Best Practice & Research Clinical Gastroenterology最新文献_第2页

Progress, pitfalls, and the path forward of endoscopic submucosal dissection in the United States 内镜下粘膜剥离术在美国的进展、缺陷和发展方向

IF 5.2 3区医学

Best Practice & Research Clinical Gastroenterology Pub Date : 2026-06-01 Epub Date: 2026-05-01 DOI: 10.1016/j.bpg.2026.102106

Saurabh Chandan, Abdullah Abbasi, Harsimran Kalsi, Sahib Singh, Peter V. Draganov, Dennis Yang

引用次数: 0

Copyright Information 版权信息

IF 5.2 3区医学

Best Practice & Research Clinical Gastroenterology Pub Date : 2026-06-01 Epub Date: 2026-08-26 DOI: 10.1016/S1521-6918(26)00047-8

引用次数: 0

Endoscopic approach to the large non-pedunculated colorectal polyp: mucosal, submucosal, hot and cold techniques 大无带蒂结直肠息肉的内镜入路：粘膜、粘膜下、热技术和冷技术

IF 5.2 3区医学

Best Practice & Research Clinical Gastroenterology Pub Date : 2026-06-01 Epub Date: 2026-05-06 DOI: 10.1016/j.bpg.2026.102108

Anthony Whitfield, Mayan Eitan, Michael J. Bourke

引用次数: 0

Colorectal ESD from basics to latest innovations! 结肠直肠ESD从基础到最新创新！

IF 5.2 3区医学

Best Practice & Research Clinical Gastroenterology Pub Date : 2026-06-01 Epub Date: 2026-05-17 DOI: 10.1016/j.bpg.2026.102113

Ludovico Alfarone, Mathieu Pioche, Roberto de Sire, Alessandro Repici, Jeremie Jacques

{"title":"Colorectal ESD from basics to latest innovations!","authors":"Ludovico Alfarone, Mathieu Pioche, Roberto de Sire, Alessandro Repici, Jeremie Jacques","doi":"10.1016/j.bpg.2026.102113","DOIUrl":"10.1016/j.bpg.2026.102113","url":null,"abstract":"<div><div>Colorectal endoscopic submucosal dissection (ESD) is gaining adoption in Western practice because it outperforms endoscopic mucosal resection (EMR), with higher en bloc and R0 resection rates, lower local recurrence, and less need for surgery. Its main limitation is technical: colorectal ESD is long, complex, and complication-prone. Multiple recent advances aim to improve reproducibility and safety, including new dissection strategies (pocket-creation, tunneling, underwater ESD), traction systems (clip-band, adaptive and magnetic traction), advanced knives (a novel thin-needle knife with high-pressure waterjet) and closure platforms (reopenable clip with anchor prongs, through-the-scope helix tack-and-suture system and endoscopic hand suturing), stabilizing platforms, and robotic and AI assistance. Safe ESD still depends on fundamental skills: tip control, stable incision and trimming, efficient submucosal dissection, and immediate control of bleeding and perforation. This review aims to summarize current technical solutions, identify persistent limitations, and define priorities for training, case selection, cost-effectiveness, and environmental impact in Western practice.</div></div>","PeriodicalId":56031,"journal":{"name":"Best Practice & Research Clinical Gastroenterology","volume":"82 ","pages":"Article 102113"},"PeriodicalIF":5.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148810741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

What is next? Management following endoscopic resection of barrett neoplasia - Controversies and shifting paradigms 下一步是什么？内镜下巴雷特瘤切除术后的处理-争议和转变的范例

IF 5.2 3区医学

Best Practice & Research Clinical Gastroenterology Pub Date : 2026-06-01 Epub Date: 2026-03-06 DOI: 10.1016/j.bpg.2026.102099

