocystis jirovecii pneumonia (PCP) is characterized by rapid disease progression, difficulty in confirming the diagnosis, and poor prognosis. PCP has also been reported in immunocompromised patients receiving chemotherapy, most often for hematologic tumors, although some patients receiving treatment for breast cancer have been affected. Dose-dense chemotherapy (DDC) which is performed with shorter dosing intervals than standard chemotherapy and is now widely used in clinical practice. However, adverse events have been reported, including infections associated with decreased immune status. PCP infection is considerably more challenging to diagnose and treat than bacterial or viral infections. Furthermore, organizing pneumonia (OP), a pulmonary lesion of PCP, is infrequent and requires caution on the part of clinicians, as protozoan infections require different forms of treatment. Although we initially suspected bacterial, viral, and drug-induced pneumonia in our patient and started treatment with antibiotics, antifungals, and prednisolone, the final diagnosis was OP. The pulmonary lesion of PCP was treated with systemic corticosteroids, leading to recovery. There have been no similar reports of PCP during chemotherapy for malignant disease; however, the possibility of OP should be considered during chemotherapy. Herein, we report a case of PCP during preoperative DDC for advanced breast cancer.","PeriodicalId":56076,"journal":{"name":"Journal of Nippon Medical School","volume":"91 6","pages":"567-573"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prognostic Factors for Mortality in Maintenance Hemodialysis Patients Infected with SARS-CoV-2. SARS-CoV-2感染维持性血液透析患者死亡的预后因素分析

IF 1.2 4区医学

Journal of Nippon Medical School Pub Date : 2024-01-01 DOI: 10.1272/jnms.JNMS.2024_91-611

Takehisa Yamada, Yukinao Sakai, Tetsuya Kashiwagi, Masato Iwabu

{"title":"Prognostic Factors for Mortality in Maintenance Hemodialysis Patients Infected with SARS-CoV-2.","authors":"Takehisa Yamada, Yukinao Sakai, Tetsuya Kashiwagi, Masato Iwabu","doi":"10.1272/jnms.JNMS.2024_91-611","DOIUrl":"10.1272/jnms.JNMS.2024_91-611","url":null,"abstract":"Background: Maintenance hemodialysis patients are immunosuppressed, which increases their mortality risk if they contract coronavirus disease 2019 (COVID-19).Methods: We studied data from 36 consecutive patients undergoing maintenance hemodialysis who were diagnosed as having COVID-19 from January 2020 to September 2023. Clinical data such as age and sex, laboratory data, radiological findings, modalities for blood purification therapy, and outcome at the time of discharge were collected from their hospital records. Binomial logistic regression analysis was used to predict risk factors for mortality and continuous hemodiafiltration (CHDF).Results: After analyzing the correlation of outcomes with each prognostic factor, we identified 6 significant factors (P < 0.05). Age and initiation of CHDF were both associated with mortality. COVID-19 severity, steroid treatment, and serum lactate dehydrogenase level at admission were positively correlated with risk for CHDF initiation, while a greater number of vaccine doses was associated with lower risk.Conclusions: Elderly hemodialysis patients have a higher mortality risk if they develop COVID-19 and require CHDF. More attention is warranted for vulnerable older patients with COVID-19 if they require hemodialysis. Risk reduction strategies, such as appropriate vaccination, are necessary.","PeriodicalId":56076,"journal":{"name":"Journal of Nippon Medical School","volume":"91 6","pages":"520-526"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reconstruction Using Negative Pressure Wound Therapy with a Cotton Filler for Fixation of Male Genital Skin Grafts in Cases of Fournier's Gangrene. 负压创面及棉填充物修复男性生殖器皮肤移植固定富尼耶坏疽病例。

IF 1.2 4区医学

Journal of Nippon Medical School Pub Date : 2024-01-01 DOI: 10.1272/jnms.JNMS.2024_91-610

Yuki Ideguchi, Shimpei Ono, Shintaro Kaneyuku, Taishi Murakami, Rei Ogawa

{"title":"Reconstruction Using Negative Pressure Wound Therapy with a Cotton Filler for Fixation of Male Genital Skin Grafts in Cases of Fournier's Gangrene.","authors":"Yuki Ideguchi, Shimpei Ono, Shintaro Kaneyuku, Taishi Murakami, Rei Ogawa","doi":"10.1272/jnms.JNMS.2024_91-610","DOIUrl":"https://doi.org/10.1272/jnms.JNMS.2024_91-610","url":null,"abstract":"The reliable engraftment of skin grafts into areas with complex shapes can be challenging. Here, we report a case of successful fixation of a genital skin graft using negative pressure wound therapy (NPWT) with RENASYS® Cotton Filler. A 44-year-old male with no relevant medical history underwent split-thickness skin grafting for a genital skin defect caused by Fournier's gangrene. A 0.4-mm sheet graft was applied for the penile skin defect, while 0.4-mm 1.5 times mesh grafting was applied for the testis and spermatic cord. NPWT with a cotton filler was used for seven days of fixation. No postoperative pain or stool contamination was observed. Although a small area of partial necrosis developed, the lesion healed with conservative treatment. Six months after surgery, there was no scar contracture, urination disorder, or pain during erection. Cotton fillers are highly malleable and adaptable, allowing for simple and reliable fixation of skin grafts in complex areas. Moreover, NPWT for genital graft fixation avoids contamination from stools. Therefore, we recommend fixation using NPWT with a cotton filler for genital skin grafting.","PeriodicalId":56076,"journal":{"name":"Journal of Nippon Medical School","volume":"91 6","pages":"595-599"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0