Laura S. Boer, Bas L.A.M. Weusten, Roos E. Pouw

{"title":"What is next? Management following endoscopic resection of barrett neoplasia - Controversies and shifting paradigms","authors":"Laura S. Boer, Bas L.A.M. Weusten, Roos E. Pouw","doi":"10.1016/j.bpg.2026.102099","DOIUrl":"10.1016/j.bpg.2026.102099","url":null,"abstract":"<div><div>Endoscopic resection (ER) is recommended for patients with a visible lesion in Barrett esophagus containing low-grade dysplasia, high-grade dysplasia, or T1 esophageal adenocarcinoma (EAC). ER is considered curative if the resection margins are free from neoplasia and no high-risk histological features, such as deep submucosal invasion, (lympho)vascular invasion, or poor tumour differentiation, are present. Subsequent ablation of the remaining Barrett segment is typically advised to prevent development of metachronous neoplasia. However, in a subset of patients, histopathology may reveal vertical tumour-positive resection margins or high-risk features of EAC. In such cases, management options traditionally involved esophagectomy and/or ((neo)adjuvant) chemo/radiotherapy due to the risk of local recurrence and lymph node metastasis, but strict endoscopic follow-up is increasingly being recognized as alternative approach. This review explores current evidence, controversies, and evolving strategies in the management following an ER for Barrett-related neoplasia.</div></div>","PeriodicalId":56031,"journal":{"name":"Best Practice & Research Clinical Gastroenterology","volume":"82 ","pages":"Article 102099"},"PeriodicalIF":5.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148810752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Predictive risk models for the diagnosis and cancer progression of pancreatic cysts 胰腺囊肿诊断和癌症进展的预测风险模型

IF 4 3区医学

Best Practice & Research Clinical Gastroenterology Pub Date : 2026-03-01 Epub Date: 2026-03-27 DOI: 10.1016/j.bpg.2026.102101

Luís Marques Loureiro, Michael Fernandez Y Viesca, Marianna Arvanitakis

引用次数: 0

Needle-based confocal laser endomicroscopy and artificial intelligence in pancreatic cystic lesions: Insights and clinical advances 针基共聚焦激光内镜和人工智能在胰腺囊性病变中的应用：见解和临床进展

IF 4 3区医学

Best Practice & Research Clinical Gastroenterology Pub Date : 2026-03-01 Epub Date: 2025-12-15 DOI: 10.1016/j.bpg.2025.102085

Ahmed Abdelbaki , Tassiana Maloof , Steve Serrao , David Guevara-Lazo , Somashekar G. Krishna

{"title":"Needle-based confocal laser endomicroscopy and artificial intelligence in pancreatic cystic lesions: Insights and clinical advances","authors":"Ahmed Abdelbaki , Tassiana Maloof , Steve Serrao , David Guevara-Lazo , Somashekar G. Krishna","doi":"10.1016/j.bpg.2025.102085","DOIUrl":"10.1016/j.bpg.2025.102085","url":null,"abstract":"<div><h3>Purpose of the review</h3><div>To summarize recent advances in diagnosing and managing pancreatic cystic lesions (PCLs) with needle-based confocal laser endomicroscopy (nCLE), focusing on its principles, applications, safety, limitations, and the emerging role of artificial intelligence (AI).</div></div><div><h3>Findings</h3><div>Endoscopic ultrasound (EUS)-guided nCLE allows real-time, high-resolution imaging of PCL epithelium, improving diagnostic accuracy over conventional methods such as cross-sectional imaging and cyst fluid analysis. Prospective studies and derivative analyses have validated nCLE as a reliable tool for differentiating mucinous from non-mucinous PCLs, identifying subtypes, and detecting advanced neoplasia in mucinous PCLs. Artificial intelligence (AI) integration in nCLE imaging improves sensitivity for advanced neoplasia detection, furthering precision PCL evaluation. Safety data show slightly higher but mostly mild, self-limited complications.</div></div><div><h3>Summary</h3><div>EUS-nCLE has transformed real-time evaluation of PCLs, enabling accurate diagnosis and risk stratification. AI adoption promises standardized interpretation and efficiency. Future research should validate AI tools, integrate multidisciplinary approaches, and assess long-term outcomes.</div></div>","PeriodicalId":56031,"journal":{"name":"Best Practice & Research Clinical Gastroenterology","volume":"81 ","pages":"Article 102085"},"PeriodicalIF":4.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147979380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Copyright Information 版权信息

IF 4 3区医学

Best Practice & Research Clinical Gastroenterology Pub Date : 2026-03-01 Epub Date: 2026-05-20 DOI: 10.1016/S1521-6918(26)00021-1

引用次数: 0

Pancreatic cystic lesions in hereditary syndromes: Diagnostic role of endoscopic ultrasound 胰腺囊性病变遗传性综合征：内镜超声的诊断作用

IF 4 3区医学

Best Practice & Research Clinical Gastroenterology Pub Date : 2026-03-01 Epub Date: 2026-04-16 DOI: 10.1016/j.bpg.2026.102102

Katarzyna M. Pawlak , Mateusz Jagielski , Ioannis S. Papanikolaou , Wandong Hong , Jacek Piątkowski , Marek Jackowski

{"title":"Pancreatic cystic lesions in hereditary syndromes: Diagnostic role of endoscopic ultrasound","authors":"Katarzyna M. Pawlak , Mateusz Jagielski , Ioannis S. Papanikolaou , Wandong Hong , Jacek Piątkowski , Marek Jackowski","doi":"10.1016/j.bpg.2026.102102","DOIUrl":"10.1016/j.bpg.2026.102102","url":null,"abstract":"<div><div>Pancreatic cystic lesions (PCLs) may occur in several hereditary syndromes, although their frequency, phenotype, and clinical implications differ considerably across entities. This review summarizes the spectrum of hereditary-associated PCLs, focusing on von Hippel–Lindau syndrome, autosomal dominant polycystic kidney disease, cystic fibrosis, multiple endocrine neoplasia type 1, and other hereditary pancreatic cancer predisposition syndromes.</div><div>The lesions most commonly encountered are simple cysts, serous cystic neoplasms, and intraductal papillary mucinous neoplasms, whereas cystic pancreatic neuroendocrine tumors are less frequent. In some cases, pancreatic cystic lesions may represent the first or only manifestation of an underlying hereditary disorder.</div><div>The endosonographic morphology of hereditary-associated PCLs is generally comparable to that seen in sporadic lesions, making clinical and genetic context essential for interpretation. EUS with fluid aspiration remains central to evaluation, while cyst-fluid next-generation sequencing may provide added value when imaging, cytology, and standard fluid analysis are inconclusive. Molecular testing may improve cyst classification, support risk stratification, and occasionally reveal lesion-specific alterations suggestive of a hereditary background.</div><div>Although IPMNs appear to be more prevalent in hereditary pancreatic cancer syndromes and familial pancreatic cancer kindreds, their malignant potential relative to sporadic IPMNs remains uncertain. At present, surveillance should therefore follow syndrome-specific recommendations together with existing guideline-based management of pancreatic cysts, pending further studies to better define natural history and optimal follow-up strategies in hereditary settings.</div></div>","PeriodicalId":56031,"journal":{"name":"Best Practice & Research Clinical Gastroenterology","volume":"81 ","pages":"Article 102102"},"PeriodicalIF":4.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147979327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Imaging assessment and radiological features of pancreatic cystic lesions 胰腺囊性病变的影像学评价及影像学特征

IF 4 3区医学

Best Practice & Research Clinical Gastroenterology Pub Date : 2026-03-01 Epub Date: 2025-10-15 DOI: 10.1016/j.bpg.2025.102053

Nicolò Brandi , Emanuela Giampalma , Riccardo Inchingolo , Onofrio Antonio Catalano , Marco Midulla , Matteo Renzulli

引用次数: 0